289 10 20655 https://www.socictopen.socict.org/files/original/943e277eedbe32bf4775aaea919e0e87.pdf acc70b7da24749bd8da83b956d05a0ea Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource FLUed: A Novel Four-Layer Model for Simulating Epidemic Dynamics and Assessing Intervention Policies Creator An entity primarily responsible for making the resource Tzai-Hung Wen, Chung-Yuan Huang, Yu-Shiuan Tsai Description An account of the resource From the 2003 severe acute respiratory syndrome (SARS) epidemic, to the 2009 swine-origin influenza A (H1N1) pandemic, to the projected highly pathogenic avian influenza A event, emerging infectious diseases highlight the importance of computational epidemiology to assess potential intervention policies. Hence, an important and timely research goal is a general-purpose and extendable simulation model that integrates two major epidemiological factors—age group and population movement—and substantial amounts of demographic, geographic, and epidemiologic data. In this paper, we describe a model that we have named FLUed for Four-layer Universal Epidemic Dynamics that integrates complex daily commuting network data into multiple age-structured compartmental models. FLUed has four contact structures for simulating the epidemic dynamics of emerging infectious diseases, assessing the potential efficacies of various intervention policies, and identifying the potential impacts of spatial-temporal epidemic trends on specific populations. We used data from the seasonal influenza A and 2009 swine-origin influenza A (H1N1) epidemics to validate model reliability and suitability and to assess the potential impacts of intervention policies and variation in initial outbreak areas for novel/seasonal influenza A in Taiwan. We believe that the FLUed model represents an effective tool for public health agencies responsible for initiating early responses to potential pandemics. Date A point or period of time associated with an event in the lifecycle of the resource 2013 Identifier An unambiguous reference to the resource within a given context DOI: 10.1155/2013/325816 Source A related resource from which the described resource is derived Journal of Applied Mathematics Publisher An entity responsible for making the resource available Hindawi Limited Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Mathematics https://www.socictopen.socict.org/files/original/bcff172ccc5e14ba02a241f2053fb3dc.pdf 7735cffc99ff5413c251c19ba416db4d Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Transmissible Gastroenteritis Virus Papain-Like Protease 1 Antagonizes Production of Interferon-β through Its Deubiquitinase Activity Creator An entity primarily responsible for making the resource Jin Tian, Liandong Qu, Zhijie Li, Qian Jiang, Hongtao Kang, Dafei Liu, Xiaoliang Hu, Dongchun Guo, Jiasen Liu, Juanjuan Qu Description An account of the resource Coronaviruses (CoVs), such as human coronavirus NL63 (HCoV-NL63), severe acute respiratory syndrome CoV (SARS-CoV), murine hepatitis virus (MHV), porcine epidemic diarrhea virus (PEDV), and Middle East Respiratory Syndrome Coronavirus (MERS-CoV), encode papain-like (PL) proteases that inhibit Sendai virus- (SeV-) induced interferon (IFN-β) production. Recently, the crystal structure of transmissible gastroenteritis virus (TGEV) PL1 has been solved, which was similar to that of SARS-CoV PL2pro, which may antagonize host innate immunity. However, very little is known about whether TGEV PL1 can antagonize host innate immune response. Here, we presented evidence that TGEV PL1 encoded by the replicase gene could suppress the IFN-β expression and inhibit the nuclear translocation of interferon regulatory factor 3 (IRF3). The ability to antagonize IFN-β production was dependent on the intact catalytic activity of PL1. Furthermore, TGEV PL1 exerted deubiquitinase (DUB) activity which strongly inhibited the retinoic acid-induced gene I- (RIG-1-) and stimulator of interferon gene- (STING-) dependent IFN expression. Our data collectively suggest that TGEV PL1 can inhibit the IFN-β expression and interfere with RIG-1- and STING-mediated signaling through a viral DUB activity. Our study has yielded strong evidence for the TGEV PL1 mechanisms that counteract the host innate immunity. Date A point or period of time associated with an event in the lifecycle of the resource 2017 Identifier An unambiguous reference to the resource within a given context DOI: 10.1155/2017/7089091 Source A related resource from which the described resource is derived BioMed Research International Publisher An entity responsible for making the resource available Hindawi Limited Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine https://www.socictopen.socict.org/files/original/88ff5b05b0500274414b131ecf190db6.pdf 96371277f03a72f428be703f6c993bc1 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Antibody response and protection of inactivated-local isolate vaccine for infectious bronchitis in laying chicken Creator An entity primarily responsible for making the resource Risa Indriani, Darminto Description An account of the resource Infectious bronchitis (IB) is an acute highly contagious viral respiratory disease of poultry caused by Coronavirus. IBV infection consists of many serotypes and can only be controlled by vaccination. An effective IB vaccine should be prepared from local isolates, due to the antigenic variation among serotypes. The aims of this research were to develop inactivated IB vaccine derived from IBV local isolate and to determine the efficacy of that vaccine in layer flocks. Five layer chicken groups were used in this experiments, group I was vaccinated with commercial IBV live vaccine thrice, group II was vaccinated with commercial IBV live vaccine once and repeated with inactivated local IBV isolate twice, group III was vaccinated with commercial IBV live vaccine once and repeated with commercial inactivated twice, group IV was vaccinated with IBV live vaccine once, and group V was not vaccinated. After the chickens reached at a stable egg production they were challenged with IBV local isolates. Antibody responses were examined by means of haemagglutination hibitition (HI) test and HI titres were expressed as log2 of the reciprocal of the highest dilution of serum causing inhibition of a log2 HA titre of 2. The mean titres of antibody responses of chicken in group I, II, III, IV, and V was 4.9 ± 0.87, 6.8 ± 0.97, 7.7 ± 0.46, 2.9 ± 0.94, and 2.0 ± 1.67 respectively. The levels of protection against challenges were determined by viral isolation, this in group I, II, III, IV, and V was 63, 73, 60, 50, and 0% respectively. Clinical symptom of egg quality was slightly reduced in group I, IV, and V and it were unchanged in group II and III. Group II gave better in number of egg production than the other groups. The results indicated that the IBV inactivated localisolate vaccine gave high titres of antibody and higher protection rates than that of commercial IBV inactivated vaccine. Inaddition, IBV local isolate vaccinated group prevented from declining egg production after challenged with IBV local isolate. Date A point or period of time associated with an event in the lifecycle of the resource 2001 Subject The topic of the resource vaccine, Infectious Bronchitis, Layer, antibody titre, challenge virus Identifier An unambiguous reference to the resource within a given context DOI: Source A related resource from which the described resource is derived Jurnal Ilmu Ternak dan Veteriner Publisher An entity responsible for making the resource available Pusat Penelitian dan Pengembangan Peternakan Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Agriculture, Animal culture https://www.socictopen.socict.org/files/original/6ff9aea678e0308e0e7945e56ce1c8c6.pdf 36d6f5a3e5e8bb566ac79800eb87289e Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Viral aetiology of wheezing in children under five Creator An entity primarily responsible for making the resource Bhagirathi Dwibedi, Prithi Sureka Mummidi, Radha Tripathy, Amarendra Mahapatra, Suryakanta Baraha Description An account of the resource Background & objectives: Wheezing is a common problem in children under five with acute respiratory infections (ARIs). Viruses are known to be responsible for a considerable proportion of ARIs in children. This study was undertaken to know the viral aetiology of wheezing among the children less than five years of age, admitted to a tertiary care hospital in eastern India. Methods: Seventy five children, under the age of five years admitted with wheezing, were included in the study. Throat and nasal swabs were collected, and real-time multiplex polymerase chain reaction (PCR) assay was used to screen for influenza 1 and 2, respiratory syncytial virus (RSV), parainfluenza virus (PIV) 1, 2, 3 and 4, rhinovirus, human meta-pneumovirus, bocavirus (HBoV), Coronavirus, adenovirus, Enterovirus and Parechovirus. Results: The total viral detection rate was 28.57 per cent. Viral RNA markers were detected from children diagnosed to be having pneumonia (3 cases), bronchiolitis (9 cases), episodic wheeze (2 cases) and multitrigger wheeze (6 cases). RSV was the most common virus (35%) followed by PIV1, 2 and 3 (20%), HBoV (10%) and rhinovirus (5%). However, mixed infection was observed in 30 per cent of cases. Interpretation & conclusions: The study reported the presence of respiratory viral agents in 28.57 per cent of children with wheezing; RSV and PIV were most common, accounting to 55 per cent of the total cases. Mixed infection was reported in 30 per cent of cases. Seasonal variation in the occurrence of these viruses was also noted. Further studies need to be done with a large sample and longer follow up period to verify these findings. Date A point or period of time associated with an event in the lifecycle of the resource 2017 Subject The topic of the resource Asthma - bronchiolitis - child - incidence - India - multiplex polymerase chain reaction Identifier An unambiguous reference to the resource within a given context DOI: 10.4103/ijmr.IJMR_840_15 Source A related resource from which the described resource is derived Indian Journal of Medical Research Publisher An entity responsible for making the resource available Wolters Kluwer Medknow Publications Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine https://www.socictopen.socict.org/files/original/6498f7983c8a5b00f3c970c61f492a97.pdf 54d8c0af96879a1f366dc9ec031a40ff Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Development of inactivated-local isolate vaccine for infectious bronchitis Creator An entity primarily responsible for making the resource Darminto Description An account of the resource Infectious bronchitis (IB) is an acute highly contagious viral respiratory disease of poultry caused by coronavirus. The disease causes high mortality in young chicks, reduce body weight gain in broilers and remarkable drop in egg production. IB can only be controlled by vaccination, but due to the antigenic variation among serotypes of IB viruses, the effective IB vaccine should be prepared from local isolates. The aim of this research is to develop inactivated IB vaccine derived from local IB isolates. Local isolates of IB viruses designated as I-37, I-269 and PTS-III were propagated respectively in specific pathogen free (SPF) chicken eggs, the viruses then were inactivated by formaline at final concentration of 1:1,000. Subsequently, the inactivated viruses were mixed and emulsified in oil emulsion adjuvant with sorbitant mono-oleic as an emulsifier. The vaccine then was tested for its safety, potency and efficacy in broiler chickens. Birds inoculated twice with a two-week interval by inactivated vaccine did not show any adverse reaction, either systemic or local reaction. The inoculated birds developed antibody responses with high titre, while antibody of the control birds remain negative. In addition, efficacy test which was conducted in broilers demonstrated that birds vaccinated by live-commercial vaccine and boosted three weeks later by Balitvet inactivated vaccine showed high level of antibody production which provided high level of protection against challenged virus (76% against I-37, 92% against I-269 and 68% against PTS-III challenge viruses). From this study, it can be concluded that inactivated local IB vaccine is considered to be safe, potent and efficacious. The vaccine stimulates high titre of antibody responses, which provide high level of protection against challenged viruses. Date A point or period of time associated with an event in the lifecycle of the resource 1999 Subject The topic of the resource Antibody, broiler chicken, virus, Infectious Bronchitis, inactivated vaccine Identifier An unambiguous reference to the resource within a given context DOI: Source A related resource from which the described resource is derived Jurnal Ilmu Ternak dan Veteriner Publisher An entity responsible for making the resource available Pusat Penelitian dan Pengembangan Peternakan Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Agriculture, Animal culture https://www.socictopen.socict.org/files/original/40f63e247f3ea9c03898a8902add64f0.pdf d0dc3821c217953008a065a43a49e1a1 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The Hazards of a Practicing Respirologist Creator An entity primarily responsible for making the resource Dennis Bowie Description An account of the resource The advent of severe acute respiratory syndrome (SARS) in March 2003 reminded us that health care workers are at risk of being stricken with the very diseases that we are treating. Health care workers accounted for 65% of the SARS cases in Canada (1) and represented at least one-quarter of the cases in Hong Kong (2). Because SARS presents as a severe pneumonia and is diagnosed by certain epidemiological characteristics, history and a positive chest x-ray, respirologists are often the first-line consultants to see patients with an unusual pneumonia. If we are lucky, there may be telling clues to the diagnosis such as a travel history or contact with other cases. However, in the absence of these clues, it behooves the medical profession to use universal precautions. Date A point or period of time associated with an event in the lifecycle of the resource 2004 Identifier An unambiguous reference to the resource within a given context DOI: 10.1155/2004/523265 Source A related resource from which the described resource is derived Canadian Respiratory Journal Publisher An entity responsible for making the resource available Hindawi Limited Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Diseases of the respiratory system https://www.socictopen.socict.org/files/original/1f150fa94942228d9f3bc8ce7d51e51b.pdf 36d6f5a3e5e8bb566ac79800eb87289e Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Respiratory viruses in returning Hajj & Umrah pilgrims with acute respiratory illness in 2014-2015 Creator An entity primarily responsible for making the resource Anand Krishnan, Parvaiz A Koul, Hyder Mir, Varsha Potdar, Mandeep S Chadha, Marc-Alain Widdowson, Siddhartha Saha, Renu B Lal Description An account of the resource Background & objectives: Respiratory tract infections are common among Hajj and Umrah pilgrims which pose a public health risk of spread of respiratory infections. Influenza has been reported from Indian Hajj and Umrah returning pilgrims, but data on other respiratory pathogens are sparse in India. Here we report the presence of common respiratory viral pathogens in returning Hajj and Umrah pilgrims suffering from acute respiratory illness (ARI) in 2014-2015. Methods: Respiratory specimens (nasopharyngeal and throat swabs) were collected from 300 consenting pilgrims with ARI in the past one week and tested for influenza and Middle East Respiratory Syndrome coronavirus (MERS-CoV) and other respiratory viruses using in-house standardized quantitative real-time reverse-transcription polymerase chain reaction. Clinical features among the pathogen positive and negative patients were compared. The patients received symptomatic treatment and antivirals where appropriate and were followed telephonically to collect data on illness outcome. Results: Ninety seven (32.3%) of the 300 participants were tested positive for any virus, most common being influenza viruses (n=33, 11%). Other respiratory viruses that were detected included human coronaviruses [n=26, 8.7%; OC43 (n=19, 6.3%) and C229E (n=7, 2.3%)], rhinovirus (n=20, 6%), adenoviruses (n=8, 2.6%), parainfluenza viruses (n=7, 2.3%), respiratory syncytial virus (n=3, 1%) and bocaviruses (n=2, 0.6%). Clinical features observed in pathogen positive and pathogen negative patients did not differ significantly. Eighteen influenza positive patients were treated with oseltamivir. Interpretation & conclusions: Pilgrims returning from mass gatherings are often afflicted with respiratory pathogens with a potential to facilitate transmission of respiratory pathogens across international borders. The study reinforces the need for better infection prevention and control measures such as vaccination, health education on cough etiquette and hand hygiene. Date A point or period of time associated with an event in the lifecycle of the resource 2018 Subject The topic of the resource Acute respiratory infection - coronavirus - Hajj pilgrims - influenza virus - respiratory syncytial virus - respiratory viruses Identifier An unambiguous reference to the resource within a given context DOI: 10.4103/ijmr.IJMR_890_17 Source A related resource from which the described resource is derived Indian Journal of Medical Research Publisher An entity responsible for making the resource available Wolters Kluwer Medknow Publications Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine https://www.socictopen.socict.org/files/original/bf24d4db4a344def4150dfb751933088.pdf c2fceb2e2243b5f89457ab56f5bb57e9 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The Effects of Temperature and Relative Humidity on the Viability of the SARS Coronavirus Creator An entity primarily responsible for making the resource K. H. Chan, K. Y. Yuen, JS Malik Peiris, S. Y. Lam, L. L. M. Poon, W. H. Seto Description An account of the resource The main route of transmission of SARS CoV infection is presumed to be respiratory droplets. However the virus is also detectable in other body fluids and excreta. The stability of the virus at different temperatures and relative humidity on smooth surfaces were studied. The dried virus on smooth surfaces retained its viability for over 5 days at temperatures of 22–25°C and relative humidity of 40–50%, that is, typical air-conditioned environments. However, virus viability was rapidly lost (>3 log10) at higher temperatures and higher relative humidity (e.g., 38°C, and relative humidity of >95%). The better stability of SARS coronavirus at low temperature and low humidity environment may facilitate its transmission in community in subtropical area (such as Hong Kong) during the spring and in air-conditioned environments. It may also explain why some Asian countries in tropical area (such as Malaysia, Indonesia or Thailand) with high temperature and high relative humidity environment did not have major community outbreaks of SARS. Date A point or period of time associated with an event in the lifecycle of the resource 2011 Identifier An unambiguous reference to the resource within a given context DOI: 10.1155/2011/734690 Source A related resource from which the described resource is derived Advances in Virology Publisher An entity responsible for making the resource available Hindawi Limited Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology https://www.socictopen.socict.org/files/original/9884c36bd2102179a9cffa958024c24b.pdf 1e63259b18643e99f2ce1fc243ba533e Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Innovation and Challenges in Funding Rapid Research Responses to Emerging Infectious Diseases: Lessons Learned from the Outbreak of Severe Acute Respiratory Syndrome Creator An entity primarily responsible for making the resource Bhagirath Singh Description An account of the resource Although the local public health response to the severe acute respiratory syndrome outbreak in Canada was critical to the diagnosis, management and treatment of patients, such a rapid research response required a national effort to engage the research and stakeholder communities. The Canadian research effort, coordinated through the Institute of Infection and Immunity of the Canadian Institutes of Health Research and the Michael Smith Foundation for Health Research, has provided insight into the mechanisms required to ensure the rapid development of strategical initiatives in response to emerging infectious diseases. It has also provided a rational basis to set up a national network to be engaged if needed in the future. Date A point or period of time associated with an event in the lifecycle of the resource 2004 Identifier An unambiguous reference to the resource within a given context DOI: 10.1155/2004/925872 Source A related resource from which the described resource is derived Canadian Journal of Infectious Diseases and Medical Microbiology Publisher An entity responsible for making the resource available Hindawi Limited Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Microbiology https://www.socictopen.socict.org/files/original/2c2be6bff5b2706d9b18a82446a90968.pdf f03680a999e3837d9d73ba8c3415c9ee Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Analysis of Spatiotemporal Characteristics of Pandemic SARS Spread in Mainland China Creator An entity primarily responsible for making the resource Chunxiang Cao, Wei Chen, Jian Zhao, Jinfeng Wang, Sheng Zheng, Wu-Chun Cao Description An account of the resource Severe acute respiratory syndrome (SARS) is one of the most severe emerging infectious diseases of the 21st century so far. SARS caused a pandemic that spread throughout mainland China for 7 months, infecting 5318 persons in 194 administrative regions. Using detailed mainland China epidemiological data, we study spatiotemporal aspects of this person-to-person contagious disease and simulate its spatiotemporal transmission dynamics via the Bayesian Maximum Entropy (BME) method. The BME reveals that SARS outbreaks show autocorrelation within certain spatial and temporal distances. We use BME to fit a theoretical covariance model that has a sine hole spatial component and exponential temporal component and obtain the weights of geographical and temporal autocorrelation factors. Using the covariance model, SARS dynamics were estimated and simulated under the most probable conditions. Our study suggests that SARS transmission varies in its epidemiological characteristics and SARS outbreak distributions exhibit palpable clusters on both spatial and temporal scales. In addition, the BME modelling demonstrates that SARS transmission features are affected by spatial heterogeneity, so we analyze potential causes. This may benefit epidemiological control of pandemic infectious diseases. Date A point or period of time associated with an event in the lifecycle of the resource 2016 Identifier An unambiguous reference to the resource within a given context DOI: 10.1155/2016/7247983 Source A related resource from which the described resource is derived BioMed Research International Publisher An entity responsible for making the resource available Hindawi Limited Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine