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                  <text>Dominio científico: Coronavirus</text>
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                <text>Innovative application of ultraviolet rays and hydrogen peroxide vapor for decontamination of respirators during COVID-19 pandemic- An experience from a tertiary eye care hospital</text>
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                <text>Bharat Gurnani, Rengaraj Venkatesh, Kirandeep Kaur, Rajesh Vedachalam, Joseph Gubert</text>
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                <text>2020</text>
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            <name>Identifier</name>
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                <text>10.4103/ijo.IJO_2160_20</text>
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                <text>Biotemas</text>
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                <text>Universidade Federal de Santa Catarina</text>
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                <text>Ophthalmology</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Comorbidity of COVID-19 related Fatalities in Tertiary Care Hospitals of Rawalpindi, Pakistan</text>
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            <description>An entity primarily responsible for making the resource</description>
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                <text>Rizwana Shahid, Muhammad Umar, Raja Bilal Zafar, Shazia Zeb, Saima Ambreen, Muhammad Omar Akram</text>
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                <text>Objectives: To assess the COVID-19 associated fatalities with respect to demographics, comorbidity, critical illness, and length of hospital stay in tertiary care hospitals.  Subjects &amp; Methods: A retrospective hospital data-based research was done among 216 COVID-19 associated mortalities registered in 4 tertiary care hospitals Holy Family Hospital (HFH), Benazir Bhutto Hospital (BBH), District Head Quarters Hospital (DHQ) and Rawalpindi Institute of Urology &amp; Transplantation (RIU &amp; T) affiliated with Rawalpindi Medical University from 29th March-15th June 2020. The data was gathered by consecutive sampling pertinent to demographics, hospital stay, comorbidity, critical illness, and ventilator or oxygen support. The length of hospital stay among fatalities with and without comorbidity was compared by an independent sample z-test. Data were analyzed by using SPSS version 25.0.  Results: Of the total 216 COVID-19 related mortalities, 150(69.4%) were males and 66(30.6%) were females. The mean age of fatalities was 55.66 ± 13.97 years. About 76.7% of dying males were 41-70 years old while 56.1% of females dying of COVID-19 were 41-60 years old. Most (60.8%) of study subjects had hypertension followed by diabetes (53.8%), Ischemic Heart Disease (17.5%), and respiratory disorders (12.3%). About 75% of the critically ill patients needed a ventilator for respiratory support. Length of hospital stay was determined to have a statistically insignificant association (P &gt; 0.10) with the presence or absence of comorbidity among COVID-19 patients. Critical illness had a highly significant association (P &lt; 0.000) with ventilator support among COVID-19 related mortalities.  Conclusion: People 41-70 years should preferably adopt stringent precautions for protection against COVID-19. Comorbid states chiefly hypertension, diabetes, cardiac and respiratory diseases need special consideration amid COVID-19 pandemic to abstain from adverse health outcomes.</text>
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                <text>2020</text>
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                <text>covid-19, comorbidity, diabetes, Hypertension, Ventilator, ischemic heart disease, tertiary care hospitals</text>
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            <name>Identifier</name>
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                <text>10.37939/jrmc.v24iSupp-1.1422</text>
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                <text>Journal of Rawalpindi Medical College</text>
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                <text>Rawalpindi Medical University</text>
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            <name>Coverage</name>
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                <text>Medicine</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Recent Insights into Emerging Coronavirus: SARS-CoV-2.</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="40464">
                <text>Zifang Shang, Siew Yin Chan, William J Liu, Peng Li, Wei Huang</text>
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            <description>An account of the resource</description>
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                <text>The SARS-CoV-2 outbreak that emerged at the end of 2019 has affected more than 58 million people with more than 1.38 million deaths and has had an incalculable impact on the world . Extensive prevention and treatment measures have been implemented since the pandemic. In this Review, we summarize current understanding on the source, transmission characteristics, and pathogenic mechanism of SARS-CoV-2. We also detail the recent development of diagnostic methods and potential treatment strategies of COVID-19 with focus on the ongoing clinical trials of antibodies, vaccines, and inhibitors for combating the emerging coronavirus.</text>
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                <text>2020</text>
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                <text>pathogenesis, transmission, vaccine, covid-19, Diagnosis, antibody, Pandemic, inhibitor, SARS-CoV-2, Therapy</text>
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            <name>Identifier</name>
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              <elementText elementTextId="40468">
                <text>10.1021/acsinfecdis.0c00646</text>
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            <description>A related resource from which the described resource is derived</description>
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                <text>ACS infectious diseases</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Coronavirus Disease-2019 Conundrum: RAS Blockade and Geriatric-Associated Neuropsychiatric Disorders</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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                <text>Antônio Lúcio Teixeira, Aline Silva de Miranda, Aline Silva de Miranda, Antonio Lucio Teixeira</text>
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            <description>An account of the resource</description>
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                <text>Coronavirus Disease 2019 (COVID-19) is caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which primarily targets the human respiratory system and may lead to severe pneumonia and ultimately death. Mortality rate is particurlarly high among people beyond the sixth decade of life with cardiovascular and metabolic diseases. The discovery that the SARS-CoV-2 uses the renin-angiotensin system (RAS) component ACE2 as a receptor to invade host epithelial cells and cause organs damage resulted in a debate regarding the role of ACE inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) therapies during COVID-19 pandemic. Some authors proposed the discontinuation of ACEIs and ARBs for cardiovascular, kidney, and metabolic diseases, while expert opinions have discouraged that due to limited empirical evidence of their negative effect on COVID-19 outcomes, and that withdrawing treatment may contribute to clinical decompensation in high-risk patients. Moreover, as cardiovascular and metabolic diseases are associated with neurodegenerative and psychiatric disorders, especially among older adults, a critical appraisal of the potential positive effects of ACEIs and ARBs is highly needed. Herein, we aim to discuss the conundrum of ACEIs and ARBs use in high-risk patients for COVID-19, and their potential protective role on the development and/or progression of geriatric neuropsychiatric disorders.</text>
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                <text>2020</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>covid-19, SARS-CoV-2, ACE2, ARBs, aceis, Ras</text>
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            <name>Identifier</name>
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                <text>10.3389/fmed.2020.00515</text>
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                <text>Epidemiology and Health</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>Korean Society of Epidemiology</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Medicine (General)</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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            <name>Title</name>
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                <text>Lung Ultrasound (LUS) in COVID-19 Pneumonia: Usefulness in Two Atypical Cases</text>
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            <description>An entity primarily responsible for making the resource</description>
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                <text>Vincenza Giugno, Giulia Di Marzio, Andrea Domanico, Esterita Accogli</text>
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                <text>Clinical experience and scientific articles have shown that patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be paucisymptomatic or asymptomatic at the time of diagnosis. In this paper, we will discuss two paucisymptomatic patients with blood tests suggestive for SARS-CoV-2 infection but with repeated negative nasopharyngeal swabs and without typical features of COVID-19 pneumonia on chest high-resolution computed tomography. In these cases, lung ultrasound helped to raise clinical suspicion of COVID-19 pneumonia and facilitate diagnosis.</text>
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                <text>2020</text>
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                <text>covid-19, pneumonia, lung ultrasound, Coronavirus disease 2019, nasopharyngeal swab, HRCT, LUS, High resolution computed tomography, NS</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>More than Just Pneumonia: Acute Pulmonary Embolism in Two Middle-Aged Patients with COVID-19</text>
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                <text>Jahinover Mazo, Sukhdev Singh, Zohaib Khan, Allison Foster, Ecaterina Komarnitsky, Abhiram Nagaraj, Soham Patel, Vinaya Kikkeri</text>
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                <text>Background. Although severe pneumonia and respiratory compromise have remained the predominant complications of coronavirus disease 19, we are now learning this virus is much more varied in its presentation. In particular, there are increasingly reported cases of thromboembolic events occurring in infected patients. Case Report. In this report, we present two patients, both under the age of 40 with known risk factors for venous thromboembolism, who presented with respiratory distress. Both patients were diagnosed with SARS-CoV-2 pneumonia and pulmonary embolism requiring management with anticoagulation. Both patients were discharged after a short course in the hospital. Conclusion. The discussion of a hypercoagulable state induced by coronavirus disease 19 has been well documented; however, the exact mechanisms remain unknown. We suspect that a prothrombotic inflammatory response provoked by coronavirus disease could be the culprit, acting as an additive effect on middle-aged patients with known risk factors for venous thromboembolism. We recommend clinicians closely monitor those with known risk factors for pulmonary embolism.</text>
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                <text>2020</text>
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                <text>10.1155/2020/4812036</text>
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                <text>Case Reports in Medicine</text>
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                <text>Hindawi Limited</text>
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                <text>Medicine</text>
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              <name>Title</name>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Computational View toward the Inhibition of SARS-CoV-2 Spike Glycoprotein and the 3CL Protease</text>
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                <text>Hai-Feng Ji, Zhen Qiao, Hongtao Zhang, Qian Chen</text>
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            <description>An account of the resource</description>
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                <text>Since the outbreak of the 2019 novel coronavirus disease (COVID-19), the medical research community is vigorously seeking a treatment to control the infection and save the lives of severely infected patients. The main potential candidates for the control of viruses are virally targeted agents. In this short letter, we report our calculations on the inhibitors for the SARS-CoV-2 3CL protease and the spike protein for the potential treatment of COVID-19. The results show that the most potent inhibitors of the SARS-CoV-2 3CL protease include saquinavir, tadalafil, rivaroxaban, sildenafil, dasatinib, etc. Ergotamine, amphotericin b, and vancomycin are most promising to block the interaction of the SARS-CoV-2 S-protein with human ACE-2.</text>
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                <text>2020</text>
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                <text>coronavirus, spike protein, covid-19, Protease, inhibition, computational</text>
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                <text>10.3390/computation8020053</text>
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            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="40502">
                <text>Epidemiology and Health</text>
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                <text>Korean Society of Epidemiology</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="40504">
                <text>Electronic computers. Computer science</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>SARS-CoV-2 Vaccination - An Ounce (Actually, Much Less) of Prevention.</text>
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            <name>Creator</name>
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              <elementText elementTextId="40506">
                <text>Eric J Rubin, Dan L Longo</text>
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            <name>Date</name>
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                <text>2020</text>
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            <name>Identifier</name>
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                <text>10.1056/NEJMe2034717</text>
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            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="40509">
                <text>The New England journal of medicine</text>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                <elementText elementTextId="1">
                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>[Child and adolescent depression and other mental health issues during lockdown and SARS-CoV-2/COVID-19 pandemic: A survey in school setting].</text>
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            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="40511">
                <text>Maria Castillo-Martínez, Marina Castillo-Martínez, Marc Ferrer, Sebastià González-Peris</text>
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            <name>Date</name>
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              <elementText elementTextId="40513">
                <text>10.1016/j.anpedi.2020.09.013</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="40514">
                <text>Anales de pediatria</text>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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                <text>Will the Gandhian Non-Violence Produce Nonviolence Peacekeeping: From Shanti Sena (Peace Army) to the Islamic Nonviolence</text>
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              <elementText elementTextId="40516">
                <text>Sezai OZCELİK</text>
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            <description>An account of the resource</description>
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                <text>The improvement of global security and world peace is the raison d’etre of the United Nations. The concept of multilateral peacekeeping has been practiced by the UN over the last eighty-five years. The peacekeeping operations have three main objectives: collective security, preventive diplomacy and peaceful settlement of international conflicts. The idea of creating an international nonviolence “peace army” can be traced to the Shanti Sena (Gandhian peace brigade). The members of the Shanti Sena used nonviolent unarmed tools not kill but die for their peacekeeping duties. The present study aims to shed light on the evolution of nonviolent peacekeeping ideas and present some examples in the post-Cold War conflicts.In the post-Covid-19 world, it is possible to refrain from the threat or actual use of force and replace it with unarmed civilian peacekeeping. Nonviolent peacekeeping may employ some Western (relationships, influence, advocacy, solidarity) and Islamic (sabr (patience), Hijra (exodus), fasting, umma (community), sulha (reconciliation) cultural and traditional principles and commitments. With the help of social media, citizens may become a central force for pro-democracy and anti-dictatorship movements with the emphasis of nonviolence for preventing escalation of violence and conflict early warning and early response.</text>
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                <text>2020</text>
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            <name>Subject</name>
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                <text>Peacekeeping, nonviolence, collective security</text>
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              <elementText elementTextId="40520">
                <text>Epidemiology and Health</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>Korean Society of Epidemiology</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Political science (General)</text>
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