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                <text>Health care systems worldwide have been facing major challenges since the outbreak of the SARS-CoV-2 pandemic. Kidney transplantation (KT) has been tremendously affected due to limited personal protective equipment (PPE) and intensive care unit (ICU) capacities. To provide valid information on risk factors for ICU admission in a high-risk cohort of old kidney recipients from old donors in the Eurotransplant Senior Program (ESP), we retrospectively conducted a bi-centric analysis. Overall, 17 (16.2%) patients out of 105 KTs were admitted to the ICU. They had a lower BMI, and both coronary artery disease (CAD) and hypertensive nephropathy were more frequent. A risk model combining BMI, CAD and hypertensive nephropathy gained a sensitivity of 94.1% and a negative predictive value of 97.8%, rendering it a valuable search test, but with low specificity (51.1%). ICU admission also proved to be an excellent parameter identifying patients at risk for short patient and graft survivals. Patients admitted to the ICU had shorter patient (1-year 57% vs. 90%) and graft (5-year 49% vs. 77%) survival. To conclude, potential kidney recipients with a low BMI, CAD and hypertensive nephropathy should only be transplanted in the ESP in times of SARS-CoV-2 pandemic if the local health situation can provide sufficient ICU capacities.</text>
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                <text>Epidemiology and Health</text>
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                <text>Philipp A Reuken, Andreas Stallmach, Mathias W Pletz, Christian Brandt, Nico Andreas, Sabine Hahnfeld, Bettina Löffler, Sabine Baumgart, Thomas Kamradt, Michael Bauer</text>
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                <text>The research aims to explore ways of improving adaptability of international first-year university students based on the experience of making the transition from face-to-face learning to various online platforms during the nationwide pandemic lockdown in Russia in spring 2020. The research purpose is to analyze various sociocultural, technical and other challenges faced by international students after the one-day seamless transition to remote learning and their impact on the attendance record, motivation, academic performance and other quantitative and qualitative data. The research topic relevance is determined by the substantial rise in popularity of online learning, which had been demonstrating exponential growth even prior to the events of 2020, which further accelerated its expansion. The research methods integrate theoretical analysis of the current trends in online learning and its evolution as well as the strengths, weaknesses, threats and opportunities analysis. Statistical data was collected and processed using the University's digital ecosystem. The research data includes the results of the survey consisting of multiple-choice, single-choice and open-end questions, interviews with the students as well as the faculty and the background material. The research sample includes international first-year students from 12 countries with CEFR levels of the Russian language proficiency ranging from A1 to B1. The research findings show that the speed of adaptation to online learning depends on various psychological and technological factors as well as the students’ learning abilities. The findings lead to the conclusion that despite the efforts of the faculty to make this process a seamless one, some factors lie beyond its reach, which makes neutralizing the disadvantages of remote teaching time-consuming. The research results demonstrate the potential ways of improving online learning for all parties concerned by implementing such features as risk management plans, knowledge bases, focusing on making the content user-friendly and introducing other various quality-of-life improvements.</text>
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                <text>La  adaptación  al  cambio  climático  ha  ido  cobrando  importancia  desde  comienzos  del  siglo  actual.   Históricamente la adaptación, no al cambio climático sino a los eventos atmosféricos extremos, estaba  profundamente arraigada en muchas sociedades y en su forma de ocupar el territorio. Con la industria - lización y especialmente con el aumento de la globalización desde los años noventa del pasado siglo, la  importancia de una adecuada adaptación al territorio ha ido perdiendo protagonismo, lo que ha aumenta - do la exposición y el riesgo de los asentamientos humanos en áreas potencialmente afectadas por los im - pactos del cambio climático (p.e. subida del nivel de mar) y/o por eventos extremos (peligros naturales).  Para desarrollar medidas de adaptación al cambio climático es necesario identificar soluciones viables, es  decir, viables y aceptables desde el punto de vista socioeconómico. La identificación de estas soluciones  factibles va más allá del análisis científico puro puesto que incorpora a todas las partes interesadas, inclui - dos los responsables en la toma de decisiones y el propio conocimiento local.</text>
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