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A Unified Framework for the Infection Dynamics of Zoonotic Spillover and Spread.
A considerable amount of disease is transmitted from animals to humans and many of these zoonoses are neglected tropical diseases. As outbreaks of SARS, avian influenza and Ebola have demonstrated, however, zoonotic diseases are serious threats to…
Position: 8704 (27 views)
Molecular Design, Synthesis and Trypanocidal Activity of Dipeptidyl Nitriles as Cruzain Inhibitors.
A series of compounds based on the dipeptidyl nitrile scaffold were synthesized and assayed for their inhibitory activity against the T. cruzi cysteine protease cruzain. Structure activity relationships (SARs) were established using three, eleven and…
Position: 10223 (25 views)
Increased breadth and depth of cytotoxic T lymphocytes responses against HIV-1-B Nef by inclusion of epitope variant sequences.
Different vaccine approaches cope with HIV-1 diversity, ranging from centralized(1-4) to variability-encompassing(5-7) antigens. For all these strategies, a concern remains: how does HIV-1 diversity impact epitope recognition by the immune system? We…
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The Important Role of Lipid Raft-Mediated Attachment in the Infection of Cultured Cells by Coronavirus Infectious Bronchitis Virus Beaudette Strain.
Lipid raft is an important element for the cellular entry of some viruses, including coronavirus infectious bronchitis virus (IBV). However, the exact role of lipid rafts in the cellular membrane during the entry of IBV into host cells is still…
Position: 6323 (31 views)
One health: The interface between veterinary and human health
One Health is an emerging global key concept integrating human and animal health through international research and policy. The complex relationships between the human and animal have resulted in a human-animal-environment interface since…
Position: 7360 (29 views)
With Father Dumitru Stăniloae on Father Dumitru Stăniloae
Studiul „Cu Părintele Dumitru Stăniloae despre Părintele Dumitru Stăniloae” reprezintă o incursiune sumară în biografia şi opera celui care este considerat pe bună dreptate cel mai mare teolog al secolului al XX-lea. Titlul sus-menţionat a fost dat…
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Acinar Adenocarcinoma of Prostate with Predominant Ttf-1 Positive Intraductal Component
Intraductal carcinoma of prostate has been previously described in radical prostatectomies. It’s rarely encountered in needle biopsies in the absence of infiltrative carcinoma. But, both histogenesis and nomenclature of the lesion is still…
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New Data on Biota of Some Lakes in the Western Part of the Putorana Plateau
Species composition and abundance of zooplankton and zoobenthos of large Norilsk Lakes (Lama, Sobach’e) and Kutaramakan Lake in the western part of the Putorana plateau were studied in August-September of 2013–2014 after a long gap. Senecella…
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RIJEKA ZETA KAO POTENCIJAL ZA RAZVOJ SPORTSKO-REKREATIVNIH OBLIKA TURIZMA
Ba sic for re a li za tion of to u rist mo ve ments lays in me e ting cul tu ral and rec re a ti onal ne eds of po ten tial cu sto mers. If we know that lar gest num ber of to u rists re pre sents part of rec re a ti o nal ones, than is not hard to…
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An Investigation of Viral Agents in Patients Presenting with Flu-Like Symptoms
Flu, is an infectious disease caused by influenza viruses. Various different viruses, such as respiratory syncytial virus (RSV), parainfluenza virus, adenovirus, rhinovirus and coronavirus constitute infection with flulike symptoms. In our study, the…
Position: 14064 (21 views)