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                <text>A World of Changes: The Inheritance of COVID-19</text>
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                <text>Manica Negahdaripour</text>
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                <text>DOI: 10.30476/ijms.2020.46530</text>
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                <text>Iranian Journal of Medical Sciences</text>
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                <text>Shiraz University of Medical Sciences</text>
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                <text>Medicine (General)</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>THE PROBLEMS OF THE PSYCHOLOGICAL AND PSYCHOTHERAPEUTICAL AID DURING THE CORONAVIRAL EPIDEMY (ON THE EXAMPLE OF GERMANY)</text>
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                <text>Elena A. Bauer</text>
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                <text>Purpose. On the example of Germany the article focuses on the study of the influence of the consequences of the situation connected with the coronaviral epidemy on the people’s psychic state (especially those suffering from various mental diseases), as well as on the problems of psychological and psychotherapeutical aid for patients during the coronaviral epidemy. Methodology and Approach. On the ground of the analysis of the psychological literature, mass media messages and work experience as psychotherapeutist the concrete organizational measures of the psychological and psychotherapeutical assistance for different strata of population have been characterized.Results. The article describes the experience of the practical work with patients during the COVID-19 epidemy at the medical psychotherapeutical centre; in particular, how to overcome the consequences of the self-isolation and other restrictions, which negatively influence the human’s full-fledged social and psychological functioning. The emphasis is put on the remote patient work forms, such as video consultations. Theoretical and Practical implication. The article makes some contribution to the study of the epidemy’s social and psychological consequences and organization of the psychological assistance system for different strata of population in epidemic conditions. The psychological assistance methods, set forth in this article, can be useful for their practical application to cope with the negative consequences of the epidemy.</text>
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                <text>stress, patient, psychotherapy, Epidemy, mental diseases psychological aid</text>
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                <text>DOI: 10.18384/2224-0209-2020-2-1009</text>
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                <text>Вестник Московского государственного областного университета</text>
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                <text>Moscow Region State University Editorial Office</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Antibody Dependent Enhancement Due to Original Antigenic Sin and the Development of SARS</text>
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                <text>Walter Fierz, Brigitte Walz</text>
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                <text>Human coronavirus (HCoV) is one of the most common causes of respiratory tract infections throughout the world. Two phenomena observed so far in the development of the SARS-CoV-2 pandemic deserve further attention. First, the relative absence of clinical signs of infections in children, second, the early appearance of IgG in certain patients. From the point of view of immune system physiology, such an early rise of specific IgG is expected in secondary immune responses when memory to a cross-reactive antigen is present, usually from an earlier infection with a coronavirus. It is actually typical for the immune system to respond, to what it already knows, a phenomenon that has been observed in many infections with closely related viruses and has been termed “original antigenic sin.” The question then arises whether such cross-reactive antibodies are protective or not against the new virus. The worst scenario would be when such cross-reactive memory antibodies to related coronaviruses would not only be non-protective but even enhance infection and the clinical course. Such a phenomenon of antibody dependent enhancement (ADE) has already been described in several viral infections. Thus, the development of IgG against SARS-CoV-2 in the course of COVID-19 might not be a simple sign of viral clearance and developing protection against the virus. On the contrary, due to cross-reaction to related coronavirus strains from earlier infections, in certain patients IgG might enhance clinical progression due to ADE. The patient's viral history of coronavirus infection might be crucial to the development of the current infection with SARS-CoV-2. Furthermore, it poses a note of caution when treating COVID-19 patients with convalescent sera.</text>
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                <text>2020</text>
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                <text>cross-reactivity, antibody-dependent enhancement (ADE), Receptor binding protein, COVID-19, antigenic sin, protecting IgG</text>
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                <text>DOI: 10.3389/fimmu.2020.01120</text>
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                <text>Frontiers in Immunology</text>
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                <text>Frontiers Media S.A.</text>
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                <text>Immunologic diseases. Allergy</text>
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                <text>Coronavirus Disease 2019 (COVID‐19): Morocco Interrupting the Transmission by Ethics, Logistics, and Therapeutics Efforts</text>
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                <text>Boujamaa Imziln, Soraia El Baz</text>
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                <text>Since the first case of 2019 novel coronavirus (COVID-19) identified on 02 March 2020 in Morocco, the number of cases rapidly increased, resulting in 3046 cases including 143 deaths as of 20 April 2020. Morocco used every possibility (socio-economic and medical) to control and to limit the spread of COVID-19 and support the implementation of social distancing measures to quickly control the outbreak. The percentage of death was 4.7% as of 20 April 2020, and increases with older age. The median age of the deaths was 65 years. Moroccan government noted that 80% of the death had health problems, 15% of positive COVID-19 cases show no symptoms and only 11.5% of patients were recovered. This report examines the impact of the ongoing pandemic of COVID-19 in Morocco. The Moroccan government has considered being more effective in responding to the pandemic. Persistent efforts have been made to limit the transmission of COVID-19, and many strategies to protect people against COVID-19 is running well to keep the spread of coronavirus under control in comparison with other countries in Europe or Africa (especially North Africa). In this report, in contrast, the situation demonstrates the need of rapid and accurate detection and identification methods that can be used in hospitals bearing the burden of identifying and treating patients. Also, this paper demonstrate that the different measures adapted by Morocco can be a good example for other developing countries and used to fight COVID-19 before it reaches the poorest countries of the world.</text>
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                <text>chloroquine, coronavirus, Morocco, containment, social distancing, COVID-19</text>
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                <text>DOI: 10.5799/jcei/8214</text>
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                <text>Journal of Clinical and Experimental Investigations</text>
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                <text>Medicine</text>
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                <text>COVID-19 Pandemic in North Cyprus</text>
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                <text>Aysen Berberoglu</text>
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                <text>When COVID -19, the novel coronavirus leading to severe acute respiratory syndrome, first identified in Wuhan China during December 2019, Northern Cyprus community would never imagine the virus could make its way to the less populated and mostly isolated part of the island. During the first week of March 2020, the uneasiness was in the minds of people and suspected coronavirus cases started to surface. However, until 10th of March 2020, the suspected cases were found COVID-19 negative. On 10th of March 2020, the first positive case of COVID -19 was reported who was a German woman tourist, arrived with a charter flight two days before. By 12th of April, North Cyprus had a total of 99 positive COVID -19 cases, 3 deaths and 57 recovered.</text>
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            <name>Subject</name>
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                <text>Pandemic, North Cyprus, COVID-19</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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                <text>DOI: 10.5799/jcei/8213</text>
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            <name>Source</name>
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                <text>Journal of Clinical and Experimental Investigations</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>Association of Health Investigations</text>
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                <text>Medicine</text>
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              <name>Title</name>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
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                <text>A Retrospective Analysis of the Clinical and Epidemiological Characteristics of COVID-19 Patients in Henan Provincial People's Hospital, Zhengzhou, China</text>
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                <text>Jing Zhao, Ziyi Feng, Qijun Wu, Haoyu Gao</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>Objective: This study evaluated the clinical and epidemiological characteristics of patients with confirmed coronavirus disease 2019 (COVID-19).Methods: This retrospective study evaluated 29 patients with confirmed COVID-19 infection admitted to Henan Provincial People's Hospital between January 27 and February 27, 2020, with follow-up until April 01, 2020.Results: The median age of the patients was 56 years. Nineteen (19/29; 65.5%) had underlying conditions including cardiovascular disease, digestive disease, or type 2 diabetes mellitus. Twenty-two (22/29; 76%) had close contact with acquaintances or family members who were confirmed or probable COVID-19 cases. Many patients had white blood cell counts with abnormal neutrophil and lymphocyte numbers, abnormal hemoglobin concentration, coagulation profiles, and blood biochemistry, and increased infection markers. Mottling and multiple ground-glass opacities were seen in X-ray images of 19 patients (19/29; 65.5%). Most patients (23/29; 79.8%) received supplemental oxygen therapy and antibiotics (23/29; 79.8%) in addition to traditional Chinese medicines (26/29; 89.7%). The most frequent presenting symptoms were fever, cough, and sputum production. One patient, an 86-years-old woman with more than one underlying disease, died during follow-up. Patients with severe disease were significantly older and more likely to have been transferred from other healthcare facilities than those with mild disease. Anemia, decreased activated partial thromboplastin time, calcium, and albumin, and increased D-dimer and interleukin-6 were more frequent in severe disease. Need of oxygen therapy, mechanical ventilation, intravascular immunoglobulin, and duration of antibiotic therapy were increased in those with severe disease.Conclusions: Significant differences in demographical and clinical characteristics were observed in patients with moderate and severe COVID-19.</text>
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                <text>2020</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>Epidemiology, traditional Chinese medicine, clinical characteristics, SARS-CoV-2, corona virus disease 2019</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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                <text>DOI: 10.3389/fmed.2020.00286</text>
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            </elementTextContainer>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="34617">
                <text>Frontiers in Medicine</text>
              </elementText>
            </elementTextContainer>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="34618">
                <text>Frontiers Media S.A.</text>
              </elementText>
            </elementTextContainer>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Medicine (General)</text>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                <elementText elementTextId="1">
                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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              </elementTextContainer>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="34620">
                <text>Does Early Childhood Vaccination Protect Against COVID-19?</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="34621">
                <text>Rimantas Kodzius, Shakhawan M. Ali, Dana Khdr Sabir, Karzan R Sidiq</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>The coronavirus disease 2019 (COVID-19) is an on-going pandemic caused by the SARS-coronavirus-2 (SARS-CoV-2) which targets the respiratory system of humans. The published data show that children, unlike adults, are less susceptible to contracting the disease. This article aims at understanding why children constitute a minor group among hospitalized COVID-19 patients. Here, we hypothesize that the measles, mumps, and rubella (MMR) vaccine could provide a broad neutralizing antibody against numbers of diseases, including COVID-19. Our hypothesis is based on the 30 amino acid sequence homology between the SARS-CoV-2 Spike (S) glycoprotein (PDB: 6VSB) of both the measles virus fusion (F1) glycoprotein (PDB: 5YXW_B) and the rubella virus envelope (E1) glycoprotein (PDB: 4ADG_A). Computational analysis of the homologous region detected the sequence as antigenic epitopes in both measles and rubella. Therefore, we believe that humoral immunity, created through the MMR vaccination, provides children with advantageous protection against COVID-19 as well, however, an experimental analysis is required.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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              <elementText elementTextId="34623">
                <text>2020</text>
              </elementText>
            </elementTextContainer>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="34624">
                <text>Children, Immunity, rubella, virus, Measles, COVID-19</text>
              </elementText>
            </elementTextContainer>
          </element>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="34625">
                <text>DOI: 10.3389/fmolb.2020.00120</text>
              </elementText>
            </elementTextContainer>
          </element>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="34626">
                <text>Frontiers in Molecular Biosciences</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="34627">
                <text>Frontiers Media S.A.</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="34628">
                <text>Biology (General)</text>
              </elementText>
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        <src>https://www.socictopen.socict.org/files/original/bd74a194b1c2a2ce5ad4e6155eda73e6.pdf</src>
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          <name>Dublin Core</name>
          <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="1">
                  <text>Coronavirus</text>
                </elementText>
              </elementTextContainer>
            </element>
            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
                </elementText>
              </elementTextContainer>
            </element>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="34629">
                <text>Real-time reverse transcription loop-mediated isothermal amplification for rapid detection of SARS-CoV-2</text>
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            </elementTextContainer>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="34630">
                <text>I-Ching Sam, Yee Ling Lau, Afifah Hassan, Pik-Pin Goh, Yee Leng Lee, Meng-Yee Lai, Kalaiarasu M. Peariasamy, Yoong Min Chong, Ilyiana Ismail, Nur Izati Mustapa, Tuan Suhaila Tuan Soh</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="34631">
                <text>Background Highly sensitive real-time reverse transcription polymerase chain reaction (RT-qPCR) methods have been developed for the detection of SARS-CoV-2. However, they are costly. Loop-mediated isothermal amplification (LAMP) assay has emerged as a novel alternative isothermal amplification method for the detection of nucleic acid. Methods A rapid, sensitive and specific real-time reverse transcription LAMP (RT-LAMP) assay was developed for SARS-CoV-2 detection. Results This assay detected one copy/reaction of SARS-CoV-2 RNA in 30 min. Both the clinical sensitivity and specificity of this assay were 100%. The RT-LAMP showed comparable performance with RT-qPCR. Combining simplicity and cost-effectiveness, this assay is therefore recommended for use in resource resource-limited settings.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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              <elementText elementTextId="34632">
                <text>2020</text>
              </elementText>
            </elementTextContainer>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="34633">
                <text>diagnosis, RT-LAMP, rapid detection, COVID-19</text>
              </elementText>
            </elementTextContainer>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="34634">
                <text>DOI: 10.7717/peerj.9278</text>
              </elementText>
            </elementTextContainer>
          </element>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="34635">
                <text>PeerJ</text>
              </elementText>
            </elementTextContainer>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="34636">
                <text>PeerJ Inc.</text>
              </elementText>
            </elementTextContainer>
          </element>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="34637">
                <text>Medicine</text>
              </elementText>
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        <src>https://www.socictopen.socict.org/files/original/3537303f1d0697e35e8e47f75973a917.pdf</src>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>What Does Food Retail Research Tell Us About the Implications of Coronavirus (COVID-19) for Grocery Purchasing Habits?</text>
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            </elementTextContainer>
          </element>
          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="34639">
                <text>Matthew B. Ruby, Rosemarie Martin-Neuninger</text>
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            <name>Date</name>
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                <text>2020</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>heuristics, food choice, COVID-19, grocery shopping, panic buying</text>
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            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="34642">
                <text>DOI: 10.3389/fpsyg.2020.01448</text>
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            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="34643">
                <text>Frontiers in Psychology</text>
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            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="34644">
                <text>Frontiers Media S.A.</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Psychology</text>
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                  <text>Dominio científico: Coronavirus</text>
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            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="34646">
                <text>A Novel Scoring System for Prediction of Disease Severity in COVID-19</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="34647">
                <text>Yan Zhao, Chi Zhang, Qi Wang, Xuemei Li, Ling Qin, Bin Xu, Yonghong Zhang, Ying-Mei Feng, Kang Li, Ronghua Jin, Jian-Ping Sun, Yanchao Dai, Tao Dong, Lian-Chun Liang, Zhongjie Hu, Haiping Xiang</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="34648">
                <text>Background: A novel enveloped RNA beta coronavirus, Corona Virus Disease 2019 (COVID-19) caused severe and even fetal pneumonia in China and other countries from December 2019. Early detection of severe patients with COVID-19 is of great significance to shorten the disease course and reduce mortality.Methods: We assembled a retrospective cohort of 80 patients (including 56 mild and 24 severe) with COVID-19 infection treated at Beijing You'an Hospital. We used univariable and multivariable logistic regression analyses to select the risk factors of severe and even fetal pneumonia and build scoring system for prediction, which was validated later on in a group of 22 COVID-19 patients.Results: Age, white blood cell count, neutrophil, glomerular filtration rate, and myoglobin were selected by multivariate analysis as candidates of scoring system for prediction of disease severity in COVID-19. The scoring system was applied to calculate the predictive value and found that the percentage of ICU admission (20%, 6/30) and ventilation (16.7%, 5/30) in patients with high risk was much higher than those (2%, 1/50; 2%, 1/50) in patients with low risk (p = 0.009; p = 0.026). The AUC of scoring system was 0.906, sensitivity of prediction is 70.8%, and the specificity is 89.3%. According to scoring system, the probability of patients in high risk group developing severe disease was 20.24 times than that in low risk group.Conclusions: The possibility of severity in COVID-19 infection predicted by scoring system could help patients to receiving different therapy strategies at a very early stage.Topic: COVID-19, severe and fetal pneumonia, logistic regression, scoring system, prediction.</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="34649">
                <text>2020</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="34650">
                <text>Logistic regression, retrospective cohort, COVID-19, severity pneumonia, prediction scoring system</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="34651">
                <text>DOI: 10.3389/fcimb.2020.00318</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="34652">
                <text>Frontiers in Cellular and Infection Microbiology</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="34653">
                <text>Frontiers Media S.A.</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="34654">
                <text>Microbiology</text>
              </elementText>
            </elementTextContainer>
          </element>
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