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Sublingual immunization with recombinant adenovirus encoding SARS-CoV spike protein induces systemic and mucosal immunity without redirection of the virus to the brain
Abstract Background Sublingual (s.l.) administration of soluble protein antigens, inactivated viruses, or virus-like particles has been shown to induce broad immune responses in mucosal and extra-mucosal tissues. Recombinant replication-defective…
Position: 10259 (25 views)
Human respiratory viral infections: Current status and future prospects of nanotechnology-based approaches for prophylaxis and treatment.
Respiratory viral infections are major cause of highly mortal pandemics. They are impacting socioeconomic development and healthcare system globally. These emerging deadly respiratory viruses develop newer survival strategies to live inside host…
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COVID-19 Is Further Subdivided Into COVIP-19 and COVII-19
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COVID-19 Is Further Subdivided Into COVIP-19 and COVII-19
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Control Measures for Severe Acute Respiratory Syndrome (SARS) in Taiwan
As of April 14, 2003, Taiwan had had 23 probable cases of severe acute respiratory syndrome (SARS), all imported. Taiwan isolated these first 23 patients with probable SARS in negative-pressure rooms; extensive personal protective equipment was used…
Position: 8734 (27 views)
SARS Coronavirus Papain-Like Protease Inhibits the TLR7 Signaling Pathway through Removing Lys63-Linked Polyubiquitination of TRAF3 and TRAF6
Severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLPro) reportedly inhibits the production of type I interferons (IFNs) and pro-inflammatory cytokines in Toll-like receptor 3 (TLR3) and retinoic acid-inducible gene 1…
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Highlight of Immune Pathogenic Response and Hematopathologic Effect in SARS-CoV, MERS-CoV, and SARS-Cov-2 Infection
A sudden outbreak of COVID-19 caused by a novel coronavirus, SARS-CoV-2, in Wuhan, China in December 2019 quickly grew into a global pandemic, putting at risk not only the global healthcare system, but also the world economy. As the disease continues…
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Comparison of the Characteristics and Outcomes of Coronavirus Disease 2019 in Different Types of Family Infections in Taiwan.
There were some family infections of coronavirus disease 2019 (COVID-19) in Taiwan to date. This study aimed to investigate the clinical characteristics and outcomes of different types of family infections with COVID-19 and to share Taiwan's…
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Management of Irrational Self-Purchase of Hydroxychloroquine During the COVID-19 Pandemic: Experiences From the Largest Healthcare System in Taiwan.
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Magnetic Nanotrap Particles Preserve the Stability of Venezuelan Equine Encephalitis Virus in Blood for Laboratory Detection
Most of the modern techniques used for identification of viral-induced disease are based on identification of viral antigens and/or nucleic acids in patient's blood. Diagnosis in the field or in remote locations can be challenging and alternatively…
Position: 20380 (12 views)