454 10 20655 https://www.socictopen.socict.org/files/original/3f6fdf4fe352e2ca8732dbe625168086.pdf 8e7ed897b8a1fda6fde7f9be8741e97a Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Severe Acute Respiratory Syndrome Coronavirus 2 Outbreak Related to a Nightclub, Germany, 2020 Creator An entity primarily responsible for making the resource Nadine Muller, Mareike Kunze, Fabienne Steitz, Neil J. Saad, Barbara Mühlemann, Jörn I. Beheim-Schwarzbach, Julia Schneider, Christian Drosten, Lukas Murajda, Sandra Kochs, Claudia Ruscher, Jan Walter, Nadine Zeitlmann, Victor M. Corman Description An account of the resource We report an outbreak of coronavirus disease with 74 cases related to a nightclub in Germany in March 2020. Staff members were particularly affected (attack rate 56%) and likely caused sustained viral transmission after an event at the club. This outbreak illustrates the potential for superspreader events and corroborates current club closures. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource SARS, Respiratory Infections, covid-19, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, coronavirus disease Identifier An unambiguous reference to the resource within a given context 10.3201/eid2702.204443 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine, Infectious and parasitic diseases https://www.socictopen.socict.org/files/original/39063f7cad2ee758a19ff0e8c0b83ec9.pdf 8f11c613a9978dd4c7ed5012d821a25b Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Anti-Inflammatory Properties of Drugs Used to Control COVID-19 and their Effects on the Renin-Angiotensin System and Angiotensin-Converting Enzyme-2 Creator An entity primarily responsible for making the resource Fakhreddin Jamali, Hamed Gilzad-Kohan Description An account of the resource COVID-19 infection is associated with systemic inflammation, and sometimes hyperinflammatory responses with cytokine storm. This plays a major role in COVID-19 severity and poor disease prognosis, even death. Higher levels of inflammatory hallmarks including C-reactive protein, ferritin, D-dimers, and cytokines such as interleukin (IL) -6, IL-10 and tumor necrosis factor- α (TNF-α) have been reported. Many anti-viral drugs have been tried, but none were proven fully effective. Supportive care and management of the complications that are caused mainly by inflammation might be the key to greater survival rates and shorter hospitalization (e.g., the use of remdesivir, lopinavir, ritonavir, umifenovir (arbidol), oseltamivir, ganciclovir, favipiravir, darunavir, hydroxychloroquine, chloroquine, colchicine, azithromycin, anakinra, canakinumab, tocilizumab, siltuximab, sarilumab, Type 1 interferon, interferon β-1a, interferon α-2b, baricitinib, ruxolitinib, fedratinib, methylprednisolone and dexamethasone). However, the efficacy of these treatments still needs well-planned clinical trials. In such trials, careful attention must be paid to the duration of the treatment, the onset of beneficial effects, and the severity of the disease, otherwise, the outcomes may still remain inconclusive. Herein, we present a review of the current drugs, which are being used in the management of the disease and their anti-inflammatory properties. We also investigated if these drugs directly interact with Angiotensin-Converting Enzyme (ACE 2), which is a crucial component of the virus entry to the cells. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.18433/jpps31346 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Therapeutics. Pharmacology, Pharmacy and materia medica https://www.socictopen.socict.org/files/original/6f90d6e487af55be59e51efc7903ff38.pdf 91f16942fbb0399011292839934501c1 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Statistical design of Phase II/III clinical trials for testing therapeutic interventions in COVID-19 patients Creator An entity primarily responsible for making the resource Shesh N. Rai, Chen Qian, Jianmin Pan, Anand Seth, Deo Kumar Srivastava, Aruni Bhatnagar Description An account of the resource Abstract Background Because of unknown features of the COVID-19 and the complexity of the population affected, standard clinical trial designs on treatments may not be optimal in such patients. We propose two independent clinical trials designs based on careful grouping of patient and outcome measures. Methods Using the World Health Organization ordinal scale on patient status, we classify treatable patients (Stages 3–7) into two risk groups. Patients in Stages 3, 4 and 5 are categorized as the intermediate-risk group, while patients in Stages 6 and 7 are categorized as the high-risk group. To ensure that an intervention, if deemed efficacious, is promptly made available to vulnerable patients, we propose a group sequential design incorporating four factors stratification, two interim analyses, and a toxicity monitoring rule for the intermediate-risk group. The primary response variable (binary variable) is based on the proportion of patients discharged from hospital by the 15th day. The goal is to detect a significant improvement in this response rate. For the high-risk group, we propose a group sequential design incorporating three factors stratification, and two interim analyses, with no toxicity monitoring. The primary response variable for this design is 30 day mortality, with the goal of detecting a meaningful reduction in mortality rate. Results Required sample size and toxicity boundaries are calculated for each scenario. Sample size requirements for designs with interim analyses are marginally greater than ones without. In addition, for both the intermediate-risk group and the high-risk group, the required sample size with two interim analyses is almost identical to analyses with just one interim analysis. Conclusions We recommend using a binary outcome with composite endpoints for patients in Stage 3, 4 or 5 with a power of 90% to detect an improvement of 20% in the response rate, and a 30 day mortality rate outcome for those in Stage 6 or 7 with a power of 90% to detect 15% (effect size) reduction in mortality rate. For the intermediate-risk group, two interim analyses for efficacy evaluation along with toxicity monitoring are encouraged. For the high-risk group, two interim analyses without toxicity monitoring is advised. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource intubation, covid-19, Hospitalization, Efficacy, composite outcomes, interim analysis Identifier An unambiguous reference to the resource within a given context 10.1186/s12874-020-01101-z Source A related resource from which the described resource is derived Biotemas Publisher An entity responsible for making the resource available Universidade Federal de Santa Catarina Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine (General) https://www.socictopen.socict.org/files/original/0b9e9983e76223f34c94a1757b1dbbad.pdf 210e5f5dd93515aba952f4d858ed1316 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The Utility of Anti-Covid-19 Desks in Italy, Doubts and Criticism Creator An entity primarily responsible for making the resource Giuseppe Musumeci, Marco Bergamin Description An account of the resource As of the 14th of September, Italy has been considered one of the more susceptible nations in terms of risk of increase for Sars-Cov-2 contagion [...] Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource n/a Identifier An unambiguous reference to the resource within a given context 10.3390/jfmk6010002 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Diseases of the musculoskeletal system https://www.socictopen.socict.org/files/original/76bcea995e4c68cb6cda3b4bf29f9f33.pdf 6d608074942d20686502e65bd80510ee Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Social Transmission of Corona Virus: An overview Creator An entity primarily responsible for making the resource Somadatta Das, Angurbala Mishra, Subhasmita Biswal, Rabindra Nath Padhy, Bibhuti Bhusan Pradhan Description An account of the resource Corona virus (COVID19) causes an infectious disease of the upper respiratory tract, with terminating illness of failure of lungs. Being a viral disease, no ensconced drug for control is known and it is picked up by a new host the man as droplets in air released by a patient. The virus has been detected in 215 countries and World Health Organization (WHO) declared as an epidemic and pandemic. The common structures of social contact critically determine the spread of the infection from a patient; in the dearth of vaccines, the control of the virus has been its prevention of spread through systematic ‘social distancing measures’. Furthermore, the use of cotton facemask in public places and while dealing with one has been the robust method of prevention of spread of the virus from sneezing or talking with anyone. It was seen from January to April 2020 counties followed social distancing procedures without touching; hand-shaking or hugging with any one had least number of COVID19 affected persons. Hand washing with soap-water frequently to ward off any viral contamination obtained from touches of fomite or furniture etc., is rigorously followed, city disinfection with bleaching water has been additional practice in societies to abate infection from spits from patients in the common spaces. Moreover, the described types of social distancing framework adopted by some countries without additional measures prevented super-infection of the virus in societies. Finally, the findings have important implications for the policymaking to be adopted globally as well as, individual-scale preventive methods. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, Pandemic, social distancing, social transmission Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine (General) https://www.socictopen.socict.org/files/original/764114300e67c58e62f25a91a1b2d9ce.pdf 4f9d650035cd2a996c67edcd8d02338f Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Guidance for Facing Dilemmas of Hematopoietic Stem Cell Transplant Clinicians in the Coronavirus Disease 2019 (COVID-19) Pandemic: An Iranian Consensus Creator An entity primarily responsible for making the resource Seied Asadollah Mousavi, Soroush Rad, Tahereh Rostami, Mohammad Vaezi, Hosein Kamranzadeh, Davood Babakhani, Sahar Tavakoli, Maryam Barkhordar, Tanaz Bahri, Amirabbas Hedayatiasl, azade kiumarsi Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.4084/mjhid.2020.050 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Diseases of the blood and blood-forming organs https://www.socictopen.socict.org/files/original/695c87c622c160995023411244769821.pdf 8de757ee9166d782614e3d640b7a71bc Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Perioperative management by WeChat under the haze of COVID-19 Creator An entity primarily responsible for making the resource Yin-Hao Wang, Li-Ming Zhao, Zi-Yuan Liu, Xue-Min Li Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.18240/ijo.2020.07.22 Source A related resource from which the described resource is derived International Journal of Ophthalmology Publisher An entity responsible for making the resource available Press of International Journal of Ophthalmology (IJO PRESS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Ophthalmology https://www.socictopen.socict.org/files/original/8ff9d19b5aa00e551db00bfb12b85699.pdf 70a995d0b3445eb8e03ed54098c7476f Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Equality, Inclusion, and Diversity in Healthcare During the COVID-19 Pandemic Creator An entity primarily responsible for making the resource Jayoung Kim Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.5213/inj.2040198.099 Source A related resource from which the described resource is derived International Neurourology Journal Publisher An entity responsible for making the resource available Korean Continence Society Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Diseases of the genitourinary system. Urology https://www.socictopen.socict.org/files/original/43d0a0eeed60685ca8761fa423216e0f.pdf 9d45fc9ae9e0c918436d7e17813b3416 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Medical students in Indonesia: an invaluable living gemstone during coronavirus disease 2019 pandemic Creator An entity primarily responsible for making the resource Ardi Findyartini, Gilbert Lazarus, Ghea Mangkuliguna Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.3946/kjme.2020.165 Source A related resource from which the described resource is derived Korean Journal of Medical Education Publisher An entity responsible for making the resource available Korean Society of Medical Education Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine (General), Education (General) https://www.socictopen.socict.org/files/original/18cd53068a12d365968cc3961309b60f.pdf 93cb32dae1421dbbafc215fe10efa433 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource VLEs: A Metaphorical History from Sharks to Limpets Creator An entity primarily responsible for making the resource Eamon Costello, Tom Farrelly, Enda Donlon Description An account of the resource In this paper we chart the history of selected metaphors that have been used to describe Virtual Learning Environments (VLEs) over the last 15 years. Martin Weller famously claimed in 2007 that “the VLE is dead”. This provocation positioned the VLE as an object of history, forcing us to consider its past, present and future. This notion of historical mapping is important as many educational technologies that failed to deliver on their promises can be easily forgotten. Hence, we sought to develop a short history of VLE metaphors. Using a defined search and selection strategy we selected 30 metaphors spanning a 15-year period from 2004 to 2019 derived from a variety of sources ranging from social media to scholarly publications. We first arranged the metaphors according to a chronological timeline. Next we sought to unpack their significance by thematically analysing them using the notion of metaphorical concepts. Through this thematic analysis, six organizing metaphorical concepts were generated: Straitjacket, Behemoth, Digital Carpark, Safe Space, Smorgasbord and Pathfinder. We then used these metaphorical concepts as a lens, to map and explore historical developments and debates over the past two decades of educational technology. As the world scrambles to go online during the COVID-19 pandemic there has never been a more important time to remember and reflect upon digital learning history. Through this work we contribute to the history of educational technology by remembering its metaphors and what they have taught us. After we had navigated these historical seas, we noticed that the VLE was still here, as a limpet resolutely awaiting the next wave. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Virtual learning environments, metaphors, VLE, digital learning history Identifier An unambiguous reference to the resource within a given context 10.5334/jime.575 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Theory and practice of education