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Molecular Epidemiology of SARS-associated Coronavirus, Beijing
Single nucleotide variations (SNVs) at 5 loci (17564, 21721, 22222, 23823, and 27827) were used to define the molecular epidemiologic characteristics of severe acute respiratory syndrome–associated coronavirus (SARS-CoV) from Beijing patients. Five…
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Pulmonary Tuberculosis and SARS, China
Position: 1860 (52 views)
Prevalence and Influencing Factors of Anxiety and Depression Symptoms in the First-Line Medical Staff Fighting Against COVID-19 in Gansu
BackgroundThe outbreak of novel coronavirus pneumonia (COVID-19) has brought enormous physical and psychological pressure on Chinese medical staff. It is extremely important to understand the prevalence and influencing factors of anxiety and…
Position: 20383 (12 views)
Using Geotagged Social Media Data to Explore Sentiment Changes in Tourist Flow: A Spatiotemporal Analytical Framework
Understanding sentiment changes in tourist flow is critical in designing exciting experiences for tourists and promoting sustainable tourism development. This paper proposes a novel analytical framework to investigate the tourist sentiment changes…
Position: 10316 (25 views)
Adaptive evolution of the spike gene of SARS coronavirus: changes in positively selected sites in different epidemic groups
Abstract Background It is believed that animal-to-human transmission of severe acute respiratory syndrome (SARS) coronavirus (CoV) is the cause of the SARS outbreak worldwide. The spike (S) protein is one of the best characterized proteins of…
Position: 14136 (21 views)
Crystal structure of Middle East respiratory syndrome coronavirus helicase.
Middle East respiratory syndrome coronavirus (MERS-CoV) remains a threat to public health worldwide; however, effective vaccine or drug against CoVs remains unavailable. CoV helicase is one of the three evolutionary most conserved proteins in…
Position: 8110 (28 views)
High Resolution CT Imaging Dynamic Follow-Up Study of Novel Coronavirus Pneumonia
Objective: To explore the clinical characteristics and dynamic follow-up changes of high resolution CT (HRCT) in 270 patients with Coronavirus Disease 2019 (COVID-19) pneumonia.Methods: Two hundred seventy COVID-19 pneumonia patients were…
Position: 12140 (23 views)
Reconcile the debate over protective effects of BCG vaccine against COVID-19
Abstract While awaiting the COVID-19 vaccines, researchers have been actively exploring the effectiveness of existing vaccines against the new virus, among which the BCG vaccine (Bacillus Calmette-Guérin) receives the most attention. While many…
Position: 10316 (25 views)
DV-Curve Representation of Protein Sequences and Its Application
Based on the detailed hydrophobic-hydrophilic(HP) model of amino acids, we propose dual-vector curve (DV-curve) representation of protein sequences, which uses two vectors to represent one alphabet of protein sequences. This graphical representation…
Position: 6923 (30 views)
Clinical and Epidemiological Characteristics of COVID-19 Patients in Chongqing China
Objectives: To study in-depth the clinical and epidemiological characteristics of pneumonia resulting from COVID-19 and provide evidence for effective public health decisions.Methods: This was a retrospective, single-center research study.…
Position: 15184 (20 views)