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                  <text>Dominio científico: Coronavirus</text>
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                <text>Remote Design and Manufacture through the Example of a Ventilator</text>
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                <text>Marek Bolanowski, Piotr Sowa, Mariusz Oleksy, Grzegorz BUDZIK, Andrzej Paszkiewicz, Tomasz Pisz, Łukasz Przeszłowski</text>
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                <text>In this paper, the authors present a completely new approach to the remote prototyping process, taking into account the distributed nature of design and manufacturing resources. A new model is suggested, taking into account the conditions of the Industry 4.0 concept, along with a component of remote implementation and coordination of operations. On the basis of this model, the architecture of the target system is developed, which is further built and implemented in the actual productive environment. The system’s functionality additionally enables the implementation of the design and production process in critical conditions resulting from natural disasters or epidemic states. The practical application of the developed solutions is presented on the design of a ventilator, which is dedicated to help in the fight against epidemic states, e.g., coronavirus.</text>
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                <text>3D printing, rapid prototyping, cloud computing, Industry 4.0, COMPUTER NETWORKS, computer systems</text>
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                <text>DOI: 10.3390/app10124235</text>
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                <text>Biology (General), Technology, Physics, Chemistry, Engineering (General). Civil engineering (General)</text>
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                <text>The COVID-19 Diagnostic Technology Landscape: Efficient Data Sharing Drives Diagnostic Development</text>
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                <text>Luis G. C. Pacheco, Jesús Navas, Eric R. G. R. Aguiar</text>
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                <text>DOI: 10.3389/fpubh.2020.00309</text>
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                <text>Frontiers in Public Health</text>
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                <text>Frontiers Media S.A.</text>
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                <text>Public aspects of medicine</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Spread and Impact of COVID-19 in China: A Systematic Review and Synthesis of Predictions From Transmission-Dynamic Models</text>
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                <text>Zhenyu Wang, Yifan Lin, Peiyang Li, Yong Lü, He-Ping Zhao, Dahui Chen, Song Fan, Xiaoting Chen, Meijuan Li, Yuelong Shu, Huachun Zou, Bowen Liang, Weiping Cai, Bing-yi WANG, Linghua Li, Ganfeng Luo, Thomas Fitzpatrick, Yiguo Zhou, Qibin Duan, Tanwei Yuan, Xiangjun Du, Yuewei Zhan, Leiwen Fu, Yunlong Ao, Anping Feng, Yanxiao Gao</text>
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                <text>Background: Coronavirus disease 2019 (COVID-19) was first identified in Wuhan, China, in December 2019 and quickly spread throughout China and the rest of the world. Many mathematical models have been developed to understand and predict the infectiousness of COVID-19. We aim to summarize these models to inform efforts to manage the current outbreak.Methods: We searched PubMed, Web of science, EMBASE, bioRxiv, medRxiv, arXiv, Preprints, and National Knowledge Infrastructure (Chinese database) for relevant studies published between 1 December 2019 and 21 February 2020. References were screened for additional publications. Crucial indicators were extracted and analysed. We also built a mathematical model for the evolution of the epidemic in Wuhan that synthesised extracted indicators.Results: Fifty-two articles involving 75 mathematical or statistical models were included in our systematic review. The overall median basic reproduction number (R0) was 3.77 [interquartile range (IQR) 2.78–5.13], which dropped to a controlled reproduction number (Rc) of 1.88 (IQR 1.41–2.24) after city lockdown. The median incubation and infectious periods were 5.90 (IQR 4.78–6.25) and 9.94 (IQR 3.93–13.50) days, respectively. The median case-fatality rate (CFR) was 2.9% (IQR 2.3–5.4%). Our mathematical model showed that, in Wuhan, the peak time of infection is likely to be March 2020 with a median size of 98,333 infected cases (range 55,225–188,284). The earliest elimination of ongoing transmission is likely to be achieved around 7 May 2020.Conclusions: Our analysis found a sustained Rc and prolonged incubation/ infectious periods, suggesting COVID-19 is highly infectious. Although interventions in China have been effective in controlling secondary transmission, sustained global efforts are needed to contain an emerging pandemic. Alternative interventions can be explored using modelling studies to better inform policymaking as the outbreak continues.</text>
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                <text>mathematical model, incubation, Fatality, the reproduction number, Infectious period</text>
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                <text>DOI: 10.3389/fmed.2020.00321</text>
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                <text>Frontiers in Medicine</text>
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                <text>Frontiers Media S.A.</text>
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                <text>Medicine (General)</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Potential of SARS-CoV-2 to Cause CNS Infection: Biologic Fundamental and Clinical Experience</text>
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                <text>Xin Tang, Liangxue Zhou, Aiping Tong, Jianhan Huang, Meijun Zheng, Yaxing Chen</text>
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                <text>SARS-CoV-2 is a novel coronavirus leading to serious respiratory disease and is spreading around the world at a raging speed. Recently there is emerging speculations that the central nervous system (CNS) may be involved during SARS-CoV-2 infection, contributing to the respiratory failure. However, the existence of viral replication in CNS has not been confirmed due to the lack of evidence from autopsy specimens. Considering the tropism of SARS-CoV-2, ACE2, is prevailing in CNS, and the neuro-invasive property of human coronavirus was widely reported, there is a need to identified the possible complications during COVID-19 for CNS. In this review, we conduct a detailed summary for the potential of SARS-CoV-2 to infect central nervous system from latest biological fundamental of SARS-CoV-2 to the clinical experience of other human coronaviruses. To confirm the neuro-invasive property of SARS-CoV-2 and the subsequent influence on patients will require further exploration by both virologist and neurologist.</text>
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                <text>central nervous system, Viral infection, human coronavirus, SARS-CoV-2, COVID-19</text>
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                <text>DOI: 10.3389/fneur.2020.00659</text>
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                <text>Frontiers in Neurology</text>
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                <text>Frontiers Media S.A.</text>
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                <text>Neurology. Diseases of the nervous system</text>
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                <text>Does Longer Leukocyte Telomere Length and Higher Physical Fitness Protect Master Athletes From Consequences of Coronavirus (SARS-CoV-2) Infection?</text>
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                <text>Carmen Sílvia Grubert Campbell, Herbert Gustavo Simões, Hans Degens, Daisy Motta-Santos, Samuel da Silva Aguiar, Marko T. Korhonen, Caio Victor Sousa, Thiago Santos Rosa</text>
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                <text>We Are Not Alone in Trying to Be Alone</text>
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                <text>DOI: 10.3389/fevo.2020.00172</text>
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                <text>Frontiers in Ecology and Evolution</text>
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                <text>Ecology, Evolution</text>
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                <text>COVID-19 Is Further Subdivided Into COVIP-19 and COVII-19</text>
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                <text>Shiliang Song</text>
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              <elementText elementTextId="37473">
                <text>DOI: 10.3389/fpubh.2020.00301</text>
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                <text>Frontiers in Public Health</text>
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              <elementText elementTextId="37475">
                <text>Frontiers Media S.A.</text>
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                <text>Public aspects of medicine</text>
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                  <text>Dominio científico: Coronavirus</text>
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          <element elementId="50">
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                <text>Covid-19 and spatial planning</text>
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              <elementText elementTextId="37461">
                <text>Federica Leone, Corrado Zoppi, Sabrina Lai</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>This article analyzes some relevant questions as regards the impact of COVID-19-related social living conditions on spatial planning policies and practices. The proposed discussion aims at highlighting and discussing a number of outstanding topics of spatial planning which public administrative bodies, practitioners, entrepreneurs and organizations operating in the profit and non-profit sectors, and the local communities should carefully consider with reference to a new planning outset after the lockdown period. Innovative and creative approaches should be identified and implemented when dealing with collective public spaces, shopping malls, retail activities and related areas, urban and regional mobility-related infrastructure and services, food-supply changes and their implications in terms of development of local food-producing practices, spatial social control and privacy, mitigation of climate change-related negative impacts, and public awareness and commitment towards losers, especially urban losers. Each of these points presents important challenges for the future of spatial planning. Some of these challenges are synthetically described and discussed in this article.</text>
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            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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              <elementText elementTextId="37463">
                <text>2020</text>
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            <description>The topic of the resource</description>
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              <elementText elementTextId="37464">
                <text>climate change, mobility, food self-sufficiency, COVID-19, post-lockdown planning</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="37465">
                <text>DOI: 10.6092/1970-9870/6846</text>
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              <elementText elementTextId="37466">
                <text>TeMA: Journal of Land Use, Mobility and Environment</text>
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              <elementText elementTextId="37467">
                <text>Università di Napoli Federico II</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="37468">
                <text>Transportation engineering, Urbanization. City and country</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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          <element elementId="50">
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                <text>Passata è la tempesta …”. A land use planning vision for the Italian Mezzogiorno in the post pandemic"</text>
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                <text>Paolo La Greca, Francesco Martinico, Fausto Carmelo Nigrelli</text>
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                <text>The Covid-19 pandemic event can activate a comprehensive reflection on the change of development models, overcoming the current unsustainable ones. Present events in Italy are mainly affecting Northern Regions but also the Southern ones will suffer from economic consequences, related to the pandemic. This is particularly relevant for the marginal areas of the Italian Mezzogiorno. The article highlights issues that are deemed relevant for including inner areas of Italian Southern regions into the process of economic recovery after the pandemic, in order to avoid the deepening of the long lasting North South imbalance, in the light of the growing depopulation of this part of the Country. The focus is on the role of Health Services, Education, Built up Environment and Transports, systems considered as key elements for promoting a well-balanced use of existing territorial assets. The real challenge is to reverse this terrible threat into an opportunity, introducing effective changes into the way we waste our limited planetary resources, especially the territorial ones. In this direction, Southern regions can play a fundamental role for increasing the resilience of the entire nation.</text>
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                <text>2020</text>
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                <text>regional development, regional planning, Italian Mezzogiorno</text>
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                <text>DOI: 10.6092/1970-9870/6853</text>
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                <text>Università di Napoli Federico II</text>
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                <text>Transportation engineering, Urbanization. City and country</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>The resilient city and adapting to the health emergency</text>
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                <text>Francesca Pirlone, Ilenia Spadaro</text>
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                <text>The concept of a resilient city is an increasingly critical one. Resilience represents the ability of an urban system to adapt to an external event. In the past, urban resilience was mainly addressed to natural rather than anthropic risks. Considering the Covid-19 pandemic emergency, the relationship between urban resilience and anthropic risk, especially health risk, has inevitably distorted the “normality” to which we were accustomed. The emergency has had significant long-term effects on the times, uses and organization of cities. Adaptability requires the synergic work of all actors who live or work in a city. This mobility-focused research aims to highlight the importance of the Quadruple Helix principle by analysing the specific measures that each actor -Public Authorities, Research, Enterprises and Citizens- can implement to reduce health risk. The paper outlines the contribution of the University of Genoa within the confines of a ministerial project to promote sustainable mobility for students, when travelling between home and university, using prizes/incentives. This good practice will play an increasingly important role in the return to normality.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="37445">
                <text>2020</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="37446">
                <text>Resilience, quadruple helix principle, university students’ sustainable mobility</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="37447">
                <text>DOI: 10.6092/1970-9870/6856</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="37448">
                <text>TeMA: Journal of Land Use, Mobility and Environment</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="37449">
                <text>Università di Napoli Federico II</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="37450">
                <text>Transportation engineering, Urbanization. City and country</text>
              </elementText>
            </elementTextContainer>
          </element>
        </elementContainer>
      </elementSet>
    </elementSetContainer>
  </item>
</itemContainer>
