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COVID-19: room for treating T cell exhaustion?
Position: 17003 (18 views)
The role of environmental factors to transmission of SARS-CoV-2 (COVID-19)
Abstract The current outbreak of the novel coronavirus disease 2019 (COVID-19) in more than 250 countries has become a serious threat to the health of people around the world. Human-to-human transmission of the Severe acute respiratory syndrome…
Position: 18618 (16 views)
Recruitability and effect of PEEP in SARS-Cov-2-associated acute respiratory distress syndrome
Abstract Background A large proportion of patients with a SARS-Cov-2-associated respiratory failure develop an acute respiratory distress syndrome (ARDS). It has been recently suggested that SARS-Cov-2-associated ARDS may differ from usual…
Position: 8728 (27 views)
Deubiquitinating Enzymes in Coronaviruses and Possible Therapeutic Opportunities for COVID-19
Following the outbreak of novel severe acute respiratory syndrome (SARS)-coronavirus (CoV)2, the majority of nations are struggling with countermeasures to fight infection, prevent spread and improve patient survival. Considering that the pandemic is…
Position: 16098 (19 views)
The Need for the Right Socio-Economic and Cultural Fit in the COVID-19 Response in Sub-Saharan Africa: Examining Demographic, Economic Political, Health, and Socio-Cultural Differentials in COVID-19 Morbidity and Mortality
The coronavirus disease (COVID-19) has spread quickly across the globe with devastating effects on the global economy as well as the regional and societies’ socio-economic fabrics and the way of life for vast populations. The nonhomogeneous continent…
Position: 17846 (17 views)
Battling COVID-19 Pandemic: Sphingosine-1-Phosphate Analogs as an Adjunctive Therapy?
With the sudden outbreak of COVID-19 patient worldwide and associated mortality, it is critical to come up with an effective treatment against SARS-CoV-2. Studies suggest that mortality due to COVID 19 is mainly attributed to the hyper inflammatory…
Position: 14090 (21 views)
Recent Insight into SARS-CoV2 Immunopathology and Rationale for Potential Treatment and Preventive Strategies in COVID-19
As the outbreak of the new coronavirus (SARS-CoV-2) infection is spreading globally, great effort is being made to understand the disease pathogenesis and host factors that predispose to disease progression in an attempt to find a window of…
Position: 19224 (15 views)
COVID-19: An Update About the Discovery Clinical Trial
Finding efficacious and safe treatments for COVID-19 emerges as a crucial need in order to control the spread of the pandemic. Whereas plasma therapy attracts much interest, the European project Discovery focuses on the potentialities of small…
Position: 15152 (20 views)
Forecasting the Spread of COVID-19 in Kuwait Using Compartmental and Logistic Regression Models
The state of Kuwait is facing a substantial challenge in responding to the spread of the novel coronavirus 2019 (COVID-19). The government’s decision to repatriate stranded citizens back to Kuwait from various COVID-19 epicenters has generated a…
Position: 12093 (23 views)
Is SARS-CoV-2 Vertically Transmitted?
At the end of 2019, in Wuhan (China), the onset of a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was observed. The disease, named COVID-19, has a wide spectrum of clinical presentations, ranging from asymptomatic or…
Position: 12093 (23 views)