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Familial hypercholesterolemia and statins in the COVID-19 era: Mitigating the risk of ischemic stroke.
There is a continuing need for research about the underlying mechanisms behind ischemic strokes in COVID-19 patients. Pre-existing endothelial dysfunction, especially if it is accompanied by a viral infection of the endothelial cells may present an…
Position: 16107 (19 views)
Health and Well-Being of Athletes During the Coronavirus Pandemic: A Scoping Review
Background: The ongoing global pandemic has become the world's leading health problem, causing massive public fear and concern. Reports suggest that athletes are seeking mental health support, showing the pressures of boredom, and tension associated…
Position: 17851 (17 views)
Commentary: COVID-19 Mortality: A Matter of Vulnerability Among Nations Facing Limited Margins of Adaptation
Position: 19231 (15 views)
Increased Oxidative Stress in the Prefrontal Cortex as a Shared Feature of Depressive- and PTSD-Like Syndromes: Effects of a Standardized Herbal Antioxidant
Major depression (MD) and posttraumatic stress disorder (PTSD) share common brain mechanisms and treatment strategies. Nowadays, the dramatically developing COVID-19 situation unavoidably results in stress, psychological trauma, and high incidence of…
Position: 13088 (22 views)
5-Hydroxytryptamine, Glutamate, and ATP: Much More Than Neurotransmitters.
5-hydroxytryptamine (5-HT) is derived from the essential amino acid L-tryptophan. Although the compound has been studied extensively for its neuronal handling and synaptic actions, serotonin 5-HT receptors can be found extra-synaptically and not only…
Position: 15169 (20 views)
Management of SARS-CoV-2 Infection: Key Focus in Macrolides Efficacy for COVID-19
Macrolides (e.g., erythromycin, fidaxomicin, clarithromycin, and azithromycin) are a class of bacteriostatic antibiotics commonly employed in medicine against various gram-positive and atypical bacterial species mostly related to respiratory tract…
Position: 16107 (19 views)
Severe Acute Respiratory Syndrome Coronavirus 2-Induced Immune Activation and Death of Monocyte-Derived Human Macrophages and Dendritic Cells.
Studies of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected patients and experimentally infected animals indicate a critical role for augmented expression of proinflammatory chemokines and cytokines in severe disease. Here, we…
Position: 14105 (21 views)
Fluid and Electrolyte Disturbances in COVID-19 and Their Complications
The novel coronavirus disease 2019 (COVID-19) is the cause of an acute respiratory illness which has spread around the world. The virus infects the host by binding to the angiotensin-converting enzyme 2 (ACE2) receptors. Due to the presence of ACE2…
Position: 9482 (26 views)
Pulmonary Embolism and Acute Psychosis, a Case Report of an Outpatient with a Mild Course of COVID-19.
The increased risk for thromboembolism in hospitalized COVID-19 patients has been communicated extensively. The fact that home quarantined patients can develop pulmonary embolism, however, has so far not been reported. Furthermore, attention should…
Position: 17012 (18 views)
Comparison of All-Cause Mortality Between Individuals With COVID-19 and Propensity Score-Matched Individuals Without COVID-19 in South Korea.
We compared all-cause mortality between individuals in South Korea with and without coronavirus disease 2019 (COVID-19) using propensity score (PS) matching. This population-based cohort study used data from the National Health Insurance Service…
Position: 11189 (24 views)