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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Functional characterization of endogenous siRNA target genes in &lt;it&gt;Caenorhabditis elegans&lt;/it&gt;</text>
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                <text>Heikkinen Liisa, Asikainen Suvi, Wong Garry, Storvik Markus</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>Abstract Background Small interfering RNA (siRNA) molecules mediate sequence specific silencing in RNA interference (RNAi), a gene regulatory phenomenon observed in almost all organisms. Large scale sequencing of small RNA libraries obtained from C. elegans has revealed that a broad spectrum of siRNAs is endogenously transcribed from genomic sequences. The biological role and molecular diversity of C. elegans endogenous siRNA (endo-siRNA) molecules, nonetheless, remain poorly understood. In order to gain insight into their biological function, we annotated two large libraries of endo-siRNA sequences, identified their cognate targets, and performed gene ontology analysis to identify enriched functional categories. Results Systematic trends in categorization of target genes according to the specific length of siRNA sequences were observed: 18- to 22-mer siRNAs were associated with genes required for embryonic development; 23-mers were associated uniquely with post-embryonic development; 24–26-mers were associated with phosphorus metabolism or protein modification. Moreover, we observe that some argonaute related genes associate with siRNAs with multiple reads. Sequence frequency graphs suggest that different lengths of siRNAs share similarities in overall sequence structure: the 5' end begins with G, while the body predominates with U and C. Conclusion These results suggest that the lengths of endogenous siRNA molecules are consequential to their biological functions since the gene ontology categories for their cognate mRNA targets vary depending upon their lengths.</text>
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              <elementText elementTextId="19380">
                <text>2008</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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                <text>DOI: 10.1186/1471-2164-9-270</text>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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                <text>BMC Genomics</text>
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            <description>An entity responsible for making the resource available</description>
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                <text>BMC</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Genetics, Biotechnology</text>
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            <description>A language of the resource</description>
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                <text>EN</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Agricultura sostenible</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Agricultura sostenible</text>
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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Functional Diversity in Ferns Is Driven by Species Richness Rather Than by Environmental Constraints</text>
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                <text>Dietmar Quandt, Daniela Aros-Mualin, Sarah Noben, Dirk N. Karger, César I. Carvajal-Hernández, Laura Salazar, Adriana Hernández-Rojas, Jürgen Kluge, Michael A. Sundue, Marcus Lehnert, Michael Kessler</text>
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            <description>An account of the resource</description>
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                <text>Functional traits determine how species interact with their abiotic and biotic environment. In turn, functional diversity describes how assemblages of species as a whole are adapted to their environment, which also determines how they might react to changing conditions. To fully understand functional diversity, it is fundamental to (a) disentangle the influences of environmental filtering and species richness from each other, (b) assess if the trait space saturates at high levels of species richness, and (c) understand how changes in species numbers affect the relative importance of the trait niche expansion and packing. In the present study, we determined functional diversity of fern assemblages by describing morphological traits related to resource acquisition along four tropical elevational transects with different environmental conditions and species richness. We used several functional diversity indices and their standardized effect size to consider different aspects of functional diversity. We contrasted these aspects of functional diversity with climate data and species richness using linear models and linear mixed models. Our results show that functional morphological trait diversity was primarily driven by species richness and only marginally by environmental conditions. Moreover, increasing species richness contributed progressively to packing of the morphological niche space, while at the same time decreasing morphological expansion until a saturation point was reached. Overall, our findings suggest that the density of co-occurring species is the fundamental driving force of morphological niche structure, and environmental conditions have only an indirect influence on fern resource acquisition strategies.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2021</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>Ferns, Functional diversity, community assembly, elevational gradient, environmental filtering, species richness</text>
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            <description>An unambiguous reference to the resource within a given context</description>
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                <text>10.3389/fpls.2020.615723</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="221406">
                <text>Frontiers in Plant Science</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="221407">
                <text>Frontiers Media S.A.</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Plant culture</text>
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            <description>A related resource</description>
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                <text>&lt;a href="https://www.frontiersin.org/articles/10.3389/fpls.2020.615723/full" target="_blank" rel="noreferrer noopener"&gt;https://www.frontiersin.org/articles/10.3389/fpls.2020.615723/full&lt;/a&gt;</text>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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            <description>A name given to the resource</description>
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                <text>Functional genomics highlights differential induction of antiviral pathways in the lungs of SARS-CoV-infected macaques.</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="21966">
                <text>Anna de Lang, Tracey Baas, Thomas Teal, Lonneke M Leijten, Brandon Rain, Albert D Osterhaus, Bart L. Haagmans, Michael G. Katze</text>
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            <description>An account of the resource</description>
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                <text>The pathogenesis of severe acute respiratory syndrome coronavirus (SARS-CoV) is likely mediated by disproportional immune responses and the ability of the virus to circumvent innate immunity. Using functional genomics, we analyzed early host responses to SARS-CoV infection in the lungs of adolescent cynomolgus macaques (Macaca fascicularis) that show lung pathology similar to that observed in human adults with SARS. Analysis of gene signatures revealed induction of a strong innate immune response characterized by the stimulation of various cytokine and chemokine genes, including interleukin (IL)-6, IL-8, and IP-10, which corresponds to the host response seen in acute respiratory distress syndrome. As opposed to many in vitro experiments, SARS-CoV induced a wide range of type I interferons (IFNs) and nuclear translocation of phosphorylated signal transducer and activator of transcription 1 in the lungs of macaques. Using immunohistochemistry, we revealed that these antiviral signaling pathways were differentially regulated in distinctive subsets of cells. Our studies emphasize that the induction of early IFN signaling may be critical to confer protection against SARS-CoV infection and highlight the strength of combining functional genomics with immunohistochemistry to further unravel the pathogenesis of SARS.</text>
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            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2007</text>
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              <elementText elementTextId="21969">
                <text>DOI: 10.1371/journal.ppat.0030112</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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                <text>PLoS Pathogens</text>
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            <description>An entity responsible for making the resource available</description>
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                <text>Public Library of Science (PLoS)</text>
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                <text>Biology (General), Immunologic diseases. Allergy</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Functional Role of Dietary Intervention to Improve the Outcome of COVID-19: A Hypothesis of Work</text>
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                <text>Antonietta Messina, Vincenzo Monda, Giovanni Messina, Marco Carotenuto, Anna Valenzano, Marcellino Monda, Giuseppe Cibelli, Francesco Sessa, Luigi Cipolloni, Paolo Murabito, Giulio Di Mizio, Daniela Pisanelli, Rita Polito, Alessia Scarinci, Nunzio Di Nunno</text>
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                <text>Background: On the 31 December 2019, the World Health Organization (WHO) was informed of a cluster of cases of pneumonia of unknown origin detected in Wuhan City, Hubei Province, China. The infection spread first in China and then in the rest of the world, and on the 11th of March, the WHO declared that COVID-19 was a pandemic. Taking into consideration the mortality rate of COVID-19, about 5–7%, and the percentage of positive patients admitted to intensive care units being 9–11%, it should be mandatory to consider and take all necessary measures to contain the COVID-19 infection. Moreover, given the recent evidence in different hospitals suggesting IL-6 and TNF-α inhibitor drugs as a possible therapy for COVID-19, we aimed to highlight that a dietary intervention could be useful to prevent the infection and/or to ameliorate the outcomes during therapy. Considering that the COVID-19 infection can generate a mild or highly acute respiratory syndrome with a consequent release of pro-inflammatory cytokines, including IL-6 and TNF-α, a dietary regimen modification in order to improve the levels of adiponectin could be very useful both to prevent the infection and to take care of patients, improving their outcomes.</text>
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                <text>2020</text>
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                <text>IL-6, adiponectin, lung infections, ω-3 PUFAs, COVID-19, diet therapies</text>
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                <text>DOI: 10.3390/ijms21093104</text>
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                <text>International Journal of Molecular Sciences</text>
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                <text>MDPI AG</text>
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                <text>Biology (General), Chemistry</text>
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                <text>Functional studies of the coronavirus nonstructural proteins</text>
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            <name>Creator</name>
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              <elementText elementTextId="62900">
                <text>Yanglin Qiu, Kai  Xu</text>
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                <text>Coronaviruses, including SARS-CoV, SARS-CoV-2, and MERS-CoV, have caused contagious and fatal respiratory diseases in humans worldwide. Notably, the coronavirus disease 19 (COVID-19) caused by SARS-CoV-2 spread rapidly in early 2020 and became a global pandemic. The nonstructural proteins of coronaviruses are critical components of the viral replication machinery. They function in viral RNA transcription and replication, as well as counteracting the host innate immunity. Studies of these proteins not only revealed their essential role during viral infection but also help the design of novel drugs targeting the viral replication and immune evasion machinery. In this review, we summarize the functional studies of each nonstructural proteins and compare the similarities and differences between nonstructural proteins from different coronaviruses.</text>
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                <text>2020</text>
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                <text>coronavirus, covid-19, SARS-CoV-2, drug discovery, non-structural proteins</text>
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              <elementText elementTextId="62904">
                <text>10.37175/stemedicine.v1i2.39</text>
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                <text>Epidemiology and Health</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Biology (General), Medicine (General)</text>
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                  <text>Agricultura sostenible</text>
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                  <text>Dominio científico: Agricultura sostenible</text>
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                <text>Functional Traits of Olive Varieties and Their Relationship with the Tolerance Level towards Verticillium Wilt</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="211164">
                <text>Martina Cardoni, Jesús Mercado-Blanco, Rafael Villar</text>
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            <description>An account of the resource</description>
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                <text>Verticillium wilt of olive (VWO), caused by the soil-borne pathogen Verticillium dahliae, is considered one of the most important diseases affecting this tree crop. One of the best VWO management measures is the use of tolerant cultivars. Remarkably, no information is available about olive functional traits and their potential relationship with tolerance to V. dahliae. Twenty-five selected functional traits (for leaf, stem, root and whole plant) were evaluated in six olive varieties differing in their VWO tolerance level to identify possible links between this phenotype and functional traits’ variation. High intervarietal diversity was found among cultivars and several functional traits were related with VWO tolerance. Tolerant varieties showed higher leaf area, dry matter content (leaf, stem and plant) and mass fraction for stems, but lower for leaves. Significant differences were also detected for root functional traits, tolerant cultivars displaying larger fine root diameter and lignin content but smaller specific length and area of thick and fine roots. Correlations were found among functional traits both within varieties and between levels of tolerance/susceptibility to VWO. Associations were observed between biomass allocation, dry matter content and VWO tolerance. The most relevant difference between tolerant and susceptible cultivars was related to root system architecture.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2021</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>Lignin, biomass allocation, breeding for resistance, dry matter content, leaf area, root architecture</text>
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            <name>Identifier</name>
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                <text>10.3390/plants10061079</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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                <text>Plants</text>
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            </elementTextContainer>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>MDPI AG</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Botany</text>
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            <description>A related resource</description>
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                <text>&lt;a href="https://www.mdpi.com/2223-7747/10/6/1079" target="_blank" rel="noreferrer noopener"&gt;https://www.mdpi.com/2223-7747/10/6/1079&lt;/a&gt;</text>
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                  <text>Agricultura sostenible</text>
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                  <text>Dominio científico: Agricultura sostenible</text>
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      <name>Text</name>
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            <description>A name given to the resource</description>
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                <text>Fundamentación de fuentes energéticas de baja potencia en casas de cultivos protegidos en Cuba</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="219072">
                <text>Luisa Villarino Fernández, Arcadio Ríos Hernández</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>Los cultivos protegidos consisten en la utilización de las llamadas “casas de tapado” que permiten la producción de hortalizas todo el año, espe- cialmente en los meses más cálidos y de sol intenso. Esta forma de producción es importante por asegurar el suministro de hortalizas frescas de alta calidad al mercado de frontera, turismo y población. Hoy día el cultivo protegido en el mundo se reconoce como una tecnología agrícola de avanzada. Por ser el sistema de producción de cultivos protegidos relativamente nuevo y de características diferentes a la producción abierta, no existen definidos aperos, máquinas, ni tecnologías para enfrentar la ejecución de estas labores, pues la mecanización en Cuba está basada en el empleo de tractores de potencia media y alta, los que por sus características no pueden trabajar en estas instalaciones. El presente trabajo tiene por objetivo determinar el cumplimiento de las exigencias técnicas y agrotécnicas, y los indicadores tecnológico-explotativos y económicos y de los tractores de baja potencia, realizando operaciones de subsolado, roturación, cruce, mullición y acanterado, Para este trabajo se seleccionó como área experimental una casa de cultivos protegidos modelo BK-2, que está generalizada en Cuba y como fuentes energéticas representativas se emplearon los tractores Carraro y MTZ-321. Esta casa protegida fue diseñada con el propósito de obtener rendimientos alrededor de 60 t/ha de hortalizas, y está basada en túneles 540 m2 ubicados en módulos que ocupan 1 ha, con el propósito de un mejor aprovechamiento del sistema de riego, la maquinaria y la energía eléctrica. Se confeccionó una metodología para realizar los experimentos basada en los Instructivos Técnicos para las investigaciones de los equipos utilizados. Los tractores con que se trabajaron eran no articulados y para ellos se calculó la franja de viraje necesaria en las casas de cultivos la cual fue de 3,84 m a 4,96 m. Como resultados se determinó que las productividades alcanzadas por los tractores MTZ-321 y Carraro son similares con cada uno de los aperos estudiados. No hay diferencias importantes entre los gastos totales de trabajo anuales, pero en cuanto a los gastos trasferidos, el MTZ-321 supera al Carraro en un 33% a 50%, lo cual se debe fundamentalmente al mayor consumo de combustible y es de destacar que todos cumplieron satisfactoriamente con las exigencias agrotécnicas.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2013</text>
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            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="219075">
                <text>Revista Ciencias Técnicas Agropecuarias</text>
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            <description>An entity responsible for making the resource available</description>
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                <text>Universidad Agraria de La Habana</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Agriculture, Environmental technology. Sanitary engineering</text>
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            <name>Relation</name>
            <description>A related resource</description>
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                <text>&lt;a href="http://www.redalyc.org/articulo.oa?id=93231387004" target="_blank" rel="noreferrer noopener"&gt;http://www.redalyc.org/articulo.oa?id=93231387004&lt;/a&gt;</text>
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                  <text>Agricultura sostenible</text>
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                  <text>Dominio científico: Agricultura sostenible</text>
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                <text>Fundamentación teológica para una ecología cristiana</text>
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                <text>David Miguel Trujillo</text>
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            <description>An account of the resource</description>
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                <text>La humanidad se encuentra sumergida en un problema que definitivamente debe afrontar: las actitudes antiecológicas que han traído graves consecuencias al planeta. Como son muchos los francos desde los cuales se puede hacer frente a estas actitudes, acá se hace un llamado desde la fe cristiana, específicamente la católica, para pensar en propuestas que transformen la visión de cada ciudadano y especialmente la de los cristianos. Como es posible que el paradigma antiecológico que sigue la humanidad de hoy haya sido influenciado por la religión, también es posible que en ella misma se encuentre la fundamentación teológica que permita la emergencia y puesta en práctica de una ecología cristiana. La revisión exhaustiva de las Sagradas Escrituras, la visión de algunos padres de la Iglesia y, la consideración del magisterio eclesial de los tres últimos pontífices, permitirán develar la comprensión de un conocimiento sobre la Creación, que se encuentra inmerso en el mundo teológico, para ofrecer algunos aportes a la educación. Esta siguió una metodología de tipo documental con un marcado carácter hermenéutico que permitió “religar” a la naturaleza y al hombre de forma armoniosa y amorosa, tal y como Dios proyectó su amor misericordioso desde el momento de la creación.</text>
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                <text>2020</text>
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                <text>Católico, Educación Ambiental, Religion, Sagradas Escrituras, naturaleza</text>
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                <text>10.33881/0123-8264.hop.22103</text>
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            <description>A related resource from which the described resource is derived</description>
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                <text>Horizontes Pedagógicos</text>
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            <description>An entity responsible for making the resource available</description>
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                <text>IberAm</text>
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                <text>Education (General), Theory and practice of education</text>
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            <description>A related resource</description>
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                <text>&lt;a href="https://horizontespedagogicos.ibero.edu.co/article/view/1817" target="_blank" rel="noreferrer noopener"&gt;https://horizontespedagogicos.ibero.edu.co/article/view/1817&lt;/a&gt;</text>
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                <text>Fundamentalismos, interculturalidad y procesos educativos. Construir puentes en lugar de muros</text>
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                <text>Susana Beatriz Sacavino</text>
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                <text>El presente trabajo parte de la realidad de los distintos fundamentalismos que vienen ganando fuerza en nuestras sociedades y sus consecuencias que favorecen actitudes y comportamientos de rechazo hacia los que consideran diferentes, amenazan los derechos humanos y la construcción de relaciones de acogida y respeto entre los distintos grupos sociales. El estudio tiene por finalidad profundizar en el concepto de fundamentalismo e identificar sus diversas modalidades. También propone cómo situarse en relación con esta problemática en la perspectiva de promover una sociedad plural y una educación ciudadana democrática e intercultural.  Integra el proyecto de investigación sobre Interculturalidad, Ecología de Saberes y Prácticas Educativas, desarrollado por el Grupo de Estudios Cotidiano, Educación y Cultura(s) del Departamento de Educación de la Pontificia Universidad Católica de Rio de Janeiro (PUC-Rio), con el apoyo económico del Consejo Nacional de Desarrollo Científico y Tecnológico (CNPq).Este trabajo está estructurado en dos partes. En un primer momento hace una aproximación a lo que se entiende por fundamentalismo, su surgimiento y la gama plural de fundamentalismos existentes en la contemporaneidad. A partir de ese contexto, en un segundo momento, presenta algunas estrategias educativas para construir puentes de diálogo y acogida mutua entre personas y grupos socioculturales y étnicos distintos, en lugar de levantar muros de odio, rechazo y discriminación. En la conclusión se tejen algunas consideraciones para la deconstrucción de los fundamentalismos, en la perspectiva de afirmación de los derechos humanos y la ciudadanía intercultural</text>
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                <text>2020</text>
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                <text>Derechos Humanos, Intolerancia, educación, fundamentalismo, interculturalidad</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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                <text>10.17533/udea.unipluri.20.2.03</text>
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            <name>Source</name>
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                <text>Uni-pluriversidad</text>
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                <text>Universidad de Antioquia</text>
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                <text>Special aspects of education, Education (General)</text>
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                <text>&lt;a href="https://revistas.udea.edu.co/index.php/unip/article/view/341263" target="_blank" rel="noreferrer noopener"&gt;https://revistas.udea.edu.co/index.php/unip/article/view/341263&lt;/a&gt;</text>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Agricultura sostenible</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Agricultura sostenible</text>
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                <text>Fundamentos de ecología integral</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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                <text>Rafael Amo Usanos</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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                <text>Este artículo pretende explorar la arquitectura interna de Laudato si’ en busca de las raíces de los principios fundamentales de la ecología integral. En este trabajo, una vez estudiados y considerados los principios «todo está conectado» y el «todo es superior a la parte» como los fundamentos de la encíclica, se aborda la teología de la creación de corte trinitario y la filosofía de la biología de los sistemas abiertos que se consideran los lugares donde echan las raíces los principios citados. Ahora bien, esta investigación también saca a la luz el ángulo muerto de la ecología integral: el puesto del hombre en el cosmos y su derivada ética. Por último, se propone la distinción entre vida y sujeto de la vida como ayuda para superar el reduccionismo que se puede filtrar desde el paradigma sistémico a la ecología integral.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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              <elementText elementTextId="179583">
                <text>2019</text>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="179584">
                <text>Laudato si’, antropocentrismo desviado, ecologia integral, termodinámica de la vida</text>
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            </elementTextContainer>
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          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="179585">
                <text>10.14422/ee.v94.i368.y2019.001</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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                <text>Estudios Eclesiásticos</text>
              </elementText>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="179587">
                <text>Universidad Pontificia Comillas</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Doctrinal Theology, Christianity</text>
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          <element elementId="46">
            <name>Relation</name>
            <description>A related resource</description>
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                <text>&lt;a href="https://revistas.comillas.edu/index.php/estudioseclesiasticos/article/view/8722" target="_blank" rel="noreferrer noopener"&gt;https://revistas.comillas.edu/index.php/estudioseclesiasticos/article/view/8722&lt;/a&gt;</text>
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