601 10 20655 https://www.socictopen.socict.org/files/original/ed051a1432cdec7d09a569d72e1100c2.pdf a471c1085dc8b310237f85138fb15c4b Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Interferon-β: treatment option against COVID-19 Creator An entity primarily responsible for making the resource Faiz Ul haq, Muhammad Usman Khan, Ayesha Muazzam, Hajrah Farooq, Javeria Iqbal, Muhammad Imran, Rabia Bashir, Sania Ahmad, Sara Arif Description An account of the resource In December 2019, an increasing number of cases of novel coronavirus (2019-nCoV) that were linked to seafood wholesale market have identified in Wuhan, China. Taxonomist declared 2019-nCoV as severe acute respiratory syndrome coronavirus- 2 (SARS-CoV-2) and the disease termed as COVID-19. Importantly, there is no approved drugs or vaccine against SARS-CoV-2. Current review is related to address treatment option for COVID-19. Interferon-β have shown significant activity against previous outbreak of SARS-CoV and MERS-CoV. Faced with an ongoing pandemic of SARS-CoV-2 and lack of effective treatment options, identifying compounds with antiviral activity has become a high priority. Efficacy of these treatments is still unclear. Therefore, final analysis is important to develop better treatment strategies for ongoing pandemic. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource coronavirus, covid-19, SARS-CoV-2, antiviral agents, interferon-β Identifier An unambiguous reference to the resource within a given context 10.4081/gc.2020.9093 Source A related resource from which the described resource is derived Geriatric Care Publisher An entity responsible for making the resource available PAGEPress Publications Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Geriatrics https://www.socictopen.socict.org/files/original/ae965cd000ab565eb03bb339113aac9f.pdf c64f9a673261139528f4251bf7d6a30e Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Resident education during Covid-19, virtual mock OSCE's via zoom: A pilot program. Creator An entity primarily responsible for making the resource Faiza A Khan, Matthew Williams, Charles A Napolitano Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource OSCE, resident education, Covid-19 education Identifier An unambiguous reference to the resource within a given context 10.1016/j.jclinane.2020.110107 Source A related resource from which the described resource is derived Journal of clinical anesthesia https://www.socictopen.socict.org/files/original/9bd3e8bd42372828b703f2e3735462da.pdf 1ace6e5b1b1fba5cc467ec89e3a8b78e Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Simulation in Neurosurgical Education During the COVID-19 Pandemic and Beyond. Creator An entity primarily responsible for making the resource Faizal A Haji Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource covid-19, simulation, postgraduate education, neurosurgery Identifier An unambiguous reference to the resource within a given context 10.1017/cjn.2020.234 Source A related resource from which the described resource is derived The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques https://www.socictopen.socict.org/files/original/39063f7cad2ee758a19ff0e8c0b83ec9.pdf 8f11c613a9978dd4c7ed5012d821a25b Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Anti-Inflammatory Properties of Drugs Used to Control COVID-19 and their Effects on the Renin-Angiotensin System and Angiotensin-Converting Enzyme-2 Creator An entity primarily responsible for making the resource Fakhreddin Jamali, Hamed Gilzad-Kohan Description An account of the resource COVID-19 infection is associated with systemic inflammation, and sometimes hyperinflammatory responses with cytokine storm. This plays a major role in COVID-19 severity and poor disease prognosis, even death. Higher levels of inflammatory hallmarks including C-reactive protein, ferritin, D-dimers, and cytokines such as interleukin (IL) -6, IL-10 and tumor necrosis factor- α (TNF-α) have been reported. Many anti-viral drugs have been tried, but none were proven fully effective. Supportive care and management of the complications that are caused mainly by inflammation might be the key to greater survival rates and shorter hospitalization (e.g., the use of remdesivir, lopinavir, ritonavir, umifenovir (arbidol), oseltamivir, ganciclovir, favipiravir, darunavir, hydroxychloroquine, chloroquine, colchicine, azithromycin, anakinra, canakinumab, tocilizumab, siltuximab, sarilumab, Type 1 interferon, interferon β-1a, interferon α-2b, baricitinib, ruxolitinib, fedratinib, methylprednisolone and dexamethasone). However, the efficacy of these treatments still needs well-planned clinical trials. In such trials, careful attention must be paid to the duration of the treatment, the onset of beneficial effects, and the severity of the disease, otherwise, the outcomes may still remain inconclusive. Herein, we present a review of the current drugs, which are being used in the management of the disease and their anti-inflammatory properties. We also investigated if these drugs directly interact with Angiotensin-Converting Enzyme (ACE 2), which is a crucial component of the virus entry to the cells. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.18433/jpps31346 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Therapeutics. Pharmacology, Pharmacy and materia medica https://www.socictopen.socict.org/files/original/0d07eca5258438a434c9ff8d0fa478db.pdf 862781505a112d297c23570994ebc11c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource La estructura que sostiene la vida: alimento e intercambio entre los kogi Creator An entity primarily responsible for making the resource Falk Parra Witte Description An account of the resource Este artículo se centra en los «pagamentos» (zubiji) y las «confesiones» (aluna ishguashi) de los kogi, como prácticas de conocimiento que ilustran la naturaleza ecológica del intercambio en la Sierra Nevada de Santa Marta, Colombia. Muestra cómo la reciprocidad es cuestión de alimento o nutrición y se enmarca en órdenes y asociaciones complejas semejantes a las composiciones andinas del cosmos, el territorio y la sociedad. En términos kogi, estos patrones no son simplemente formas de clasificación «analogistas», sino que constituyen una red o tejido de relaciones y flujos basados en la regulación del equilibrio ecológico como el mantenimiento de estructuras cosmológicas de soporte. Esta unidad equivale a un organismo vivo y pensante que genera y sostiene a todos los seres y cosas, a la vez que integra su forma y sustancia, su espíritu y su materia. De esta forma, el artículo arroja mayor luz sobre las dimensiones ontológicas de la región istmo-colombiana, y termina haciendo énfasis en su relevancia para entender los actuales problemas ambientales en torno a la Sierra Nevada. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Cosmología, alimento, ecología, intercambio, kogi Identifier An unambiguous reference to the resource within a given context 10.25058/20112742.n36.04 Source A related resource from which the described resource is derived Tabula Rasa: Revista de Humanidades Publisher An entity responsible for making the resource available Universidad Colegio Mayor de Cundinamarca Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Social sciences (General), Anthropology Relation A related resource <a href="http://www.redalyc.org/articulo.oa?id=39664893005" target="_blank" rel="noreferrer noopener">http://www.redalyc.org/articulo.oa?id=39664893005</a> https://www.socictopen.socict.org/files/original/93da25120251bd6ce28e7895d144b066.pdf b13fd3e8dbf49712041e25a48db00f4c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Analysis of the host transcriptome from demyelinating spinal cord of murine coronavirus-infected mice. Creator An entity primarily responsible for making the resource Fan LI, Ruth Elliott, Susan R. Weiss, Brian D. Gregory, Isabelle Dragomir, Ming Ming W Chua Description An account of the resource Persistent infection of the mouse central nervous system (CNS) with mouse hepatitis virus (MHV) induces a demyelinating disease pathologically similar to multiple sclerosis and is therefore used as a model system. There is little information regarding the host factors that correlate with and contribute to MHV-induced demyelination. Here, we detail the genes and pathways associated with MHV-induced demyelinating disease in the spinal cord. High-throughput sequencing of the host transcriptome revealed that demyelination is accompanied by numerous transcriptional changes indicative of immune infiltration as well as changes in the cytokine milieu and lipid metabolism. We found evidence that a Th1-biased cytokine/chemokine response and eicosanoid-derived inflammation accompany persistent MHV infection and that antigen presentation is ongoing. Interestingly, increased expression of genes involved in lipid transport, processing, and catabolism, including some with known roles in neurodegenerative diseases, coincided with demyelination. Lastly, expression of several genes involved in osteoclast or bone-resident macrophage function, most notably TREM2 and DAP12, was upregulated in persistently infected mouse spinal cord. This study highlights the complexity of the host antiviral response, which accompany MHV-induced demyelination, and further supports previous findings that MHV-induced demyelination is immune-mediated. Interestingly, these data suggest a parallel between bone reabsorption by osteoclasts and myelin debris clearance by microglia in the bone and the CNS, respectively. To our knowledge, this is the first report of using an RNA-seq approach to study the host CNS response to persistent viral infection. Date A point or period of time associated with an event in the lifecycle of the resource 2013 Identifier An unambiguous reference to the resource within a given context DOI: 10.1371/journal.pone.0075346 Source A related resource from which the described resource is derived PLoS ONE Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Science, Medicine https://www.socictopen.socict.org/files/original/55e16c48dbd8fea18500566acf6b9836.pdf 2ac9e7e18b54cdd977712d90f2e5b945 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Prevalence and phylogenetic analysis of porcine diarrhea associated viruses in southern China from 2012 to 2018 Creator An entity primarily responsible for making the resource Fanfan Zhang, Suxian Luo, Jun Gu, Zhi-Quan Li, Kai Li, Wei-feng YUAN, Yu Ye, Hao Li, Zhen Ding, Deping Song, Yu-Xin Tang Description An account of the resource Abstract Background In China, large-scale outbreaks of severe diarrhea caused by viruses have occurred in pigs since late 2010. To investigate the prevalence and genetic evolution of diarrhea-associated viruses responsible for the outbreaks, a total of 2987 field diarrheal samples collected from 168 pig farms in five provinces in Southern China during 2012–2018 were tested. Results Porcine epidemic diarrhea virus (PEDV) was most frequently detected virus with prevalence rates between 50.21 and 62.10% in samples, and 96.43% (162/168) in premises, respectively. Porcine deltacoronavirus (PDCoV) was the second prevalent virus with prevalence rates ranging from 19.62 to 29.19% in samples, and 70.24% (118/168) in premises, respectively. Both transmissible gastroenteritis virus (TGEV) and porcine rotavirus (PoRV) were detected at low prevalence rates of Date A point or period of time associated with an event in the lifecycle of the resource 2019 Subject The topic of the resource Porcine diarrhea, Prevalence, porcine epidemic diarrhea virus, porcine deltacoronavirus, Swine acute diarrhea syndrome coronavirus Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/s12917-019-2212-2 Source A related resource from which the described resource is derived BMC Veterinary Research Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Veterinary medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/e71d13955fc72878990540026a6e6c45.pdf 2ac9e7e18b54cdd977712d90f2e5b945 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Prevalence and phylogenetic analysis of porcine diarrhea associated viruses in southern China from 2012 to 2018 Creator An entity primarily responsible for making the resource Fanfan Zhang, Suxian Luo, Jun Gu, Zhiquan Li, Kai Li, Weifeng Yuan, Yu Ye, Hao Li, Zhen Ding, Deping Song, Yuxin Tang Description An account of the resource Abstract Background In China, large-scale outbreaks of severe diarrhea caused by viruses have occurred in pigs since late 2010. To investigate the prevalence and genetic evolution of diarrhea-associated viruses responsible for the outbreaks, a total of 2987 field diarrheal samples collected from 168 pig farms in five provinces in Southern China during 2012–2018 were tested. Results Porcine epidemic diarrhea virus (PEDV) was most frequently detected virus with prevalence rates between 50.21 and 62.10% in samples, and 96.43% (162/168) in premises, respectively. Porcine deltacoronavirus (PDCoV) was the second prevalent virus with prevalence rates ranging from 19.62 to 29.19% in samples, and 70.24% (118/168) in premises, respectively. Both transmissible gastroenteritis virus (TGEV) and porcine rotavirus (PoRV) were detected at low prevalence rates of Date A point or period of time associated with an event in the lifecycle of the resource 2019 Subject The topic of the resource Prevalence, Porcine epidemic diarrhea virus, porcine deltacoronavirus, Porcine diarrhea, Swine acute diarrhea syndrome coronavirus Identifier An unambiguous reference to the resource within a given context 10.1186/s12917-019-2212-2 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Veterinary medicine https://www.socictopen.socict.org/files/original/b531ec7cc0a5620958b1a3fbe6fbc763.pdf 8f079fa19710b964544df6e9825b9e43 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource A simple and rapid identification method for newly emerged porcine Deltacoronavirus with loop-mediated isothermal amplification Creator An entity primarily responsible for making the resource Fanfan Zhang, Yu Ye, Deping Song, Nan-Nan Guo, Qi Peng, Anqi Li, Xingrong Zhou, Yanjun Chen, Min Zhang, Dong-Yan Huang, Yu-Xin Tang Description An account of the resource Abstract Background Porcine Deltacoronavirus (PDCoV) is a newly emerged enteropathogenic coronavirus that causes diarrhea and mortality in neonatal piglets. PDCoV has spread to many countries around the world, leading to significant economic losses in the pork industry. Therefore, a rapid and sensitive method for detection of PDCoV in clinical samples is urgently needed. Results In this study, we developed a single-tube one-step reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay specific for nucleocapsid gene to diagnose and monitor PDCoV infections. The detection limit of RT-LAMP assay was 1 × 101 copies of PDCoV, which was approximately 100-fold more sensitive than gel-based one-step reverse transcription polymerase chain reaction (RT-PCR). This assay could specifically amplify PDCoV and had no cross amplification with porcine epidemic diarrhea virus (PEDV), transmissible gastroenteritis virus (TGEV), porcine kobuvirus (PKoV), porcine astrovirus (PAstV), porcine reproductive and respiratory syndrome virus (PRRSV), classic swine fever virus (CSFV), and porcine circovirus type 2 (PCV2). By screening a panel of clinical specimens (N = 192), this method presented a similar sensitivity with nested RT-PCR and was 1–2 log more sensitive than conventional RT-PCR in detection of PDCoV. Conclusions The RT-LAMP assay established in this study is a potentially valuable tool, especially in low-resource laboratories and filed settings, for a rapid diagnosis, surveillance, and molecular epidemiology investigation of PDCoV infections. To the best of our knowledge, this is the first work for detection of newly emerged PDCoV with LAMP technology. Date A point or period of time associated with an event in the lifecycle of the resource 2017 Subject The topic of the resource Porcine Deltacoronavirus (PDCoV), RT-LAMP, rapid diagnosis Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/s40659-017-0135-6 Source A related resource from which the described resource is derived Biological Research Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General) Language A language of the resource EN https://www.socictopen.socict.org/files/original/f78cad9d2b482b7d16f946c7d22a77a5.pdf 9e0630a459257394fab5309054bc2116 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource MERS Coronavirus: An Emerging Zoonotic Virus Creator An entity primarily responsible for making the resource Fang Li, Lanying Du Description An account of the resource Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging virus that was first reported in humans in June 2012 [...] Date A point or period of time associated with an event in the lifecycle of the resource 2019 Subject The topic of the resource n/a Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/v11070663 Source A related resource from which the described resource is derived Viruses Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology Language A language of the resource EN