448 10 20655 https://www.socictopen.socict.org/files/original/16f693e66fd582adb81349e705e7d9af.pdf bcb859e58f65664f8621721ed4368492 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Potential Inhibitors for Novel Coronavirus Protease Identified by Virtual Screening of 606 Million Compounds Creator An entity primarily responsible for making the resource André Fischer, Manuel Sellner, Santhosh Neranjan, Martin Smieško, Markus A. Lill Description An account of the resource The rapid outbreak of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in China followed by its spread around the world poses a serious global concern for public health. To this date, no specific drugs or vaccines are available to treat SARS-CoV-2 despite its close relation to the SARS-CoV virus that caused a similar epidemic in 2003. Thus, there remains an urgent need for the identification and development of specific antiviral therapeutics against SARS-CoV-2. To conquer viral infections, the inhibition of proteases essential for proteolytic processing of viral polyproteins is a conventional therapeutic strategy. In order to find novel inhibitors, we computationally screened a compound library of over 606 million compounds for binding at the recently solved crystal structure of the main protease (Mpro) of SARS-CoV-2. A screening of such a vast chemical space for SARS-CoV-2 Mpro inhibitors has not been reported before. After shape screening, two docking protocols were applied followed by the determination of molecular descriptors relevant for pharmacokinetics to narrow down the number of initial hits. Next, molecular dynamics simulations were conducted to validate the stability of docked binding modes and comprehensively quantify ligand binding energies. After evaluation of potential off-target binding, we report a list of 12 purchasable compounds, with binding affinity to the target protease that is predicted to be more favorable than that of the cocrystallized peptidomimetic compound. In order to quickly advise ongoing therapeutic intervention for patients, we evaluated approved antiviral drugs and other protease inhibitors to provide a list of nine compounds for drug repurposing. Furthermore, we identified the natural compounds (−)-taxifolin and rhamnetin as potential inhibitors of Mpro. Rhamnetin is already commercially available in pharmacies. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource coronavirus, virtual screening, SARS2-CoV, Computational chemistry Identifier An unambiguous reference to the resource within a given context 10.3390/ijms21103626 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General), Chemistry https://www.socictopen.socict.org/files/original/ff798f817704080e59e71777efe81040.pdf 5e6c0d34582262c20a79e37f756ecfe1 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Mental Health and the SARS-COV-2 Epidemic—Polish Research Study Creator An entity primarily responsible for making the resource Jan Chodkiewicz, Monika Talarowska, Joanna Miniszewska, Natalia Nawrocka, Przemysław Biliński Description An account of the resource Background: The aim of this study was to assess the mental state of Poles in the first weeks of the SARS-COV-2 epidemic. Methods: In the study, the General Health Questionnaire-28 (GHQ-18), The Perceived Stress Scale (PSS-10), and Mini-Cope were used. Results: The study was conducted on a group of 443 individuals, including 348 women (78.6%) and 95 men (21.4%). There were more women (χ2 = 6.42, p = 0.02) in the group of people with high results in the GHQ-28 questionnaire and the differentiating factors between those with sten scores above 7 (significantly deteriorated mental health) and those with average or low results (sten score below 7) turned out to be: treatment for mental disorders before the pandemic (χ2 = 19.57, p < 0.001) and the use of psychotherapy during the pandemic (χ2 = 4.21, p = 0.04) and psychiatric pharmacotherapy (χ2 = 8.31, p = 0.01). The presence of suicidal thoughts since the appearance of the pandemic-related restraints and limitations significantly differentiates the compared groups (χ2 = 38.48, p < 0.001). Conclusions: Every fourth person in the examined group (over 26% of the respondents) recorded results that indicate a high probability of mental functioning disorders. Approximately 10% of the respondents signalled the occurrence of suicidal thoughts since the beginning of the pandemic. The respondents complain mainly about problems in everyday life, lack of satisfaction from one’s own activities, tension, trouble sleeping, and feelings of exhaustion. Individuals with significantly reduced mental well-being use non-adaptive coping strategies, such as denying problems, emotional discharge, taking substances, discontinuation of action, and blaming themselves for the situation. The risk factors for the deterioration of the mental state of the respondents during the pandemic include psychiatric treatment before the beginning of the pandemic, the presence of suicidal thoughts during forced isolation, and the use of non-adaptive coping strategies (denial of the existence of problems, emotional discharge, use of psychoactive substances, discontinuation of action, and blaming oneself for the situation). Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource mental health, covid-19, Stress, GHQ 28 Identifier An unambiguous reference to the resource within a given context 10.3390/ijerph17197015 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine https://www.socictopen.socict.org/files/original/639501528764a497d6bbbc0e2102aad2.pdf 4097ef984f6411acacd01ef508128abc Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource What artificial intelligence may, or may not, contribute to human ARTs. Creator An entity primarily responsible for making the resource David F Albertini Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.1007/s10815-020-01962-9 Source A related resource from which the described resource is derived Journal of assisted reproduction and genetics https://www.socictopen.socict.org/files/original/3ac1be9dbf1e3c88210f6b37d84522cf.pdf 01a64de7e4e09237e35810dc2eb12a5b Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Decrease in Enteroviral Meningitis - An Unexpected Benefit of COVID-19 Mitigation? Creator An entity primarily responsible for making the resource Kami D Kies, Amber S Thomas, Matthew J Binnicker, Kelli L Bashynski, Robin Patel Description An account of the resource Enteroviral meningitis is seasonal, typically exhibiting a rise in prevalence in late summer/early fall. Based on clinical microbiology laboratory testing data of cerebrospinal fluid, the expected August/September/October peak in enteroviral meningitis did not occur in 2020, possibly related to COVID-19 mitigation strategies. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.1093/cid/ciaa1881 Source A related resource from which the described resource is derived Clinical infectious diseases : an official publication of the Infectious Diseases Society of America https://www.socictopen.socict.org/files/original/adaae816b2a3c9ff88154f6c67ca7bdb.pdf 2bb35aabbdae79182892840a6fc7402a Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Questioning COVID-19 Pre-packaged Solidarity Initiatives in the Dutch Urban Spaces Creator An entity primarily responsible for making the resource Marija Sniečkutė, Elisa Fiore Description An account of the resource The COVID-19 pandemic and subsequent lockdown has drastically transformed the urban topography and rhythms of the Dutch cities, both in the streets and when “seen from the window” (Lefebvre 1992/2004, 27). Windows and balconies, the liminal spaces where the private and public meet and depart, have become sites not only to “gaze from” but also to “gaze at”. Teddy bears, children’s drawings and letters, white T-shirts with red hearts hanging on/from the windows, as well as flags fluttering from balconies, all contributed to transforming this retracted border of cityness into a political space of communication. Similarly, the windows of commercial spaces have turned into message boards of unity and solidarity, with posters at once inviting customers to support local businesses and boosting feelings of locality... Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.5617/jea.8112 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Ethnology. Social and cultural anthropology https://www.socictopen.socict.org/files/original/9017948c53b51376ea7d4963586431a0.pdf ce7cf2da6a4f77d268f08eeddf75323f Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Public perceptions and experiences of social distancing and social isolation during the COVID-19 pandemic: a UK-based focus group study Creator An entity primarily responsible for making the resource Simon N Williams, Christopher J Armitage, Tova Tampe, Kimberly Dienes Description An account of the resource Objective This study explored UK public perceptions and experiences of social distancing and social isolation related to the COVID-19 pandemic.Design This qualitative study comprised five focus groups, carried out online during the early stages of the UK’s stay at home order (‘lockdown’), and analysed using a thematic approach.Setting Focus groups took place via online videoconferencing.Participants Participants (n=27) were all UK residents aged 18 years and older, representing a range of gender, ethnic, age and occupational backgrounds.Results Qualitative analysis revealed four main themes: (1) loss—participants’ loss of (in-person) social interaction, loss of income and loss of structure and routine led to psychological and emotional ‘losses’ such as loss of motivation, loss of meaning and loss of self-worth; (2) criticisms of government communication—participants reported a lack of trust in government and a lack of clarity in the guidelines around social distancing and isolation; (3) adherence—participants reported high self-adherence to social distancing guidelines but reported seeing or hearing of non-adherence in others; (4) uncertainty around social reintegration and the future—some participants felt they would have lingering concerns over social contact while others were eager to return to high levels of social activity.Most participants, and particularly those in low-paid or precarious employment, reported feeling that the social distancing and isolation associated with COVID-19 policy has had negative impacts on their mental health and well-being during the early stages of the UK’s ‘lockdown’.Conclusions A rapid response is necessary in terms of public health programming to mitigate the mental health impacts of COVID-19 social distancing and isolation. Social distancing and isolation ‘exit strategies’ must account for the fact that, although some individuals will voluntarily or habitually continue to socially distance, others will seek high levels of social engagement as soon as possible. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.1136/bmjopen-2020-039334 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine https://www.socictopen.socict.org/files/original/ca31a9cfe3dd8a2527d2f10ec1d8bb46.pdf f667b8f93a75af6d03ec8f33095b6e98 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Factors Related to Knowledge, Perception, and Practices Towards COVID-19 Among Patients with Autoimmune Diseases: A Multicenter Online Survey Creator An entity primarily responsible for making the resource Alvina Widhani, Iris Rengganis, Agus Joko Susanto, Eko E Surachmanto, Anshari Saifuddin Hasibuan, Deasy Fetarayani, Deshinta Putri Mulya, Nova Kurniati, Evy Yunihastuti, Raveinal Masri, Teguh Harjono Karjadi, Sukamto Koesnoe, Zuhrial Zubir, Suriani Alimudin, Riwanti Estiasari, Ahmad Yanuar Safri, Suzy Maria Description An account of the resource Background: autoimmune patients can be more susceptible to infection. Proper knowledge, perception, and practices towards COVID-19 are essential for these patients during pandemic. This study aimed to know their knowledge, perception, and practices regarding COVID-19. Methods: cross sectional study using online survey was conducted from April to May 2020. Patients with autoimmune disease were asked about demographic characteristics, diagnosis, history of treatment, knowledge, perception, and practice regarding COVID-19. Results: there were 685 respondents. Most of them were female and had systemic lupus erythematosus with median age of 37 years old. Almost all respondents had good knowledge regarding transmission of COVID-19 and did proper prevention practices. Adequacy of information and steroid or mycophenolate mofetil/mycophenolic acid (MMF/MPA) use were related to perception of the effect of pandemic to their own health. Visiting private clinic and receiving hydroxychloroquine/chloroquine sulfate or sulfasalazine were related to perception that autoimmune conditions would make them more prone to COVID-19. Work from home was related to perception that when contracting COVID-19, the symptoms would be more severe. Living in Sumatra region and getting hydroxychloroquine/chloroquine sulfate or MMF/MPA were related to perception that autoimmune medications could reduce risk of getting COVID-19. Adequate information, university education, private clinic visit, and hydroxychloroquine/chloroquine sulfate use were related to perception that COVID-19 pandemic would cause difficulties in getting medications. Conclusion: almost all respondents had good knowledge and practices regarding COVID-19. Adequacy of information, autoimmune treatment, work from home, educational background, area of living, and health care facilities contributed to perception regarding COVID-19 pandemic. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, Knowledge, Perception, practice, autoimmune Source A related resource from which the described resource is derived Acta Medica Indonesiana Publisher An entity responsible for making the resource available Interna Publishing Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Internal medicine https://www.socictopen.socict.org/files/original/33dd06803fe92d4eb031689d78ed6521.pdf 40899b42c3d83215b586114ab8985d31 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Resilience in times of global pandemic: Steering recovery and thriving trajectories. Creator An entity primarily responsible for making the resource Joana C Kuntz Description An account of the resource Disasters, including earthquakes, wildfires, terrorist attacks, and infectious disease outbreaks, are catastrophic events that expose individuals to stress, disrupt community routines and dynamics, undermine infrastructure and businesses, and result in economic losses for a significant period (Bader et al., 2019; Bakić, 2019). The World Health Organization declared the COVID-19 outbreak a pandemic in the early months of 2020 and classed it as a major disaster. This pandemic is unique, one of few catastrophic events in recent history to affect the entire global population, and its severity and long-term consequences will test individuals, organisations, communities, and nations in unprecedented ways. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.1111/apps.12296 Source A related resource from which the described resource is derived Applied psychology = Psychologie appliquee https://www.socictopen.socict.org/files/original/c84973d99c6ca6450149d6c0323f2d30.pdf 541e6b8ed8ce118145835bce5d10e2e2 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Severe Acute Respiratory Syndrome Coronavirus 2: A Protocol for Disinfection of Toothbrushes. Creator An entity primarily responsible for making the resource Júlia H Lamarca, Fabíola G de Carvalho, Fernanda C Machado, Rogério Lacerda-Santos, Taís de Souza Barbosa Date A point or period of time associated with an event in the lifecycle of the resource 2021 Identifier An unambiguous reference to the resource within a given context 10.1093/infdis/jiaa794 Source A related resource from which the described resource is derived The Journal of infectious diseases https://www.socictopen.socict.org/files/original/3856cb7337ca76618d1b5979c13408ca.pdf 5abc27a157107ed5a30065d29d0a8e83 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Guaranteeing the Health Rights of People with Disabilities in the COVID-19 Pandemic: Perspectives from China Creator An entity primarily responsible for making the resource Qi F, Wang Q Description An account of the resource Fei Qi, Qi Wang Law School, Hainan University, Haikou, Hainan Province, People&rsquo;s Republic of ChinaCorrespondence: Qi Wang Email hainan-equal-rights-research-group@outlook.comAbstract: The question of how to guarantee the health rights of people with disabilities, and their health equity in particular, is frequently neglected in infectious disease pandemics. The international response to the ongoing COVID-19 pandemic is no exception in this regard. This neglect is related to other forms of marginalization and exclusion, as people with disabilities are generally poorer and more vulnerable than their non-disabled counterparts. Sustainable Development Goal 3 lacks an appropriate human rights language that enshrines equality and inclusivity in pandemic prevention work and related policies and legislation; and, as a result, it does not sufficiently guarantee the health rights of people with disabilities. This paper draws on China&rsquo;s pandemic prevention work to extract relevant lessons, and seeks to explain how decision-making systems and resource allocation mechanisms impact on the health rights of people with disabilities. It discusses the unique roles of justice and legislation in helping to guarantee the health rights of people with disabilities in an infectious disease pandemic, and concludes that future research should more closely consider how Sustainable Development Goal 16 can support Sustainable Development Goal 3.Keywords: COVID-19, health equity, laws, infectious disease pandemic, IDP, judicature, people with disabilities, sustainable development goal, SDG Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, health equity, people with disabilities, laws, Sustainable Development Goal (SDG), judicature, infectious disease pandemic (idp) Source A related resource from which the described resource is derived Biotemas Publisher An entity responsible for making the resource available Universidade Federal de Santa Catarina Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Public aspects of medicine