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                  <text>Dominio científico: Coronavirus</text>
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                <text>Tempos de re-invenção, re-criação e re-encontros</text>
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                <text>Sirlei Antoninha Kroth Gaspareto, Zenaide Collet</text>
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                <text>Este texto busca fazer reflexões sobre o momento atual caracterizado pela pandemia da Covid-19. Evidenciamos, como ponto de partida, memórias de uma experiência fundamentada na Teologia da Libertação, a qual influenciou o surgimento dos Movimentos Sociais Populares, principalmente na região oeste de Santa Catarina. Realiza-se a análise de repetidas crises originadas no seio do sistema capitalista que, em sua perversidade, re-cria-se de múltiplas maneiras e se faz permanente na travessia de nossas vidas. E, em meio à pandemia, destaca-se a sofisticação tecnológica, os “paradigmas tecnocráticos” que, no dizer do Papa Francisco, orientam muitos governos ao redor do mundo, mas “não são suficientes para abordar esta crise, nem os outros grandes problemas da humanidade”. O texto menciona o importante papel das mulheres no enfrentamento à pandemia. Acrescenta-se à reflexão elementos do referencial bíblico cristão que fundamentam e provocam o questionamento: a que re-invenção, re-criação, re-encontros nos referimos? O propósito é refletir sobre a necessidade permanente de aprimorar os elementos narrativos e críticos considerados fundamentais enquanto perspectiva humana de continuidade da vida.</text>
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                <text>pandemia, crise, Escolhas, Reinvenção</text>
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                <text>10.14393/REP-2020-55650</text>
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                <text>Revista de Educação Popular</text>
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                <text>Editora da Universidade Federal de Uberlândia</text>
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                <text>Social Sciences, Labor in politics. Political activity of the working class</text>
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                <text>A University Students&amp;rsquo; Response to an Article on the Psychological Impacts of COVID-19 Pandemic Among University Students in Bench-Sheko Zone [Letter]</text>
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                <text>Malik SI, Ahmed M, Khattab N</text>
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                <text>Saba-Ikhlas Malik, Muna Ahmed, Nour Khattab Faculty of Medicine, St George&amp;rsquo;s University of London, London, UKCorrespondence: Saba-Ikhlas MalikFaculty of Medicine, St George&amp;rsquo;s University of London, London, UKEmail m1400090@sgul.ac.uk As university students, we read with great interest the article by Aylie et al about&amp;nbsp;the effect of the COVID-19 pandemic on university student mental health. The&amp;nbsp;article highlighted that there has been an increase in&amp;nbsp; depression, anxiety and stress&amp;nbsp;levels and the need for governmental organisations to integrate psychological&amp;nbsp;support into upcoming initiatives.1 &amp;nbsp; View the original paper by&amp;nbsp;Aylie and colleagues</text>
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                <text>Depression anxiety stress</text>
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                <text>Biotemas</text>
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                <text>Universidade Federal de Santa Catarina</text>
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                <text>Psychology, Industrial psychology</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Changes in Diet, Sleep, and Physical Activity Are Associated With Differences in Negative Mood During COVID-19 Lockdown</text>
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              <elementText elementTextId="81115">
                <text>Joanne Ingram, Greg Maciejewski, Christopher J. Hand</text>
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                <text>The United Kingdom and Scottish governments instigated a societal lockdown in response to the COVID-19 pandemic. Subsequently, many experienced substantial lifestyle changes alongside the stresses of potentially catching the virus or experiencing bereavement. Stressful situations and poorer health behaviors (e.g., higher alcohol consumption, unhealthy diet, poorer sleep quality, physical inactivity) are frequently linked to poor mental health. Our objective was to examine changes in health behaviors and their relationship with negative mood during COVID-19 lockdown. We also considered associations between health behaviors and socio-demographic differences and COVID-19-induced changes. 399 participants completed a questionnaire asking about their personal situation and health behaviors during lockdown as well as a negative mood scale. The significance threshold for all analyses was α = 0.05. Poorer diet was linked to more-negative mood, and to changes to working status. Poorer sleep quality was linked with more-negative mood, and with ‘shielding’ from the virus. Being less physically active was related to more-negative mood and student status, whereas being more physically active was linked to having or suspecting COVID-19 infection within the household. Increased alcohol consumption was linked to living with children, but not to negative mood. Changes to diet, sleep quality, and physical activity related to differences in negative mood during COVID-19 lockdown. This study adds to reports on poor mental health during lockdown and identifies lifestyle restrictions and changes to health behaviors which may, to some extent, be responsible for higher negative mood. Our data suggests that it is advisable to maintain or improve health behaviors during pandemic-associated restrictions.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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              <elementText elementTextId="81117">
                <text>2020</text>
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            <description>The topic of the resource</description>
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                <text>covid-19, lockdown, physical activity, Sleep, diet, alcohol</text>
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              <elementText elementTextId="81119">
                <text>10.3389/fpsyg.2020.588604</text>
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                <text>Epidemiology and Health</text>
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            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="81121">
                <text>Korean Society of Epidemiology</text>
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                <text>Psychology</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Propagation, Inactivation, and Safety Testing of SARS-CoV-2</text>
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                <text>Alexander S. Jureka, Jesus A. Silvas, Christopher F. Basler</text>
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                <text>In late 2019, a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, the capital of the Chinese province Hubei. Since then, SARS-CoV-2 has been responsible for a worldwide pandemic resulting in over 4 million infections and over 250,000 deaths. The pandemic has instigated widespread research related to SARS-CoV-2 and the disease that it causes, COVID-19. Research into this new virus will be facilitated by the availability of clearly described and effective procedures that enable the propagation and quantification of infectious virus. As work with the virus is recommended to be performed at biosafety level 3, validated methods to effectively inactivate the virus to enable the safe study of RNA, DNA, and protein from infected cells are also needed. Here, we report methods used to grow SARS-CoV-2 in multiple cell lines and to measure virus infectivity by plaque assay using either agarose or microcrystalline cellulose as an overlay as well as a SARS-CoV-2 specific focus forming assay. We also demonstrate effective inactivation by TRIzol, 10% neutral buffered formalin, beta propiolactone, and heat.</text>
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                <text>2020</text>
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                <text>coronavirus, virus, virology, SARS-CoV-2, plaque assay, inactivation</text>
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                <text>10.3390/v12060622</text>
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              <elementText elementTextId="81129">
                <text>Epidemiology and Health</text>
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            <name>Publisher</name>
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              <elementText elementTextId="81130">
                <text>Korean Society of Epidemiology</text>
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              <elementText elementTextId="81131">
                <text>Microbiology</text>
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              <elementText elementTextId="81133">
                <text>Michael Wink</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="81134">
                <text>Many plants produce secondary metabolites (PSMs) with antiviral activities. Among the antiviral PSMs, lipophilic terpenoids in essential oils can disturb the lipid envelope of viruses. Phenols and polyphenols (flavonoids, rosmarinic acid and tannins) attack viral proteins present in the viral membrane or inside the virus particle. Both phenolics and essential oils are active against free viral particles but not—or to a lesser degree—after a virus has entered a host cell. Another group of PSMs is directed against DNA or RNA. These are DNA intercalators such as sanguinarine, berberine, emetine and other isoquinoline alkaloids, ß-carboline, and quinoline alkaloids such as quinine, cinchonine, dictamine and skimmianine. The DNA intercalators stabilize double-stranded nucleic acids and inhibit the replication, transcription, and translation of genetic material. These alkaloids can inhibit viral development and viral replication in cells, as shown for SARS-CoV-1 and other viruses. Since chloroquine (which is also a DNA intercalator and a chemical derivative of the alkaloid quinine) is apparently clinically helpful against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, it is assumed that intercalating alkaloids, or the medicinal plants producing them, may be interesting candidates for the development of new antiviral drugs for the treatment of coronavirus disease 2019 (COVID-19).</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="81135">
                <text>2020</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="81136">
                <text>polyphenols, essential oil, Plant secondary metabolites, intercalating alkaloids, inhibition of polymerases, inhibition of protein biosynthesis</text>
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            </elementTextContainer>
          </element>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="81137">
                <text>10.3390/d12050175</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="81138">
                <text>Epidemiology and Health</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="81139">
                <text>Korean Society of Epidemiology</text>
              </elementText>
            </elementTextContainer>
          </element>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="81140">
                <text>Biology (General)</text>
              </elementText>
            </elementTextContainer>
          </element>
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            <element elementId="50">
              <name>Title</name>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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            </element>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="81141">
                <text>Umanesimo Digitale e Bene Comune? Linee guida e riflessioni per una salvezza possibile / Digital humanities and Commons: guidelines and recflections for a possible salvation</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="81142">
                <text>Ramona Quattrini, Paolo Clini</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="81143">
                <text>Il COVID ha evidenziato in maniera drammatica la condizione di totale fragilità della cultura e, in particolare, del nostro patrimonio artistico e storico, tangibile e intangibile. Una fragilità determinata sostanzialmente dall’assenza di relazioni, di cui invece il patrimonio vive nel susseguirsi storico delle società che lo conservano e lo condividono. Ai tempi del COVID, in cui tutti i musei, i siti archeologici e i luoghi della cultura erano chiusi, si è posta con urgenza la riflessione su come mantenere vive queste relazioni, attraverso il digitale. L’articolo tratteggia riflessioni teoriche e metodologiche per un manifesto di buone pratiche operative e scientifiche, a partire dalle numerose esperienze condotte in ambito di Umanesimo Digitale. Vengono esplicitati i quattro passaggi, intimamente connessi, su cui far leva per una filiera digitale consapevole e sostenibile: digitalizzazione scientifica, nuove forme di interazione virtuale, misurazione del gradimento dei pubblici, formazione di nuove competenze.  The pandemic crisis dramatically highlighted the fragility of culture and, in particular, of our tangible and intangible, artistic and historical heritage. A fragility determined substantially by the absence of relations, of which the heritage lives on in the historical succession of the societies that preserve and share it. In the days of Covid, when all museums, archaeological sites and places of culture were closed, there was an urgent need to reflect on how to keep these relationships alive, through digital technologies. The article outlines theoretical and methodological reflections for a manifesto of good operative and scientific practices, starting from several experiences conducted in the field of Digital Humanities. Four closely connected steps on which to leverage for a conscious and sustainable digital supply chain are explained: scientific digitization, new forms of virtual interaction, measurement of public acceptance, training of new skills.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="81144">
                <text>2020</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="81145">
                <text>10.13138/2039-2362/2529</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="81146">
                <text>Epidemiology and Health</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="81147">
                <text>Korean Society of Epidemiology</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="81148">
                <text>Auxiliary sciences of history, Arts in general</text>
              </elementText>
            </elementTextContainer>
          </element>
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  <item itemId="9756" public="1" featured="0">
    <fileContainer>
      <file fileId="9756">
        <src>https://www.socictopen.socict.org/files/original/359087b3964e8f742fe0a8e607cf952a.pdf</src>
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          <elementContainer>
            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="1">
                  <text>Coronavirus</text>
                </elementText>
              </elementTextContainer>
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            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
                </elementText>
              </elementTextContainer>
            </element>
          </elementContainer>
        </elementSet>
      </elementSetContainer>
    </collection>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="81149">
                <text>Indonesian Government’s COVID-19 Measures, January–May 2020: Late Response and Public Health Securitization</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="81150">
                <text>Tangguh Chairil</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="81151">
                <text>The Indonesian government’s measures to control the coronavirus disease 2019 (COVID-19) pandemic can be characterized by late response due to initial de-securitization of the issue, and later securitization that limits its very efficacy in restricting the spread of the pandemic. This article uses securitization theory to analyze the government’s measures to control the COVID-19 pandemic and discusses how the government’s increasing reliance on military figures and national security agencies influences the measures used to control the COVID-19 pandemic. This study finds that initially, the government seemed to be trying to de-securitize the issue, denying warnings that the virus might have existed undetected in Indonesia. Then, after the first cases were confirmed in March 2020, the government responded by securitizing the issue. The delay in the government’s response to COVID-19 caused the audience to not fully accept the government’s securitization efforts because public trust in the government’s measures was already low, while the means of emergency action taken by the government against the threat of COVID-19 are also limited. The government has also been overly reliant on influential military figures and national security agencies. The government also tended to downgrade the threats, lack transparency, and even use the pandemic to crack down on anti-government smears. This article concludes that the government needs to change their approach to COVID-19 measures and prioritize the human security dimension by not downgrading the threats and upholding transparency.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="81152">
                <text>2021</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="81153">
                <text>coronavirus, covid-19, Indonesia, Securitization, public health security</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="81154">
                <text>10.22146/jsp.55863</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="81155">
                <text>JSP: Jurnal Ilmu Sosial dan Ilmu Politik</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="81156">
                <text>Universitas Gadjah Mada</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="81157">
                <text>Social sciences (General), Political science (General)</text>
              </elementText>
            </elementTextContainer>
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  <item itemId="9757" public="1" featured="0">
    <fileContainer>
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        <src>https://www.socictopen.socict.org/files/original/db45b2f9d51ffd05b140dbc12d574ba3.pdf</src>
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          <name>Dublin Core</name>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                <elementText elementTextId="1">
                  <text>Coronavirus</text>
                </elementText>
              </elementTextContainer>
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            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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              </elementTextContainer>
            </element>
          </elementContainer>
        </elementSet>
      </elementSetContainer>
    </collection>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="81158">
                <text>Hospital Pharmacy in the multidisciplinary team of COVID inpatient units</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="81159">
                <text>María Victoria Gil-Navarro, Rafael Luque-Márquez</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="81160">
                <text>Since the implementation of the Antimicrobial Therapy Optimization Programme, hospital pharmacy specialists have collaborated with infectious disease specialists  on a regular basis in most hospitals in Spain.  Cooperation between these professionals ensures the integrated management of patients with infectious diseases  and the appropriate use of antimicrobials in  hospitals. The COVID-19 pandemic forced hospital pharmacists to abruptly  suspend all their structured activities and concentrate on the health crisis.  Realtime information sharing between different medicine specialties is an  effective strategy to generate and maintain treatment protocols adapted to each center, with continuous evidence-based modifications as new publications appear. Hospital pharmacies had to reorganize their activities  to respond to the pandemic. On the one side were patients with COVID-19, and on  the other were routine hospital pharmacy tasks, with the added difficulty  of  adapting to individual protection measures. New communication and  collaboration strategies were adopted. Protocols were established for the  management of COVID-19 patients, with continuous changes, special  medications had to be prepared and distributed, circuits were designed for the  home-  or institution-based care of patients, internal circuits were created to  minimize the movements of hospital staff and professionals caring for COVID-19  patients. The most effective antiviral drug and anti inflammatory therapy  remains elusive. In this scenario, hospital pharmacists emerge as a key  player,  as they have a deep understanding of the mechanisms of action of drugs and  potential interactions. In a setting where experimental drugs preferably  tested in clinical trials are being used, the role of hospital pharmacists in interdisciplinary  teams has become essential for the optimization of clinical  outcomes.</text>
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          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="81161">
                <text>2020</text>
              </elementText>
            </elementTextContainer>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="81162">
                <text>infectious disease, covid-19, Hospital Pharmacy Service, Multidisciplinary team</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="81163">
                <text>10.7399/fh.11517</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="81164">
                <text>Farmacia Hospitalaria</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="81165">
                <text>Grupo Aula Médica</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="81166">
                <text>Medicine, Pharmacy and materia medica</text>
              </elementText>
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  <item itemId="9758" public="1" featured="0">
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      <file fileId="9758">
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          <elementContainer>
            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                <elementText elementTextId="1">
                  <text>Coronavirus</text>
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              </elementTextContainer>
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            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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              </elementTextContainer>
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    <itemType itemTypeId="1">
      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="81167">
                <text>N-Acetylcysteine to Combat COVID-19: An Evidence Review</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="81168">
                <text>Shi Z, Puyo CA</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="81169">
                <text>Zhongcheng Shi,1,2 Carlos A Puyo3 1Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, USA; 2Department of Pathology, Texas Children&amp;rsquo;s Hospital, Houston, TX, USA; 3Department of Anesthesia and Critical Care, Holy Family Hospital, Steward Health Care, Methuen, MA, USACorrespondence: Zhongcheng Shi Tel +1- 832-824-0814Email zhongchs@bcm.eduAbstract: The novel coronavirus disease (COVID-19) is caused by a virus (SARS-Cov-2) and is known for inducing multisystem organ dysfunction associated with significant morbidity and mortality. Current therapeutic strategies for COVID-19 have failed to effectively reduce mortality rate, especially for elderly patients. A newly developed vaccine against SARS-Cov-2 has been reported to induce the production of neutralizing antibodies in young volunteers. However, the vaccine has shown limited benefit in the elderly, suggesting an age-dependent immune response. As a result, exploring new applications of existing medications could potentially provide valuable treatments for COVID-19. N-acetylcysteine (NAC) has been used in clinical practice to treat critically ill septic patients, and more recently for COVID-19 patients. NAC has antioxidant, anti-inflammatory and immune-modulating characteristics that may prove beneficial in the treatment and prevention of SARS-Cov-2. This review offers a thorough analysis of NAC and discusses its potential use for treatment of COVID-19.Keywords: N-acetylcysteine, SARS-Cov-2, COVID-19</text>
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          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="81170">
                <text>2020</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>covid-19, SARS-CoV-2, n-acetylcysteine</text>
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                <text>Biotemas</text>
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            <name>Publisher</name>
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                <text>Universidade Federal de Santa Catarina</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Medicine (General)</text>
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        <src>https://www.socictopen.socict.org/files/original/38b236ed3f3355d933910d078ab8db27.pdf</src>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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              <name>Description</name>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>A Tale of Two Viruses: The Distinct Spike Glycoproteins of Feline Coronaviruses</text>
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            <name>Creator</name>
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                <text>Javier  A. Jaimes, Jean  K. Millet, Alison  E. Stout, Nicole  M. André, Gary  R. Whittaker</text>
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                <text>Feline coronavirus (FCoV) is a complex viral agent that causes a variety of clinical manifestations in cats, commonly known as feline infectious peritonitis (FIP). It is recognized that FCoV can occur in two different serotypes. However, differences in the S protein are much more than serological or antigenic variants, resulting in the effective presence of two distinct viruses. Here, we review the distinct differences in the S proteins of these viruses, which are likely to translate into distinct biological outcomes. We introduce a new concept related to the non-taxonomical classification and differentiation among FCoVs by analyzing and comparing the genetic, structural, and functional characteristics of FCoV and the FCoV S protein among the two serotypes and FCoV biotypes. Based on our analysis, we suggest that our understanding of FIP needs to consider whether the presence of these two distinct viruses has implications in clinical settings.</text>
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                <text>2020</text>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>feline infectious peritonitis, spike protein, feline coronavirus, genetic characterization, serotype</text>
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            <name>Identifier</name>
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                <text>10.3390/v12010083</text>
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                <text>Epidemiology and Health</text>
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            <name>Publisher</name>
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                <text>Korean Society of Epidemiology</text>
              </elementText>
            </elementTextContainer>
          </element>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Microbiology</text>
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