260 10 20655 https://www.socictopen.socict.org/files/original/e690d2839fd6324c0a95a757165d53eb.pdf f492c04af25737a34e81cd61820ec517 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The role of passive immunization in the age of SARS-CoV-2: an update Creator An entity primarily responsible for making the resource Martijn van Griensven, Marion Schneider, Dieter Häussinger, Artur Lichtenberg, Wilfried Budach, Johannes C. Fischer, Hubert Schelzig, Wolfram Trudo Knoefel, Kurt Zänker, Ute Ganswindt, Stefanie Corradini, Edwin Bölke, Torsten Feldt, Christiane Matuschek, Jan Haussmann, Bálint Tamaskovics, Freddy-Joel Djiepmo-Njanang, Detlef Kindgen-Milles, Hans Bojar, Matthias Peiper Description An account of the resource Abstract The rapid spread of the corona virus pandemic is an existential problem for many people in numerous countries. So far, there is no effective vaccine protection or proven therapy available against the SARS-CoV-2 virus. In this review, we describe the role of passive immunization in times of the corona virus. Passive immunization could be a bridging technology to improve the immune defense of critically ill patients until better approaches with effective medications are available. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Intensive care unit, high-risk, Respiratory failure, convalescent plasma, COVID-19, bridge therapy Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/s40001-020-00414-5 Source A related resource from which the described resource is derived European Journal of Medical Research Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine https://www.socictopen.socict.org/files/original/e8f4fc54d401ac1de68ab76e5c0366fc.pdf f6b9d848f392cd00777332fb39414195 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Effects of the COVID-19 pandemic on life scientists Creator An entity primarily responsible for making the resource Oliver Stegle, Jan O. Korbel Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/s13059-020-02031-1 Source A related resource from which the described resource is derived Genome Biology Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General), Genetics https://www.socictopen.socict.org/files/original/bc6386b76d1451a5898a0a79f6a41dc0.pdf 5226aa4ebcf4c5e29f0c77e998e74e58 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New Coronavirus (2019-nCoV): An Insight Toward Preventive Actions and Natural Medicine Creator An entity primarily responsible for making the resource Leila Khedmat Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource coronavirus, disease prevention, Health Improvement, COVID-19, viral infection epidemic, diet supplemenation Identifier An unambiguous reference to the resource within a given context DOI: 10.34172/ijtmgh.2020.07 Source A related resource from which the described resource is derived International Journal of Travel Medicine and Global Health Publisher An entity responsible for making the resource available International Travel Medicine Center of Iran Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine https://www.socictopen.socict.org/files/original/21aaac0fed60737fa8d1611c1fc93fc3.pdf ee19e07beece970ecfc3bf14b2283fc6 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource AN EARLY ASSESSMENT OF THE EFFICACY OF MEDICINES IN THE TREATMENT OF PATIENTS WITH COVID - 19 Creator An entity primarily responsible for making the resource A. S. Kolbin Description An account of the resource Coronavirus disease-2019 is considered the very recent challenge to world community. While still lacking specific vaccines, the healthcare system is in urgent need for effective and safe medical drugs. We have evaluated the medical technologies for COVID-19 which are under study now. The search was conducted on СlinicalTrials.gov until the start of April 2020. Hence, it was shown that the worldwide rise in new clinical trials concerning COVID-19 is increasing by 65% per week. The interventional Phase II and III clinical trials are more often performed. Most studies are scheduled or conducted in Western Europe (n = 92), China (n = 79), and the United States (n = 51). Surrogate outcome points are usually evaluated, such as clinical recovery, recovery based on clinical scores of symptoms (fever, cough, diarrhea, myalgia, shortness of breath), lack of dyspnea progression, rate of artificial ventilation, rates of admission to the ICU, etc. Antimalarial drugs that are mostly studied. At the present time, it is not possible to discuss efficacy and safety of any drug in the COVID-19 treatment, since most studies are launched quiet recently. The therapeutic regimens proposed now in clinical recommendations are not evidence-based, and appropriate studies are, at best, still considered hypothetic. Date A point or period of time associated with an event in the lifecycle of the resource 2019 Subject The topic of the resource chloroquine, Clinical trials, Monoclonal Antibodies, hydroxychloroquine, Lopinavir/ritonavir, Coronavirus infection, remdesivir, COVID-19 Identifier An unambiguous reference to the resource within a given context DOI: 10.15789/2220-7619-AEA-1458 Source A related resource from which the described resource is derived Infekciâ i Immunitet Publisher An entity responsible for making the resource available Sankt-Peterburg : NIIÈM imeni Pastera Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases https://www.socictopen.socict.org/files/original/8636835413a3f8b4d462d8cb18b87ebf.pdf 32efb1b9ae0a8eb51d751d939d74e047 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Gendered Understanding of Ebola Crisis in Sierra Leone. Lessons for COVID-19 Creator An entity primarily responsible for making the resource Ana Androsik Description An account of the resource This case study provides evidence in response to the research question: “How did males and females in the bottom of the socio-economic hierarchy i.e. rural poor, respond to the 2014/2015 Ebola outbreak in Sierra Leone?” This case study focuses on the following research sub-questions: • Caretaking Responsibilities: What kind of additional burdens were placed on rural men and women who took on the responsibility for orphaned children? • Income Earnings: How did market closures and restrictions on movements affect income earnings of males and females in the rural area? Based on the analysis of the Ebola crisis on rural poor men and women income and caretaking responsibilities highlighted in this case study, we can state that most women bore the costs of caretaking responsibilities. However, both women and men of Sierra Leone bore serious socio-economic costs at the level of their productive labor (income in this case study). The international community is presently dealing with the effect of the COVID-19 pandemic on marginalized communities, and the outcomes are still unknown. This brief case study helps to understand the gendered outcomes of previous public health epidemics in the context of social stratification. It is likely that many international humanitarian organizations will eventually aim at building economic and social resilience of impoverished communities with the focus on specific needs of different genders. An evidence from previous public health crises on the economy can help design the most efficient program interventions. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context DOI: 10.3897/popecon.4.e53301 Source A related resource from which the described resource is derived Население и экономика Publisher An entity responsible for making the resource available Moscow State University, Faculty of Economics Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Economic theory. Demography https://www.socictopen.socict.org/files/original/7a242e5671089cc00133b893d0e2cbb0.pdf 751d96f87c7b8bf8067560dc973c5eae Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource COVID-19 in Africa: care and protection for frontline healthcare workers Creator An entity primarily responsible for making the resource Helen Rees, Matthew F. Chersich, Glenda Gray, Lee Fairlie, Greg Simpson, Marjan Mosalman Haghighi, Stanley Luchters, Brian Allwood, Quentin Eichbaum, Fiona Scorgie, Susannah Mayhew, Minh Duc Pham, René English Description An account of the resource Abstract Medical staff caring for COVID-19 patients face mental stress, physical exhaustion, separation from families, stigma, and the pain of losing patients and colleagues. Many of them have acquired SARS-CoV-2 and some have died. In Africa, where the pandemic is escalating, there are major gaps in response capacity, especially in human resources and protective equipment. We examine these challenges and propose interventions to protect healthcare workers on the continent, drawing on articles identified on Medline (Pubmed) in a search on 24 March 2020. Global jostling means that supplies of personal protective equipment are limited in Africa. Even low-cost interventions such as facemasks for patients with a cough and water supplies for handwashing may be challenging, as is ‘physical distancing’ in overcrowded primary health care clinics. Without adequate protection, COVID-19 mortality may be high among healthcare workers and their family in Africa given limited critical care beds and difficulties in transporting ill healthcare workers from rural to urban care centres. Much can be done to protect healthcare workers, however. The continent has learnt invaluable lessons from Ebola and HIV control. HIV counselors and community healthcare workers are key resources, and could promote social distancing and related interventions, dispel myths, support healthcare workers, perform symptom screening and trace contacts. Staff motivation and retention may be enhanced through carefully managed risk ‘allowances’ or compensation. International support with personnel and protective equipment, especially from China, could turn the pandemic’s trajectory in Africa around. Telemedicine holds promise as it rationalises human resources and reduces patient contact and thus infection risks. Importantly, healthcare workers, using their authoritative voice, can promote effective COVID-19 policies and prioritization of their safety. Prioritizing healthcare workers for SARS-CoV-2 testing, hospital beds and targeted research, as well as ensuring that public figures and the population acknowledge the commitment of healthcare workers may help to maintain morale. Clearly there are multiple ways that international support and national commitment could help safeguard healthcare workers in Africa, essential for limiting the pandemic’s potentially devastating heath, socio-economic and security impacts on the continent. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Mental health, infection control, Africa, healthcare workers, Human Resources for Health, SARS-CoV-2, COVID-19 Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/s12992-020-00574-3 Source A related resource from which the described resource is derived Globalization and Health Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Public aspects of medicine https://www.socictopen.socict.org/files/original/6c28dac3500f624e4821c762d9dcb85f.pdf 7dcfeead0d49991deb3c53a9dfad987d Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Impact of international travel dynamics on domestic spread of 2019-nCoV in India: origin-based risk assessment in importation of infected travelers Creator An entity primarily responsible for making the resource Sachin S. Gunthe, Satya S. Patra Description An account of the resource Abstract The recent pandemic caused by the 2019 outbreak of novel coronavirus (2019-nCoV or COVID-19) has affected more than 3.0 million people resulting ~ 212,000 deaths across 215 countries/territories as on 28th April 2020. The importation of the cases owing to enormous international travels from the affected countries is the foremost reason for local cycle of transmission. For a country like India, the second most populous country in the world with ~ 1.35 billion population, the management and control of 2019-nCoV domestic spread heavily relied on effective screening and strict quarantine of passengers arriving at various international airports in India from affected countries. Here, by extracting the data from FLIRT, an online airline database for more than 800 airlines, and scanning more than 180,000 flights and 39.9 million corresponding passenger seats during 4th – 25th March, we show that India experienced the highest risk index of importing the passengers from middle eastern airports. Contrary to perception, travelers from China imposed lowest risk of importing the infected cases in India. This is clearly evident form the fact that while the number of infected cases were on the peak in China India was one of the least affected countries. The number of cases in India started exhibiting a sharp increase in the infected cases only after the European countries and USA recorded large number of infected cases. We further argue that while the number of cases in middle eastern countries may still be very low, the airports in middle eastern countries, particularly Dubai, being one of the largest transit hubs for international passengers, including arriving in India, might have posed a higher risk of getting infected with 2019-nCoV. We suggest that any future travel related disease infection screening at the airports should critically assess the passengers from major transit hubs in addition to affected country of origin. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource India, airport screening, COVID-19, Travel risk assessment Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/s12992-020-00575-2 Source A related resource from which the described resource is derived Globalization and Health Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Public aspects of medicine https://www.socictopen.socict.org/files/original/b0357cd2c27317d1a5b3642de1082b2f.pdf 609fa312dbfc304affca405d9a1eb4a1 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The use of internet analytics by a Canadian provincial chiropractic regulator to monitor, evaluate and remediate misleading claims regarding specific health conditions, pregnancy, and COVID-19 Creator An entity primarily responsible for making the resource Jan Hartvigsen, Greg Kawchuk, J. Keith Simpson, Stan Innes, Brian Gushaty Description An account of the resource Abstract Background Internet analytics are increasingly being integrated into public health regulation. One specific application is to monitor compliance of website and social media activity with respect to jurisdictional regulations. These data may then identify breaches of compliance and inform disciplinary actions. Our study aimed to evaluate the novel use of internet analytics by a Canadian chiropractic regulator to determine their registrants compliance with three regulations related to specific health conditions, pregnancy conditions and most recently, claims of improved immunity during the COVID-19 crisis. Methods A customized internet search tool (Market Review Tool, MRT) was used by the College of Chiropractors of British Columbia (CCBC), Canada to audit registrants websites and social media activity. The audits extracted words whose use within specific contexts is not permitted under CCBC guidelines. The MRT was first used in October of 2018 to identify words related to specific health conditions. The MRT was again used in December 2019 for words related to pregnancy and most recently in March 2020 for words related to COVID-19. In these three MRT applications, potential cases of word misuse were evaluated by the regulator who then notified the practitioner to comply with existing regulations by a specific date. The MRT was then used on that date to determine compliance. Those found to be non-compliant were referred to the regulator’s inquiry committee. We mapped this process and reported the outcomes with permission of the regulator. Results In September 2018, 250 inappropriate mentions of specific health conditions were detected from approximately 1250 registrants with 2 failing to comply. The second scan for pregnancy related terms of approximately1350 practitioners revealed 83 inappropriate mentions. Following notification, all 83 cases were compliant within the specified timeframe. Regarding COVID-19 related words, 97 inappropriate mentions of the word “immune” were detected from 1350 registrants with 7 cases of non-compliance. Conclusion Internet analytics are an effective way for regulators to monitor internet activity to protect the public from misleading statements. The processes described were effective at bringing about rapid practitioner compliance. Given the increasing volume of internet activity by healthcare professionals, internet analytics are an important addition for health care regulators to protect the public they serve. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource regulation, Chiropractic, Misinformation, Internet analytics Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/s12998-020-00314-9 Source A related resource from which the described resource is derived Chiropractic & Manual Therapies Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Diseases of the musculoskeletal system, Chiropractic https://www.socictopen.socict.org/files/original/dc24be77229a9ac785ce85c8781329f6.pdf 2920bd457ab3382ff987e7fb8b99b705 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The Role of Lipid Metabolism in COVID-19 Virus Infection and as a Drug Target Creator An entity primarily responsible for making the resource Mohamed Abu-Farha, Jehad Abubaker, Fahd Al Mulla, Thangavel Alphonse Thanaraj, Mohammad G. Qaddoumi, Anwar Hashem Description An account of the resource The current Coronavirus disease 2019 or COVID-19 pandemic has infected over two million people and resulted in the death of over one hundred thousand people at the time of writing this review. The disease is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Even though multiple vaccines and treatments are under development so far, the disease is only slowing down under extreme social distancing measures that are difficult to maintain. SARS-COV-2 is an enveloped virus that is surrounded by a lipid bilayer. Lipids are fundamental cell components that play various biological roles ranging from being a structural building block to a signaling molecule as well as a central energy store. The role lipids play in viral infection involves the fusion of the viral membrane to the host cell, viral replication, and viral endocytosis and exocytosis. Since lipids play a crucial function in the viral life cycle, we asked whether drugs targeting lipid metabolism, such as statins, can be utilized against SARS-CoV-2 and other viruses. In this review, we discuss the role of lipid metabolism in viral infection as well as the possibility of targeting lipid metabolism to interfere with the viral life cycle. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource endocytosis, sphingolipid, coronavirus, lipid metabolism, SARS-CoV-2, COVID-19 Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/ijms21103544 Source A related resource from which the described resource is derived International Journal of Molecular Sciences Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General), Chemistry https://www.socictopen.socict.org/files/original/06736b2863175c780527157e6cf30ce7.pdf 401b24a3685109034cb87004bc80e0da Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Allo-priming as a universal anti-viral vaccine: protecting elderly from current COVID-19 and any future unknown viral outbreak Creator An entity primarily responsible for making the resource Reuven Or, Michael Har-Noy Description An account of the resource Abstract Background We present the rationale for a novel allo-priming approach to serve the elderly as a universal anti-virus vaccine, as well serving to remodel the aging immune system in order to reverse immunosenescence and inflammaging. This approach has the potential to protect the most vulnerable from disease and provide society an incalculable economic benefit. Allo-priming healthy elderly adults is proposed to provide universal protection from progression of any type of viral infection, including protection against progression of the current outbreak of COVID-19 infection, and any future variants of the causative SARS-CoV-2 virus or the next ‘Disease X’. Allo-priming is an alternative approach for the COVID-19 pandemic that provides a back-up in case vaccination strategies to elicit neutralizing antibody protection fails or fails to protect the vulnerable elderly population. The allo-priming is performed using activated, intentionally mismatched, ex vivo differentiated and expanded living Th1-like cells (AlloStim®) derived from healthy donors currently in clinical use as an experimental cancer vaccine. Multiple intradermal injections of AlloStim® creates a dominate titer of allo-specific Th1/CTL memory cells in circulation, replacing the dominance of exhausted memory cells of the aged immune system. Upon viral encounter, by-stander activation of the allo-specific memory cells causes an immediate release of IFN-ϒ, leading to development of an “anti-viral state”, by-stander activation of innate cellular effector cells and activation of cross-reactive allo-specific CTL. In this manner, the non-specific activation of allo-specific Th1/CTL initiates a cascade of spatial and temporal immune events which act to limit the early viral titer. The release of endogenous heat shock proteins (HSP) and DAMP from lysed viral-infected cells, in the context of IFN-ϒ, creates of conditions for in situ vaccination leading to viral-specific Th1/CTL immunity. These viral-specific Th1/CTL provide sterilizing immunity and memory for protection from disease recurrence, while increasing the pool of Th1/CTL in circulation capable of responding to the next viral encounter. Conclusion Allo-priming has potential to provide universal protection from viral disease and is a strategy to reverse immunosenescence and counter-regulate chronic inflammation (inflammaging). Allo-priming can be used as an adjuvant for anti-viral vaccines and as a counter-measure for unknown biological threats and bio-economic terrorism. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource immunotherapy, cell therapy, vaccine, immunosenescence, Inflammaging, COVID-19 Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/s12967-020-02363-3 Source A related resource from which the described resource is derived Journal of Translational Medicine Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine