Navegar por los elementos (20655 total)
Ordenar por:
Genome and epigenome editing identify CCR9 and SLC6A20 as target genes at the 3p21.31 locus associated with severe COVID-19
Position: 17848 (17 views)
Genome evolution of SARS-CoV-2 and its virological characteristics
Abstract Coronavirus disease of 2019 (COVID-19), which originated in China in 2019, shows mild cold and pneumonia symptoms that can occasionally worsen and result in deaths. SARS-CoV-2 was reported to be the causative agent of the disease and was…
Position: 20538 (11 views)
Genome size and chromosome number of Psidium friedrichsthalianum (O. Berg) Nied (“Cas”) in six populations of Costa Rica
Psidium friedrichsthalianum Ndz es una especie nativa de América Central distribuida desde el sur de México hasta el norte de Colombia. Es un componente frutal común de la dieta costarricense, y es valorado industrialmente por su alto contenido de…
Position: 3655 (40 views)
Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross.
New systems genetics approaches are needed to rapidly identify host genes and genetic networks that regulate complex disease outcomes. Using genetically diverse animals from incipient lines of the Collaborative Cross mouse panel, we demonstrate a…
Position: 17848 (17 views)
Genome-wide analysis of codon usage bias in Bovine Coronavirus
Abstract Background Bovine coronavirus (BCoV) belong to the genus Betacoronavirus of the family Coronaviridae. BCoV are widespread around the world and cause enteric or respiratory infections among cattle, leading to important economic losses to the…
Position: 12095 (23 views)
Genome-wide analysis of DNA methylation, copy number variation, and gene expression in monozygotic twins discordant for primary biliary cirrhosis
Primary biliary cirrhosis (PBC) is an uncommon autoimmune disease with a homogeneous clinical phenotype that reflects incomplete disease concordance in monozygotic (MZ) twins. We have taken advantage of a unique collection consisting of genomic DNA…
Position: 11168 (24 views)
Genome-wide analysis of protein-protein interactions and involvement of viral proteins in SARS-CoV replication.
Analyses of viral protein-protein interactions are an important step to understand viral protein functions and their underlying molecular mechanisms. In this study, we adopted a mammalian two-hybrid system to screen the genome-wide intraviral…
Position: 5535 (33 views)
Genome-Wide Association Analysis for Stem Cross Section Properties, Height and Heading Date in a Collection of Spanish Durum Wheat Landraces
Durum wheat landraces have a high potential for breeding but they remain underexploited due to several factors, including the insufficient evaluation of these plant materials and the lack of efficient selection tools for transferring target traits…
Position: 6344 (31 views)
Genome-wide association studies of Shigella spp. and Enteroinvasive Escherichia coli isolates demonstrate an absence of genetic markers for prediction of disease severity
Abstract Background We investigated the association of symptoms and disease severity of shigellosis patients with genetic determinants of infecting Shigella and entero-invasive Escherichia coli (EIEC), because determinants that predict disease…
Position: 4325 (37 views)
Genomic Analysis and Lineage Identification of SARS-CoV-2 Strains in Migrants Accessing Europe Through the Libyan Route
Many African countries, representing the origin of the majority of refugees, asylum-seekers, and other migrants, toward regions bordering on the Mediterranean area, are experiencing sustained local transmission of severe acute respiratory syndrome…
Position: 5535 (33 views)