379 10 20655 https://www.socictopen.socict.org/files/original/22504b51356277929995b8f83db3190a.pdf 6cd37884d2f37af95127aee823ed402b Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Clinician-patient-family member interactions in COVID-19 serious conditions: A glimpse from the other side of the limbo. Creator An entity primarily responsible for making the resource Lidia Borghi Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource covid-19, Uncertainty, health psychology, Clinician-Patient-Family members interactions, Relationship-Centered care, Serious conditions Identifier An unambiguous reference to the resource within a given context 10.1016/j.pec.2021.02.003 Source A related resource from which the described resource is derived Patient education and counseling https://www.socictopen.socict.org/files/original/1ecc843ce124113f42c1f4ec896dc527.pdf 48dddabe1a14121070be7119ee0ea1b6 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Clinicopathological characteristics of 8697 patients with COVID-19 in China: a meta-analysis. Creator An entity primarily responsible for making the resource Hongyuan Li, Pan Ji, Chunling Zhao, Jielong Pang, Jieyun Zhu, Zhimei Zhong, Bocheng Li, Jianfeng Zhang Description An account of the resource Our study aims to present a summary of the clinicopathological characteristics of patients affected by the coronavirus disease 2019 (COVID-19) that can be used as a reference for further research and clinical decisions. Studies were included in the meta-analysis if they had cohort, case-control or case series designs and provided sufficient details on clinical symptoms, laboratory outcomes and asymptomatic patients. PubMed, Embase, Chinese Biomedical Literature Database, Wanfang, China Science and Technology Journal Database and China National Knowledge Infrastructure databases were electronically searched to identify related studies published between 1 January 2020 and 16 March 2020. Three reviewers independently examined the literature, extracted relevant data and assessed the risk of publication bias before including the studies in the meta-analysis. The confirmed cases of COVID-19. A total of 55 unique retrospective studies involving 8697 patients with COVID-19 were identified. Meta-analysis showed that a higher proportion of infected patients were male (53.3%), and the two major symptoms observed were fever (78.4%) and cough (58.3%). Other common symptoms included fatigue (34%), myalgia (21.9%), expectoration (23.7%), anorexia (22.9%), chest tightness (22.9%) and dyspnoea (20.6%). Minor symptoms included nausea and vomiting (6.6%), diarrhoea (8.2%), headache (11.3%), pharyngalgia (11.6%), shivering (15.2%) and rhinorrhea (7.3%). About 5.4% of the patients were asymptomatic. Most patients showed normal leucocyte counts (64.7%) and elevated C reactive protein levels (65.9%). Lymphopaenia was observed in about 47.6% of the infected patients, along with abnormal levels of myocardial enzymes (49.4%) and liver function (26.4%). Other findings included leucopenia (23.5%), elevated D-dimer (20.4%), elevated erythrocyte sedimentation rate (20.4%), leucocytosis (9.9%), elevated procalcitonin (16.7%) and abnormal renal function (10.9%). The most commonly experienced symptoms of patients with COVID-19 were fever and cough. Myalgia, anorexia, chest tightness and dyspnoea were found in some patients. A relatively small percentage of patients were asymptomatic and could act as carriers of the disease. Most patients showed normal leucocyte counts, elevated levels of C reactive protein and lymphopaenia, confirming the viral origin of the disease. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Communicable disease control Identifier An unambiguous reference to the resource within a given context DOI: 10.1136/fmch-2020-000406 Source A related resource from which the described resource is derived Family Medicine and Community Health Publisher An entity responsible for making the resource available BMJ Publishing Group https://www.socictopen.socict.org/files/original/a3d03f90281bb0829031c66a4d04a66a.pdf c90742e2c55f31db51d0cb57510b4923 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Cloaked similarity between HIV-1 and SARS-CoV suggests an anti-SARS strategy Creator An entity primarily responsible for making the resource Kliger Yossef, Levanon Erez Y Description An account of the resource Abstract Background Severe acute respiratory syndrome (SARS) is a febrile respiratory illness. The disease has been etiologically linked to a novel coronavirus that has been named the SARS-associated coronavirus (SARS-CoV), whose genome was recently sequenced. Since it is a member of the Coronaviridae, its spike protein (S2) is believed to play a central role in viral entry by facilitating fusion between the viral and host cell membranes. The protein responsible for viral-induced membrane fusion of HIV-1 (gp41) differs in length, and has no sequence homology with S2. Results Sequence analysis reveals that the two viral proteins share the sequence motifs that construct their active conformation. These include (1) an N-terminal leucine/isoleucine zipper-like sequence, and (2) a C-terminal heptad repeat located upstream of (3) an aromatic residue-rich region juxtaposed to the (4) transmembrane segment. Conclusions This study points to a similar mode of action for the two viral proteins, suggesting that anti-viral strategy that targets the viral-induced membrane fusion step can be adopted from HIV-1 to SARS-CoV. Recently the FDA approved Enfuvirtide, a synthetic peptide corresponding to the C-terminal heptad repeat of HIV-1 gp41, as an anti-AIDS agent. Enfuvirtide and C34, another anti HIV-1 peptide, exert their inhibitory activity by binding to a leucine/isoleucine zipper-like sequence in gp41, thus inhibiting a conformational change of gp41 required for its activation. We suggest that peptides corresponding to the C-terminal heptad repeat of the S2 protein may serve as inhibitors for SARS-CoV entry. Date A point or period of time associated with an event in the lifecycle of the resource 2003 Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/1471-2180-3-20 Source A related resource from which the described resource is derived BMC Microbiology Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology Language A language of the resource EN https://www.socictopen.socict.org/files/original/c515e5c83456d3e0ea00ece40f260019.pdf 606ee8709b3da52bcdd7e30baa35fdf6 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Cloning, Prokaryotic Soluble Expression, and Analysis of Antiviral Activity of Two Novel Feline IFN-ω Proteins Creator An entity primarily responsible for making the resource Xiaona Wang, Fengsai Li, Meijing Han, Shuo Jia, Li Wang, Xinyuan Qiao, Yanping Jiang, Wen Cui, Lijie Tang, Yijing Li, Yigang Xu Description An account of the resource Cats are becoming more popular as household companions and pets, forming close relationships with humans. Although feline viral diseases can pose serious health hazards to pet cats, commercialized preventative vaccines are lacking. Interferons (IFNs), especially type I IFNs (IFN-α, IFN-β, and interferon omega (IFN-ω)), have been explored as effective therapeutic drugs against viral diseases in cats. Nevertheless, there is limited knowledge regarding feline IFN-ω (feIFN-ω), compared to IFN-α and IFN-β. In this study, we cloned the genes encoding feIFN-ωa and feIFN-ωb from cat spleen lymphocytes. Homology and phylogenetic tree analysis revealed that these two genes belonged to new subtypes of feIFN-ω. The recombinant feIFN-ωa and feIFN-ωb proteins were expressed in their soluble forms in Escherichia coli, followed by purification. Both proteins exhibited effective anti-vesicular stomatitis virus (VSV) activity in Vero, F81 (feline kidney cell), Madin−Darby bovine kidney (MDBK), Madin−Darby canine kidney (MDCK), and porcine kidney (PK-15) cells, showing broader cross-species antiviral activity than the INTERCAT IFN antiviral drug. Furthermore, the recombinant feIFN-ωa and feIFN-ωb proteins demonstrated antiviral activity against VSV, feline coronavirus (FCoV), canine parvovirus (CPV), bovine viral diarrhea virus (BVDV), and porcine epidemic diarrhea virus (PEDV), indicating better broad-spectrum antiviral activity than the INTERCAT IFN. The two novel feIFN-ω proteins (feIFN-ωa and feIFN-ωb) described in this study show promising potential to serve as effective therapeutic agents for treating viral infections in pet cats. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource novel feline interferon omega, Gene cloning, Molecular Characteristics, soluble expression, antiviral activity Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/v12030335 Source A related resource from which the described resource is derived Viruses Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology Language A language of the resource EN https://www.socictopen.socict.org/files/original/07d01a1b63702f5f035f445e4bc395ec.pdf 606ee8709b3da52bcdd7e30baa35fdf6 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Cloning, Prokaryotic Soluble Expression, and Analysis of Antiviral Activity of Two Novel Feline IFN-ω Proteins Creator An entity primarily responsible for making the resource Shuo Jia, Yanping Jiang, Wen Cui, Li Wang, Yigang Xu, Xinyuan Qiao, Meijing Han, Yijing Li, Xiaona Wang, Fengsai Li, Lijie Tang Description An account of the resource Cats are becoming more popular as household companions and pets, forming close relationships with humans. Although feline viral diseases can pose serious health hazards to pet cats, commercialized preventative vaccines are lacking. Interferons (IFNs), especially type I IFNs (IFN-α, IFN-β, and interferon omega (IFN-ω)), have been explored as effective therapeutic drugs against viral diseases in cats. Nevertheless, there is limited knowledge regarding feline IFN-ω (feIFN-ω), compared to IFN-α and IFN-β. In this study, we cloned the genes encoding feIFN-ωa and feIFN-ωb from cat spleen lymphocytes. Homology and phylogenetic tree analysis revealed that these two genes belonged to new subtypes of feIFN-ω. The recombinant feIFN-ωa and feIFN-ωb proteins were expressed in their soluble forms in Escherichia coli, followed by purification. Both proteins exhibited effective anti-vesicular stomatitis virus (VSV) activity in Vero, F81 (feline kidney cell), Madin−Darby bovine kidney (MDBK), Madin−Darby canine kidney (MDCK), and porcine kidney (PK-15) cells, showing broader cross-species antiviral activity than the INTERCAT IFN antiviral drug. Furthermore, the recombinant feIFN-ωa and feIFN-ωb proteins demonstrated antiviral activity against VSV, feline coronavirus (FCoV), canine parvovirus (CPV), bovine viral diarrhea virus (BVDV), and porcine epidemic diarrhea virus (PEDV), indicating better broad-spectrum antiviral activity than the INTERCAT IFN. The two novel feIFN-ω proteins (feIFN-ωa and feIFN-ωb) described in this study show promising potential to serve as effective therapeutic agents for treating viral infections in pet cats. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource antiviral activity, gene cloning, molecular characteristics, soluble expression, novel feline interferon omega Identifier An unambiguous reference to the resource within a given context 10.3390/v12030335 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology https://www.socictopen.socict.org/files/original/9d98c7dff62f2b67a860b3f508b2f105.pdf 94595dddb363b458140d204d2a0ad5ea Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Clorofila e carotenoides em maracujazeiro-amarelo irrigado com águas salinas no solo com biofertilizante bovino Creator An entity primarily responsible for making the resource Lourival Ferreira Cavalcante, Thiago Jardelino Dias, Ronaldo Nascimento, José Lucínio De Oliveira Freire Description An account of the resource Os efeitos deletérios provocados pelo estresse salino resultam em modificações nos mecanismos bioquímicos e fisiológicos das plantas, alterando, dentre outros, os teores foliares de clorofila e carotenoides, comprometendo a atividade fotossintética e, consequentemente, o crescimento, o desenvolvimento, a produção e a adaptabilidade aos ambientes adversos. O objetivo do trabalho foi avaliar os efeitos de diferentes condutividades elétricas da água de irrigação (CEai), associadas às épocas de aplicação de biofertilizante, sobre os teores de pigmentos fotossintéticos para a determinação dos pigmentos cloroplastídicos (clorofila a, b, total e carotenoides) do maracujazeiro-amarelo. Os tratamentos foram distribuídos em arranjo fatorial 5 x 4, referentes aos valores de CEai: 0,5; 1,5; 2,5; 3,5 e 4,5 dS m-1, em quatro épocas de aplicação do biofertilizante: sem biofertilizante (SB); aplicação uma semana antes do transplantio (1SAT); a cada 90 dias, a partir do transplantio (90DAT); uma semana antes e a cada 90 dias, após o transplantio (1SAT+90DAT). O aumento da concentração salina da água de irrigação reduziu a eficiência fotossintética nas folhas do maracujazeiro-amarelo, sendo mais drástico na condutividade superior a 2,5 dS m-1. As frequências de aplicação do biofertilizante não influenciaram nas concentrações dos pigmentos fotossintéticos. Date A point or period of time associated with an event in the lifecycle of the resource 2011 Subject The topic of the resource Efluente orgânico, Passiflora edulis, Salinidade, pigmentos fotossintéticos Identifier An unambiguous reference to the resource within a given context 10.1590/S0100-29452011000500098 Source A related resource from which the described resource is derived Revista Brasileira de Fruticultura Publisher An entity responsible for making the resource available Sociedade Brasileira de Fruticultura Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Plant culture Relation A related resource <a href="http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-29452011000500098&lng=en&tlng=en" target="_blank" rel="noreferrer noopener">http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-29452011000500098&lng=en&tlng=en</a> https://www.socictopen.socict.org/files/original/9806e3821b5ead85f4ceca5bf32dc173.pdf f41ba1011a32fb67de2324baa9a28026 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Close Relative of Human Middle East Respiratory Syndrome Coronavirus in Bat, South Africa Creator An entity primarily responsible for making the resource Ndapewa Laudika Ithete, Samantha Stoffberg, Victor Max Corman, Veronika M. Cottontail, Leigh Rosanne Richards, M. Corrie Schoeman, Christian Drosten, Jan Felix Drexler, Wolfgang Preiser Date A point or period of time associated with an event in the lifecycle of the resource 2013 Subject The topic of the resource bats, coronavirus, MERS-CoV, Zoonoses, Viruses, South Africa Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid1910.130946 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/6182e69400cc5a874e2c4ff9178941f0.pdf d76f4ccd54b0f157c77064f87341ee51 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Clostridiodes difficile in COVID-19 Patients, Detroit, Michigan, USA, March–April 2020 Creator An entity primarily responsible for making the resource Saraswathi Lakkasani, Kok Hoe Chan, Hamid S. Shaaban Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource IFN-γ, covid-19, SARS-CoV-2, innate immunity, il-12, Clostridiodes difficile Identifier An unambiguous reference to the resource within a given context 10.3201/eid2609.202505 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine, Infectious and parasitic diseases https://www.socictopen.socict.org/files/original/6ded65d2d7804ec0af8e4933e10cbac5.pdf 8aeaf4c18c1954d3fde3aa8e7137aad4 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Clotting Factors in COVID-19: Epidemiological Association and Prognostic Values in Different Clinical Presentations in an Italian Cohort Creator An entity primarily responsible for making the resource Pierpaolo Di Micco, Vincenzo Russo, Corrado Lodigiani, Giuseppe Cardillo, Novella Carannante, Michele Imparato, Stefano Rodolfi Description An account of the resource Introduction: A novel highly pathogenic human coronavirus able to induce severe acute respiratory syndrome (SARS) has been recently recognized as the cause of the coronavirus disease 2019 (COVID-19) outbreak, which has spread rapidly from China to other countries. Little is known about laboratory prognostic markers in COVID-19 patients. The aim of our study was to describe the basic clotting parameters in COVID-19 patients and their prognostic role in different clinical forms of the disease. Material and Methods: We enrolled 67 COVID-19 patients admitted to the Emergency Department. A cohort of 67 age- and sex-matched non-COVID-19 patients with acute respiratory illness was used as a control group. For all patients, platelet count (PLT), prothrombin time (PT), activated thromboplastin time (aPTT), C-reactive protein (PCR), fibrinogen, and D-dimer were determined. The COVID-19 population was divided in two groups according to the presence or absence of SARS. The clotting factors values were compared between the groups. Results: At admission, the COVID-19 patients showed statistically significant increased levels of fibrinogen (601.5 (480–747) vs. 455 (352.5–588.5) mg/dL; p = 0.0000064), and a higher percentage of patients had fibrinogen levels >400 mg/dL (86% vs.58%; p = 0.0054) compared to the control group. The levels of fibrinogen were higher in COVID-19 patients with SARS compared to those without SARS (747 (600.0–834.0) vs. 567 (472.5–644.50); p = 0.0003). Conclusion: Fibrinogen seems to increase early in COVID-19 patients and may be used as a risk stratification marker for the early detection of a subgroup of COVID-19 patient at increased risk to develop SARS, who might benefit from a different and thorough clinical surveillance and treatment. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Fibrinogen, Prothrombin time, Disseminated intravascular coagulation, SARS-CoV-2, COVID-19, alteration of hemostasis Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/jcm9051371 Source A related resource from which the described resource is derived Journal of Clinical Medicine Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine https://www.socictopen.socict.org/files/original/933ae66d91d05d5232f48292a0a9e6a1.pdf d43d608daf57f2bb45b1672a553ce214 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource CLOUD-BASED INTEGRATION AND STANDARDIZATION OF ADDRESS DATA FOR DISASTER MANAGEMENT – A SOUTH AFRICAN CASE STUDY Creator An entity primarily responsible for making the resource G. Tredrea, S. Coetzee, V. Rautenbach Description An account of the resource Addresses are essential for disaster risk management and response because they are used to locate people affected by a disaster or at risk of being affected. South Africa is vulnerable to disasters, however, despite a legislative framework for supporting disaster risk management that meets international standards, implementation falls short due to underfunding, poor interdepartmental coordination and lack of political support. The importance of cross jurisdictional address data was highlighted by the COVID-19 pandemic of 2020 when the geocoding of positive cases was hindered due to the lack of such address data in South Africa. In this paper, we present first results about a cloud-based tool for integrating address data from multiple municipalities into a single address dataset that conforms to the South African National Standard, SANS 1883-2:2017, Geographic information – Addresses: Part 2: Address data exchange. We reviewed and evaluated three cloud platforms for the prototype implementation. The integrated dataset is maintained in the cloud and therefore readily accessible by relevant organizations. At the same time, processing in the cloud can handle changing volumes of data with elasticity, i.e. computing power can be increased or decreased at short notice, as necessary during a disaster response. Furthermore, processing can be automated, thereby mitigating the risk of reduced manpower due to a disaster. Overall, a properly maintained cloud-based tool can result in more efficient use of resources presenting a viable and interesting alternative for underfunded disaster risk management centres in South Africa and other parts of the world. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.5194/isprs-archives-XLIV-3-W1-2020-145-2020 Source A related resource from which the described resource is derived The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences Publisher An entity responsible for making the resource available Copernicus Publications Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Engineering (General). Civil engineering (General), Technology, Applied optics. Photonics