52 10 20655 https://www.socictopen.socict.org/files/original/0df8ef8ba090bdb8e87fbd141e15a92a.pdf fb7dbc70069c77fc0eced16aa734221e Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Synthesis, Molecular Properties Estimations, and Dual Dopamine D2 and D3 Receptor Activities of Benzothiazole-Based Ligands Creator An entity primarily responsible for making the resource Moritz Schübler, Bassem Sadek, Tim Kottke, Lilia Weizel, Holger Stark Description An account of the resource Neurleptic drugs, e.g., aripiprazole, targeting the dopamine D2S and D3 receptors (D2SR and D3R) in the central nervous system are widely used in the treatment of several psychotic and neurodegenerative diseases. Therefore, a new series of benzothiazole-based ligands (3-20) was synthesized by applying the bioisosteric approach derived from the selective D3Rs ligand BP-897 (1) and its structurally related benz[d]imidazole derivative (2). Herein, introduction of the benzothiazole moiety was well tolerated by D2SR and D3R binding sites leading to antagonist affinities in the low nanomolar concentration range at both receptor subtypes. However, all novel compounds showed lower antagonist affinity to D3R when compared to that of 1. Further exploration of different substitution patterns at the benzothiazole heterocycle and the basic 4-phenylpiperazine resulted in the discovery of high dually acting D2SR and D3R ligands. Moreover, the methoxy substitution at 2-position of 4-phenylpiperazine resulted in significantly (22-fold) increased D2SR binding affinity as compared to the parent ligand 1, and improved physicochemical and drug-likeness properties of ligands 3-11. However, the latter structural modifications failed to improve the drug-able properties in ligands having un-substituted 4-phenylpiperazine analogs (12-20). Accordingly, compound 9 showed in addition to high dual affinity at the D2SR and D3R [Ki (hD2SR) = 2.8 ± 0.8 nM; Ki (hD3R) = 3.0 ± 1.6 nM], promising clogS, clogP, LE (hD2SR, hD3R), LipE (hD2SR, hD3R), and drug-likeness score values of −4.7, 4.2, (0.4, 0.4), (4.4, 4.3), and 0.7, respectively. Also, the deaminated analog 10 [Ki (hD2SR) = 3.2 ± 0.4 nM; Ki (hD3R) = 8.5 ± 2.2 nM] revealed clogS, clogP, LE (hD2SR, hD3R), LipE (hD2SR, hD3R) and drug-likeness score values of −4.7, 4.2, (0.4, 0.4), (3.9, 3.5), and 0.4, respectively. The results observed for the newly developed benzothiazole-based ligands 3-20 provide clues for the diversity in structure activity relationships (SARs) at the D2SR and D3R subtypes. Date A point or period of time associated with an event in the lifecycle of the resource 2017 Subject The topic of the resource benzothiazoles, dopamine D2S/D3 receptor, in vitro activities, privileged structures, drug-likeness Identifier An unambiguous reference to the resource within a given context DOI: 10.3389/fchem.2017.00064 Source A related resource from which the described resource is derived Frontiers in Chemistry Publisher An entity responsible for making the resource available Frontiers Media S.A. Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Chemistry Language A language of the resource EN https://www.socictopen.socict.org/files/original/edc06a871b77b7070e7fae2bcd883f08.pdf 59ca3c44a616af0debf8fd7e6ae6ebc8 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Epimeria of the Southern Ocean with notes on their relatives (Crustacea, Amphipoda, Eusiroidea) Creator An entity primarily responsible for making the resource Cédric d'Udekem d'Acoz, Marie L. Verheye Description An account of the resource The present monograph includes general systematic considerations on the family Epimeriidae, a revision of the genus Epimeria Costa in Hope, 1851 in the Southern Ocean, and a shorter account on putatively related eusiroid taxa occurring in Antarctic and sub-Antarctic seas. The former epimeriid genera Actinacanthus Stebbing, 1888 and Paramphithoe Bruzelius, 1859 are transferred to other families, respectively to the Acanthonotozomellidae Coleman & J.L. Barnard, 1991 and the herein re-established Paramphithoidae G.O. Sars, 1883, so that only Epimeria and Uschakoviella Gurjanova, 1955 are retained within the Epimeriidae Boeck, 1871. The genera Apherusa Walker, 1891 and Halirages Boeck, 1891, which are phylogenetically close to Paramphithoe, are also transferred to the Paramphithoidae. The validity of the suborder Senticaudata Lowry & Myers, 2013, which conflicts with traditional and recent concepts of Eusiroidea Stebbing, 1888, is questioned. Eight subgenera are recognized for Antarctic and sub-Antarctic species of the genus Epimeria: Drakepimeria subgen. nov., Epimeriella K.H. Barnard, 1930, Hoplepimeria subgen. nov., Laevepimeria subgen. nov., Metepimeria Schellenberg, 1931, Pseudepimeria Chevreux, 1912, Subepimeria Bellan-Santini, 1972 and Urepimeria subgen. nov. The type subgenus Epimeria, as currently defined, does not occur in the Southern Ocean. Drakepimeria species are superficially similar to the type species of the genus Epimeria: E. cornigera (Fabricius, 1779), but they are phylogenetically unrelated and substantial morphological differences are obvious at a finer level. Twenty-seven new Antarctic Epimeria species are described herein: Epimeria (Drakepimeria) acanthochelon subgen. et sp. nov., E. (D.) anguloce subgen. et sp. nov., E. (D.) colemani subgen. et sp. nov., E. (D.) corbariae subgen. et sp. nov., E. (D.) cyrano subgen. et sp. nov., E. (D.) havermansiana subgen. et sp. nov., E. (D.) leukhoplites subgen. et sp. nov., E. (D.) loerzae subgen. et sp. nov., E. (D.) pandora subgen. et sp. nov., E. (D.) pyrodrakon subgen. et sp. nov., E. (D.) robertiana subgen. et sp. nov., Epimeria (Epimeriella) atalanta sp. nov., Epimeria (Hoplepimeria) cyphorachis subgen. et sp. nov., E. (H.) gargantua subgen. et sp. nov., E. (H.) linseae subgen. et sp. nov., E. (H.) quasimodo subgen. et sp. nov., E. (H.) xesta subgen. et sp. nov., Epimeria (Laevepimeria) anodon subgen. et sp. nov., E. (L.) cinderella subgen. et sp. nov., Epimeria (Pseudepimeria) amoenitas sp. nov., E. (P.) callista sp. nov., E. (P.) debroyeri sp. nov., E. (P.) kharieis sp. nov., Epimeria (Subepimeria) adeliae sp. nov., E. (S.) iota sp. nov., E. (S.) teres sp. nov. and E. (S.) urvillei sp. nov. The type specimens of E. (D.) macrodonta Walker, 1906, E. (D.) similis Chevreux, 1912, E. (H.) georgiana Schellenberg, 1931 and E. (H.) inermis Walker, 1903 are re-described and illustrated. Besides the monographic treatment of Epimeriidae from the Southern Ocean, a brief overview and identification keys are given for their putative and potential relatives from the same ocean, i.e., the Antarctic and sub-Antarctic members of the following eusiroid families: Acanthonotozomellidae Coleman & J.L. Barnard, 1991, Dikwidae Coleman & J.L. Barnard, 1991, Stilipedidae Holmes, 1908 and Vicmusiidae Just, 1990. This overview revealed the existence of a new large and characteristic species of Alexandrella Chevreux, 1911, A. chione sp. nov. but also shows that the taxonomy of that genus remains poorly known and that several ‘variable widespread eurybathic species’ probably are species complexes. Furthermore, the genera Bathypanoploea Schellenberg, 1939 and Astyroides Birstein & Vinogradova, 1960 are considered to be junior synonyms of Alexandrella. Alexandrella mixta Nicholls, 1938 and A. pulchra Ren in Ren & Huang, 1991 are re-established herein, as valid species. It is pointed out that this insufficient taxonomic knowledge of Antarctic amphipods impedes ecological and biogeographical studies requiring precise identifications. Stacking photography was used for the first time to provide iconographic support in amphipod taxonomy, and proves to be a rapid and efficient illustration method for large tridimensionally geometric species. A combined morphological and molecular approach was used whenever possible for distinguishing Epimeria species, which were often very similar (albeit never truly cryptic) and sometimes exhibited allometric and individual variations. However in several cases, taxa were characterized by morphology only, whenever the specimens available for study were inappropriately fixed or when no sequences could be obtained. A large number of Epimeria species, formerly considered as eurybathic and widely distributed, proved to be complexes of species, with a narrower (overlapping or not) distribution. The distributional range of Antarctic Epimeria is very variable from species to species. Current knowledge indicates that some species from the Scotia Arc and the tip of the Antarctic Peninsula are narrow range endemics, sometimes confined to one island, archipelago, or ridge (South Georgia, South Orkney Islands, Elephant Island or Bruce Ridge); other species have a distribution encompassing a broader region, such as the eastern shelf of the Weddell Sea, or extending from the eastern shelf of the Weddell Sea to Adélie Coast. The most widely distributed species are E. (D.) colemani subgen. et sp. nov., E. (E.) macronyx (Walker, 1906), E. (H.) inermis Walker, 1903 and E. (L.) walkeri (K.H. Barnard, 1930), which have been recorded from the Antarctic Peninsula/South Shetland Islands area to the western Ross Sea. Since restricted distributions are common among Antarctic and sub-Antarctic Epimeria, additional new species might be expected in areas such as the Kerguelen Plateau, eastern Ross Sea, Amundsen Sea and the Bellingshausen Sea or isolated seamounts and ridges, where there are currently no Epimeria recorded. The limited distribution of many Epimeria species of the Southern Ocean is presumably related to the poor dispersal capacity in most species of the genus. Indeed with the exception of the pelagic and semi-pelagic species of the subgenus Epimeriella, they are heavy strictly benthic organisms without larval stages, and they have no exceptional level of eurybathy for Antarctic amphipods. Therefore, stretches deeper than 1000 m seem to be efficient geographical barriers for many Epimeria species, but other isolating factors (e.g., large stretches poor in epifauna) might also be at play. The existence of endemic shelf species with limited dispersal capacities in the Southern Ocean (like many Epimeria) suggests the existence of multiple ice-free shelf or upper slope refugia during the Pleistocene glaciations within the distributional and bathymetric range of these species. Genera with narrow range endemics like Epimeria would be excellent model taxa for locating hotspots of Antarctic endemism, and thus potentially play a role in proposing meaningful Marine Protected Areas (MPAs) in the Southern Ocean. Date A point or period of time associated with an event in the lifecycle of the resource 2017 Subject The topic of the resource Alexandrella, Amphipoda, Epimeria, Eusiroidea, Senticaudata, Southern Ocean Identifier An unambiguous reference to the resource within a given context DOI: 10.5852/ejt.2017.359 Source A related resource from which the described resource is derived European Journal of Taxonomy Publisher An entity responsible for making the resource available Consortium of European Natural History Museums Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Botany, Zoology Language A language of the resource EN https://www.socictopen.socict.org/files/original/3c15423c19ebd238716172c1d7d28f92.pdf 34b1bf4ef6ad0e9e89fc8b0f3e6c46cb Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Sobre a evolução do vírus da bronquite infecciosa das galinhas em células VERO Creator An entity primarily responsible for making the resource Paulo Eduardo Brandão, Leonardo José Richtzenhain, Laura Yaneth Villarreal Buitrago Description An account of the resource O vírus da bronquite infecciosa das galinhas (IBV) (Nidovirales: Coronaviridae) é um Gammacoronavirus com a maior taxa evolutiva no gênero e, apesar de uma recentemente relatada atividade corretiva de sua polimerase, a diversidade intra e inter-hospedeiros é um fenômeno bem documentado. Este estudo objetivou avaliar a variação genética após passagens seriais de uma amostra de IBV variante. A amostra CRG-BETA, propagada em embriões de galinhas, foi inoculada em monocamadas de células VERO até a quarta passagem e cada passagem foi monitorada com uma RTPCR para a região S1 do gene S (nt 705 a 1094) e uma RT-PCR para o mRNA da proteína 5a do vírus. Todas as passagens foram positivas para S1 e as passagens 1 a 3 para mRNA 5a; sequências de S1 não apresentaram polimorfismos. O encontro de mRNA de IBV nos cultivos celulares demonstra que a amostra CRG-BETA está replicando nas células VERO e, em relação à análise de S1, a ausência de mutações de nucleotídeos demonstra que a amostra CRG-BETA pode ter atingido um estado fixo. Como conclusão, diferentes genótipos de IBV apresentam diferentes padrões evolutivos não apenas in vivo, como previamente conhecido, mas também in vitro, como aqui relatado. Date A point or period of time associated with an event in the lifecycle of the resource 2012 Subject The topic of the resource IBV, Espícula, evolução, in vitro Identifier An unambiguous reference to the resource within a given context DOI: 10.11606/issn.2318-3659.v49i5p386-390 Source A related resource from which the described resource is derived Brazilian Journal of Veterinary Research and Animal Science Publisher An entity responsible for making the resource available Universidade de São Paulo Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Animal culture Language A language of the resource EN, PT https://www.socictopen.socict.org/files/original/0dc09ce27749743f2b7c07a6778a5376.pdf fc9a9f17b8cab06e44254e65f513c69c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource PlasmidSeeker: identification of known plasmids from bacterial whole genome sequencing reads Creator An entity primarily responsible for making the resource Märt Roosaare, Mikk Puustusmaa, Märt Möls, Mihkel Vaher, Maido Remm Description An account of the resource Background Plasmids play an important role in the dissemination of antibiotic resistance, making their detection an important task. Using whole genome sequencing (WGS), it is possible to capture both bacterial and plasmid sequence data, but short read lengths make plasmid detection a complex problem. Results We developed a tool named PlasmidSeeker that enables the detection of plasmids from bacterial WGS data without read assembly. The PlasmidSeeker algorithm is based on k-mers and uses k-mer abundance to distinguish between plasmid and bacterial sequences. We tested the performance of PlasmidSeeker on a set of simulated and real bacterial WGS samples, resulting in 100% sensitivity and 99.98% specificity. Conclusion PlasmidSeeker enables quick detection of known plasmids and complements existing tools that assemble plasmids de novo. The PlasmidSeeker source code is stored on GitHub: https://github.com/bioinfo-ut/PlasmidSeeker. Date A point or period of time associated with an event in the lifecycle of the resource 2018 Subject The topic of the resource Plasmid, k-mer, whole genome sequencing, Unassembled Identifier An unambiguous reference to the resource within a given context DOI: 10.7717/peerj.4588 Source A related resource from which the described resource is derived PeerJ Publisher An entity responsible for making the resource available PeerJ Inc. Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/f80ab367bbf21d5814e9d6247015238f.pdf 5c012a6826823ea5273dd68e7dbd7178 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Redescription and taxonomic notes on Cyclops bohater Koźmiński, 1933 and Cyclops lacustris G.O. Sars, 1863 (Arthropoda, Crustacea), with an identification key to the Cyclops species of Fenno-Scandinavia Creator An entity primarily responsible for making the resource Maria Hołyńska, Inta Dimante-Deimantovica Description An account of the resource The studies of Cyclops O.F. Müller, 1776 have more than two centuries of tradition in Fenno-Scandinavia, yet, basic taxonomic questions remain unresolved and the limits of the distributional area are very poorly understood in the majority of the taxa (11+) occurring in the region. Based on the types and other materials we redescribe two species, C. lacustris G.O. Sars, 1863 and C. bohater Koźmiński, 1933, the latter being reported here for the first time from Fenno-Scandinavia; lectotypes of both species have been designated herein. Setulation characters of the antennal coxobasis- and maxillulary palp setae and P1 medial spine, as well as the spine formula of the terminal exopodal segments of the swimming legs (3433) in the adult female distinguish C. lacustris and C. bohater from their congeners. An identification key is provided to the Cyclops species of Fenno-Scandinavia, including information about both the female and male morphology. Although the limited material does not allow us to define the species range limits, our data nevertheless support a Northern European distribution in C. lacustris, and Northern and Central European distribution in C. bohater, while the records from the southern Palearctic need further verification. Date A point or period of time associated with an event in the lifecycle of the resource 2016 Subject The topic of the resource Cyclopidae, morphology, zoogeography, freshwater, Europe Identifier An unambiguous reference to the resource within a given context DOI: 10.5852/ejt.2016.212 Source A related resource from which the described resource is derived European Journal of Taxonomy Publisher An entity responsible for making the resource available Consortium of European Natural History Museums Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Botany, Zoology Language A language of the resource EN https://www.socictopen.socict.org/files/original/a2819fe98f5b86fe925dbcd1b4cd3967.pdf 85a477e2a00ddd3799943987a74b5fdc Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Never Let a Crisis Go to Waste: Recruiting the Next Generation of Infectious Diseases Physicians Creator An entity primarily responsible for making the resource Curtis J. Donskey Description An account of the resource Sometimes infectious diseases can seem to be the least interesting subspecialty of internal medicine. We don’t offer lifesaving or pain-relieving procedures. We offer the same advice over and over again hoping someday it might stick: wash your hands; stop prescribing antibiotics when there is no evidence of infection; and take your flu shot—it really won’t give you the flu. We give advice that some consider expendable. Shouldn’t all physicians be able to prescribe antibiotics with a little help from an online textbook or computer app? On top of all that, we apparently aren’t very stylish. One of my female colleagues recently told me she can pick out all of the male infectious disease physicians at scientific meetings by the standard uniform of ill-fitting khakis and button-down shirts. But a new crisis is always lurking to remind us that infectious diseases can be one of the most interesting and challenging areas of medicine. Emerging infections—often exotic and frightening—grab the attention of everyone from frontline personnel to the news media: Legionnaires’ disease; HIV; West Nile virus; SARS; MERS; chikungunya; Ebola virus; Zika virus; and Mycobacterium chimaera to name just a few. Without warning, common pathogens create havoc when they acquire new resistance mechanisms or virulence factors: multidrug-resistant gram-negative bacilli; Staphylococcus aureus; and Clostridium difficile. Standard procedures such as transrectal biopsy of the prostate and endoscopic retrograde cholangiopancreatography suddenly become risky due to increasing antimicrobial resistance or inadequate methods for device reprocessing. Date A point or period of time associated with an event in the lifecycle of the resource 2017 Subject The topic of the resource infectious diseases, emerging infections, antibiotics, subspecialty, National Resident Matching Program, fellowship program Identifier An unambiguous reference to the resource within a given context DOI: 10.20411/pai.v2i2.197 Source A related resource from which the described resource is derived Pathogens and Immunity Publisher An entity responsible for making the resource available Case Western Reserve University Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Pathology, Immunologic diseases. Allergy Language A language of the resource EN https://www.socictopen.socict.org/files/original/514e047cf77ca5751be38abf612bdda5.pdf fb8a04707e757a3e2316d0cfef755d4f Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Regulation of Stress Responses and Translational Control by Coronavirus Creator An entity primarily responsible for making the resource To Sing Fung, Ying Liao, Ding Xiang Liu Description An account of the resource Similar to other viruses, coronavirus infection triggers cellular stress responses in infected host cells. The close association of coronavirus replication with the endoplasmic reticulum (ER) results in the ER stress responses, which impose a challenge to the viruses. Viruses, in turn, have come up with various mechanisms to block or subvert these responses. One of the ER stress responses is inhibition of the global protein synthesis to reduce the amount of unfolded proteins inside the ER lumen. Viruses have evolved the capacity to overcome the protein translation shutoff to ensure viral protein production. Here, we review the strategies exploited by coronavirus to modulate cellular stress response pathways. The involvement of coronavirus-induced stress responses and translational control in viral pathogenesis will also be briefly discussed. Date A point or period of time associated with an event in the lifecycle of the resource 2016 Subject The topic of the resource coronavirus, ER stress, Unfolded Protein Response, p38, JNK, eIF2α, PKR, p-ERK, GADD34/PP1, nsp1, translational control Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/v8070184 Source A related resource from which the described resource is derived Viruses Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology Language A language of the resource EN https://www.socictopen.socict.org/files/original/acc0e491e79f5a74d050b9897fe63a08.pdf fe1eb9a3c2bbc4beb685b357fa8c1560 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Enantioseparation Using Cellulose Tris(3,5-dimethylphenylcarbamate) as Chiral Stationary Phase for HPLC: Influence of Molecular Weight of Cellulose Creator An entity primarily responsible for making the resource Yuji Okada, Chiyo Yamamoto, Masami Kamigaito, Yuan Gao, Jun Shen, Yoshio Okamoto Description An account of the resource The cellulose oligomers with different degrees of polymerization (DP), 7, 11, 18, 24, 26, 40 and 52, were prepared by hydrolysis of microcrystalline cellulose with phosphoric acid. These oligomers including the starting microcrystalline cellulose (DP 124) were converted to tris(3,5-dimethylphenylcarbamate) (CDMPC) derivatives by the reaction with an excess of 3,5-dimethylphenyl isocyanate to be used as the chiral stationary phase (CSP) in high-performance liquid chromatography (HPLC). The structures of the CDMPC derivatives were investigated by infrared spectroscopy (IR), 1H-NMR, circular dichroism (CD) and size exclusion chromatography (SEC), and the DPs of the derivatives estimated by SEC agreed with those estimated by 1H-NMR. After coating the derivatives on silica gel, their chiral recognition abilities were evaluated using eight racemates under a normal phase condition with a hexane-2-propanol (99/1) mixture as an eluent. The chiral recognition abilities of 7- and 11-mers, particularly the former, were lower than those of the higher oligomers from DP 18 to 52, which had rather similar abilities to that of 124-mer, although the abilities depended on the racemates. DP 18 seems to be sufficient for CDMPC to exhibit chiral recognition similar to that of the CDMPC with larger DPs. Date A point or period of time associated with an event in the lifecycle of the resource 2016 Subject The topic of the resource Chiral separation, enantiomer, phenylcarbamate, polysaccharide Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/molecules21111484 Source A related resource from which the described resource is derived Molecules Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Organic chemistry Language A language of the resource EN https://www.socictopen.socict.org/files/original/03bbf766311ca359939363981d82dc2f.pdf 79c5e91f09de8f91639107b442ae0333 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Exploring the Determinants of Perceived Risk of Middle East Respiratory Syndrome (MERS) in Korea Creator An entity primarily responsible for making the resource Sun Hee Kim, Seoyong Kim Description An account of the resource The world is turning into a risky society. Although modernization based on the developments in science and technology has increased individuals’ well-being and wealth, the perceived risk toward the complex technological system has increased. In a risky society, social accidents amplify the existing fear among individuals. It is generally assumed that each value, perception, and resource influences the fear of risk. However, very few studies have tested these three factors together within an integrated causal model. Therefore, the present study aimed to examine the determinants that influence the perceived risk in cases of Middle East Respiratory Syndrome (MERS), a deadly epidemic disease, in Korea. Based on the theoretical model, we analyzed the survey data collected from respondents (N = 814) in Korea. After controlling for variables such as sociodemographic characteristics, we examined how three competing factors, i.e., value, perception, and resource, influence the perceived risk of MERS. The analysis showed that trust and vulnerability variables in the perception factor, health state, and perceived knowledge in the resource factor had a significant impact on the perceived risk of MERS. Date A point or period of time associated with an event in the lifecycle of the resource 2018 Subject The topic of the resource Risk, Risk perception, risk communication, Value, resource, Middle East respiratory syndrome Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/ijerph15061168 Source A related resource from which the described resource is derived International Journal of Environmental Research and Public Health Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/b509282d7ada08242ba9121010c55f1c.pdf f4161fb94ab5939f68537f2daaa09ef3 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Soroprevalência de anticorpos anti-rotavírus do sorogrupo A em bovinos de uma fronteira pioneira na Amazônia brasileira Creator An entity primarily responsible for making the resource Paulo Eduardo Brandão, Adriana Cortez, Fernando Ferreira, José Soares Ferreira Neto, Fabio Gregori, Marcos Bryan Heinemann, Valéria Stacchini Ferreira Homem, Cesar Alejandro Rosales Rodriguez, José Antonio Jerez Description An account of the resource O rotavírus é um agente etiológico de diarréias de distribuição mundial, responsável por grandes prejuízos econômicos. Pesquisou-se a soroprevalência de anticorpos anti-rotavírus do sorogrupo A em bovinos criados no município de Uruará, utilizando a técnica da contraimunoeletroosmofore com a amostra NCDV como antígeno padrão. A prevalência de propriedades positivas foi de 95.6-100%. Diferenças significativas foram observadas entre as sucessivas faixas etárias, quando a soropositividade aumentou dos grupos mais jovens para os mais velhos, bem como entre fêmeas e machos maiores de 1 ano, quando a soropositividade foi maior no primeiro grupo. Date A point or period of time associated with an event in the lifecycle of the resource 2002 Subject The topic of the resource Estudos Soroepidemiológicos, anticorpos, rotavirus, bovinos, Amazônia Identifier An unambiguous reference to the resource within a given context DOI: 10.1590/S1413-95962002000100003 Source A related resource from which the described resource is derived Brazilian Journal of Veterinary Research and Animal Science Publisher An entity responsible for making the resource available Universidade de São Paulo Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Animal culture Language A language of the resource EN, PT