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                  <text>Dominio científico: Coronavirus</text>
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                <text>When there is a pandemic there is no time to waste: should we have hydroxychloroquine in our armoury against COVID-19 infected patients?</text>
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                <text>Dimitrios P. Bogdanos, Lazaros I. Sakkas, Zoi Daniil, Epaminondas Zakynthinos, Konstantinos Gourgoulianis</text>
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                <text>The current use of chloroquine and/or hydroxychloroquine, a drug currently used to treat autoimmune rheumatic diseases, in treating severe acute respiratory syndrome caused by coronavirus 2 (SARSCoV-2) or COVID-19-infected patients with pneumonia is a matter of intense consideration. We wish to enter the ongoing debate as to whether this well-known drug must be given to Greek COVID-19-infected patients, especially those with pneumonia. Our arguments are based on the existing data and the capacity of the Greek health system to afford potent anti-viral treatments, which are under immense investigation. We propose several suggestions related to treatment of COVID-19 pneumonia with chloroquine/hydroxychloroquine that we think must be taken into consideration to fit the evolving situation of the pandemic in Greece.</text>
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                <text>covid-19, Pandemic, Hydroxychloroquine, chloroquine</text>
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                <text>Biotemas</text>
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                <text>Universidade Federal de Santa Catarina</text>
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                <text>Diseases of the musculoskeletal system</text>
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                <text>The Effect of Anti-COVID-19 Policies on the Evolution of the Disease: A Complex Network Analysis of the Successful Case of Greece</text>
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                <text>Within the context of Greece promising a success story in the fight against the disease, this paper proposes a novel method for studying the evolution of the Greek COVID-19 infection curve in relation to the anti-COVID-19 policies applied to control the pandemic. Based on the ongoing spread of COVID-19 and the insufficient data for applying classic time-series approaches, the analysis builds on the visibility graph algorithm to study the Greek COVID-19 infection curve as a complex network. By using the modularity optimization algorithm, the generated visibility graph is divided into communities defining periods of different connectivity in the time-series body. These periods reveal a sequence of different typologies in the evolution of the disease, starting with a power pattern, where a second order polynomial (U-shaped) pattern intermediates, being followed by a couple of exponential patterns, and ending up with a current logarithmic pattern revealing that the evolution of the Greek COVID-19 infection curve tends towards saturation. In terms of Gaussian modeling, this successive compression of the COVID-19 infection curve into five parts implies that the pandemic in Greece is about to reach the second (decline) half of the bell-shaped distribution. The network analysis also illustrates stability of hubs and instability of medium and low-degree nodes, implying a low probability of meeting maximum (infection) values in the future and high uncertainty in the variability of other values below the average. The overall approach contributes to the scientific research by proposing a novel method for the structural decomposition of a time-series into periods, which allows removing from the series the disconnected past-data facilitating better forecasting, and provides insights of good policy and decision-making practices and management that may help other countries improve their performance in the war against COVID-19.</text>
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                <text>infectious disease, coronavirus, community detection, Pandemics, modularity optimization, natural visibility algorithm</text>
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                <text>DOI: 10.3390/physics2020017</text>
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                <text>Dimitrios Velissaris, Maria Lagadinou, Nicholas Zareifopoulos, Anastasia Karela, Gerasimos Karantzogiannis, Christina Platanaki</text>
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                <text>Even though the early reports from China provided advance warning of what was to come, the COVID-19 pandemic has spread throughout the world with devastating consequences. Emergency measures are being implemented to reduce the magnitude of the public health crisis, prevent healthcare facilities from becoming overwhelmed and reduce the death toll of the disease. Containment strategies to mitigate viral transmission and emergency measures to increase the capacity of each country to provide intensive care are at the forefront of the public health management of the epidemic, even though the detrimental social and psychological effects of quarantine are evident on a global scale. Optimal management of critically ill patients with COVID-19 is also unclear, and the initial suggestion for early intubation as in typical ARDS may have caused significant harm. The management of mild cases of confirmed infection is another point of controversy, as drugs which may be repurposed for COVID-19 treatment have significant, potentially irreversible toxic effects and their use in mild cases of a viral illness which is typically self-limited may be harmful.</text>
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                <text>mechanical ventilation, chloroquine, Critical care, SARS-CoV-2, COVID-19</text>
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                <text>DOI: 10.4081/monaldi.2020.1342</text>
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                <text>Monaldi Archives for Chest Disease</text>
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                <text>Language, information and the virtual space were distinctive features of the previous generation. Craft, matter and the fusion of the digital and the material are defining generation M, the first generation of the 21st century.</text>
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                <text>&lt;a href="http://revistas.ucm.es/index.php/TEKN/article/view/48166" target="_blank" rel="noreferrer noopener"&gt;http://revistas.ucm.es/index.php/TEKN/article/view/48166&lt;/a&gt;</text>
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                <text>Dina Maria Martins Ferreira</text>
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                <text>Este artículo discute la manifestación de lo femenino en proceso electoral brasileño. El discurso mediático nos da pistas que indican cómo lo femenino se convierte en instrumento político en un momento de decisión electoral. En dicho discurso se usan nominaciones simbólicas en juegos designativos, de tal forma que el símbolo no llega a consolidarse, sino que está al servicio del momento performativo. Las políticas de representación son constituidas paradójicamente: la naturaleza duradera del símbolo sirve al momento, los performativos se nutren de representaciones. El sistema simbólico, indicativo de cristalizaciones socioculturales, no se resiste a lo político del lenguaje y pasa a ser un recurso performativo de identidad de lo femenino.</text>
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                <text>2016</text>
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                <text>Cuestiones de Género: de la Igualdad y la Diferencia</text>
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                <text>Universidad de León</text>
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                <text>Women. Feminism</text>
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                <text>&lt;a href="http://revpubli.unileon.es/ojs/index.php/cuestionesdegenero/article/view/3575" target="_blank" rel="noreferrer noopener"&gt;http://revpubli.unileon.es/ojs/index.php/cuestionesdegenero/article/view/3575&lt;/a&gt;</text>
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                <text>The COVID-19 Cytokine Storm; What We Know So Far</text>
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                <text>COVID-19 is a rapidly spreading global threat that has been declared as a pandemic by the WHO. COVID-19 is transmitted via droplets or direct contact and infects the respiratory tract resulting in pneumonia in most of the cases and acute respiratory distress syndrome (ARDS) in about 15 % of the cases. Mortality in COVID-19 patients has been linked to the presence of the so-called “cytokine storm” induced by the virus. Excessive production of proinflammatory cytokines leads to ARDS aggravation and widespread tissue damage resulting in multi-organ failure and death. Targeting cytokines during the management of COVID-19 patients could improve survival rates and reduce mortality.</text>
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                <text>Epidemiology and Health</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Immunologic diseases. Allergy</text>
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                  <text>Agricultura sostenible</text>
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                <text>Sistema integrado de monitoreo inalámbrico de variables agroambientales en un cultivo de tomate para la generación de mapas de intensidad</text>
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                <text>Dinael Guevara-Ibarra, Julieth Estefania Gutierrez- Lopera, Johan Andrés Toloza-Rangel, Ángelo Joseph Soto-Vergel, Oriana Alexandra López-Bustamante</text>
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                <text>En este trabajo se presenta el diseño y construcción de un sistema integrado de monitoreo inalámbrico para la generación de mapas de intensidad enfocado en la agricultura de precisión empleando una metodología de cuatro etapas: análisis general, construcción, desarrollo del software y, validación y gestión de cambios. El sistema cuenta con la instrumentación para medir dióxido de carbono, temperatura, radiación ultravioleta y humedad del aire y suelo; además, implementa un sistema de posicionamiento global que permite la creación de los mapas. Los datos se envían a través del protocolo LoRaWAN a una interfaz gráfica para visualizar el comportamiento de cada variable y generar los mapas; la cual se construye bajo las necesidades particulares de un cultivo de tomate. Finalmente, se obtiene un sistema adaptable para analizar a detalle las condiciones agroambientales, facilitando la toma de decisiones del agricultor.</text>
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                <text>2021</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>Interfaz gráfica, LoRaWAN, agricultura de precisión, condiciones agroambientales, mapa de intensidad, sistema de instrumentación</text>
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                <text>Revista UIS Ingenierías</text>
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                <text>Universidad Industrial de Santander</text>
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                <text>Engineering (General). Civil engineering (General), Technology</text>
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                <text>&lt;a href="https://revistas.uis.edu.co/index.php/revistauisingenierias/article/view/11365" target="_blank" rel="noreferrer noopener"&gt;https://revistas.uis.edu.co/index.php/revistauisingenierias/article/view/11365&lt;/a&gt;</text>
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                <text>Integrando a extensão universitária ao ensino e à pesquisa em Administração: sistematização de experiência junto a indígenas à luz dos Objetivos do Desenvolvimento Sustentável</text>
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                <text>Dinara Leslye Macedo Calazans, Washington José de Souza, Nila Patrícia Freire Pequeno, Fábio Resende Araújo, Valdi de Lima Júnior</text>
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                <text>Este estudo aborda os desafios da integração da pesquisa e ensino, a partir da extensão universitária, como uma estratégia importante para materializar a qualidade da formação acadêmica em Administração em direção aos objetivos do desenvolvimento sustentável (ODS). A ação de extensão, objeto de estudo, é desenvolvida pelo Departamento de Ciências Administrativas e Departamento de Administração Pública e Gestão Social da UFRN em colaboração com outros departamentos e campi da mesma instituição. O desenvolvimento da ação se deu na Associação da comunidade indígena dos Mendonça do Amarelão, no município de João Câmara/RN. Objetivou-se, a partir da ação de extensão desenvolvida, compreender como as situações-problemas são formuladas para parceira universidade-sociedade em busca do desenvolvimento sustentável via projetos de pesquisa, e como essas ações retroalimentam o sistema de ensino. A investigação ocorreu por meio da pesquisa-ação (THIOLLENT, 2003) e abordagem qualitativa na análise dos dados. A sistematização dos problemas e necessidades comuns (comunidade-universidade) levou a um tema central sob o qual foi construída a ação: a gestão de circuitos curtos de produção, com ênfase a alcançar a soberania e segurança alimentar e nutricional, promover a agricultura sustentável e assegurar padrões de produção e de consumo sustentáveis. Percebeu-se que a comunidade é orientada para a valorização, reconhecimento e preservação dos recursos locais, importante à efetivação dos ODS. Neste sentido, além da própria condição dos povos indígenas, como aquelas relacionadas ao território, há entraves locais relacionados à gestão da capacidade produtiva e organização da produção, burocráticos, comerciais e de gênero, que impactam na sua segurança e soberania alimentar e exigiram debate interdisciplinar, com vários campos do saber, e docentes envolvidos com as necessidades atuais da sociedade para alinhá-las ao ambiente de ensino e com questões de investigação na proposição de encaminhamentos necessárias ao desenvolvimento técnico-cientifico e cultural e à formação cidadã do graduando da UFRN, destacando a atividade de extensão como elo integrador entre a pesquisa e o ensino, e possibilitando a construção de uma proposta interdisciplinar unificada que reconhece a educação como uma prática emancipatória e contínua do ser humano.</text>
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                <text>Agricultura Familiar, Desenvolvimento sustentável, Ensino e Pesquisa em Administração, Extensão Universitária, Povos indígenas</text>
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                <text>Administração: Ensino e Pesquisa</text>
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                <text>Associação Nacional dos Cursos de Graduação em Administração</text>
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                <text>Dinesh V. Jillella, Nicholas J. Janocko, Fadi Nahab, Karima Benameur, James G. Greene, Wendy L. Wright, Mahmoud Obideen, Srikant Rangaraju, Muhammad Adrish</text>
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                <text>Objective In the setting of the Coronavirus Disease 2019 (COVID-19) global pandemic caused by SARS-CoV-2, a potential association of this disease with stroke has been suggested. We aimed to describe the characteristics of patients who were admitted with COVID-19 and had an acute ischemic stroke (AIS). Methods This is a case series of PCR-confirmed COVID-19 patients with ischemic stroke admitted to an academic health system in metropolitan Atlanta, Georgia (USA) between March 24th, 2020 and July 17th, 2020. Demographic, clinical, and radiographic characteristics were described. Results Of 396 ischemic stroke patients admitted during this study period, 13 (2.5%) were also diagnosed with COVID-19. The mean age of patients was 61.6 ± 10.8 years, 10 (76.9%) male, 8 (61.5%) were Black Americans, mean time from last normal was 4.97 ± 5.1 days, and only one received acute reperfusion therapy. All 13 patients had at least one stroke-associated co-morbidity. The predominant pattern of ischemic stroke was embolic with 4 explained by atrial fibrillation. COVID-19 patients had a significantly higher rate of cryptogenic stroke than non-COVID-19 patients during the study period (69% vs 17%, p = 0.0001). Conclusions In our case series, ischemic stroke affected COVID-19 patients with traditional stroke risk factors at an age typically seen in non-COVID populations, and mainly affecting males and Black Americans. We observed a predominantly embolic pattern of stroke with a higher than expected rate of cryptogenic strokes, a prolonged median time to presentation and symptom recognition limiting the use of acute reperfusion treatments. These results highlight the need for increased community awareness, early identification, and management of AIS in COVID-19 patients.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2020</text>
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          <element elementId="48">
            <name>Source</name>
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                <text>Epidemiology and Health</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="40012">
                <text>Korean Society of Epidemiology</text>
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            </elementTextContainer>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Science, Medicine</text>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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          <element elementId="50">
            <name>Title</name>
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                <text>Recent Progress in Studies of Arterivirus- and Coronavirus-Host Interactions</text>
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                <text>Ding Xiang Liu, Yanxin Zhong, Yong Wah Tan</text>
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            <description>An account of the resource</description>
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                <text>Animal coronaviruses, such as infectious bronchitis virus (IBV), and arteriviruses, such as porcine reproductive and respiratory syndrome virus (PRRSV), are able to manifest highly contagious infections in their specific native hosts, thereby arising in critical economic damage to animal industries. This review discusses recent progress in studies of virus-host interactions during animal and human coronavirus and arterivirus infections, with emphasis on IBV-host cell interactions. These interactions may be directly involved in viral replication or lead to the alteration of certain signaling pathways, such as cell stress response and innate immunity, to facilitate viral replication and pathogenesis.</text>
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                <text>2012</text>
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            <name>Subject</name>
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                <text>virus-host interactions, coronavirus, arterivirus</text>
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                <text>DOI: 10.3390/v4060980</text>
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          <element elementId="48">
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                <text>Viruses</text>
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                <text>MDPI AG</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Microbiology</text>
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                <text>EN</text>
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