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                <text>Pengfei Niu, Fuming Lei, Jin Gu</text>
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                <text>Pains and Gains from China’s Experiences with Emerging Epidemics: From SARS to H7N9</text>
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                <text>Pengfei Wei, Zelang Cai, Jinwen Hua, Weijia Yu, Jiajie Chen, Kang Kang, Congling Qiu, Lanlan Ye, Jiayun Hu, Kunmei Ji</text>
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                <text>Over the recent decades, China experienced several emerging virus outbreaks including those caused by the severe acute respiratory syndrome- (SARS-) coronavirus (Cov), H5N1 virus, and H7N9 virus. The SARS tragedy revealed faults in China’s infectious disease prevention system, propelling the Chinese government to enact reforms that enabled better combating of the subsequent H1N1 and H7N9 avian flu epidemics. The system is buttressed by three fundamental, mutually reinforcing components: (1) enduring government administration reforms, including legislation establishing a unified public health emergency management system; (2) prioritized funding for biotechnology and biomedicine industrialization, especially in the areas of pathogen identification, drug production, and the development of vaccines and diagnostics; and (3) increasing investment for public health and establishment of a rapid-response infectious diseases prevention and control system. China is now using its hard-gained experience to support the fight against Ebola in Africa and the Middle East Respiratory Syndrome in its own country.</text>
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                <text>DOI: 10.1155/2016/5717108</text>
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                <text>BioMed Research International</text>
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                <text>Successes and challenges of the One Health approach in Kenya over the last decade</text>
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                <text>Peninah M. Munyua, M. Kariuki Njenga, Eric M. Osoro, Clayton O. Onyango, Austine O. Bitek, Athman Mwatondo, Mathew K. Muturi, Norah Musee, Godfrey Bigogo, Elkanah Otiang, Fredrick Ade, Sara A. Lowther, Robert F. Breiman, John Neatherlin, Joel Montgomery, Marc-Alain Widdowson</text>
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                <text>Abstract More than 75% of emerging infectious diseases are zoonotic in origin and a transdisciplinary, multi-sectoral One Health approach is a key strategy for their effective prevention and control. In 2004, US Centers for Disease Control and Prevention office in Kenya (CDC Kenya) established the Global Disease Detection Division of which one core component was to support, with other partners, the One Health approach to public health science. After catalytic events such as the global expansion of highly pathogenic H5N1 and the 2006 East African multi-country outbreaks of Rift Valley Fever, CDC Kenya supported key Kenya government institutions including the Ministry of Health and the Ministry of Agriculture, Livestock, and Fisheries to establish a framework for multi-sectoral collaboration at national and county level and a coordination office referred to as the Zoonotic Disease Unit (ZDU). The ZDU has provided Kenya with an institutional framework to highlight the public health importance of endemic and epidemic zoonoses including RVF, rabies, brucellosis, Middle East Respiratory Syndrome Coronavirus, anthrax and other emerging issues such as anti-microbial resistance through capacity building programs, surveillance, workforce development, research, coordinated investigation and outbreak response. This has led to improved outbreak response, and generated data (including discovery of new pathogens) that has informed disease control programs to reduce burden of and enhance preparedness for endemic and epidemic zoonotic diseases, thereby enhancing global health security. Since 2014, the Global Health Security Agenda implemented through CDC Kenya and other partners in the country has provided additional impetus to maintain this effort and Kenya’s achievement now serves as a model for other countries in the region. Significant gaps remain in implementation of the One Health approach at subnational administrative levels; there are sustainability concerns, competing priorities and funding deficiencies.</text>
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                <text>2019</text>
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                <text>zoonosis, Cross-sectoral collaboration global health security</text>
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                <text>DOI: 10.1186/s12889-019-6772-7</text>
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                <text>BMC Public Health</text>
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                <text>Public aspects of medicine</text>
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                <text>EN</text>
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                <text>Should Autism Spectrum Conditions Be Characterised in a More Positive Way in Our Modern World?</text>
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                <text>Penny Spikins, Barry Wright, Hannah Pearson</text>
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                <text>In a special issue that focuses on complex presentations related to Autism, we ask the question in this editorial whether an Autism Spectrum Condition without complexity is a disorder, or whether it represents human diversity? Much research into Autism Spectrum Conditions (ASCs) over the years has focused on comparisons between neuro-typical people and people with Autism Spectrum Conditions. These comparisons have tended to draw attention to ‘deficits’ in cognitive abilities and descriptions of behaviours that are characterised as unwanted. Not surprisingly, this is reflected in the classification systems from the World Health Organisation and the American Psychiatric Association. Public opinion about ASC may be influenced by presentations in the media of those with ASC who also have intellectual disability. Given that diagnostic systems are intended to help us better understand conditions in order to seek improved outcomes, we propose a more constructive approach to descriptions that uses more positive language, and balances descriptions of deficits with research finding of strengths and differences. We propose that this will be more helpful to individuals on the Autism Spectrum, both in terms of individual self-view, but also in terms of how society views Autism Spectrum Conditions more positively. Commentary has also been made on guidance that has been adjusted for people with ASC in relation to the current COVID-19 pandemic.</text>
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                <text>2020</text>
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                <text>autism, Diagnostic criteria, positive, strengths, COVID-19, autism spectrum condition (ASC)</text>
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                <text>DOI: 10.3390/medicina56050233</text>
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                <text>Medicine (General)</text>
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                <text>A Spatial-Temporal Model for the Evolution of the COVID-19 Pandemic in Spain Including Mobility</text>
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                <text>Pep Mulet, Francesc Aràndiga, Antonio Baeza, Isabel Cordero-Carrión, Rosa Donat, M.  Carmen Martí, Dionisio  F. Yáñez</text>
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                <text>In this work, a model for the simulation of infectious disease outbreaks including mobility data is presented. The model is based on the SAIR compartmental model and includes mobility data terms that model the flow of people between different regions. The aim of the model is to analyze the influence of mobility on the evolution of a disease after a lockdown period and to study the appearance of small epidemic outbreaks due to the so-called imported cases. We apply the model to the simulation of the COVID-19 in the various areas of Spain, for which the authorities made available mobility data based on the position of cell phones. We also introduce a method for the estimation of incomplete mobility data. Some numerical experiments show the importance of data completion and indicate that the model is able to qualitatively simulate the spread tendencies of small outbreaks. This work was motivated by an open call made to the mathematical community in Spain to help predict the spread of the epidemic.</text>
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                <text>Per P. Bredmose, Monica Diczbalis, Emma Butterfield, Karel Habig, Andrew Pearce, Svein Are Osbakk, Ville Voipio, Marcus Rudolph, Alistair Maddock, John O’Neill</text>
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                <text>Abstract The novel coronavirus SARS-CoV2 emerged in December 2019 and is now pandemic. Initial analysis suggests that 5% of infected patients will require critical care, and that respiratory failure requiring intubation is associated with high mortality. Sick patients are geographically dispersed: most patients will remain in situ until they are in need of critical care. Additionally, there are likely to be patients who require retrieval for other reasons but who are co-incidentally infected with SARS-CoV-2 or shedding virus. The COVID-19 pandemic therefore poses a challenge to critical care retrieval systems, which often depend on small teams of specialists who live and work together closely. The infection or quarantining of a small absolute number of these staff could catastrophically compromise service delivery. Avoiding occupational exposure to COVID-19, and thereby ensuring service continuity, is the primary objective of aeromedical retrieval services during the pandemic. In this discussion paper we collaborated with helicopter emergency medical services(HEMS) worldwide to identify risks in retrieving COVID-19 patients, and develop strategies to mitigate these. Simulation involving the whole aeromedical retrieval team ensures that safety concerns can be addressed during the development of a standard operating procedure. Some services tested personal protective equipment and protocols in the aeromedical environment with simulation. We also incorporated experiences, standard operating procedures and approaches across several HEMS services internationally. As a result of this collaboration, we outline an approach to the safe aeromedical retrieval of a COVID-19 patient, and describe how this framework can be used to develop a local standard operating procedure.</text>
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                <text>Universidade Federal de Santa Catarina</text>
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                <text>Recensió bibliogràfica de  Do Couto, Hildo H.; Nakayama Nonoki do Couto, Elza K.; de Araújo, Gilberto P.; Borges de Albuquerque, Davi (org.). (2016). «O paradigma ecológico para as ciências da linguagem: ensaios ecolinguísticos clássicos e contemporâneos»</text>
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                <text>Romanic languages, Language and Literature</text>
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                <text>&lt;a href="http://revistes.eapc.gencat.cat/index.php/rld/article/view/2839" target="_blank" rel="noreferrer noopener"&gt;http://revistes.eapc.gencat.cat/index.php/rld/article/view/2839&lt;/a&gt;</text>
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                <text>Perla Yannelli Fernández Silva, David Morillón Gálvez</text>
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                <text>La importancia de incrementar el número de viviendas sustentables, y con ello contribuir a frenar los efectos del cambio climático, responde a que 4.62% de las emisiones de CO2 provienen del sector habitacional. Las ecotecnologías para la vivienda son dispositivos con potencial para reducir emisiones de gases de efecto invernadero, así como para ahorrar. Estos instrumentos están cada vez más disponibles en el mercado, sin que se utilicen de manera generalizada en las viviendas de la Ciudad de México. Este trabajo identifica las diferencias entre la población que conoce y utiliza ecotecnias en las viviendas de la capital mexicana. Por medio de encuestas y estadísticas se encontraron diferencias significativas entre cinco estratos socioterritoriales en las formas de conocimiento y uso de ecotecnologías para la vivienda.</text>
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                <text>Ciudad de México, análisis socio, construccionismo social, ecotecnologías para la vivienda, territorial</text>
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                <text>Estudios Demográficos y Urbanos</text>
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                <text>El Colegio de México, A.C.</text>
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                <text>Human settlements. Communities, Demography. Population. Vital events</text>
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                <text>Amelia L Persico, 1, 2 Erica L Wegrzyn, 1, 2 Jeffrey Fudin, 1, 2 Michael E Schatman 3, 4  1Stratton VA Medical Center, Albany, NY, USA;  2Remitigate Therapeutics, Delmar, NY, USA;  3Tufts University School of Dental Medicine, Boston, MA, USA;  4Tufts University School of Medicine, Boston, MA, USACorrespondence: Jeffrey Fudin Email jeff@paindr.com The ongoing media maelstrom regarding opioids and classification of an &amp;ldquo;opioid&amp;nbsp;crisis&amp;rdquo; during the initial decade of this millennium has stirred awareness, outrage&amp;nbsp;and action among regulatory and other&amp;nbsp; government agencies, professional clinician&amp;nbsp;organizations, community pharmacy policies, legislators, patient advocacy groups,&amp;nbsp;anti-opioid advocate groups, and others. However, mass media reports often skew&amp;nbsp;or misdirect the aggregate facts in a possible effort to abridge or sensationalize&amp;nbsp;stories.1 Discernable distinctions, for example, are rarely drawn between licit&amp;nbsp;pharmaceutical fentanyl, illicit fentanyl analogues, and certain highly potent&amp;nbsp;analogues approved only for ungulates. The omission of this information has&amp;nbsp;resulted in distorted public information that has far reaching consequences in&amp;nbsp;medicine and policy development, as it leads to misunderstanding and misinterpretation&amp;nbsp;of the facts by politicians, lay people and many clinicians.2 It is particularly&amp;nbsp;relevant today, as pharmaceutical fentanyl is often an essential drug for intubationregularly required for ventilation procedures in declining patients that may succumb&amp;nbsp;to novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). These&amp;nbsp;distinctions are critical in the shifting landscape of the opioid crisis as prescriptions&amp;nbsp;for opioids decrease yet overdose deaths remain alarmingly prevalent and continue&amp;nbsp;to rise. &amp;nbsp; &amp;nbsp;</text>
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                <text>Biotemas</text>
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                <text>Universidade Federal de Santa Catarina</text>
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        <src>https://www.socictopen.socict.org/files/original/0ca7af5391e3f397c7e37ae442c32803.pdf</src>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                <elementText elementTextId="1">
                  <text>Coronavirus</text>
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              </elementTextContainer>
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            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Prediction of Single Point Mutations in Human Coronavirus and Their Effects on Binding to 9-O-Acetylated Sialic Acid and Hidroxychloroquine</text>
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            <name>Creator</name>
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              <elementText elementTextId="65240">
                <text>Petar M Mitrasinovic</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>Due to the current spreading of the new disease CoViD-19, the World Health Organization formally declared a world pandemic on March 11, 2020. The present trends indicate that the pandemic will have an enormous clinical and economic impact on population health. Infections are initiated by the transmembrane spike (S) glycoproteins of human coronavirus (hCoV) binding to host receptors. Ongoing research and therapeutic product development are of vital importance for the successful treatment of CoViD-19. To contribute somewhat to the overall effort, herein, single point mutations (SPMs) of the binding site residues in hCoV-OC43 S that recognizes cellular surface components containing 9-O-acetylated sialic acid (9-O-Ac-Sia) are explored using an in silico protein engineering approach, while their effects on the binding of 9-O-Ac-Sia and Hidroxychloroquine (Hcq) are evaluated using molecular docking simulations. Thr31Met and Val84Arg are predicted to be the critical – most likely SPMs in hCoV-OC43 S for the binding of 9-O-Ac-Sia and Hcq, respectively, even though Thr31Met is a very likely SPM in the case of Hcq too. The corresponding modes of interaction indicate a comparable strength of the Thr31Met/9-O-Ac-Sia and Val84Arg/Hcq (or Thr31Met/Hcq) complexes. Given that the binding site is conserved in all CoV S glycoproteins that associate with 9-O-acetyl-sialoglycans, the high hydrophobic affinity of Hcq to hCoV-OC43 S speaks in favor of its ability to competitively inhibit rapid S-mediated virion attachment in high-density receptor environments, but its considerably low specificity to hCoV-OC43 S may be one of the key obstacles in considering the potential of Hcq to become a drug candidate.</text>
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            <name>Date</name>
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                <text>2020</text>
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          <element elementId="49">
            <name>Subject</name>
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                <text>coronavirus, covid-19, Pandemic, single-point-mutation, hidroxychloroquine</text>
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            <name>Identifier</name>
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              <elementText elementTextId="65244">
                <text>10.17344/acsi.2020.6009</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="65245">
                <text>Acta Chimica Slovenica</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="65246">
                <text>Slovenian Chemical Society</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="65247">
                <text>Chemistry</text>
              </elementText>
            </elementTextContainer>
          </element>
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  </item>
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