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                <text>Carleen Klumpp-Thomas, Heather Kalish, Jennifer Hicks, Jennifer Mehalko, Matthew Drew, Matthew J Memoli, Matthew D Hall, Dominic Esposito, Kaitlyn Sadtler</text>
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                <text>Emergence of a new spike protein variant (D614G) with increased infectivity has prompted many to analyze its role in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. There is concern regarding whether an individual exposed to one variant of a virus will have cross-reactive memory to the second variant. Accordingly, we analyzed the serologic reactivity of both variants, and we found that antibodies from 88 donors from a high-incidence population reacted toward both the original spike and the D614 spike variant. These data suggest that patients who are exposed to either variant have cross-responsive humoral immunity. This represents an important finding both for SARS-CoV-2 disease biology and for therapeutics.</text>
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                <text>The Journal of infectious diseases</text>
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                <text>Taxonomía de Chaenorhinum rubrifolium aggr. (Scrophulariaceae) en el área mediterránea occidental</text>
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                <text>Carles Benedí González</text>
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                <text>Se realiza un estudio taxonómico de 9 taxones (seis específicos) pertenecientes al agregado de Chaenorhinum rubrifolium (Antirrhineae-Scrophularioceae) en el mediterráneo occidental, aportando una clave con nuevos caracteres diagnósticos. Para cada taxon se dan el nombre correcto, sinónimos, descripción, corología y ecología, así como comentarios nomenclaturales y relativos a la tipificación. Se proponen dos nuevas combinaciones. Chaenorhinum reyesii (Vicioso &amp; Pau in Pau) Benedí y C. grandiflorum subsp. carthaginense (Pau) Benedí, y se describe una nueva especie del Norte de Africa: C suttonii Benedí&amp; P. Montserrat. Se reivindican la categoría específica de C formenterae Gand. y la combinación C rupestre (Guss.) Maire.</text>
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                <text>1991</text>
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                <text>Scrophulariaceae, angiospermas, chaenorhinum, taxanomía</text>
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                <text>Collectanea Botanica</text>
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                <text>Consejo Superior de Investigaciones Científicas</text>
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                <text>Biology (General), Botany</text>
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                <text>&lt;a href="http://collectaneabotanica.revistas.csic.es/index.php/collectaneabotanica/article/view/106" target="_blank" rel="noreferrer noopener"&gt;http://collectaneabotanica.revistas.csic.es/index.php/collectaneabotanica/article/view/106&lt;/a&gt;</text>
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                <text>GOBERNANZA DEL AGUA Y TERRITORIOS HIDROSOCIALES: DEL ANÁLISIS INSTITUCIONAL A LA ECOLOGÍA POLÍTICA</text>
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                <text>Carles Sanchis Ibor, Rutgerd Boelens</text>
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            <description>An account of the resource</description>
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                <text>En las últimas décadas han surgido diversos enfoques para dar respuesta a los desafíos que plantea la gestión del agua. Este artículo presenta, de manera introductoria, las principales aproximaciones teóricas desde las cuales se está analizando en la actualidad el manejo y la gobernanza del agua: las corrientes neoinstitucionalistas, la teoría de los recursos comunes y la perspectiva del empoderamiento que se relaciona con la ecología política. La descripción de estos enfoques sirve para contextualizar las distintas aportaciones que se presentan en este monográfico sobre el estudio de los territorios hidrosociales, cuyos principales resultados se exponen sucintamente.</text>
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                <text>2018</text>
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                <text>Ecologia Política, conflictividad hidráulica, gobernanza del agua, neointitucionalismo, recursos comunes, territorios hidrosociales</text>
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                <text>10.7203/CGUV.101.13718</text>
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                <text>Cuadernos de Geografía de la Universitat de València</text>
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                <text>Universitat de València, Departament de Geografia</text>
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                <text>Geography (General)</text>
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                <text>&lt;a href="https://ojs.uv.es/index.php/CGUV/article/view/13718" target="_blank" rel="noreferrer noopener"&gt;https://ojs.uv.es/index.php/CGUV/article/view/13718&lt;/a&gt;</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>UAV, Digital Processing and Vectorization Techniques Applied to Building Condition Assessment and Follow-up</text>
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                <text>Carles Serrat*, Sebastian Banaszek, Anna Cellmer, Vicenç Gibert, Anna Banaszek</text>
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                <text>The aim of the paper is to explain the basic principles of carrying out an inventory and follow-up of buildings and their condition assessment, by using the Full Interactive Visualization Method for Building Condition Assessment platform. It is a platform enabling the implementation of construction inventory based on the remote cooperation of many specialists in the field of, among others: building construction, architecture, civil engineering, photogrammetry, CAD, UAV. This type of cooperation is of particular importance especially in the context of the current epidemiological situation related to COVID-19. The idea of the presented platform fits into the broadly understanding of Building Information Modeling. After introducing the methodology, stages of the inventory and follow-up process carried out within the platform are illustrated and discussed on the basis of a case study. Based on the obtained results it can be concluded that the proposed methodology creates a convenient, efficient and inexpensive tool for massive inspection of building resources in large areas. The inventory is based primarily on high-quality photo and video material obtained from the deck of an unmanned aerial vehicle and the expert knowledge of the inspector conducting the inspection. By combining digital images data (photos, 3D model, orthophotos) with substantive data (facade element classification tables, wear / defect classification tables), we get a platform that allows intuitive access to viewing, classification, editing and analysis of selected data.</text>
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                <text>2020</text>
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                <text>monitoring, GIS, bim, UAV, building condition assessment</text>
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                <text>Tehnički Glasnik</text>
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                <text>University North</text>
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                <text>Technology</text>
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                <text>Recensione di Scaffai, Niccolò. Letteratura e ecologia. Forme e temi di una relazione narrativa. Carocci, 2017.     Review of Scaffai, Niccolò. Letteratura e ecologia. Forme e temi di una relazione narrativa. Carocci, 2017.</text>
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                <text>Enthymema</text>
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                <text>Università degli Studi di Milano</text>
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                <text>Literature (General), Language. Linguistic theory. Comparative grammar, Style. Composition. Rhetoric, Oratory. Elocution, etc.</text>
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                <text>&lt;a href="https://riviste.unimi.it/index.php/enthymema/article/view/10936" target="_blank" rel="noreferrer noopener"&gt;https://riviste.unimi.it/index.php/enthymema/article/view/10936&lt;/a&gt;</text>
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                <text>MIND-VR: Design and Evaluation Protocol of a Virtual Reality Psychoeducational Experience on Stress and Anxiety for the Psychological Support of Healthcare Workers Involved in the COVID-19 Pandemic</text>
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                <text>Carlo Caltagirone, Federica Pallavicini, Eleonora Orena, Simona di Santo, Simona di Santo, Luca Greci, Chiara Caragnano, Paolo Ranieri, Costanza Vuolato, Alessandro Pepe, Guido Veronese, Antonios Dakanalis, Angelo Rossini, Massimo Clerici, Fabrizia Mantovani</text>
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                <text>To ensure the continuity of healthcare and to counter the spread of the COVID-19 pandemic, doctors and nursing staff at hospitals must face an insidious, invisible danger that is stretching the healthcare system far past its capacity. Excessive workload, inadequate protection from contamination, the need to manage patients experiencing extreme suffering and being kept apart from their families put medical personnel at high risk to experience stress and anxiety. Numerous scientific studies have shown that, among various therapeutic programs, virtual reality represents a highly specialized and effective tool for the prevention and treatment of stress and anxiety. However, the solutions developed using this technology for the management of stress and anxiety induced by the COVID-19 pandemic are still very limited, and none of these have been developed specifically for use with healthcare professionals. Therefore, this paper will detail the design and evaluation protocol of MIND-VR, a virtual reality-based psychoeducational experience on stress and anxiety developed following a user-centered design approach. The virtual experience will be tested on a sample of Italian hospital healthcare personnel involved in the COVID-19 pandemic emergency. MIND-VR is available free of charge, both in Italian and English, on the project website (https://mind-vr.com/).</text>
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                <text>Healthcare workers, Anxiety, covid-19, Stress, Virtual Reality, Psychoeducation</text>
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                <text>Epidemiology and Health</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Electronic computers. Computer science</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Sex Hormones and Hormone Therapy during COVID-19 Pandemic: Implications for Patients with Cancer</text>
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            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="81772">
                <text>Carlo Cattrini, Francesco Boccardo, Melissa Bersanelli, Maria  Maddalena Latocca, Benedetta Conte, Giacomo Vallome</text>
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                <text>The novel coronavirus disease 2019 (COVID-19) shows a wide spectrum of clinical presentations, severity, and fatality rates. The reason older patients and males show increased risk of severe disease and death remains uncertain. Sex hormones, such as estradiol, progesterone, and testosterone, might be implicated in the age-dependent and sex-specific severity of COVID-19. High testosterone levels could upregulate transmembrane serine protease 2 (TMPRSS2), facilitating the entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into host cells via angiotensin-converting enzyme 2 (ACE2). Data from patients with prostate cancer treated with androgen-deprivation therapy seem to confirm this hypothesis. Clinical studies on TMPRSS2 inhibitors, such as camostat, nafamostat, and bromhexine, are ongoing. Antiandrogens, such as bicalutamide and enzalutamide, are also under investigation. Conversely, other studies suggest that the immune modulating properties of androgens could protect from the unfavorable cytokine storm, and that low testosterone levels might be associated with a worse prognosis in patients with COVID-19. Some evidence also supports the notion that estrogens and progesterone might exert a protective effect on females, through direct antiviral activity or immune-mediated mechanisms, thus explaining the higher COVID-19 severity in post-menopausal women. In this perspective, we discuss the available evidence on sex hormones and hormone therapy in patients infected with SARS-CoV-2, and we highlight the possible implications for cancer patients, who can receive hormonal therapies during their treatment plans.</text>
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                <text>2020</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="81775">
                <text>covid-19, SARS-CoV-2, Testosterone, Androgens, progesterone, Estrogens</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="81776">
                <text>10.3390/cancers12082325</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="81777">
                <text>Epidemiology and Health</text>
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          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="81778">
                <text>Korean Society of Epidemiology</text>
              </elementText>
            </elementTextContainer>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="81779">
                <text>Neoplasms. Tumors. Oncology. Including cancer and carcinogens</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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                <text>Genome-wide analysis of DNA methylation, copy number variation, and gene expression in monozygotic twins discordant for primary biliary cirrhosis</text>
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                <text>Carlo eSelmi, Francesca eCavaciocchi, Ana eLleo, Cristina eCheroni, Raffaele eDe Francesco, Simone A. Lombardi, Maria eDe Santis, Francesca eMeda, Maria Gabriella eRaimondo, Chiara eCrotti, Marco eFolci, Luca eZammataro, Marlyn J. Mayo, Nancy eBach, Shinji eShimoda, Stuart eGordon, Monica eMiozzo, Pietro eInvernizzi, Mauro ePodda, Rossana eScavelli, Michelle R. Martin, Michael Forrest Seldin, Janine M. LaSalle, M. Eric eGershwin</text>
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                <text>Primary biliary cirrhosis (PBC) is an uncommon autoimmune disease with a homogeneous clinical phenotype that reflects incomplete disease concordance in monozygotic (MZ) twins. We have taken advantage of a unique collection consisting of genomic DNA and mRNA from peripheral blood cells of female MZ twins (n=3 sets) and sisters of similar age (n=8 pairs) discordant for disease. We performed a genome-wide study to investigate differences in (i) DNA methylation (using a custom tiled 4-plex array containing tiled 50-mers 19,084 randomly chosen methylation sites), (ii) copy number variation (CNV) (with a chip including markers derived from the 1000 Genomes Project, all three HapMap phases, and recently published studies), and/or (iii) gene expression (by whole-genome expression arrays). Based on the results obtained from these three approaches we utilized quantitative PCR to compare the expression of candidate genes. Importantly, our data support consistent differences in discordant twins and siblings for the (i) methylation profiles of 60 gene regions, (ii) CNV of 10 genes, and (iii) the expression of 2 interferon-dependent genes. Quantitative PCR analysis showed that 17 of these genes are differentially expressed in discordant sibling pairs. In conclusion, we report that MZ twins and sisters discordant for PBC manifest particular epigenetic differences  and highlight the value of the epigenetic study of twins.</text>
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                <text>2014</text>
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            <name>Subject</name>
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                <text>twins, Monozygotic, epigenetics, Primary biliary cirrhosis, environment, Autoimmune cholangitis</text>
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                <text>DOI: 10.3389/fimmu.2014.00128</text>
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            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="4505">
                <text>Frontiers in Immunology</text>
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                <text>Frontiers Media S.A.</text>
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                <text>Immunologic diseases. Allergy</text>
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            <description>A language of the resource</description>
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                <text>EN</text>
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                <text>Produção de Azolla como fonte proteica na avicultura: estudo de caso em avicultores familiares no Rio Grande do Sul</text>
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                <text>Carlo Juliantro Giehl, Darwin Aranda Chuquillanque, Carmem Rejane Pacheco Porto, Eduardo Antunes Dias, Marcelo Tempel Stumpf</text>
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            <description>An account of the resource</description>
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                <text>O presente trabalho relata as atividades envolvidas no planejamento e construção de tanques para produção de Azolla sp., planta aquática com potencial de uso para alimentação de aves. As ações ocorreram em Capão do Leão e São Lourenço do Sul, municípios na zona Sul do Rio Grande do Sul. Foram construídos dois modelos, um externo aos piquetes de criação (Capão do Leão) e um interno aos mesmos (São Lourenço do Sul). Percebeu-se rápida propagação da Azolla nos tanques e preenchimento completo dos mesmos após cerca de 14 dias de cultivo. O sombreamento foi fundamental para o bom desenvolvimento da Azolla e manutenção de sua coloração esverdeada. Ausência de sombra promoveu alterações de cor e aumento na população de outras espécies vegetais. Houve excelente aceitação da Azolla pelas galinhas. Fornecer Azolla dentro dos piquetes resultou em consumo exagerado, promovendo queda drástica na população vegetal, a qual demorou para se restabelecer e passou a competir com outras espécies. Percebeu-se melhor controle e manutenção da população de Azolla quando o tanque foi construído na área externa aos piquetes, embora, nesse caso, o fornecimento venha a requerer maior mão de obra. O baixo custo, rápida propagação e facilidade de cultivo de Azolla podem vir a encorajar outros criadores a cultivá-la como fonte nutricional para suas galinhas.</text>
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                <text>Alimentação animal alternativa, avicultura familiar, manejo agroecológico</text>
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                <text>10.18378/rvads.v16i3.8314</text>
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                <text>Revista Verde de Agroecologia e Desenvolvimento Sustentável</text>
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                <text>Grupo Verde de Agroecologia e Abelhas (GVAA)</text>
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                <text>Agriculture (General), Geography. Anthropology. Recreation, Environmental sciences</text>
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                <text>&lt;a href="https://www.gvaa.com.br/revista/index.php/RVADS/article/view/8314" target="_blank" rel="noreferrer noopener"&gt;https://www.gvaa.com.br/revista/index.php/RVADS/article/view/8314&lt;/a&gt;</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>COVID-19 and Cardiac Surgery: Still Many Questions and Much Work to Do.</text>
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                <text>Carlo M Rosati, Chan Tran N Nguyen, Shinichi Fukuhara</text>
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                <text>10.1016/j.athoracsur.2021.02.067</text>
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                <text>The Annals of thoracic surgery</text>
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