59 10 20655 https://www.socictopen.socict.org/files/original/9e3dbd5b6d3a0c0e6199d21ac76dbbd6.pdf 64561dd1203805c71ab8db2cca28c22d Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource A consensus approach to vertebrate de novo transcriptome assembly from RNA-seq data: Assembly of the duck (Anas platyrhynchos) transcriptome. Creator An entity primarily responsible for making the resource Joanna eMoreton, Stephen P Dunham, Richard D. Emes Description An account of the resource For vertebrate organisms where a reference genome is not available, de novo transcriptome assembly enables a cost effective insight into the identification of tissue specific or differentially expressed genes and variation of the coding part of the genome. However, since there are a number of different tools and parameters that can be used to reconstruct transcripts, it is difficult to determine an optimal method. Here we suggest a pipeline based on (1) assessing the performance of three different assembly tools (2) using both single and multiple k-mer approaches (3) examining the influence of the number of reads used in the assembly (4) merging assemblies from different tools. We use an example dataset from the vertebrate Anas platyrhynchos domestica (Pekin duck). We find that taking a subset of data enables a robust assembly to be produced by multiple methods without the need for very high memory capacity. The use of reads mapped back to transcripts (RMBT) and CEGMA (Core Eukaryotic Genes Mapping Approach) provides useful metrics to determine the completeness of assembly obtained. For this dataset the use of multiple k-mers in the assembly generated a more complete assembly as measured by greater number of RMBT and CEGMA score. Merged single k-mer assemblies are generally smaller but consist of longer transcripts, suggesting an assembly consisting of fewer fragmented transcripts. We suggest that the use of a subset of reads during assembly allows the relatively rapid investigation of assembly characteristics and can guide the user to the most appropriate transcriptome for particular downstream use. Transcriptomes generated by the compared assembly methods and the final merged assembly are freely available for download at http://dx.doi.org/10.6084/m9.figshare.1032613. Date A point or period of time associated with an event in the lifecycle of the resource 2014 Subject The topic of the resource RNA-Seq, assembly, high-throughput sequencing, Illumina, de novo transcriptome Identifier An unambiguous reference to the resource within a given context DOI: 10.3389/fgene.2014.00190 Source A related resource from which the described resource is derived Frontiers in Genetics Publisher An entity responsible for making the resource available Frontiers Media S.A. Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Genetics Language A language of the resource EN https://www.socictopen.socict.org/files/original/052fbdc0919bac35f5a1b259999cb19a.pdf 089ae48124acc1428401a60e24d03790 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Viral genome sequencing by random priming methods Creator An entity primarily responsible for making the resource Zhang Xinsheng, Afonso Claudio, Feldblyum Jeremy, Sengamalay Naomi, DePasse Jay, Kuzmickas Ryan, Halpin Rebecca, Djikeng Appolinaire, Anderson Norman G, Ghedin Elodie, Spiro David J Description An account of the resource Abstract Background Most emerging health threats are of zoonotic origin. For the overwhelming majority, their causative agents are RNA viruses which include but are not limited to HIV, Influenza, SARS, Ebola, Dengue, and Hantavirus. Of increasing importance therefore is a better understanding of global viral diversity to enable better surveillance and prediction of pandemic threats; this will require rapid and flexible methods for complete viral genome sequencing. Results We have adapted the SISPA methodology 123 to genome sequencing of RNA and DNA viruses. We have demonstrated the utility of the method on various types and sources of viruses, obtaining near complete genome sequence of viruses ranging in size from 3,000–15,000 kb with a median depth of coverage of 14.33. We used this technique to generate full viral genome sequence in the presence of host contaminants, using viral preparations from cell culture supernatant, allantoic fluid and fecal matter. Conclusion The method described is of great utility in generating whole genome assemblies for viruses with little or no available sequence information, viruses from greatly divergent families, previously uncharacterized viruses, or to more fully describe mixed viral infections. Date A point or period of time associated with an event in the lifecycle of the resource 2008 Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/1471-2164-9-5 Source A related resource from which the described resource is derived BMC Genomics Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Genetics, Biotechnology Language A language of the resource EN https://www.socictopen.socict.org/files/original/06177e37a41cfeb4bf5b4945cd34366a.pdf b95b59d5f340488bba8c19bbb60540a9 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Middle East respiratory syndrome in the Republic of Korea: transparency and communication are key Creator An entity primarily responsible for making the resource Isaac Chun-Hai Fung, Zion Tsz Ho Tse, Benedict Shing Bun Chan, King-Wa Fu Description An account of the resource None Date A point or period of time associated with an event in the lifecycle of the resource 2015 Subject The topic of the resource MERS-CoV, health communications, Outbreak Identifier An unambiguous reference to the resource within a given context DOI: 10.5365/wpsar.2015.6.2.011 Source A related resource from which the described resource is derived Western Pacific Surveillance and Response Publisher An entity responsible for making the resource available World Health Organization Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Public aspects of medicine, Medicine Language A language of the resource EN, ZH https://www.socictopen.socict.org/files/original/298742afe2dda85083550bbb7abfbd4f.pdf b102fa0313347b5e3c9231a7c023ab8f Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Encephalitis with reversible splenial and deep cerebral white matter lesions associated with Epstein–Barr virus infection in adults Creator An entity primarily responsible for making the resource Guo YJ, Wang SH, Jiang B, Li JL, Liu L, Wang J., Zhao WQ, Jia J Description An account of the resource Yanjun Guo,1 Shuhui Wang,1 Bin Jiang,1 Jianle Li,1 Lei Liu,2 Jiawei Wang,2 Weiqin Zhao,1 Jianping Jia1 1Department of Neurology, Beijing Friendship Hospital, Capital Medical University. Beijing, China; 2Department of Neurology, Beijing Tongren Hospital, Capital Medical University, Beijing, China Background: Approximately 200 cases of mild encephalitis with reversible splenial (MERS) and deep cerebral white matter lesions have been reported since MERS was first defined in 2004. MERS occurs more frequently in children; in adults, only ~60 cases have been reported. Until now, only four cases of MERS in adults have been associated with Epstein–Barr virus (EBV). Case presentation: We report three adult cases of MERS associated with EBV infection in China. For all three patients, cranial magnetic resonance imaging (MRI) indicated solitary reversible splenial and/or perilateral ventricle white matter lesions with reduced diffusion. In the present report, all patients were adults presenting with high fever, headache, apathy, and confusion, as well as significant signs of meningeal inflammation. These symptoms peaked 10–14 days after disease onset, with serious hyponatremia (112–129 mmol/L), an elevated cerebrospinal fluid white blood cell count (80–380/mm3), and significantly increased protein levels (1,010–1,650 mg/dL). Cranial MRI indicated abnormal signal intensity in the splenium of corpus callosum and symmetrically reversible lesions scattered in the thalamus and deep cerebral white matter. The clinical symptoms tended to improve after ~10–14 days of antiviral treatment. However, these patients recovered more slowly than patients with viral meningitis. Conclusion: MERS associated with EBV infection in adults occurs less frequently but with more severe symptoms than in children. EBV infection should be considered for patients with MERS symptoms. MERS has a good prognosis. Keywords: mild encephalitis with reversible splenial lesions, Epstein-Barr virus, apathy, hyponatremia, corpus fluid  Date A point or period of time associated with an event in the lifecycle of the resource 2017 Subject The topic of the resource Mild encephalitis with reversible splenial, Epstein-Barr virus, magnetic resonance imaging, Adults, Case Report Identifier An unambiguous reference to the resource within a given context DOI: Source A related resource from which the described resource is derived Neuropsychiatric Disease and Treatment Publisher An entity responsible for making the resource available Dove Medical Press Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Neurosciences. Biological psychiatry. Neuropsychiatry, Neurology. Diseases of the nervous system Language A language of the resource EN https://www.socictopen.socict.org/files/original/02c74448f898bfeffeb404c4ce026b66.pdf 73fe74e29d86d9d43795e2af37e7175c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Intubating Ebola Patients: Technical Limitations of Extensive Personal Protective Equipment Creator An entity primarily responsible for making the resource Warren Wiechmann, Shannon Toohey, Cassandra Majestic, Megan Boysen-Osborn Description An account of the resource As hospitals across the nation were preparing for thepossibility of Ebola or Middle Eastern respiratory syndrome(MERS-CoV) cases, healthcare workers underwent intricatetraining in the use of personal protective equipment (PPE).An Ebola or MERS-CoV patient requiring intubation placesa healthcare worker at risk for exposure to bodily secretions.The procedure must be performed only after appropriatePPE is donned.1 Intubating while wearing PPE is yet anotherchallenge identified in caring for these patients. Manualdexterity and free movement decreases when wearing PPE,and may increase length of time to successful intubation. Date A point or period of time associated with an event in the lifecycle of the resource 2015 Subject The topic of the resource Ebola, personal protective equipment, Emergency medicine Identifier An unambiguous reference to the resource within a given context DOI: 10.5811/westjem.2015.10.28779 Source A related resource from which the described resource is derived Western Journal of Emergency Medicine Publisher An entity responsible for making the resource available eScholarship Publishing, University of California Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine, Medical emergencies. Critical care. Intensive care. First aid Language A language of the resource EN https://www.socictopen.socict.org/files/original/3567a2e98ee31234bcf055883f282edc.pdf 4dfdbb3caaca86b0edc6ae86526cdf3d Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Preparedness for molecular testing of Middle East respiratory syndrome coronavirus among laboratories in the Western Pacific Region Creator An entity primarily responsible for making the resource Raynal C Squires, Frank Konings Date A point or period of time associated with an event in the lifecycle of the resource 2014 Subject The topic of the resource MERS-CoV, western pacific region, molecular testing, coronavirus, survey, Middle East respiratory syndrome, preparedness Identifier An unambiguous reference to the resource within a given context DOI: 10.5365/wpsar.2014.5.3.001 Source A related resource from which the described resource is derived Western Pacific Surveillance and Response Publisher An entity responsible for making the resource available World Health Organization Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Public aspects of medicine, Medicine Language A language of the resource EN, ZH https://www.socictopen.socict.org/files/original/611ea409029cbdc96a783bfffa9f7f72.pdf 7b5cd96d395a8785fcab653c5fbaab61 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Determinants of the Strength of Auditing and Reporting Standards: a Cross-Country Study Creator An entity primarily responsible for making the resource Pran Krishansing Boolaky, Chandrasekhar Krishnamurti, Ariful Hoque Description An account of the resource Our study addresses the research gap regarding the absence of an empirical cross-country study on thedeterminants of the strength of auditing and reporting standards (SARS). Using data on 133 countries atvarious stages of development, we examine the role of environmental factors that influence a country’sstrength of auditing and reporting standards. Our empirical results confirm that institutional infrastructure,financial market development and higher education and training jointly influence a country’s strength ofauditing and reporting standards. We obtain qualitatively similar subsample results when we partitioncountries on the basis of economic development. Date A point or period of time associated with an event in the lifecycle of the resource 2013 Subject The topic of the resource auditing, reporting standards, development, global Identifier An unambiguous reference to the resource within a given context DOI: http://dx.doi.org/10.14453/aabfj.v7i4.3 Source A related resource from which the described resource is derived Australasian Accounting, Business and Finance Journal Publisher An entity responsible for making the resource available University of Wollongong Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Business Language A language of the resource EN https://www.socictopen.socict.org/files/original/0c1f9bd6bac42c3844d338be197b4b0d.pdf 1ee63eb5b0762570a78caf97bed39a30 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Altering SARS Coronavirus Frameshift Efficiency Affects Genomic and Subgenomic RNA Production Creator An entity primarily responsible for making the resource Ewan P. Plant, Deborah R. Taylor, Jonathan D. Dinman, Ralph S. Baric, Amy C. Sims Description An account of the resource In previous studies, differences in the amount of genomic and subgenomic RNA produced by coronaviruses with mutations in the programmed ribosomal frameshift signal of ORF1a/b were observed. It was not clear if these differences were due to changes in genomic sequence, the protein sequence or the frequency of frameshifting. Here, viruses with synonymous codon changes are shown to produce different ratios of genomic and subgenomic RNA. These findings demonstrate that the protein sequence is not the primary cause of altered genomic and subgenomic RNA production. The synonymous codon changes affect both the structure of the frameshift signal and frameshifting efficiency. Small differences in frameshifting efficiency result in dramatic differences in genomic RNA production and TCID50 suggesting that the frameshifting frequency must stay above a certain threshold for optimal virus production. The data suggest that either the RNA sequence or the ratio of viral proteins resulting from different levels of frameshifting affects viral replication. Date A point or period of time associated with an event in the lifecycle of the resource 2013 Subject The topic of the resource SARS, severe acute respiratory syndrome, pseudoknot, ribosomal frameshifting, viral replication Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/v5010279 Source A related resource from which the described resource is derived Viruses Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology Language A language of the resource EN https://www.socictopen.socict.org/files/original/acc1c57694eb1b3d2640555122ef03d1.pdf 34c1409ac9a8fd83515da765c36e733b Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Amylmetacresol/2,4-dichlorobenzyl alcohol, hexylresorcinol, or carrageenan lozenges as active treatments for sore throat Creator An entity primarily responsible for making the resource Morokutti-Kurz M, Graf C, Prieschl-Grassauer E Description An account of the resource Martina Morokutti-Kurz, Christine Graf, Eva Prieschl-Grassauer Marinomed Biotechnologie GmbH, Vienna, Austria Abstract: Up to 80% of sore throats are caused by viruses. Several over the counter products are available which provide symptomatic, not causal relief. For such lozenges, containing the antiseptics and local anesthetics amylmetacresol (AMC) and 2,4-dichlorobenzyl alcohol (DCBA) or hexylresorcinol (HR), recently an additional virucidal effect was published. Therefore, we tested a set of Strepsils® lozenges, containing either HR (Max [#2]) or AMC/DCBA (Original [#3], Extra Strong [#4], Warm [#5], Orange and Vitamin C [#6], Sugar free Lemon [#7], Children/Strawberry [#8] and Soothing Honey and Lemon [#9]) for their antiviral efficiency against representatives of respiratory viruses known to cause sore throat: human rhinovirus (HRV) 1a, HRV8, influenza virus A H1N1n, Coxsackievirus A10, and human coronavirus (hCoV) OC43. The lozenges were tested head to head with Coldamaris® lozenges (#1), which contain the patented antiviral iota-carrageenan. None of the tested AMC/DCBA or HR containing lozenges shows any antiviral effectiveness against HRV8 at the tested concentrations, whereas all are moderately active against HRV1a. Only lozenge #5 shows any activity against hCoV OC43 and Coxsackievirus A10 at the tested concentrations. Similarly, only lozenge #3 is moderately active against influenza A H1N1n virus. The data indicates that neither the isolated effect of the active ingredients nor the pH but rather one or more of the excipients of the specific formulations are responsible for the antiviral effect of some of the AMC/DCBA or HR containing lozenges. In contrast, carrageenan-containing lozenges are highly active against all viruses tested. In another experiment, we showed that binding and inactivation of virus particles by iota-carrageenan are fast and highly effective. During the residence time of the lozenge in the mouth, the viral titer is reduced by 85% and 91% for influenza A virus and hCoV OC43, respectively. Carrageenan-containing lozenges are, therefore, suitable as causative therapy against viral infections of the throat. Keywords: local anesthetics, polymer, antiviral, respiratory viruses Date A point or period of time associated with an event in the lifecycle of the resource 2017 Subject The topic of the resource Local anesthetics, polymer, antiviral, Respiratory viruses Identifier An unambiguous reference to the resource within a given context DOI: Source A related resource from which the described resource is derived International Journal of General Medicine Publisher An entity responsible for making the resource available Dove Medical Press Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine (General) Language A language of the resource EN https://www.socictopen.socict.org/files/original/825db39671714e59a0c91fa8ea4e37b6.pdf ced9e1a2b7afafc3e6b1220fe304e89c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Monitoring the spread of swine enteric coronavirus diseases in the United States in the absence of a regulatory framework Creator An entity primarily responsible for making the resource Andres M Perez, Ana eAlba-Casals, Dane eGoede, Brian eMcCluskey, Robert eMorrison Description An account of the resource The reporting and monitoring of swine enteric coronavirus diseases (SECD), such as porcine epidemic diarrhea virus (PEDV) and porcine delta coronavirus (PDCoV), in the United States (US) has been challenging because of the absence of a regulatory framework and the emerging nature of these diseases. The National Animal Health Laboratory Network, the Emergency Management and the Response System and the Swine Health Monitoring Project were used to monitor the disease situation between May 2013 and March 2015. Important differences existed between and among them in terms of nature and extent of reporting. Here, we assessed the implementation of these systems from different perspectives, including a description and comparison of collected data, disease metrics, usefulness, simplicity, flexibility, acceptability, representativeness, timeliness and stability. This assessment demonstrates the limitations that the absence of premises identification imposes to certain databases, and the importance of federally-regulated frameworks in collecting accurate information on a timely-manner. This study also demonstrates the value that the voluntary and producer-organized systems may have in monitoring emerging diseases. The results from all three data sources help to establish the baseline information on SECD epidemiological dynamics after two years of disease spread in the country. Date A point or period of time associated with an event in the lifecycle of the resource 2016 Subject The topic of the resource Epidemiology, United States, monitoring, Surveillance, swine enteric coronavirus Identifier An unambiguous reference to the resource within a given context DOI: 10.3389/fvets.2016.00018 Source A related resource from which the described resource is derived Frontiers in Veterinary Science Publisher An entity responsible for making the resource available Frontiers Media S.A. Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Veterinary medicine Language A language of the resource EN