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Evidence for a centrosome-attracting body like structure in germ-soma segregation during early development, in the urochordate Oikopleura dioica
Abstract Background Germ cell formation has been investigated in sessile forms of tunicates. This process involves the release of a subset of maternal transcripts from the centrosome-attracting body (CAB) in the progenitor cells of the germ line.…
Position: 19307 (15 views)
Viral and atypical bacterial etiologies of severe acute respiratory infection (SARI) in Egyptian patients: epidemiological patterns and results from the sentinel surveillance study 2010–2014
Background Respiratory viral and atypical bacterial infections data in Egyptian patients are sparse. This study described the epidemiological pattern of viral and atypical bacteria as causes for severe acute respiratory infections (SARI) in…
Position: 9071 (27 views)
Comparison of viral and epidemiological profiles of hospitalized children with severe acute respiratory infection in Beijing and Shanghai, China
Abstract Background No comparison data have been reported on viral and epidemiological profiles of hospitalized children with severe acute respiratory infection (SARI) in Beijing or Shanghai, China. Methods We collected 700 nasopharyngeal aspirates…
Position: 13420 (22 views)
Interferon Regulatory Factor 3-Mediated Signaling Limits Middle-East Respiratory Syndrome (MERS) Coronavirus Propagation in Cells from an Insectivorous Bat
Insectivorous bats are speculated to be ancestral hosts of Middle-East respiratory syndrome (MERS) coronavirus (CoV). MERS-CoV causes disease in humans with thirty-five percent fatality, and has evolved proteins that counteract human antiviral…
Position: 14422 (21 views)
Ethical and Philosophical Considerations for Gain-of-Function Policy: The Importance of Alternate Experiments
The Department of Health and Human Services Framework for Guiding Funding Decisions about Proposed Research Involving Enhanced Potential Pandemic Pathogens (PPPs) contains a series of principles for governing the funding and conduct of…
Position: 12458 (23 views)
Two-Domains Control of a Buck Converter
In the design of a power converter, the maximum output voltage transient under load change is one of the main drivers. The ECSS-E-ST-20C imposes specific requirements on the power quality of a regulated bus, which result most of the time in the use…
Position: 12458 (23 views)
Identification of two mutation sites in spike and envelope proteins mediating optimal cellular infection of porcine epidemic diarrhea virus from different pathways
Abstract Entry of the α-coronavirus porcine epidemic diarrhea virus (PEDV) requires specific proteases to activate spike (S) protein for the membrane fusion of the virion to the host cell following receptor binding. Herein, PEDV isolate 85-7 could…
Position: 17160 (18 views)
Characteristics of the Life Cycle of Porcine Deltacoronavirus (PDCoV) In Vitro: Replication Kinetics, Cellular Ultrastructure and Virion Morphology, and Evidence of Inducing Autophagy
Porcine deltacoronavirus (PDCoV) causes severe diarrhea and vomiting in affected piglets. The aim of this study was to establish the basic, in vitro characteristics of the life cycle such as replication kinetics, cellular ultrastructure, virion…
Position: 16335 (19 views)
Sylvie Largeaud-Ortega, Ainsi soit-île. Littérature et anthropologie dans les Contes des mers du sud de Robert Louis Stevenson
Position: 15408 (20 views)
Viral respiratory tract infections in young children with cystic fibrosis: a prospective full-year seasonal study
Abstract Background Viral respiratory tract infections are common during early childhood. How they impact cystic fibrosis lung disease history in young children is poorly known. The principal aim of our study was to determinate respiratory tract…
Position: 17160 (18 views)