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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Adding Colchicine to the Antiretroviral Medication - Lopinavir/Ritonavir (Kaletra) in Hospitalized Patients with Non-Severe Covid-19 Pneumonia: A Structured Summary of a Study Protocol for a Randomized Controlled Trial</text>
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                <text>Shadi Ziaie, Mohsen Nafar, Alireza Kashefi Zadeh, Shiva Samavat, Fariba Samadian, Ahmad Firouzan, Somayeh Fatemizadeh, Nooshin Dalili, Fatemeh Poorrezagholi</text>
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                <text>Abstract Objectives Colchicine is a well-known drug, which has been used for years to treat a wide range of rheumatic and inflammatory disorders. It helps break the cycle of inflammation through diverse mechanisms including reducing Intereukin-6, Interleukin-8, Tumour Necrosis Factor-alpha besides controlling oxidative stress pathways which all are important and pathologic components in the clinical course and outcome of patients infected with COVID-19. This study aims to assess the anti-inflammatory effects of colchicine in non-severe hospitalized COVID-19 patients. Trial design Prospective, randomized (1:1 ratio), double blind study with parallel group design. Participants Hospitalized patients with positive nasopharyngeal swab for COVID-19 infection (RT -PCR) and lung Computed tomography scan involvement compatible with COVID-19 pneumonia. The patients are not severely hypoxic, do not need intubation or invasive oxygenation. Exclusion criteria: known hypersensitivity to colchicine; known hepatic failure; estimated glomerular filtration rate (eGFR)450 msec. Participants will be recruited from inpatients at Labbafinejad Meidcal Center , Tehran, Iran. Intervention and comparator Eligible enrolled patients will be randomized into two groups. Group A will receive the antiretroviral Lopinavir/Ritonavir (Kaletra) while group B will receive Lopinavir/Ritonavir (Kaletra) + Colchicine 1.5 mg loading then 0.5 mg twice daily orally. All patients in both groups will receive the same amounts of essential minerals, vitamins as antioxidants, and antibiotics. Patients of both groups will be treated under optimal treatment based on the CDC and WHO guidelines and national consensus proposed in Iran including the same dosages of Lopinavir/Ritonavir, antibiotics, trace elements and antioxidants while only in group-B patients Colchicine will be added on top of this protocol. Main outcomes Primary: Time for clinical improvement and lung CT score changes 14 days after treatment. Secondary: 14 days after treatment – C-Reactive Protein test x Neutrophil to Lymphocyte Ratio , Interleukin-6, malondialdehyde (MDA) levels reduction – Percentage of patients who require supplemental Oxygen – Mean hospital stay length Randomisation Patients will be allocated to each group (ratio 1:1) by using an online randomization tool: http://www.graphpad.com/quickcalcs/index.cfm Blinding (masking) This will be a double-blind study in which participants and those assessing the final outcomes will be blinded to group assignment. Numbers to be randomised (sample size) Regarding the pandemic crisis and our center capacity to hospitalize confirmed COVID-19 patients, a total of 80 patients was found to be logical to be randomized into two groups of 40- patients. Trial Status Recruitment is ongoing. Recruitment began on 20/03/2020 and the date by which the recruitment is anticipated to be completed is 30/05/2020. Trial registration ClinicalTrials.gov Identifier: NCT04360980, registered 24/04/2020. Full protocol The full protocol is attached as an additional file, accessible from the Trials website (Additional file 1). In the interest in expediting dissemination of this material, the familiar formatting has been eliminated; this Letter serves as a summary of the key elements of the full protocol.</text>
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                <text>2020</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>oxidative stress, inflammation, Randomised controlled trial, protocol, Colchicine, COVID-19</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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                <text>DOI: 10.1186/s13063-020-04455-3</text>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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                <text>Trials</text>
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                <text>BMC</text>
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                <text>Medicine (General)</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
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                <text>An Influence of Group Purchasing Organizations on Financial Security of SMEs Operating in the Renewable Energy Sector—Case for Poland</text>
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            <description>An entity primarily responsible for making the resource</description>
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                <text>Marek  Sobolewski, Grzegorz Lew, Grzegorz Zimon</text>
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            <description>An account of the resource</description>
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                <text>European countries are increasingly using renewable energy. Poland is an outsider of such solutions. The Polish energy sector is primarily based on energy produced from coal. However, environmental changes and regulations of the European Union are forcing the increased use of energy from renewable sources. Renewable energy is an industry that is still developing in Poland. At the same time, Poland is a country where the political decisions of the government over the last few years have resulted in a significant limitation of the possibilities of renewable energy development. These actions have also resulted in lowering the profitability of the currently operating renewable energy enterprises, especially those from the sector of small and medium-sized enterprises. An opportunity for SMEs operating in the renewable energy sector is to merge into industry purchasing groups. The aim of the article—and at the same time the research question—is: Is it financially safer for renewable energy companies to operate within purchasing groups compared to companies operating independently in this industry? Traditional ways of purchasing can be transferred to integrated purchasing systems, which will be created by purchasing groups associating renewable energy companies. For this purpose, the financial effects of the implementation and functioning of the purchasing groups in the renewable energy sector in relation to entities operating independently were examined. In the research of renewable energy SMEs, a comparative analysis of key indicators determining the possibility of continuing the activity of these entities was made. The following indicators were examined: current financial liquidity ratio, return on sales, operating cycle, cash conversion cycle, share of receivables in current assets, share of inventory in current assets, turnover ratios, level of receivables, liabilities and profitability. The scientific literature is dominated by studies on purchasing groups in the pharmaceutical and construction industries. Thanks to the research conducted, it has been indicated that the renewable energy industry can also improve its profitability, and thus the possibility of safe continuation of operations by extending the business model to inter-entity cooperation within purchasing groups. Increasing the efficiency of individual entities of the renewable energy industry within purchasing groups becomes particularly important during the COVID-19 pandemic. Statistical analyses and their graphic presentation present the significant impact on the safety and profitability of renewable energy entities in the form of purchasing groups.</text>
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                <text>2020</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>renewable energy, bankruptcy, financial liquidity, group purchasing organizations, Polish energy</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="34150">
                <text>DOI: 10.3390/en13112926</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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                <text>Energies</text>
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            <description>An entity responsible for making the resource available</description>
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                <text>MDPI AG</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Technology</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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            </element>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>The Universe, the Light, the Earth, the Life: the Reality is Greater than We Are</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="34155">
                <text>Vincenzo  Balzani</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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                <text>The pandemic caused by Covid-19 locked us at home for several weeks. Some clever town councillors took this opportunity to offer their citizens cultural pills. In my little town I was asked to present a few short lectures on general scientific concepts. I tried to link together four entities of reality (Universe, Light, Earth and Life) showing that reality is much more complex than we think and much greater than us. E.g.: age of the Universe vs age of human civilization (~1.3x1010 vs ~ 1x104 years), size of universe vs human size (~1x1025 m vs ~1 m), velocity of light vs velocity of sound (3x108 vs 3.5x102 m/s), number of stars in the sky (~ 1x1023), number of molecule in a drop of water (~ 3x1021), number of atoms in a human body (~ 1x1027). Although we know reasonably well how Universe, Light, Earth and Life “work”, we are still surrounded by profound mysteries related to the why questions, i.e., the “questions of meaning”, that science cannot answer. Such questions, e.g., why is there the Universe? Why is there Life in this insignificant fragment of the Universe called Earth? Why did the evolution of Life lead to human? What's the meaning of my life? What is the meaning of the Covid-19 pandemic? The answers to the these “questions of meaning”, that cannot be given by science, are discussed in the enciclic Laudato si’ of pope Francis in relation to the ecological and social crisis we are going through.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2020</text>
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            <name>Subject</name>
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                <text>Complexity, reality, Light, earth, Universe, Life</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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                <text>DOI: 10.13128/Substantia-957</text>
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                <text>Substantia</text>
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              <elementText elementTextId="34161">
                <text>Firenze University Press</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Chemistry, History (General) and history of Europe</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>SARS-CoV-2 Genome Analysis of Japanese Travelers in Nile River Cruise</text>
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                <text>Tamano Matsui, Makoto Kuroda, Tsuyoshi Sekizuka, Michiyo Shinohara, Yusuke Kobayashi, Hajime Kamiya, Yushi Hachisu, Motoi Suzuki, Akihiko Tokaji, Masakatsu Taira, Kentaro Itokawa, Keisuke Kadokura, Sanae Kuramoto, Eri Nariai, Tsuyoshi Kishimoto</text>
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                <text>Japan has reported 26 cases of coronavirus disease 2019 (COVID-19) linked to cruise tours on the River Nile in Egypt between March 5 and 15, 2020. Here, we characterized the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome of isolates from 10 travelers who returned from Egypt and from patients possibly associated with these travelers. We performed haplotype network analysis of SARS-CoV-2 isolates using genome-wide single-nucleotide variations. Our analysis identified two potential Egypt-related clusters from these imported cases, and these clusters were related to globally detected viruses in different countries.</text>
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                <text>2020</text>
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                <text>imported case, cruise ship, haplotype network, genome epidemiology, Single nucleotide variations</text>
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                <text>DOI: 10.3389/fmicb.2020.01316</text>
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                <text>Frontiers in Microbiology</text>
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                <text>Frontiers Media S.A.</text>
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                <text>Microbiology</text>
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                <text>In the face of elevated pandemic risk, canonical epidemiological models imply the need for extreme social distancing over a prolonged period. Alternatively, people could be organized into zones, with more interactions inside their zone than across zones. Zones can deliver significantly lower infection rates, with less social distancing, particularly if combined with simple quarantine rules and contact tracing. This paper provides a framework for understanding and evaluating the implications of zones, quarantines, and other complementary policies.</text>
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                <text>The COVID-19 pandemic has caused a surge of demand for medical supplies and spare parts, which has put pressure on the manufacturing sector. As a result, 3D printing communities and companies are currently operating to ease the breakdown in the medical supply chain. If no parts are available, 3D printing can potentially be used to produce time-critical parts on demand such as nasal swabs, face shields, respirators, and spares for ventilators. A structured search using online sources and feedback from key experts in the 3D printing area was applied to highlight critical issues and to suggest potential solutions. The prescribed outcomes were estimated in terms of cost and productivity at a small and large scale. This study analyzes the number and costs of parts that can be manufactured with a single machine within 24 h. It extrapolates this potential with the number of identical 3D printers in the world to estimate the global potential that can help practitioners, frontline workers, and those most vulnerable during the pandemic. It also proposes alternative 3D printing processes and materials that can be applicable. This new unregulated supply chain has also opened new questions concerning medical certification and Intellectual property rights (IPR). There is also a pressing need to develop new standards for 3D printing of medical parts for the current pandemic, and to ensure better national resilience.</text>
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                <text>DOI: 10.3390/app10114004</text>
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                <text>Biology (General), Technology, Physics, Chemistry, Engineering (General). Civil engineering (General)</text>
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                <text>تهدف هذه الدراسة إلى تشخيص و كشف الظروف والأسباب التي أدت إلى انتقال الصدمة الصحية إلى القطاع الاقتصادي. كما تهدف أيضا إلى تفصيل مظاهر حساسية الاقتصاد العالمي للاختلالات وأسباب تسارعها في ظل جائحة Covid-19، من خلال وصف وتحليل حيثيات الصدمة والتحري عن خلفياتها المالية بالإضافة إلى البحث عن الحلول الممكنة.  خلصت الدراسة إلى أن الجموح في تداول الأصول المالية عالية الخطر دون تقنيات رشيدة للتغطية واتساع حجم الأسواق المالية، بالإضافة إلى غياب الضابط الأخلاقي، ومظاهر العولمة الاقتصادية غير متزنة هي العوامل الأساسية لهشاشة الاقتصاد العالمي، وأن اعتماد سياسات مالية ونقدية غير تقليدية وخاصة أسس الاقتصاد الإسلامي كفيل بكبح الآثار السلبية للصدمات.  تصنيف جال: F40،G01، G38، H12.</text>
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                <text>مجلة بحوث الإدارة والاقتصاد</text>
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                <text>faculty of Economics, Commercial and Management Sciences</text>
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                <text>Aim: Sleep is a physiological condition that is needed by the animal organism and required for the regular function of organ systems and mental health. The recent COVID-19 pandemic caused widespread anxiety worldwide with health-related, economic, and social burdens. The aim of this study is to determine the sleep-related perturbances and the level of anxiety in a Turkish population and compare the outcomes between the genders and working status of the subjects during the COVID-19 pandemic.Methods: We performed a phone-based cross-sectional semi-structured questionnaire on 100 adult volunteers in May 2020. Sociodemographic data, the responses for ten questions on sleep performance and their level of anxiety and life satisfaction were noted and reported. Results: Male subjects reported a higher incidence of change in their waking hours, and an increased need for sleep during daytime (P=0.008). The anxiety level was significantly higher among female subjects, and the main causes of the anxiety were different between the two groups (P=0.035, P&amp;lt;0.001, respectively). Female subjects described a higher rate of change in their well-being (P&amp;lt;0.001), and the overall scores for well-being and life satisfaction were significantly lower among the females (P&amp;lt;0.001). The non-working group had an increased incidence of severe anxiety and an increased ratio of change in their lifestyle in comparison to usual (P=0.006, P&amp;lt;0.001, respectively). Conclusions: To our knowledge, this report is the first survey analysis on anxiety and sleep performance following the COVID-19 infections in Turkey. We report a high incidence of impaired sleep status, change of lifestyle, satisfaction, and increased anxiety in the population independent from the gender and current working status.</text>
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          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="34211">
                <text>2020</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="34212">
                <text>Anxiety, Pandemic, Kaygı, COVID-19, Pandemi, uyku durumu, sleeping status</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="34213">
                <text>DOI: 10.28982/josam.737088</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="34214">
                <text>Journal of Surgery and Medicine</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="34215">
                <text>Journal of Surgery and Medicine</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="34216">
                <text>Surgery, Medicine (General), Medicine</text>
              </elementText>
            </elementTextContainer>
          </element>
        </elementContainer>
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    </elementSetContainer>
  </item>
  <item itemId="3718" public="1" featured="0">
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      <file fileId="3718">
        <src>https://www.socictopen.socict.org/files/original/e7dd17141fb65bbfe9ab5360d51149b5.pdf</src>
        <authentication>cb92232d8f04f042343e7b4bde918bda</authentication>
      </file>
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        <elementSet elementSetId="1">
          <name>Dublin Core</name>
          <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
          <elementContainer>
            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="1">
                  <text>Coronavirus</text>
                </elementText>
              </elementTextContainer>
            </element>
            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
                </elementText>
              </elementTextContainer>
            </element>
          </elementContainer>
        </elementSet>
      </elementSetContainer>
    </collection>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
    </itemType>
    <elementSetContainer>
      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
        <elementContainer>
          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="34217">
                <text>Covid-19 Predictions Using a Gauss Model, Based on Data from April 2</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="34218">
                <text>Martin Kröger, Reinhard Schlickeiser, Frank Schlickeiser, Janik Schüttler</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="34219">
                <text>We study a Gauss model (GM), a map from time to the bell-shaped Gaussian function to model the deaths per day and country, as a simple, analytically tractable model to make predictions on the coronavirus epidemic. Justified by the sigmoidal nature of a pandemic, i.e., initial exponential spread to eventual saturation, and an agent-based model, we apply the GM to existing data, as of 2 April 2020, from 25 countries during first corona pandemic wave and study the model’s predictions. We find that logarithmic daily fatalities caused by the coronavirus disease 2019 (Covid-19) are well described by a quadratic function in time. By fitting the data to second order polynomials from a statistical     χ 2    -fit with 95% confidence, we are able to obtain the characteristic parameters of the GM, i.e., a width, peak height, and time of peak, for each country separately, with which we extrapolate to future times to make predictions. We provide evidence that this supposedly oversimplifying model might still have predictive power and use it to forecast the further course of the fatalities caused by Covid-19 per country, including peak number of deaths per day, date of peak, and duration within most deaths occur. While our main goal is to present the general idea of the simple modeling process using GMs, we also describe possible estimates for the number of required respiratory machines and the duration left until the number of infected will be significantly reduced.</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="34220">
                <text>2020</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="34221">
                <text>virus, extrapolation, parameter estimation, Health science, statistical methods in physics, pandemic spreading</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="34222">
                <text>DOI: 10.3390/physics2020013</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="34223">
                <text>Physics</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="34224">
                <text>MDPI AG</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="34225">
                <text>Physics</text>
              </elementText>
            </elementTextContainer>
          </element>
        </elementContainer>
      </elementSet>
    </elementSetContainer>
  </item>
</itemContainer>
