133 10 20655 https://www.socictopen.socict.org/files/original/772cb3ae2d5afb95619556e7c215eff1.pdf d9defc6570dfced4f2e27a9333ac0b9e Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Comparison of influenza disease burden in older populations of Hong Kong and Brisbane: the impact of influenza and pneumococcal vaccination Creator An entity primarily responsible for making the resource Lin Yang, King-Pan Chan, Chit-Ming Wong, Susan Shui Seng Chiu, Ricardo J. Soares Magalhães, Thuan-Quoc Thach, Joseph Syrial Malik Peiris, Archie C.A. Clements, Wenbiao Hu Description An account of the resource Abstract Background Influenza and pneumococcal vaccine uptake in the older population aged 65 years or over of Hong Kong dramatically increased since the 2003 SARS outbreak. This study is aimed to evaluate the impact of increased coverage of influenza and pneumococcal vaccines by comparing the change of disease burden in the older population of Hong Kong, with the burden in the older population of Brisbane with relatively high vaccine coverage in the past fifteen years. Methods Time series segmented regression models were applied to weekly numbers of cause-specific mortality or hospitalization of Hong Kong and Brisbane. Annual excess rates of mortality or hospitalization associated with influenza in the older population were estimated for the pre-SARS (reference period), post-SARS and post-pandemic period, respectively. The rate ratios (RRs) between these periods were also calculated to assess the relative change of disease burden. Results Compared to the pre-SARS period, excess rates of mortality associated with influenza during the post-SARS period in Hong Kong decreased for cardiorespiratory diseases (RR = 0.90, 95% CI 0.80, 1.01), stroke (RR = 0.74, 95% CI 0.50, 1.09), and ischemic heart diseases (RR = 0.45, 95% CI 0.34, 0.58). The corresponding RRs in Brisbane were 0.79 (95% CI 0.54, 1.15), 0.33 (0.13, 0.80), and 1.09 (0.62, 1.90), respectively. Only the mortality of ischemic heart diseases showed a greater reduction in Hong Kong than in Brisbane. During the post-pandemic period, excess rates of all-cause mortality increased in Hong Kong, but to a lesser extent than in Brisbane (RR = 1.41 vs 2.39). Conclusion A relative decrease (or less of an increase) of influenza disease burden was observed in the older population of Hong Kong after increased coverage of influenza and pneumococcal vaccines in this population, as compared to those of Brisbane where vaccination rates remained stable. The lack of significant findings in some disease categories highlights the challenges of evaluating the benefits of vaccination at the population level. Date A point or period of time associated with an event in the lifecycle of the resource 2019 Subject The topic of the resource influenza, disease burden, Mortality, Morbidity, elderly, vaccine Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/s12879-019-3735-7 Source A related resource from which the described resource is derived BMC Infectious Diseases Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases Language A language of the resource EN https://www.socictopen.socict.org/files/original/2e7bc9c41d9104ac1fc23cf908cc490e.pdf 44f75f4dc11fde4d73196b5ff5f2ab36 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Magnetic Nanotrap Particles Preserve the Stability of Venezuelan Equine Encephalitis Virus in Blood for Laboratory Detection Creator An entity primarily responsible for making the resource Ivan Akhrymuk, Shih-Chao Lin, Mei Sun, Anurag Patnaik, Caitlin Lehman, Louis Altamura, Timothy Minogue, Ben Lepene, Monique L. van Hoek, Kylene Kehn-Hall Description An account of the resource Most of the modern techniques used for identification of viral-induced disease are based on identification of viral antigens and/or nucleic acids in patient's blood. Diagnosis in the field or in remote locations can be challenging and alternatively samples are shipped to diagnostic labs for testing. Shipments must occur under controlled temperature conditions to prevent loss of sample integrity. We have tested the ability of magnetic Nanotrap® (NT) particles to improve stability and detection of Venezuelan equine encephalitis virus (VEEV), viral capsid protein, and viral genomic RNA in whole human blood at elevated temperature and prolonged storage conditions. NT particles have previously been shown to capture and enrich multiple pathogens including respiratory syncytial virus, influenza virus, coronavirus, and Rift Valley fever virus. Our study indicates that samples incubated with NT particles had detectable levels of infectious VEEV in blood equal to or greater than samples without NT treatment across all temperatures. Viral RNA detection was increased in the presence of NT particles at later time points (72 h) and higher temperature (40°C) conditions. Likewise, detection of VEEV capsid protein was enhanced in the presence of NT particles up to 72 h at 40°C. Finally, we intranasally infected C3H mice with TC-83, the live attenuated vaccine strain of VEEV, and demonstrated that NT particles could substantially increase the detection of VEEV capsid in infected blood incubated up to 72 h at 40°C. Samples without NT particles had undetectable capsid protein levels. Taken together, our data demonstrate the ability of NT particles to preserve and enable detection of VEEV in human and mouse blood samples over time and at elevated temperatures. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Alphavirus, diagnostics, Surveillance, Venezuelan equine encephalitis virus, nanotrap particles, nanoparticles Identifier An unambiguous reference to the resource within a given context DOI: 10.3389/fvets.2019.00509 Source A related resource from which the described resource is derived Frontiers in Veterinary Science Publisher An entity responsible for making the resource available Frontiers Media S.A. Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Veterinary medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/d1d203e5b0e39e498859afc225041fb4.pdf 5272fefc8a555439e4fd138a99707475 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource MiR-10a-5p-Mediated Syndecan 1 Suppression Restricts Porcine Hemagglutinating Encephalomyelitis Virus Replication Creator An entity primarily responsible for making the resource Shi-Yu Hu, Zi Li, Yungang Lan, Jiyu Guan, Kui Zhao, Dianfeng Chu, Gencheng Fan, YuGuang Guo, Feng Gao, Wenqi He Description An account of the resource Porcine hemagglutinating encephalomyelitis virus (PHEV) is a single-stranded RNA coronavirus that causes nervous dysfunction in the infected hosts and leads to widespread alterations in the host transcriptome by modulating specific microRNA (miRNA) levels. MiRNAs contribute to RNA virus pathogenesis by promoting antiviral immune response, enhancing viral replication, or altering miRNA-mediated host gene regulation. Thus, exploration of the virus–miRNA interactions occurring in PHEV-infected host may lead to the identification of novel mechanisms combating the virus life cycle or pathogenesis. Here, we discovered that the expression of miR-10a-5p was constitutively up-regulated by PHEV in both the N2a cells in vitro and mice brain in vivo. Treatment with miR-10a-5p mimics allowed miR-10a-5p enrichment and resulted in a significant restriction in PHEV replication, suggesting widespread negative regulation of the RNA virus infection by miR-10a-5p. The outcomes were also evidenced by miR-10a-5p inhibitor over-expression. Luciferase reporter, quantitative real-time PCR (qRT-PCR), and western blotting analysis further showed that Syndecan 1 (SDC1), a cell surface proteoglycan associated with host defense mechanisms, acts as a target gene of miR-10a-5p during PHEV infection. Naturally, siRNA-mediated knockdown of SDC1 leads to a reduction in viral replication, implying that SDC1 expression is likely a favorable condition for viral replication. Together, the findings demonstrated that the abundant miR-10a-5p leads to downstream suppression of SDC1, and it functions as an antiviral mechanism in the PHEV-induced disease, providing a potential strategy for the prevention and treatment of PHEV infection in the future work. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Porcine hemagglutinating encephalomyelitis virus, miR-10a-5p, Syndecan-1, Virus replication, antiviral mechanism Identifier An unambiguous reference to the resource within a given context DOI: 10.3389/fmicb.2020.00105 Source A related resource from which the described resource is derived Frontiers in Microbiology Publisher An entity responsible for making the resource available Frontiers Media S.A. Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology Language A language of the resource EN https://www.socictopen.socict.org/files/original/cebcaaab0db64769522abf911092593d.pdf 00a00475f0957adf625883ea0b967fd9 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Modern possibilities of acute rhinosinusites phytotherapy Creator An entity primarily responsible for making the resource V. M. Svistushkin, L. A. Toporkova Description An account of the resource Acute rhinosinusitis is one of the most frequent diseases that doctors of various specialties – therapists, family doctors, otorhynolaryngolosts face. Despite the huge armoury of drugs and therapeutic methods the search for the drug providing complex therapy of rhinosinusitis reducing the duration of this disease therapy remains of vital importance till now. Phytotherapy is successfully used for the complex therapy of acute rhinosinusites. This therapeutic method is based on use of herbs and complex drugs from them. Due to the fact that currently the problem of antibiotic resistance is widely spread, it has become possible to search for the complex drug with a high safety profile for effective therapy and avoidance of polypharmacy in case of SARS, rhinosinusites and other diseases of the upper respiratory tracts. Date A point or period of time associated with an event in the lifecycle of the resource 2016 Subject The topic of the resource acute rhinosinusitis, Phytotherapy, sinupret® Identifier An unambiguous reference to the resource within a given context DOI: 10.21518/2079-701X-2016-18-38-41 Source A related resource from which the described resource is derived Медицинский совет Publisher An entity responsible for making the resource available Remedium Group LLC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine Language A language of the resource RU https://www.socictopen.socict.org/files/original/0b17b6253d1004e618bde9d0e3a95176.pdf 2c266a10a3a85e985facf3329a1f1a94 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource COMPLEX THERAPY OF SARS AND FLU Creator An entity primarily responsible for making the resource M.G. Pozdnyakova, M.K. Erofeeva Description An account of the resource Respiratory viral infections of non-flu etiology – adenoviral infection, paraflu, RS-vioral infection etc. – account for the major share of SARS, up to 90%. The frequency of flu viruses infection makes up about 15% (type A – 12%, type B – 3%), paraflu viruses – up to 50%, adenoviruses – from 5 to 10%, RS-viruses – 4%, mycoplasma – 2.7%, enteroviruses – 1.2%. Combined infections make up about 23% of cases [1]. Date A point or period of time associated with an event in the lifecycle of the resource 2016 Subject The topic of the resource SARS, flu, antiviral effect, symptom relief Identifier An unambiguous reference to the resource within a given context DOI: 10.21518/2079-701X-2016-15-58-61 Source A related resource from which the described resource is derived Медицинский совет Publisher An entity responsible for making the resource available Remedium Group LLC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine Language A language of the resource RU https://www.socictopen.socict.org/files/original/a028886780581e7d73521183f15f31bf.pdf c6ef851e18170650a76c9e4e9e0b301a Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New possibilities of therapy and prevention of complications of infectious-inflammatory diseases of the upper respiratory tract Creator An entity primarily responsible for making the resource A. A. Krivopalov, S.V. Ryazantsev, V. A. Shatalov Description An account of the resource Abstract. SARS in the overwhelming majority of cases are the initial link in the chain of pathological changes developing in acute rhinosinusitis, contribute to the severe course of the inflammatory process, development of local, remote and generalized complications. One of the important reasons for the growth of pathology of respiratory organs is increase of the prevalence of secondary immunodeficiencies (SIDS).The purpose of the study is to assess the effectiveness of the drug ISMIGEN® (sublingual tablets) on the course and severity of acute exacerbations of chronic tonsillopharyngitis during the epidemiological season of acute respiratory infections. Study design. This study is a comparative randomized, prospective, cohort trial. All patients matching the inclusion criteria and included in the study were randomized into 2 groups by 30 persons in accordance with the plan of randomization. The duration of the observation period was 6 months.Conclusions. Use of the drug Ismigen® allows significantly reduction of the likelihood of development in the patient of relapse/ exacerbation of HTF/SARS, the development of moderate and severe forms of the disease, as well as the need for additional antibiotic therapy. Date A point or period of time associated with an event in the lifecycle of the resource 2016 Subject The topic of the resource infectious-inflammatory diseases of the upper respiratory tract, complications of chronic tonsillopharyngitis, bacterial lysates, ismigen® Identifier An unambiguous reference to the resource within a given context DOI: 10.21518/2079-701X-2016-18-24-32 Source A related resource from which the described resource is derived Медицинский совет Publisher An entity responsible for making the resource available Remedium Group LLC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine Language A language of the resource RU https://www.socictopen.socict.org/files/original/cfb75c1a739d081f5b6c75af780efc18.pdf b31ed6042f0475019afc96794ea7061c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Initial Cluster of Novel Coronavirus (2019-nCoV) Infections in Wuhan, China Is Consistent with Substantial Human-to-Human Transmission Creator An entity primarily responsible for making the resource Hiroshi Nishiura, Natalie M. Linton, Andrei R. Akhmetzhanov Description An account of the resource Reanalysis of the epidemic curve from the initial cluster of cases with novel coronavirus (2019-nCoV) in December 2019 indicates substantial human-to-human transmission. It is possible that the common exposure history at a seafood market in Wuhan originated from the human-to-human transmission events within the market, and the early, strong emphasis that market exposure indicated animal-to-human transmission was potentially the result of observer bias. To support the hypothesis of zoonotic origin of 2019-nCoV stemming from the Huanan seafood market, the index case should have had exposure history related to the market and the virus should have been identified from animals sold at the market. As these requirements remain unmet, zoonotic spillover at the market must not be overemphasized. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Epidemiology, transmissibility, zoonosis, cluster, exposure, Statistical inference Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/jcm9020488 Source A related resource from which the described resource is derived Journal of Clinical Medicine Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/934541192a1b45af6a343c5d16278080.pdf 1a407ab830882567bc48e3964d818da5 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Return of the Coronavirus: 2019-nCoV Creator An entity primarily responsible for making the resource Lisa E Gralinski, Vineet D. Menachery Description An account of the resource The emergence of a novel coronavirus (2019-nCoV) has awakened the echoes of SARS-CoV from nearly two decades ago. Yet, with technological advances and important lessons gained from previous outbreaks, perhaps the world is better equipped to deal with the most recent emergent group 2B coronavirus. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource 2019ncov, novel cov, Wuhan, wuhan pneumonia, coronavirus, Emerging viruses, SARS-CoV, MERS-CoV Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/v12020135 Source A related resource from which the described resource is derived Viruses Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology Language A language of the resource EN https://www.socictopen.socict.org/files/original/58f1f2c2529fbce242929f20048290b9.pdf 757f2b043d518cdcaca2dfeee6b81af6 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource A Tale of Two Viruses: The Distinct Spike Glycoproteins of Feline Coronaviruses Creator An entity primarily responsible for making the resource Javier A. Jaimes, Jean K. Millet, Alison E Stout, Nicole M André, Gary R. Whittaker Description An account of the resource Feline coronavirus (FCoV) is a complex viral agent that causes a variety of clinical manifestations in cats, commonly known as feline infectious peritonitis (FIP). It is recognized that FCoV can occur in two different serotypes. However, differences in the S protein are much more than serological or antigenic variants, resulting in the effective presence of two distinct viruses. Here, we review the distinct differences in the S proteins of these viruses, which are likely to translate into distinct biological outcomes. We introduce a new concept related to the non-taxonomical classification and differentiation among FCoVs by analyzing and comparing the genetic, structural, and functional characteristics of FCoV and the FCoV S protein among the two serotypes and FCoV biotypes. Based on our analysis, we suggest that our understanding of FIP needs to consider whether the presence of these two distinct viruses has implications in clinical settings. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Feline coronavirus, feline infectious peritonitis, spike protein, Serotype, Genetic characterization Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/v12010083 Source A related resource from which the described resource is derived Viruses Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology Language A language of the resource EN https://www.socictopen.socict.org/files/original/ed39d7ca00116a1b307efa383904b7e4.pdf 95c9853884e5d77759e469abcc776a4c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Effect of Information Disclosure Policy on Control of Infectious Disease: MERS-CoV Outbreak in South Korea Creator An entity primarily responsible for making the resource Jin-Won Noh, Ki-Bong Yoo, Young Dae Kwon, Jin Hyuk Hong, Ye Jin Lee, Ki Soo Park Description An account of the resource This study examined the effect of disclosing a list of hospitals with Middle East respiratory syndrome coronavirus (MERS-CoV) patients on the number of laboratory-confirmed MERS-CoV cases in South Korea. MERS-CoV data from 20 May 2015 to 5 July 2015 were from the Korean Ministry of Health & Welfare website and analyzed using segmented linear autoregressive error models for interrupted time series. This study showed that the number of laboratory-confirmed cases was increased by 9.632 on 5 June (p < 0.001). However, this number was significantly decreased following disclosure of a list of hospitals with MERS-CoV cases (Estimate = −0.699; p < 0.001). Disclosing the list of hospitals exposed to MERS-CoV was critical to the prevention of further infection. It reduced the number of confirmed MERS-CoV cases. Thus, providing accurate and timely information is a key to critical care response. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Middle East respiratory syndrome, MERS-CoV, infectious disease, prevention, information disclosure policy Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/ijerph17010305 Source A related resource from which the described resource is derived International Journal of Environmental Research and Public Health Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine Language A language of the resource EN