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The first few days of a SARS-CoV-2 infection viewed at single-cell resolution.
What transpires soon after inhaling Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the respiratory virus causing Coronavirus Disease 2019 (COVID-19)? Where does infection begin? What are the features of subsequent virus spread? How…
Position: 17985 (17 views)
How and When to End the COVID-19 Lockdown: An Optimization Approach
Countries around the world are in a state of lockdown to help limit the spread of SARS-CoV-2. However, as the number of new daily confirmed cases begins to decrease, governments must decide how to release their populations from quarantine as…
Position: 7101 (30 views)
How Prepared Is Africa for the COVID-19 Pandemic Response? The Case of Ethiopia
Lemi Belay Tolu,1 Alex Ezeh,2 Garumma Tolu Feyissa3 1Department of Obstetrics and Gynecology, Saint Paul Hospital Millennium Medical College, Addis Ababa, Ethiopia; 2Dornsife School of Public Health, Drexel University, Philadelphia, PA, USA;…
Position: 839 (66 views)
S1 Subunit of Spike Protein from a Current Highly Virulent Porcine Epidemic Diarrhea Virus Is an Important Determinant of Virulence in Piglets
Base on the sequence of S genes, which encode spike proteins, we previously identified three different types (North American, S INDEL, and S large-DEL types) of porcine epidemic diarrhea virus (PEDV) that have re-emerged in Japan since 2013. Based on…
Position: 6605 (31 views)
Genomic Characterization and Phylogenetic Classification of Bovine Coronaviruses Through Whole Genome Sequence Analysis
Bovine coronavirus (BCoV) is zoonotically transmissible among species, since BCoV-like viruses have been detected in wild ruminants and humans. BCoV causing enteric and respiratory disease is widespread in cattle farms worldwide; however, limited…
Position: 10564 (25 views)
Assessing the Risk of Cascading COVID-19 Outbreaks from Prison-to-Prison Transfers.
COVID-19 transmission has been widespread across the California prison system, and at least two of these outbreaks were caused by transfer of infected individuals between prisons. Risks of individual prison outbreaks due to introduction of the virus…
Position: 17141 (18 views)
Quantification of experimentally induced nucleotide conversions in high-throughput sequencing datasets
Abstract Background Methods to read out naturally occurring or experimentally introduced nucleic acid modifications are emerging as powerful tools to study dynamic cellular processes. The recovery, quantification and interpretation of such events in…
Position: 16292 (19 views)
Eight Weeks Later—The Unprecedented Rise of 3D Printing during the COVID-19 Pandemic—A Case Study, Lessons Learned, and Implications on the Future of Global Decentralized Manufacturing
The eruption of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (corona virus disease, COVID-19) in Wuhan, China, and its global spread has led to an exponentially growing number of infected patients, currently exceeding over 6.6…
Position: 1270 (59 views)
Serum neurofilament light chain (sNfL) values in a large cross-sectional population of children with asymptomatic to moderate COVID-19.
Serum neurofilament light chain (sNfL) is an established biomarker of neuro-axonal damage in multiple neurological disorders. Raised sNfL levels have been reported in adults infected with pandemic coronavirus disease 2019 (COVID-19). Levels in…
Position: 20544 (11 views)
