987 10 20655 https://www.socictopen.socict.org/files/original/e5d27222b8d74398b13b6f84d0e52150.pdf fd7a21082d0fe096bca7db882a1277d8 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource How Will We Dine? Prospective Shifts in International Haute Cuisine and Innovation beyond Kitchen and Plate Creator An entity primarily responsible for making the resource Victor Tiberius, Nele Schwark, Manuela Fabro Description An account of the resource Haute cuisine, the cooking style for fine dining at gourmet restaurants, has changed over the last decades and can be expected to evolve in the upcoming years. To engage in foresight, the purpose of this study is to identify a plausible future trend scenario for the haute cuisine sector within the next five to ten years, based on today’s chefs’ views. To achieve this goal, an international, two-stage Delphi study was conducted. The derived scenario suggests that the coronavirus disease 2019 (COVID-19) pandemic will lead to significant restaurant bankruptcies and will raise creativity and innovation among the remaining ones. It is expected that haute cuisine tourism will grow and that menu prices will differ for customer segments. More haute cuisine restaurants will open in Asia and America. Local food will remain a major trend and will be complemented by insect as well as plant-based proteins and sophisticated nonalcoholic food pairings. Restaurant design and the use of scents will become more relevant. Also, private dining and fine dining at home will become more important. The scenario also includes negative projections. These findings can serve as a research agenda for future research in haute cuisine, including the extension of the innovation lens towards the restaurant and the business model. Practical implications include the necessity for haute cuisine restaurants to innovate to cope with increasing competition in several regions. Customers should be seen as co-creators of the value of haute cuisine. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource innovation, Delphi method, haute cuisine, Michelin Star, fine dining, high gastronomy Identifier An unambiguous reference to the resource within a given context 10.3390/foods9101369 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Chemical technology https://www.socictopen.socict.org/files/original/cfaf99881ebd11b78ab92b3229dc35ab.pdf e325a512d6c6b1fd339c457a695c4587 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The Spatial Dimension of COVID-19: The Potential of Earth Observation Data in Support of Slum Communities with Evidence from Brazil Creator An entity primarily responsible for making the resource Patricia Lustosa Brito, Monika Kuffer, Mila Koeva, Julio Cesar Pedrassoli, Jiong Wang, Federico Costa, Anderson Dias de Freitas Description An account of the resource The COVID-19 health emergency is impacting all of our lives, but the living conditions and urban morphologies found in poor communities make inhabitants more vulnerable to the COVID-19 outbreak as compared to the formal city, where inhabitants have the resources to follow WHO guidelines. In general, municipal spatial datasets are not well equipped to support spatial responses to health emergencies, particularly in poor communities. In such critical situations, Earth observation (EO) data can play a vital role in timely decision making and can save many people’s lives. This work provides an overview of the potential of EO-based global and local datasets, as well as local data gathering procedures (e.g., drones), in support of COVID-19 responses by referring to two slum areas in Salvador, Brazil as a case study. We discuss the role of datasets as well as data gaps that hinder COVID-19 responses. In Salvador and other low- and middle-income countries’ (LMICs) cities, local data are available; however, they are not up to date. For example, depending on the source, the population of the study areas in 2020 varies by more than 20%. Thus, EO data integration can help in updating local datasets and in the acquisition of physical parameters of poor urban communities, which are often not systematically collected in local surveys. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Pandemic, urban health, informal settlements, urban remote sensing, deprived areas Identifier An unambiguous reference to the resource within a given context 10.3390/ijgi9090557 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Geography (General) https://www.socictopen.socict.org/files/original/3509709ea6384ff15854da14dacfec40.pdf d0fd5f6236fb7609655baa6a63c164a1 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Evaluation of the Effect of Environmental Parameters on the Spread of COVID-19: A Fuzzy Logic Approach Creator An entity primarily responsible for making the resource Mohammad Asaduzzaman Chowdhury, Quazi Zobaer Shah, Mohammod Abul Kashem, Abdus Shahid, Nasim Akhtar Description An account of the resource In recent months, the world has experienced the outbreak and spread of a new infectious disease, COVID-19. The spread of this disease has been so severe, and even many developed countries have struggled to manage this situation. However, some countries, such as China and Australia, have shown success in taking effective steps towards tackling the crisis. So far, some preventive measures to contain the spread of infection have emerged. Numerous studies have been undertaken worldwide in parallel in order to develop strategies to contain the virus, as well as to determine climatic or atmospheric conditions favoring COVID-19 spread. In this research, an artificial intelligence (AI) system has been adopted to assess the effective role of various environmental conditions in the spread of COVID-19. Temperature, relative humidity (RH), and UV index (UVI) of some affected countries were considered as input parameters while the total number of infected people is taken as the output variable. After plotting all available data as linguistic variables, a relationship is established between temperature, RH, UVI, and the number of infected people. From the surface graph, it can be stated that in addition to UVI, temperature and RH have a significant impact on the number of affected people. The maximum and minimum temperatures as well as other parameters are considered on the basis of mean values. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.1155/2020/8829227 Source A related resource from which the described resource is derived Advances in Fuzzy Systems Publisher An entity responsible for making the resource available Hindawi Limited Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Electrical engineering. Electronics. Nuclear engineering, Computer software https://www.socictopen.socict.org/files/original/8dff07a737a884f63adeb29693e48a1f.pdf c09c0aa28bb1d9bd6281287d0c7be7fd Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Containment of COVID-19 in Ethiopia and implications for tuberculosis care and research Creator An entity primarily responsible for making the resource Hussen Mohammed, Lemessa Oljira, Kedir Teji Roba, Getnet Yimer, Abebaw Fekadu, Tsegahun Manyazewal Description An account of the resource Abstract Background The coronavirus disease 2019 (COVID-19) has emerged as a global health and economic security threat with staggering cumulative incidence worldwide. Given the severity of projections, hospitals across the globe are creating additional critical care surge capacity and limiting patient routine access to care for other diseases like tuberculosis (TB). The outbreak fuels panic in sub-Saharan Africa where the healthcare system is fragile in withstanding the disease. Here, we looked over the COVID-19 containment measures in Ethiopia in context from reliable sources and put forth recommendations that leverage the health system response to COVID-19 and TB. Main text Ethiopia shares a major proportion of the global burden of infectious diseases, while the patterns of COVID-19 are still at an earlier stage of the epidemiology curve. The Ethiopian government exerted tremendous efforts to curb the disease. It limited public gatherings, ordered school closures, directed high-risk civil servants to work from home, and closed borders. It suspended flights to 120 countries and restricted mass transports. It declared a five-month national state of emergency and granted a pardon for 20 402 prisoners. It officially postponed parliamentary and presidential elections. It launched the ‘PM Abiy-Jack Ma initiative’, which supports African countries with COVID-19 diagnostics and infection prevention and control commodities. It expanded its COVID-19 testing capacity to 38 countrywide laboratories. Many institutions are made available to provide clinical care and quarantine. However, the outbreak still has the potential for greater loss of life in Ethiopia if the community is unable to shape the regular behavioral and sociocultural norms that would facilitate the spread of the disease. The government needs to keep cautious that irregular migrants would fuel the disease. A robust testing capacity is needed to figure out the actual status of the disease. The pandemic has reduced TB care and research activities significantly and these need due attention. Conclusions Ethiopia took several steps to detect, manage, and control COVID-19. More efforts are needed to increase testing capacity and bring about behavioral changes in the community. The country needs to put in place alternative options to mitigate interruptions of essential healthcare services and scientific researches of significant impact. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource coronavirus, Public health, covid-19, Ethiopia, Tuberculosis, Containment Identifier An unambiguous reference to the resource within a given context 10.1186/s40249-020-00753-9 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Public aspects of medicine https://www.socictopen.socict.org/files/original/34c13332111bc931c7627f0aab0f7126.pdf f4c209b2e70e68d17a3df350ffb65e14 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Excess Mortality Estimation During the COVID-19 Pandemic: Preliminary Data from Portugal Creator An entity primarily responsible for making the resource Paulo Jorge Nogueira, Miguel de Araújo Nobre, Paulo Jorge Nicola, Cristina Furtado, António Vaz Carneiro Description An account of the resource Introduction: Portugal is experiencing the effects of the COVID-19 pandemic since March 2020. All-causes mortality in Portugal increased during March and April 2020 compared to previous years, but this increase is not explained by COVID-19 reported deaths. The aim of this study was to analyze and consider other criteria for estimating excessive all-causes mortality during the early COVID-19pandemic period. Material and Methods: Public data was used to estimate excess mortality by age and region between March 1 and April 22, proposing baselines adjusted for the lockdown period. Results: Despite the inherent uncertainty, it is safe to assume an observed excess mortality of 2400 to 4000 deaths. Excess mortality was associated with older age groups (over age 65). Discussion: The data suggests a ternary explanation for early excess mortality: COVID-19, non-identified COVID-19 and decrease in access to healthcare. The estimates have implications in terms of communication of non-pharmaceutical actions, for research, and to healthcare professionals. Conclusion: The excess mortality occurred between March 1 and April 22 was 3.5- to 5-fold higher than what can be explained by the official COVID-19 deaths. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource coronavirus, mortality, coronavirus infections, Disease Outbreaks, pandemics, Portugal Identifier An unambiguous reference to the resource within a given context 10.20344/amp.13928 Source A related resource from which the described resource is derived Acta Médica Portuguesa Publisher An entity responsible for making the resource available Ordem dos Médicos Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine, Medicine (General) https://www.socictopen.socict.org/files/original/db8d44241750d62af26b34b1a9dae467.pdf 37fe7f7737b48dc1f635e4acae6b44e3 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Interaction of Hydroxychloroquine with Pharmacokinetically Important Drug Transporters Creator An entity primarily responsible for making the resource Johanna Weiss, Walter E. Haefeli, Gzona Bajraktari-Sylejmani Description An account of the resource (1) Background: Hydroxychloroquine is used to treat malaria and autoimmune diseases, and its potential use against COVID-19 is currently under investigation. Thus far, information on interactions of hydroxychloroquine with drug transporters mediating drug-drug interactions is limited. We assessed the inhibition of important efflux (P-glycoprotein (P-gp), breast cancer resistance protein (BCRP)) and uptake transporters (organic anion transporting polypeptide (OATP)-1B1, OATP1B3, OATP2B1) by hydroxychloroquine, tested its P-gp and BCRP substrate characteristics, and evaluated the induction of pharmacokinetically relevant genes regulated by the nuclear pregnane X (PXR) (CYP3A4, ABCB1) and aryl hydrocarbon receptor (AhR) (CYP1A1, CYP1A2). (2) Methods: Transporter inhibition was evaluated in transporter over-expressing cell lines using fluorescent probe substrates. P-gp and BCRP substrate characteristics were assessed by comparing growth inhibition of over-expressing and parental cell lines. Possible mRNA induction was analysed in LS180 cells by quantitative real-time PCR. (3) Results: Hydroxychloroquine did not inhibit BCRP or the OATPs tested but inhibited P-gp at concentrations exceeding 10 µM. P-gp overexpressing cells were 5.2-fold more resistant to hydroxychloroquine than control cells stressing its substrate characteristics. Hydroxychloroquine did not induce genes regulated by PXR or AhR. (4) Conclusions: This is the first evidence that hydroxychloroquine’s interaction potential with drug transporters is low, albeit bioavailability of simultaneously orally administered P-gp substrates might be increased by hydroxychloroquine. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Hydroxychloroquine, inhibition, P-glycoprotein, induction, drug-drug interaction, drug transporters Identifier An unambiguous reference to the resource within a given context 10.3390/pharmaceutics12100919 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Pharmacy and materia medica https://www.socictopen.socict.org/files/original/fe17598daeaf6c42c7f520d17b447377.pdf fec047588dd778e6970c3d514b30e56d Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Impact of Comorbidities on SARS-CoV-2 Viral Entry-Related Genes Creator An entity primarily responsible for making the resource Prabhatchandra Dube, Deepak Malhotra, David J. Kennedy, Steven T. Haller, Joshua D. Breidenbach, Subhanwita Ghosh, Belal N. Abdullah, Nikolai N. Modyanov, Lance D. Dworkin Description An account of the resource Viral entry mechanisms for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are an important aspect of virulence. Proposed mechanisms involve host cell membrane-bound angiotensin-converting enzyme 2 (ACE2), type II transmembrane serine proteases (TTSPs), such as transmembrane serine protease isoform 2 (TMPRSS2), lysosomal endopeptidase Cathepsin L (CTSL), subtilisin-like proprotein peptidase furin (FURIN), and even potentially membrane bound heparan sulfate proteoglycans. The distribution and expression of many of these genes across cell types representing multiple organ systems in healthy individuals has recently been demonstrated. However, comorbidities such as diabetes and cardiovascular disease are highly prevalent in patients with Coronavirus Disease 2019 (COVID-19) and are associated with worse outcomes. Whether these conditions contribute directly to SARS-CoV-2 virulence remains unclear. Here, we show that the expression levels of ACE2, TMPRSS2 and other viral entry-related genes, as well as potential downstream effector genes such as bradykinin receptors, are modulated in the target organs of select disease states. In tissues, such as the heart, which normally express ACE2 but minimal TMPRSS2, we found that TMPRSS2 as well as other TTSPs are elevated in individuals with comorbidities compared to healthy individuals. Additionally, we found the increased expression of viral entry-related genes in the settings of hypertension, cancer, or smoking across target organ systems. Our results demonstrate that common comorbidities may contribute directly to SARS-CoV-2 virulence and we suggest new therapeutic targets to improve outcomes in vulnerable patient populations. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, SARS-CoV-2, comorbidities, renin-angiotensin-aldosterone system, Bradykinin, tropism Identifier An unambiguous reference to the resource within a given context 10.3390/jpm10040146 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine https://www.socictopen.socict.org/files/original/a5079857e7c84e82e7f6a803f2652d67.pdf e9fecd4727a11d6fc727f7fff16dd6ea Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource How Did Chinese Government Implement Unconventional Measures Against COVID-19 Pneumonia Creator An entity primarily responsible for making the resource Yu X, Li N Description An account of the resource Xiang Yu,1 Na Li2,3 1School of Public Affairs, Fujian Jiangxia University, Fuzhou, Fujian Province, People’s Republic of China; 2School of Law, Ningbo University, Ningbo, Zhejiang Province, People’s Republic of China; 3Research Academy of Belt and Road, Ningbo University, Ningbo, Zhejiang Province, People’s Republic of ChinaCorrespondence: Na LiNingbo University, 818st Fenghua Road Jiangbei, Ningbo 315211, People’s Republic of ChinaEmail nali321@126.comAbstract: In recent years, respiratory infectious diseases had continued to attack China, the recent outbreak of COVID-19 pneumonia had attracted worldwide attention. Through studying the literature, interpreting official documents, analyzing medical and social management data, we summarized and compared some powerful measures taken by the Chinese government, such as declaring emergency state, blocking down the epidemic center, prohibiting crowd gathering activities, forcing residents to wear masks, and mobilizing medical staff and products. We found that these unconventional measures, on the one hand, controlled the spread of the epidemic in China, and on the other hand, exposed some of China’s shortcomings in biosafety, food safety, public health input, and emergency system construction. This paper also recommends that other countries should take strict isolation measures as early as possible when fighting COVID-19 epidemics, and also mobilize citizens to strengthen self-protection.Keywords: COVID-19, anti-epidemic, risk, legality Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, anti-epidemic, risk；legality Source A related resource from which the described resource is derived Biotemas Publisher An entity responsible for making the resource available Universidade Federal de Santa Catarina Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Public aspects of medicine https://www.socictopen.socict.org/files/original/7aeaa5a5fc08061e2ecb1286bf29d350.pdf ecfe5959c8990e0228fdfd9fd501fce6 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Türkçe Eğitiminde Dijital Yetkinlik Kavramının Farklı Değişkenler Açısından İncelenmesi Creator An entity primarily responsible for making the resource Hulusi GEÇGEL, Fatih KANA, Duygu EREN Description An account of the resource Dünyada ve Türkiye’de devam eden COVİD 19 salgını süresince araştıran, düşünen, üreten bireyin yanı sıra dijital yetkinliğe sahip bireylerin önemi ortaya çıkmıştır. Özellikle öğrencilerin okula gidememesi ve derslerin uzaktan yapılması süresince, teknolojik donanım eksikliği, içerik eksikliği ve bireylerin dijital yetkinlik eksikliği ön plana çıkmıştır. Bu çalışmanın amacı ortaokul öğrencilerinin dijital yetkinlik becerileriyle ilgili öğretmen görüşlerini belirlemektir. Bu amaç doğrultusunda araştırmada nitel araştırma yöntemlerinden durum çalışması deseni kullanılmıştır. Araştırmanın çalışma grubunu Türkiye’nin batısında yer alan bir devlet ortaokulunda görev yapan öğretmenler oluşturmaktadır. Araştırmanın veri analizinde içerik analizi yöntemi kullanılmıştır. Araştırmada veri toplama aracı olarak yarı yapılandırılmış görüşme formu kullanılmıştır. Okullarda FATİH projesinden dolayı etkileşimli tahtaların yeteri kadar bulunduğu ama bilgisayarların ihtiyacı karşılayacak düzeyde ve dijital çağa uygun olmadığı görülmüştür. Öğrencilerin proje merkezli değil de sınav merkezli yetiştiği, bu yüzden teknolojik araçlara yönelmede problem yaşandığı görülmüştür. Dünyayı etkisine alan COVİD 19 salgını sürecinde öğretmen ve öğrencilerin dijital yetkinlikler açısından yetiştirilmesi gerektiği görülmüştür. Bu araştırmada dijital yetkinlik açısından öğretmenlerin, öğrencilerin, programların ve kitapların yeniden değerlendirilmesi gerektiği sonucuna ulaşılmıştır. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, EBA, Fatih projesi, dijital yetkinlik, dijital öğrenme Identifier An unambiguous reference to the resource within a given context 10.16916/aded.742352 Source A related resource from which the described resource is derived Ana Dili Eğitimi Dergisi Publisher An entity responsible for making the resource available Mehmet KURUDAYIOĞLU Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Education https://www.socictopen.socict.org/files/original/d498057f29ae23794ee68773a44083a5.pdf f48aa948701b45066dd304d43db6dbf5 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource A Message from the Human Placenta: Structural and Immunomodulatory Defense against SARS-CoV-2 Creator An entity primarily responsible for making the resource Nina-Naomi Kreis, Andreas Ritter, Frank Louwen, Juping Yuan Description An account of the resource The outbreak of the coronavirus disease 2019 (COVID-19) pandemic has caused a global public health crisis. Viral infections may predispose pregnant women to a higher rate of pregnancy complications, including preterm births, miscarriage, and stillbirth. Despite reports of neonatal COVID-19, definitive proof of vertical transmission is still lacking. In this review, we summarize studies regarding the potential evidence for transplacental transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), characterize the expression of its receptors and proteases, describe the placental pathology and analyze virus-host interactions at the maternal-fetal interface. We focus on the syncytium, the barrier between mother and fetus, and describe in detail its physical and structural defense against viral infections. We further discuss the potential molecular mechanisms, whereby the placenta serves as a defense front against pathogens by regulating the interferon type III signaling, microRNA-triggered autophagy and the nuclear factor-κB pathway. Based on these data, we conclude that vertical transmission may occur but rare, ascribed to the potent physical barrier, the fine-regulated placental immune defense and modulation strategies. Particularly, immunomodulatory mechanisms employed by the placenta may mitigate violent immune response, maybe soften cytokine storm tightly associated with severely ill COVID-19 patients, possibly minimizing cell and tissue damages, and potentially reducing SARS-CoV-2 transmission. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, SARS-CoV-2, Vertical transmission, miRNA, placenta, immune defense Identifier An unambiguous reference to the resource within a given context 10.3390/cells9081777 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General)