1553 10 20655 https://www.socictopen.socict.org/files/original/97acb521c98d638580ae1e6a7b8c5596.pdf 8cb59ea9240b182990014b899804db14 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Principales NTC y protocolos de caracterización en productos derivados de caña de azúcar Creator An entity primarily responsible for making the resource Leonardo Moreno-Chacón, Diego Suarez-Peñaranda Description An account of the resource Los productos derivados de la caña de azúcar (Saccharum officinarum L) conforman una de las agroindustrias rurales de mayor tradición en Colombia. Con el fin de establecer los principales indicadores y protocolos que permitan la caracterización bromatológica, fitoquímica y antioxidante de productos derivados de S. officinarum, se realizó un rastreo bibliográfico a través de la base documental del Icontec y Scopus, en el periodo comprendido entre enero de 1990 y febrero de 2021. Lo anterior, bajo lineamientos que permitieran establecer un panorama mundial sobre las tendencias de investigación y desarrollo, análisis de productos finales e identificación de los principales protocolos normalizados y no normalizados. Fue así como se lograron identificar las principales NTC (Normas Técnicas Colombianas) y los protocolos más empleados para la cuantificación de los indicadores fisicoquímicos y de algunos metabolitos de interés, confirmando y estableciendo sus efectos positivos para la salud animal y humana, como potenciador inmunológico, antitóxico, citoprotector, anticariógeno y antioxidante. Adicionalmente, se logró determinar que los metales pesados (plomo, mercurio, cadmio, arsénico), furfural, 5-hidroximetilfurfural y acrilamida son los principales contaminantes sobre los cuales se debe establecer una estrategia de mitigación. Con esto, se hace evidente la necesidad de generar una política nacional que posibilite cuantificar los indicadores fisicoquímicos exigidos, el contenido de compuestos bioactivos y la presencia de contaminantes peligrosos en los productos derivados de la caña de azúcar, con el fin de dar cumplimiento a la normativa legal para la distribución y comercialización de productos azucarados en el mercado nacional e internacional y, por qué no, iniciar su diversificación. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource Acrilamida, Metales pesados, Panela, Saccharum officinarum L, anticancerígeno, antioxidante Identifier An unambiguous reference to the resource within a given context 10.23850/22565035.3631 Source A related resource from which the described resource is derived Informador Técnico Publisher An entity responsible for making the resource available Servicio Nacional de Aprendizaje SENA Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Engineering (General). Civil engineering (General), Technology (General) Relation A related resource <a href="http://revistas.sena.edu.co/index.php/inf_tec/article/view/3631" target="_blank" rel="noreferrer noopener">http://revistas.sena.edu.co/index.php/inf_tec/article/view/3631</a> https://www.socictopen.socict.org/files/original/5ba44dff0212e132c39366563b92a674.pdf 1d54c6e8d608f10fc71fe26f362202f4 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Principales resultados en investigaciones del fitobentos marino cubano desde el CIM-UH (1970-2015)/ Main results in investigations of Cuban marine phytobenthos from the CIM-UH (1970-2015) Creator An entity primarily responsible for making the resource Beatriz Martínez-Daranas, Ana M. Suárez Description An account of the resource Se presentan los resultados fundamentales obtenidos en las investigaciones sobre el macrofitobentos de la plataforma marina cubana desde 1973, en el Centro de Investigaciones Marinas de la Universidad de La Habana. La mayoría se relaciona con los estudios de sistemática de macroalgas, con 159 nuevos reportes en el periodo. En ecología de fitobentos se ha trabajado en las nueve zonas de la plataforma. Se reflejan varios momentos en los estudios fitogeográficos de Cuba y zonas aledañas. También se presentan algunos de los resultados obtenidos sobre las características de las angiospermas marinas presentes en aguas cubanas y sobre el estado de conservación del ecosistema de pastos marinos, formado principalmente por Thalassia testudinum Banks ex König.AbstractThe key results of the research about the macrophytobenthos of the Cuban marine shelf since 1973, at the Center for Marine Research at the University of Havana, are presented. Most are related with systematics of macroalgae, with 159 new records in the period. Phytobenthos ecology has been worked in the nine zones of the marine shelf. Some phytogeographical studies in Cuba and adjacent zones are reflected. Some of the results on the characteristics of marine angiosperms in Cuban waters and the condition of the seagrass ecosystem, composed mainly Thalassia testudinum Banks ex König, are also presented. Date A point or period of time associated with an event in the lifecycle of the resource 2015 Subject The topic of the resource Cuba, HISTORIA, angiospermas, angiosperms, history, macroalgae, macroalgas, macrofitobentos, macrophytobenthos, pastos marinos, seagrass meadows Source A related resource from which the described resource is derived Revista de Investigaciones Marinas Publisher An entity responsible for making the resource available Universidad de La Habana Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Geography. Anthropology. Recreation, Oceanography Relation A related resource <a href="http://www.rim.uh.cu/index.php/RIM/article/view/273" target="_blank" rel="noreferrer noopener">http://www.rim.uh.cu/index.php/RIM/article/view/273</a> https://www.socictopen.socict.org/files/original/29fbb3d048cb01e566de3415d5e6bb4a.pdf a56af085276720b2491bb7c3ac6fb562 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Principios del derecho ambiental en el Acuerdo de París sobre Cambio Climático Creator An entity primarily responsible for making the resource Andrea Lucas Garín Description An account of the resource Este artículo se concentra en el último instrumento jurídico del régimen internacional de cambio climático, el Acuerdo de París, y en los principios ambientales que recoge. Se contextualiza con ese fin el fenómeno climático, su régimen propio y el largo camino que se ha seguido en las negociaciones climáticas para arribar a este acuerdo ambiental de última generación; luego se abordan los siete principios identificados como relevantes en el Acuerdo, así como otros temas de interés, para derivar algunas consecuencias que pueden generarse a la luz de este nuevo instrumento multilateral que está en proceso de implementación. Date A point or period of time associated with an event in the lifecycle of the resource 2019 Subject The topic of the resource Cambio climático, adaptación al cambio climático, derecho del medio ambiente;, principios ambientales, régimen internacional Identifier An unambiguous reference to the resource within a given context 10.18601/01229893.n44.08 Source A related resource from which the described resource is derived Revista Derecho del Estado Publisher An entity responsible for making the resource available Universidad Externado de Colombia Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Law in general. Comparative and uniform law. Jurisprudence Relation A related resource <a href="https://revistas.uexternado.edu.co/index.php/derest/article/view/6148" target="_blank" rel="noreferrer noopener">https://revistas.uexternado.edu.co/index.php/derest/article/view/6148</a> https://www.socictopen.socict.org/files/original/f4feb297e0842e696a4936ea6748c666.pdf 1a9d5c7c6a5bcdb1ce41989f607489f8 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Princípios ecológico-éticos da Sustentabilidade Socioambiental: o caso da Economia e da Agricultura Creator An entity primarily responsible for making the resource José Roque Junges Description An account of the resource A bioética ambiental, entendida como hermenêutica crítica, pode contribuir significativamente na discussão sobre as causas da crise ecológica e os parâmetros necessários para uma sustentabilidade socioambiental. Dois âmbitos da sociedade atual são centrais para essa questão: o modo como funciona a economia e a agricultura. A equação que rege o modelo de economia pelo consumo e que determina o tipo de agricultura pela química constituem processos produtivos que são ambientalmente suicidas, porque não respeitam os princípios básicos de funcionamento da natureza: ecocentrismo, entropia, trofobiose/homeostase. Por isso esses princípios precisam tornar-se parâmetros para definir e alcançar a sustentabilidade socioambiental. Date A point or period of time associated with an event in the lifecycle of the resource 2016 Subject The topic of the resource Agricultura ecológica, Bioética, Sustentabilidade ambiental, ecología, economía ecológica Identifier An unambiguous reference to the resource within a given context 10.14422/rib.i01.y2016.004 Source A related resource from which the described resource is derived Revista Iberoamericana de Bioética Publisher An entity responsible for making the resource available Universidad Pontificia Comillas Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medical philosophy. Medical ethics, Business ethics Relation A related resource <a href="http://revistas.upcomillas.es/index.php/bioetica-revista-iberoamericana/article/view/6767" target="_blank" rel="noreferrer noopener">http://revistas.upcomillas.es/index.php/bioetica-revista-iberoamericana/article/view/6767</a> https://www.socictopen.socict.org/files/original/8fc5e971d8bcf5812864b2fedfb2b0c4.pdf 248cada99f464c1c505121157d98a71b Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Principios ecológicos en la gestión de los agrosistemas Creator An entity primarily responsible for making the resource A. Bello, J. A. López-Pérez, M. A. Díez-Rojo, J. López-Cepero, A. García-Álvarez Description An account of the resource La agroecología tiene como objetivo el conocimiento de los elementos y procesos claves en el funcionamiento de los agrosistemas, para su eficaz gestión en armonía con el ambiente. La protección vegetal ha sido enfocada tradicionalmente, bajo el concepto de lucha y control, utilizando arsenales químicos o biológicos y, en estos momentos, biotecnológicos. La aplicación de criterios ecológicos en protección vegetal ha permitido desarrollar procesos como la biofumigación, fundamentada en la utilización de los gases resultantes de la biodescomposición de la materia orgánica para el manejo de organismos patógenos de los vegetales. Es de esperar que el futuro de la agricultura muestre una mayor preocupación por el ambiente, la conservación de los recursos naturales, la salud de las personas y se destaque su contribución a la reducción de la pobreza, así como su aportación al desarrollo de los agrocombustibles. Date A point or period of time associated with an event in the lifecycle of the resource 2008 Subject The topic of the resource agrocombustible, agroecologia, biofumigación, ecología del suelo, protección de cultivos Identifier An unambiguous reference to the resource within a given context 10.3989/arbor.2008.i729.158 Source A related resource from which the described resource is derived Arbor: Ciencia, Pensamiento y Cultura Publisher An entity responsible for making the resource available Consejo Superior de Investigaciones Científicas Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant General Works Relation A related resource <a href="http://arbor.revistas.csic.es/index.php/arbor/article/view/158" target="_blank" rel="noreferrer noopener">http://arbor.revistas.csic.es/index.php/arbor/article/view/158</a> https://www.socictopen.socict.org/files/original/edcb7f7d21be067bb65573205c862966.pdf a501b410629c2c23fe69a7def7ce9ddd Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Principios para un transporte urbano sostenible en Iberoamérica hacia la transición energética Creator An entity primarily responsible for making the resource Rodrigo Ramírez-Pisco, Carmen Luisa Vásquez Stanescu Description An account of the resource El presente trabajo tiene como propósito revelar los principios que, desde la transición energética, deben desarrollarse en Iberoamérica para garantizar el transporte urbano sostenible. En el mismo se encuentran incluidos los principios de movilidad presentados en diversos proyectos y acuerdos Europeos, con miras a disminuir los efectos del cambio climático producto de los vehículos de combustión. La  priorización de estos principios en función de la consulta a expertos realizada para la implementación en la región. Se priorizan de tres (3) grupos de principios que permitirán el desarrollo transporte urbano sostenible hacia la anhelada transición energética. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Cambio climático, Movilidad sostenible, sector transporte, transición energética, transporte urbano sostenible Identifier An unambiguous reference to the resource within a given context 10.24197/trim.17.2019.7-14 Source A related resource from which the described resource is derived Tordesillas, Revista de Investigación Multidisciplinar Publisher An entity responsible for making the resource available Universidad de Valladolid Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Social sciences (General), General Works, International relations Relation A related resource <a href="https://revistas.uva.es/index.php/trim/article/view/4195" target="_blank" rel="noreferrer noopener">https://revistas.uva.es/index.php/trim/article/view/4195</a> https://www.socictopen.socict.org/files/original/a15bd31a3d6b213e7bb20a2c44358674.pdf 0890acaeddfd1b78e4333bb83c8def0a Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Principles, Utility and Limitations of Pulse Oximetry in Management of COVID-19 Creator An entity primarily responsible for making the resource Lok Raj Joshi Description An account of the resource Pulse oximetry is an essential component of the standard care of COVID-19 patients. In the context of the spreading COVID-19 pandemic for which no targeted therapy or vaccines are yet available, early identification of the severe cases or cases with high risk of severe disease and appropriate supportive treatment are of paramount importance to save lives. Pulse oximetry is a cheap, fast, easy to use, noninvasive, painless and accurate tool that allows real-time monitoring of hypoxemia. As the primary target of the disease is the respiratory system pulse oximetry provides an unparalleled way to assess the severity of the disease, guide supportive therapies and monitor the clinical status and response to treatment with greater benefits in the low-resource settings. All settings from the quarantine facilities at the ground level to the ICUs in the highest level hospitals can utilize it to achieve their goals. To get the best of this tool, it needs to be used properly and the findings interpreted carefully. Role of basic understanding of the physiological principles and technology behind its use and awareness of its limitations cannot be overemphasized. The pulse oximetry readings are interpreted in the context of blood hemoglobin concentration, tissue perfusion, arterial blood carbon dioxide concentration and oxygen supplementation status. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource pulse oximetry, Nepal, Utility, limitations, COVID-19 Identifier An unambiguous reference to the resource within a given context DOI: 10.22502/jlmc.v8i1.356 Source A related resource from which the described resource is derived Journal of Lumbini Medical College Publisher An entity responsible for making the resource available Lumbini Medical College Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine (General) https://www.socictopen.socict.org/files/original/7ef366ea4de178677dd30d96469e6eeb.pdf aba12b4b1001809d8fce735ffcd22ee3 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Print Media Response to SARS in New Zealand Creator An entity primarily responsible for making the resource Nick Wilson, George Thomson, Osman Mansoor Description An account of the resource To examine the media response to severe acute respiratory syndrome, we reviewed New Zealand’s major newspaper (261 articles for 3 months). While important accurate health messages were frequently included, some were missed (e.g., handwashing in only 2% of articles). No incorrect information was identified, and health spokespersons were accurately reported. Date A point or period of time associated with an event in the lifecycle of the resource 2004 Subject The topic of the resource SARS virus, newspapers, Health promotion, Risk, risk reduction behaviour, communication Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid1008.031096 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/c4e1c3a3dc0b49833315a60668391175.pdf b15bd32067f7cb3604e9ff5f82ea832e Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Prior Routine Use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and Important Outcomes in Hospitalised Patients with COVID-19 Creator An entity primarily responsible for making the resource Eilidh Bruce, Fenella Barlow-Pay, Roxanna Short, Arturo Vilches-Moraga, Angeline Price, Aine McGovern, Philip Braude, Michael J. Stechman, Susan Moug, Kathryn McCarthy, Jonathan Hewitt, Ben Carter, Phyo Kyaw Myint Description An account of the resource Coronavirus disease 2019 (COVID-19) infection causes acute lung injury, resulting from aggressive inflammation initiated by viral replication. There has been much speculation about the potential role of non-steroidal inflammatory drugs (NSAIDs), which increase the expression of angiotensin-converting enzyme 2 (ACE2), a binding target for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to enter the host cell, which could lead to poorer outcomes in COVID-19 disease. The aim of this study was to examine the association between routine use of NSAIDs and outcomes in hospitalised patients with COVID-19. This was a multicentre, observational study, with data collected from adult patients with COVID-19 admitted to eight UK hospitals. Of 1222 patients eligible to be included, 54 (4.4%) were routinely prescribed NSAIDs prior to admission. Univariate results suggested a modest protective effect from the use of NSAIDs, but in the multivariable analysis, there was no association between prior NSAID use and time to mortality (adjusted HR (aHR) = 0.89, 95% CI 0.52–1.53, p = 0.67) or length of stay (aHR 0.89, 95% CI 0.59–1.35, p = 0.58). This study found no evidence that routine NSAID use was associated with higher COVID-19 mortality in hospitalised patients; therefore, patients should be advised to continue taking these medications until further evidence emerges. Our findings suggest that NSAID use might confer a modest benefit with regard to survival. However, as this finding was underpowered, further research is required. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, SARS-CoV-2, non-steroidal anti-inflammatory drugs, NSAIDs Identifier An unambiguous reference to the resource within a given context 10.3390/jcm9082586 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine https://www.socictopen.socict.org/files/original/c3db8c50e7f6d97c2f8e31075ef9f023.pdf e74a95caff8e4b1f8b76653398d2b0ea Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose. Creator An entity primarily responsible for making the resource Mala K Maini, Catherine J Reynolds, Joseph M Gibbons, Corinna Pade, David K Butler, Teresa Cutino-Moguel, Marianna Fontana, Angelique Smit, Amanda Semper, Benjamin Chain, Tim Brooks, Charlotte Manisty, Thomas Treibel, James C Moon, Mahdad Noursadeghi, Daniel M Altmann, Áine McKnight, Rosemary J Boyton, Ashley D Otter, Katia Menacho, Jane E Sackville-West, Ana M Valdes Description An account of the resource SARS-CoV-2 vaccine rollout has coincided with the spread of variants of concern. We investigated if single dose vaccination, with or without prior infection, confers cross protective immunity to variants. We analyzed T and B cell responses after first dose vaccination with the Pfizer/BioNTech mRNA vaccine BNT162b2 in healthcare workers (HCW) followed longitudinally, with or without prior Wuhan-Hu-1 SARS-CoV-2 infection. After one dose, individuals with prior infection showed enhanced T cell immunity, antibody secreting memory B cell response to spike and neutralizing antibodies effective against B.1.1.7 and B.1.351. By comparison, HCW receiving one vaccine dose without prior infection showed reduced immunity against variants. B.1.1.7 and B.1.351 spike mutations resulted in increased, abrogated or unchanged T cell responses depending on human leukocyte antigen (HLA) polymorphisms. Single dose vaccination with BNT162b2 in the context of prior infection with a heterologous variant substantially enhances neutralizing antibody responses against variants. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Identifier An unambiguous reference to the resource within a given context 10.1126/science.abh1282 Source A related resource from which the described resource is derived Science (New York, N.Y.)