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                  <text>Dominio científico: Coronavirus</text>
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                <text>Coronavirus breathing: on the implementation of remote psychological assistance during a pandemic</text>
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                <text>Dilyara N.  Efremova</text>
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                <text>In the situation, associated with the introduction of the self-isolation regime during the COVID-19 pandemic, the remote form of psychological assistance has confirmed its relevance. Features of the development of anxiety reactions in people who seek psychological help have shown the need to introduce information hygiene rules. A sense of danger and an excessive flow of information about it accelerate the development of stressful reactions in people with different levels of perception of the situation. Continual information on the topic related to mortal danger is a trigger for the development of hysteria, panic attacks, conflicts and domestic violence, disorders of the depressive spectrum and, including paradoxical behavior, a complete denial of danger.These and other issues are covered in the interview with D. N. Efremova, the practicing psychologist. Questions were asked by N. S. Kramarenko, the deputy editor-in-chief of the electronic journal Bulletin of Moscow Region State University, Doctor of Psychological sciences.</text>
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                <text>Anxiety, panic attack, psychological assistance, social and psychological support, COVID-19 pandemic, remote psychological counseling</text>
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                <text>DOI: 10.18384/2224-0209-2020-2-1004</text>
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                <text>Вестник Московского государственного областного университета</text>
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                <text>Moscow Region State University Editorial Office</text>
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                <text>Political science</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner.</text>
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                <text>Christine Burkard, Monique H. Verheije, Oliver Wicht, Sander I. van Kasteren, Frank J van Kuppeveld, Bart L. Haagmans, Lucas Pelkmans, Peter J.M. Rottier, Berend-Jan Bosch, Cornelis A.M. De Haan</text>
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                <text>Enveloped viruses need to fuse with a host cell membrane in order to deliver their genome into the host cell. While some viruses fuse with the plasma membrane, many viruses are endocytosed prior to fusion. Specific cues in the endosomal microenvironment induce conformational changes in the viral fusion proteins leading to viral and host membrane fusion. In the present study we investigated the entry of coronaviruses (CoVs). Using siRNA gene silencing, we found that proteins known to be important for late endosomal maturation and endosome-lysosome fusion profoundly promote infection of cells with mouse hepatitis coronavirus (MHV). Using recombinant MHVs expressing reporter genes as well as a novel, replication-independent fusion assay we confirmed the importance of clathrin-mediated endocytosis and demonstrated that trafficking of MHV to lysosomes is required for fusion and productive entry to occur. Nevertheless, MHV was shown to be less sensitive to perturbation of endosomal pH than vesicular stomatitis virus and influenza A virus, which fuse in early and late endosomes, respectively. Our results indicate that entry of MHV depends on proteolytic processing of its fusion protein S by lysosomal proteases. Fusion of MHV was severely inhibited by a pan-lysosomal protease inhibitor, while trafficking of MHV to lysosomes and processing by lysosomal proteases was no longer required when a furin cleavage site was introduced in the S protein immediately upstream of the fusion peptide. Also entry of feline CoV was shown to depend on trafficking to lysosomes and processing by lysosomal proteases. In contrast, MERS-CoV, which contains a minimal furin cleavage site just upstream of the fusion peptide, was negatively affected by inhibition of furin, but not of lysosomal proteases. We conclude that a proteolytic cleavage site in the CoV S protein directly upstream of the fusion peptide is an essential determinant of the intracellular site of fusion.</text>
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                <text>DOI: 10.1371/journal.ppat.1004502</text>
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                <text>PLoS Pathogens</text>
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                <text>Biology (General), Immunologic diseases. Allergy</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Coronavirus crisis and its effects on the economy</text>
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                <text>Oleg V. Buklemishev</text>
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                <text>Unlike the global financial crisis of 2007-2009, the current economic turmoil turns to be more severe and lasting being aggravated by the epidemiological uncertainties. This fact is mainly due to the specifics of the crisis in terms of its main transmission channels (via demand, supply, finance and expectations) and its likely consequences, including technological shift, varying the direction and volume of trade flows, adjustments of structural proportions and relative prices and most of all – socio-cultural change bringing about the increased role of the state and de-globalization deepening. These post-crisis effects and the uncertain prospects of recovery are considered in the article.</text>
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                <text>DOI: 10.3897/popecon.4.e53295</text>
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                <text>Население и экономика</text>
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                <text>Moscow State University, Faculty of Economics</text>
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                <text>Economic theory. Demography</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Coronavirus Disease (COVID-19–SARS-CoV-2) and Nutrition: Is Infection in Italy Suggesting a Connection?</text>
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                <text>Marcello Chieppa, Hellas Cena</text>
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                <text>Novel coronavirus disease (COVID-19) was declared a global pandemic on March 11, 2020. The outbreak first occurred in Wuhan, Hubei, China, in December 2019 and hit Italy heavily in February 2020. Several countries are adopting complete or partial lockdown to contain the growth of COVID-19 infection. These measures may affect people's mental health and well-being but are necessary to avoid spreading the pandemic. There has been a gradual increase in studies exploring prevention and control measures, and we recommend paying close attention to nutrition, which may contribute to modulating some important consequences of COVID-19 infection, as such pro-inflammatory cytokine storm.</text>
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                <text>Diabetes, nutrition, polyphenols, incidence, Cytokine storm, COVID-19</text>
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                <text>DOI: 10.3389/fimmu.2020.00944</text>
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                <text>Frontiers in Immunology</text>
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                <text>Frontiers Media S.A.</text>
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                <text>Immunologic diseases. Allergy</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Coronavirus disease (COVID-19) and disseminated intravascular coagulation syndrome</text>
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                <text>A. S. Shkoda, A. D. Makatsariya, V. O. Bitsadze, J. Kh. Khizroeva, K. N. Grigoreva, M. A. Mingalimov, M. V. Tretyakova, I. Elalamy, V. B. Nemirovskiy, D. V. Blinov, D. V. Mitryuk</text>
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          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="23244">
                <text>DOI: 10.25298/2221-8785-2020-18-2-203-210</text>
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          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="23245">
                <text>Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta</text>
              </elementText>
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          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>Grodno State Medical University</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="23247">
                <text>Medicine</text>
              </elementText>
            </elementTextContainer>
          </element>
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