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                <text>Excess Ascorbate is a Chemical Stress Agent against Proteins and Cells</text>
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                <text>Radu Silaghi-Dumitrescu, Augustin C. Mot, Emese Gál, Eva Fischer Fodor, Florina Scurtu, Alina Matei, Maria Lehene, Niculina  D. Hădade</text>
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                <text>Excess ascorbate (as expected in intravenous treatment proposed for COVID-19 management, for example) oxidizes and/or degrades hemoglobin and albumin, as evidenced by UV-vis spectroscopy, gel electrophoresis, and mass spectrometry. It also degrades hemoglobin in intact blood or in isolated erythrocytes. The survival rates and metabolic activities of several leukocyte subsets implicated in the antiviral cellular immune response are also affected. Excess ascorbate is thus an unselective biological stress agent.</text>
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                <text>DOI: 10.3390/ph13060107</text>
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                <text>Potential therapeutic effect of Qingwen Baidu Decoction against Corona Virus Disease 2019: a mini review</text>
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                <text>Min Wang, Yan-Ling Zhao, Haotian Li, Jianxia Wen, Xuelin Zhou, Honghong Liu, Shizhang Wei, Rui-Lin Wang, Yuling Tong, Manyi Jing</text>
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                <text>Abstract The Corona Virus Disease 2019 (COVID-19) is an acute respiratory infectious disease. At present, COVID-19 has no specific therapeutic drugs, and the main clinical treatment is symptomatic treatment and control of complications. On March 5, 2020, the National Health Commission of the People’s Republic of China issued the Guidelines for the Diagnosis and Treatment of Novel Coronavirus (2019-nCoV) Infection (Trial Version 7), which integrated traditional Chinese medicine (TCM) into the treatment of COVID-19. The purpose of this study is to summarize recent studies on the clinic application, pharmacological action, chemical substances and mechanism of Qingwen Baidu Decoction (QBD) on the treatment of various diseases. The results suggested that QBD has multiple pharmacological effects such as anti-inflammation, antiviral, antibacterial, immunomodulatory, antipyretic and so on. It has been used in the treatment of sepsis, epidemic hemorrhagic fever, epidemic cerebrospinal meningitis, infantile pneumonia, sepsis-related encephalopathy, epidemic encephalitis B and other diseases. In addition, this study attempts to explore the possible mechanism of QBD in the prevention and treatment of COVID-19. Through the analysis of the chemical substances, pharmacological action and mechanism of QBD, this paper will provide a reference theoretical basis for the prevention and treatment of COVID-19 by QBD.</text>
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                <text>functional characteristics, theoretical basis, corona virus disease 2019, Qinwen Baidu Decoction</text>
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                <text>DOI: 10.1186/s13020-020-00332-y</text>
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                <text>Christian Meyer, Pierre Pasquier, Khaldoun Kuteifan, Odile Theissen, Jacques Escarment</text>
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                <text>DOI: 10.1186/s13613-020-00677-5</text>
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                <text>Annals of Intensive Care</text>
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                <text>Medical emergencies. Critical care. Intensive care. First aid</text>
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              <name>Title</name>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Knowledge and Information Sources About COVID-19 Among University Students in Jordan: A Cross-Sectional Study</text>
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                <text>AMIN N. OLAIMAT, RICHARD A. HOLLEY, Iman Aolymat, Hafiz M. Shahbaz</text>
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                <text>Background: Coronavirus disease 2019 (COVID-19) has rapidly spread worldwide, and it was officially declared to be a pandemic by the World Health Organization (WHO) on March 11, 2020. Most countries over the entire globe have reported some COVID-19 cases. The current study aimed to assess student knowledge about COVID-19 at different Jordanian universities and determine where they sourced their information.Methods:A cross-sectional study was conducted among 2,083 undergraduate or postgraduate students from different governmental and private universities during the initial stage of the disease in Jordan (March 19–21, 2020) using a validated, structured, self-administered, online questionnaire. The survey was structured to assess their knowledge about viral sources, incubation period, mortality rate, transmission, symptoms and complications as well as the source of information about COVID-19.Results:Overall, 56.5% of the respondents showed good knowledge and almost 40.5% showed moderate knowledge. On the other hand, 3.0% of the participants showed poor knowledge about COVID-19. The average knowledge score of students was 80.1%, which is considered to be within the scale of good knowledge. Both the college of study and educational level significantly (P &amp;lt; 0.05) associated with student knowledge. Students who majored in medical sciences showed the highest mean score of 82.8%, with 69.0% displaying a good knowledge level. Postgraduate students had significantly higher knowledge scores compared to undergraduate students. The majority of students used the internet, social media and mass media as sources of information about COVID-19. Scientific websites and articles were used more commonly by medical and postgraduate students.Conclusions:The COVID-19 pandemic is a major challenge to the health of the world population; therefore, these results assessing students' knowledge provide an important baseline for planning required educational interventions such as contact tracing and self-quarantine. These results may also help public health authorities by engaging communities in implementation of protective health measures, including positive hygienic practices such as hand washing to reduce the risk of COVID-19.</text>
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                <text>DOI: 10.3389/fpubh.2020.00254</text>
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                <text>Frontiers in Public Health</text>
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                <text>Frontiers Media S.A.</text>
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                <text>Public aspects of medicine</text>
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                <text>Medical Students and COVID-19: Knowledge, Attitudes, and Precautionary Measures. A Descriptive Study From Jordan</text>
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                <text>Tareq Saleh, Khalid A Kheirallah, Nail Obeidat, Sarah Bloukh, Ashraf I. Khasawneh, Anas Abu Humeidan, Jomana W. Alsulaiman, Mohannad Ramadan, Tariq N. Al-Shatanawi, Hasan H. Awad, Waleed Y. Hijazi, Kinda R. Al-Kammash</text>
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                <text>The recent coronavirus disease (COVID-19) pandemic is associated with increasing morbidity and mortality and has impacted the lives of the global populations. Human behavior and knowledge assessment during the crisis are critical in the overall efforts to contain the outbreak. To assess knowledge, attitude, perceptions, and precautionary measures toward COVID-19 among a sample of medical students in Jordan. This is a cross-sectional descriptive study conducted between the 16th and 19th of March 2020. Participants were students enrolled in different levels of study at the six medical schools in Jordan. An online questionnaire which was posted on online platforms was used. The questionnaire consisted of four main sections: socio-demographics, sources of information, knowledge attitudes, and precautionary measures regarding COVID-19. Medical students used mostly social media (83.4%) and online search engines (84.8%) as their preferred source of information on COVID-19 and relied less on medical search engines (64.1%). Most students believed that hand shaking (93.7%), kissing (94.7%), exposure to contaminated surfaces (97.4%), and droplet inhalation (91.0%) are the primary mode of transmission but were indecisive regarding airborne transmission with only 41.8% in support. Participants also reported that elderly with chronic illnesses are the most susceptible group for the coronavirus infection (95.0%). As a response to the COVID-19 pandemic more than 80.0% of study participants adopted social isolation strategies, regular hand washing, and enhanced personal hygiene measures as their first line of defense against the virus. In conclusion, Jordanian medical students showed expected level of knowledge about the COVID-19 virus and implemented proper strategies to prevent its spread.</text>
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                <text>2020</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>Attitude, Knowledge, stigma, Medical students, precautionary measures, COVID-19</text>
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                <text>DOI: 10.3389/fpubh.2020.00253</text>
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                <text>Frontiers in Public Health</text>
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            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="26179">
                <text>Frontiers Media S.A.</text>
              </elementText>
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                  <text>Dominio científico: Coronavirus</text>
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          <element elementId="50">
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                <text>SARS-CoV-2, “common cold” coronaviruses’ cross-reactivity and “herd immunity”: The razor of Ockham (1285-1347)?</text>
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            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="26182">
                <text>Nicola Petrosillo</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>After the rapid spread of coronavirus-19 infectious disease (COVID-19) worldwide between February and April 2020, with a total of 5,267,419 confirmed cases and 341,155 deaths as of May 25, 2020, in the last weeks we are observing a decrease in new infections in European countries, and the confirmed cases are not as severe as in the past, so much so that the number of patients transferred to intensive care for the worsening of the systemic and pulmonary disease is dramatically decreasing [...]</text>
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                <text>2020</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="26185">
                <text>herd immunity, common cold, SARS-CoV-2, COVID-19</text>
              </elementText>
            </elementTextContainer>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="26186">
                <text>DOI: 10.4081/idr.2020.8647</text>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="26187">
                <text>Infectious Disease Reports</text>
              </elementText>
            </elementTextContainer>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
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                <text>PAGEPress Publications</text>
              </elementText>
            </elementTextContainer>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="26189">
                <text>Other systems of medicine</text>
              </elementText>
            </elementTextContainer>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="1">
                  <text>Coronavirus</text>
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              </elementTextContainer>
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              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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              </elementTextContainer>
            </element>
          </elementContainer>
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      </elementSetContainer>
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    <itemType itemTypeId="1">
      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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    <elementSetContainer>
      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="26190">
                <text>Forecasting COVID-19 in Morocco</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="26191">
                <text>Mohammed Layelmam, Y. Ahmed Laaziz, Said Benchelha, Yahya Diyer, Sarra Rarhibou</text>
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            </elementTextContainer>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="26192">
                <text>The COVID-19 has become a public health emergency of international concern. As of April 26, 2020, this pandemic has caused in Morocco more than 4065 confirmed infections and more than 161 reported deaths. To mitigate this epidemic threat and act quickly, it is very important to monitor and analyze changing trends and predict what might happen in the future. The main objective of this paper is to develop a successful prediction. We used in this study at the end of each week the TBATS model to forecast confirmed cases. This model is calculated on the basis of the daily historical data. From the results obtained we can conclude that the predictions obtained are close to reality and for the peak of this epidemic is not yet identified. The obtained results shows that this epidemics will continue to grow. For our forecast from 04/27/2020 to 05/03/2020 we estimate that the number of affected cases will achieve 4367 cases.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="26193">
                <text>2020</text>
              </elementText>
            </elementTextContainer>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="26194">
                <text>forecasting, coronavirus, Morocco, COVID-19, TBATS</text>
              </elementText>
            </elementTextContainer>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="26195">
                <text>DOI: 10.5799/jcei/8264</text>
              </elementText>
            </elementTextContainer>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="26196">
                <text>Journal of Clinical and Experimental Investigations</text>
              </elementText>
            </elementTextContainer>
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          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="26197">
                <text>Association of Health Investigations</text>
              </elementText>
            </elementTextContainer>
          </element>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="26198">
                <text>Medicine</text>
              </elementText>
            </elementTextContainer>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="1">
                  <text>Coronavirus</text>
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              </elementTextContainer>
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              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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              </elementTextContainer>
            </element>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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    <elementSetContainer>
      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="26199">
                <text>An Online Observational Study of Patients With Olfactory and Gustory Alterations Secondary to SARS-CoV-2 Infection</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="26200">
                <text>Beatriz Parejo-Carbonell, Jordi A. Matias-Guiu, Jorge Matias-Guiu, Jose-Miguel Lainez, Jesús Porta-Etessam, David Ezpeleta, Patricia Gómez-Iglesias, Teresa Montalvo, Adrián Valls-Carbó, Vicente Gajate, Nuria González-García</text>
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            <description>An account of the resource</description>
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                <text>Introduction: Since the beginning of the Covid-19 epidemic produced by SARS2-Cov virus, olfactory alterations have been observed at a greater frequency than in other coronavirus epidemics. While olfactory alterations may be observed in patients with rhinovirus, influenza virus, or parainfluenza virus infection, they are typically explained by nasal obstruction with mucus or direct epithelial damage; in the case of SARS-CoV-2, olfactory alterations may present without nasal congestion with mucus. We performed a study of patients presenting olfactory/gustatory alterations in the context of SARS-CoV-2 infection in order to contribute to the understanding of this phenomenon.Material and Methods: We performed a descriptive, cross-sectional, observational study of the clinical characteristics of olfactory/gustatory alterations using a self-administered, anonymous online questionnaire.Results: A total of 909 patients with SARS-CoV-2 infection and olfactory/gustatory alterations responded to the questionnaire in the 4-day data collection period; 824 cases (90.65%) reported simultaneous olfactory and gustatory involvement. Patients' responses to the questionnaire revealed ageusia (581, 64.1% of respondents), hypogeusia (256, 28.2%), dysgeusia (22, 2.4%), anosmia (752 82.8%), hyposmia (142, 15.6%), and dysosmia (8, 0.9%). Fifty-four percent (489) did not report concomitant nasal congestion or mucus.Conclusion: Olfactory alterations are frequent in patients with SARS-CoV-2 infection and is only associated with nasal congestion in half of the cases.</text>
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                <text>2020</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>coronavirus, anosmia, neurological, SARS-CoV-2, COVID-19, olfactory alterations</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="26204">
                <text>DOI: 10.3389/fpubh.2020.00243</text>
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            </elementTextContainer>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="26205">
                <text>Frontiers in Public Health</text>
              </elementText>
            </elementTextContainer>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="26206">
                <text>Frontiers Media S.A.</text>
              </elementText>
            </elementTextContainer>
          </element>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Public aspects of medicine</text>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="1">
                  <text>Coronavirus</text>
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              </elementTextContainer>
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              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Schooling Beyond COVID-19: An Unevenly Distributed Future</text>
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          <element elementId="39">
            <name>Creator</name>
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              <elementText elementTextId="26209">
                <text>Gavin T. L. Brown</text>
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            <description>An account of the resource</description>
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              <elementText elementTextId="26210">
                <text>The COVID-19 pandemic crisis has had a major impact on how schooling is done. With schools closed, teaching, and learning continue dependent on information and communication technologies (ICT). To the degree that this has been a success, there is the possibility that post-pandemic societies might choose to de-school, switching to online teaching and learning only. In this perspective piece, I describe two major risks if that future were to be embraced; that is, lack of equitable access and dehumanization. My argument is that these futures already exist in pockets around the globe and we can use those experiences to evaluate those options. I suggest instead that the post-pandemic period gives us an opportunity to re-imagine what schools and schooling are for and advocate for a re-schooled society in which our investment in schools builds and develops society.</text>
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                <text>2020</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="26212">
                <text>access, Schooling, future, dehumanization, deschooling, reschooling</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="26213">
                <text>DOI: 10.3389/feduc.2020.00082</text>
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            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="26214">
                <text>Frontiers in Education</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="26215">
                <text>Frontiers Media S.A.</text>
              </elementText>
            </elementTextContainer>
          </element>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="26216">
                <text>Education (General)</text>
              </elementText>
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                <text>Armando  Santoro, Elena Lorenzi, Pasquale Persico, Matteo Simonelli, Monica Bertossi, Angelo Dipasquale</text>
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                <text>cancer, clinical trial, SARS-CoV-2, covi-19, Phase I (drug development)</text>
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                <text>Frontiers in Oncology</text>
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                <text>Frontiers Media S.A.</text>
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                <text>Neoplasms. Tumors. Oncology. Including cancer and carcinogens</text>
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