1714 10 20655 https://www.socictopen.socict.org/files/original/da25b33827569a02417324e21f370583.pdf 063ebddd646af0c10405470602d9404c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource SARS-CoV-2 and Coronavirus Disease 2019: What We Know So Far Creator An entity primarily responsible for making the resource Firas A. Rabi, Mazhar S. Al Zoubi, Ghena A. Kasasbeh, Dunia M. Salameh, Amjad D. Al-Nasser Description An account of the resource In December 2019, a cluster of fatal pneumonia cases presented in Wuhan, China. They were caused by a previously unknown coronavirus. All patients had been associated with the Wuhan Wholefood market, where seafood and live animals are sold. The virus spread rapidly and public health authorities in China initiated a containment effort. However, by that time, travelers had carried the virus to many countries, sparking memories of the previous coronavirus epidemics, severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), and causing widespread media attention and panic. Based on clinical criteria and available serological and molecular information, the new disease was called coronavirus disease of 2019 (COVID-19), and the novel coronavirus was called SARS Coronavirus-2 (SARS-CoV-2), emphasizing its close relationship to the 2002 SARS virus (SARS-CoV). The scientific community raced to uncover the origin of the virus, understand the pathogenesis of the disease, develop treatment options, define the risk factors, and work on vaccine development. Here we present a summary of current knowledge regarding the novel coronavirus and the disease it causes. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource coronavirus, COVID-19, SARS, SARS-CoV-2, Wuhan, Pandemic Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/pathogens9030231 Source A related resource from which the described resource is derived Pathogens Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/d1256a028b55e427c067146ade4ba9b9.pdf 24ce7d102f772f64ac645c19aa0d159a Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource SARS-CoV-2 and COVID-19: The most important research questions Creator An entity primarily responsible for making the resource Kit-San Yuen, Zi-Wei Ye, Sin-Yee Fung, Chi-Ping Chan, Dong-Yan Jin Description An account of the resource Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an ongoing global health emergency. Here we highlight nine most important research questions concerning virus transmission, asymptomatic and presymptomatic virus shedding, diagnosis, treatment, vaccine development, origin of virus and viral pathogenesis. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource SARS-CoV-2, COVID-19, 2019 novel coronavirus (2019-nCoV), Novel coronavirus pneumonia (NCP) Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/s13578-020-00404-4 Source A related resource from which the described resource is derived Cell & Bioscience Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General), Biochemistry, Biotechnology Language A language of the resource EN https://www.socictopen.socict.org/files/original/789b0dd51ccd1eaf78edecc896191095.pdf 9c446eb19ea356c3aaf85352bad839e8 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource SARS-CoV-2 and endothelial cell interaction in COVID-19: molecular perspectives Creator An entity primarily responsible for making the resource Roberta Giordo, Panagiotis Paliogiannis, Arduino Aleksander Mangoni, Gianfranco Pintus Description An account of the resource SARS-CoV-2 is the agent responsible for the coronavirus disease (COVID-19), which has been declared a pandemic by the World Health Organization. The clinical evolution of COVID-19 ranges from asymptomatic infection to death. Older people and patients with underlying medical conditions, particularly diabetes, cardiovascular and chronic respiratory diseases are more susceptible to develop severe forms of COVID-19. Significant endothelial damage has been reported in COVID-19 and growing evidence supports the key pathophysiological role of this alteration in the onset and the progression of the disease. In particular, the impaired vascular homeostasis secondary to the structural and functional damage of the endothelium and its main component, the endothelial cells, contributes to the systemic proinflammatory state and the multiorgan involvement observed in COVID-19 patients. This review summarizes the current evidence supporting the proposition that the endothelium is a key target of SARS-CoV-2, with a focus on the molecular mechanisms involved in the interaction between SARS-CoV-2 and endothelial cells. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource covid-19, SARS-CoV-2, ACE2, cardiovascular disease, endothelial cell, endothelial damage Identifier An unambiguous reference to the resource within a given context https://doi.org/10.1530/VB-20-0017 Source A related resource from which the described resource is derived Vascular Biology Publisher An entity responsible for making the resource available Bioscientifica Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Diseases of the circulatory (Cardiovascular) system, Physiology https://www.socictopen.socict.org/files/original/f5c11dadb54a1a936546d8c58890d103.pdf 4067ee3b13bd586736a6206c93c0dc7e Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource SARS-CoV-2 and Influenza Virus Coinfection Creator An entity primarily responsible for making the resource Figen Kaptan Description An account of the resource Severe acute respiratory syndrome virus 2 was initially identified in the Chinese city Wuhan on 29 December 2019. The infection hasrapidly spread all over the world, and the World Health Organization declared the infection a pandemic on 11 March 2020. The disease, named coronavirus disease 19, has similar modes of transmission and clinical features with influenza, and coinfections have also been reported during the course of coronavirus disease 19. Studies have shown that the ratio of coinfections ranged widely among studies, and the clinical presentation in coinfections has varied from mild to severe disease leading to death. Detection of coinfection is important in order to plan the optimal treatment and improve clinical outcome. Studies reveal that nonpharmaceutical interventions such as social distancing and changes in population behavior implemented for coronavirus disease 19 have also reduced influenza transmission. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource influenza, covid-19, SARS-CoV-2, Co-infection Identifier An unambiguous reference to the resource within a given context 10.5578/flora.70015 Source A related resource from which the described resource is derived Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi Publisher An entity responsible for making the resource available Bilimsel Tip Yayinevi Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology, Infectious and parasitic diseases https://www.socictopen.socict.org/files/original/d0db64448f51e2fe5cfaf73a9594afb8.pdf a30ff946aee59195cfffd6991908b7a6 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource SARS-CoV-2 and Stroke Characteristics: A Report From the Multinational COVID-19 Stroke Study Group. Creator An entity primarily responsible for making the resource Ronen R Leker, Shima Shahjouei, Georgios Tsivgoulis, Ghasem Farahmand, Eric Koza, Ashkan Mowla, Alireza Vafaei Sadr, Arash Kia, Alaleh Vaghefi Far, Stefania Mondello, Achille Cernigliaro, Annemarei Ranta, Martin Punter, Faezeh Khodadadi, Soheil Naderi, Mirna Sabra, Mahtab Ramezani, Ali Amini Harandi, Oluwaseyi Olulana, Durgesh Chaudhary, Aicha Lyoubi, Bruce C V Campbell, Juan F Arenillas, Daniel Bock, Joan Montaner, Saeideh Aghayari Sheikh Neshin, Diana Aguiar de Sousa, Matthew S Tenser, Ana Aires, Mercedes de Lera Alfonso, Orkhan Alizada, Elsa Azevedo, Nitin Goyal, Zabihollah Babaeepour, Gelareh Banihashemi, Leo H Bonati, Carlo W Cereda, Jason J Chang, Miljenko Crnjakovic, Gian Marco De Marchis, Massimo Del Sette, Seyed Amir Ebrahimzadeh, Mehdi Farhoudi, Ilaria Gandoglia, Bruno Gonçalves, Christoph J Griessenauer, Mehmet Murat Hanci, Aristeidis H Katsanos, Christos Krogias, Lev Lotman, Jeffrey Mai, Shailesh Male, Konark Malhotra, Branko Malojcic, Teresa Mesquita, Asadollah Mir Ghasemi, Hany Mohamed Aref, Zeinab Mohseni Afshar, Jusun Moon, Mika Niemelä, Behnam Rezai Jahromi, Lawrence Nolan, Abhi Pandhi, Jong-Ho Park, João Pedro Marto, Francisco Purroy, Sakineh Ranji-Burachaloo, Nuno Reis Carreira, Manuel Requena, Marta Rubiera, Seyed Aidin Sajedi, João Sargento-Freitas, Vijay K Sharma, Thorsten Steiner, Kristi Tempro, Guillaume Turc, Yasaman Ahmadzadeh, Mostafa Almasi-Dooghaee, Farhad Assarzadegan, Arefeh Babazadeh, Humain Baharvahdat, Fabricio Buchadid Cardoso, Apoorva Dev, Mohammad Ghorbani, Ava Hamidi, Zeynab Sadat Hasheminejad, Sahar Hojjat-Anasri Komachali, Fariborz Khorvash, Firas Kobeissy, Hamidreza Mirkarimi, Elahe Mohammadi-Vosough, Debdipto Misra, Ali Reza Noorian, Peyman Nowrouzi-Sohrabi, Sepideh Paybast, Leila Poorsaadat, Mehrdad Roozbeh, Behnam Sabayan, Saeideh Salehizadeh, Alia Saberi, Mercedeh Sepehrnia, Fahimeh Vahabizad, Thomas Alexandre Yasuda, Mojdeh Ghabaee, Nasrin Rahimian, Mohammad Hossein Harirchian, Afshin Borhani-Haghighi, Mahmoud Reza Azarpazhooh, Rohan Arora, Saeed Ansari, Venkatesh Avula, Jiang Li, Vida Abedi, Ramin Zand Description An account of the resource [Figure: see text]. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource Stroke, venous thrombosis, CEREBROVASCULAR DISORDERS, Neuroimaging, intracranial hemorrhages Identifier An unambiguous reference to the resource within a given context 10.1161/STROKEAHA.120.032927 Source A related resource from which the described resource is derived Stroke https://www.socictopen.socict.org/files/original/080c711e350c009159d8f15babc51a0e.pdf f91241a342ac862bf23ec8577b2a51aa Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource SARS-CoV-2 and the Eye: A Relationship for a Possible Prognostic Tool in COVID-19 Patients Creator An entity primarily responsible for making the resource Gulias-Cañizo R, Ruíz-Leyja ED, Sánchez-Huerta V, Ochoa-de la Paz L Description An account of the resource Rosario Gulias-Ca&ntilde;izo,1 Estela D&rsquo;Abril Ru&iacute;z-Leyja,2 Valeria S&aacute;nchez-Huerta,2 Lenin Ochoa-de la Paz2,3 1Facultad de Ciencias de la Salud, Universidad An&aacute;huac M&eacute;xico, Huixquilucan, Edo. de M&eacute;xico, M&eacute;xico; 2Asociaci&oacute;n Para Evitar la Ceguera en M&eacute;xico I.A.P. Hospital Dr. Luis S&aacute;nchez Bulnes, Mexico City, 04020, Mexico; 3Departamento de Bioqu&iacute;mica, Facultad de Medicina, Universidad Nacional Aut&oacute;noma de M&eacute;xico, Mexico City, 04510, MexicoCorrespondence: Lenin Ochoa-de la Paz Email ochoadelapaz@yahoo.com.mxPurpose: In December 2019 there was the first report about a new viral infection in Wuhan, China. The new virus was taxonomically designed as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) causing the coronavirus disease 2019 (COVID-19). SARS-CoV-2 uses the angiotensin-converting enzyme 2 (ACE2) receptor for cell invasion, which is expressed in different tissues including lungs, small intestine, testicles, kidneys, brain, and the eye. The purpose of this article is to review the available information on the relationship of COVID-19 with the eye, as well as evaluating the possible usefulness of ocular diagnostic tests to help in the diagnosis and/or monitoring of patients with this disease.Methods: We performed a retrospective review of relevant articles from November 2019 to April 2020.Results: Ocular infection by SARS-CoV-2 is still controversial; nevertheless, the possibility of being a viral reservoir has been suggested, increasing the likelihood of infection. Some reports demonstrated the presence of SARS-CoV-2 in tears, and previously published data suggest a pathological increase of cytokine concentrations in COVID-19 patients; the cytokine release syndrome or cytokine storm contributes to lung and central nervous system damage. The usefulness of tears for the measurement of inflammatory cytokines in various diseases is well known, in particular IL-6, which has been correlated to the severity of COVID-19.Conclusion: Considering that the IL-6 signaling cascade may be activated in patients with COVID-19, makes it an excellent target for diagnostic and/or monitoring purposes.Keywords: eye, SARS-COV-2, COVID-19, tear film, IL-6, cytokine release syndrome, tear sampling Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource covid-19, SARS-CoV-2, Cytokine release syndrome, IL-6, eye, tear film, Tear sampling Source A related resource from which the described resource is derived Biotemas Publisher An entity responsible for making the resource available Universidade Federal de Santa Catarina Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Ophthalmology https://www.socictopen.socict.org/files/original/26394ab29c955b18fdd873b0752d8ce3.pdf 82f426042287c856cd0004dcea6874b5 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource SARS-CoV-2 and the Use of Chloroquine as an Antiviral Treatment Creator An entity primarily responsible for making the resource Mathieu E. Rebeaud, Florian Zores Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource COVID-19, SARS-CoV-2, chloroquine, antiviral, 2019ncov Identifier An unambiguous reference to the resource within a given context DOI: 10.3389/fmed.2020.00184 Source A related resource from which the described resource is derived Frontiers in Medicine Publisher An entity responsible for making the resource available Frontiers Media S.A. Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine (General) Language A language of the resource EN https://www.socictopen.socict.org/files/original/17880f9cf7759bf1d31e13e70383ab9d.pdf d63f9808f2fa81074b89a54d4d99efdf Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource SARS-CoV-2 Antibody Screening in Healthcare Workers in Non-Infectious Hospitals in Two Different Regions of Southern Poland (Upper Silesia and Opole Voivodeships): A Prospective Cohort Study Creator An entity primarily responsible for making the resource Rafał Jakub Bułdak, Elżbieta Woźniak-Grygiel, Marta Wąsik, Janusz Kasperczyk, Ewa Gawrylak-Dryja, Renata Mond-Paszek, Adam Konka, Karina Badura-Brzoza, Martyna Fronczek, Marlena Golec, Mateusz Lejawa, Marcin Markiel, Sławomir Kasperczyk, Zenon Brzoza Description An account of the resource (1) Background: Detection of asymptomatic or subclinical human coronavirus SARS-CoV-2 infection in healthcare workers (HCWs) is crucial for understanding the overall prevalence of the new coronavirus and its infection potential in public (non-infectious) healthcare units with emergency wards. (2) Methods: We evaluated the host serologic responses, measured with semi-quantitative ELISA tests (IgA, IgG, IgM abs) in sera of 90 individuals in Hospital no. 4 in Bytom, 84 HCWs in the University Hospital in Opole and 25 in a Miasteczko Śląskie local surgery. All volunteers had negative RT-PCR test results or had not had the RT-PCR test performed within 30 days before sampling. The ELISA test was made at two different time points (July/August 2020) with a 2-weeks gap between blood collections to avoid the “serological window” period. (3) Results: The IgG seropositivity of asymptomatic HCWs varied between 1.2% to 10% (Opole vs. Bytom, p < 0.05; all without any symptoms). IgA seropositivity in HCWs was 8.8% in Opole and 7.14% in Bytom. IgM positive levels in HCWs in Opole and Bytom was 1.11% vs. 2.38%, respectively. Individuals with IgA and IgM seropositivity results were observed only in Opole (1.19%). More studies are needed to determine whether these results are generalizable to other populations and geographic as well as socio-demographic locations. (4) Conclusions: 100% of IgG(+) volunteers were free from any symptoms of infection in the 30 days before first or second blood collection and they had no awareness of SARS-CoV-2 infection. Asymptomatic HCWs could spread SARS-CoV-2 infection to other employees and patients. Only regular HCWs RT-PCR testing can reduce the risk of SARS-CoV-2 spreading in a hospital environment. The benefit of combining the detection of specific IgA with that of combined specific IgM/IgG is still uncertain. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource Serological surveillance, covid-19, RT-PCR, SARS-CoV-2, Health care professionals, Asymptomatic Identifier An unambiguous reference to the resource within a given context 10.3390/ijerph18084376 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine https://www.socictopen.socict.org/files/original/20ee44acd3bf6aa10e5c66478196afea.pdf bc41d1fc6f76b1f959a47ac0be4331a4 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource SARS-CoV-2 antibody-based SURVEILLANCE: New light in the SHADOW. Creator An entity primarily responsible for making the resource Mario Plebani Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.1016/j.ebiom.2020.103087 Source A related resource from which the described resource is derived EBioMedicine https://www.socictopen.socict.org/files/original/c117200a3dc6b48c11987c6b3937cd46.pdf 0160d69bd8bacc03fb339e7853d3f22d Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource SARS-CoV-2 antibody-positivity protects against reinfection for at least seven months with 95% efficacy. Creator An entity primarily responsible for making the resource Andrew Jeremijenko, Peter Coyle, Abdullatif Al Khal, Ayeda A. Ahmed, Yasmin A. Mohamoud, Shameem Younuskunju, Houssein H. Ayoub, Zaina Al Kanaani, Einas Al Kuwari, Anvar Hassan Kaleeckal, Ali Nizar Latif, Riyazuddin Mohammad Shaik, Hanan F. Abdul Rahim, Mohamed Ghaith Al Kuwari, Hamad Eid Al Romaihi, Mohamed H. Al-Thani, Roberto Bertollini, Gheyath K Nasrallah, Laith J Abu-Raddad, Hiam Chemaitelly, Joel A Malek, Adeel A Butt, Hadi M Yassine Description An account of the resource Reinfection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been documented, raising public health concerns. SARS-CoV-2 reinfections were assessed in a cohort of antibody-positive persons in Qatar. All SARS-CoV-2 antibody-positive persons from April 16 to December 31, 2020 with a PCR-positive swab ≥14 days after the first-positive antibody test were investigated for evidence of reinfection. Viral genome sequencing was conducted for paired viral specimens to confirm reinfection. Incidence of reinfection was compared to incidence of infection in the complement cohort of those who were antibody-negative. Among 43,044 antibody-positive persons who were followed for a median of 16.3 weeks (range: 0-34.6), 314 individuals (0.7%) had at least one PCR positive swab ≥14 days after the first-positive antibody test. Of these individuals, 129 (41.1%) had supporting epidemiological evidence for reinfection. Reinfection was next investigated using viral genome sequencing. Applying the viral-genome-sequencing confirmation rate, the incidence rate of reinfection was estimated at 0.66 per 10,000 person-weeks (95% CI: 0.56-0.78). Incidence rate of reinfection versus month of follow-up did not show any evidence of waning of immunity for over seven months of follow-up. Meanwhile, in the complement cohort of 149,923 antibody-negative persons followed for a median of 17.0 weeks (range: 0-45.6), incidence rate of infection was estimated at 13.69 per 10,000 person-weeks (95% CI: 13.22-14.14). Efficacy of natural infection against reinfection was estimated at 95.2% (95% CI: 94.1-96.0%). Reinfections were less severe than primary infections. Only one reinfection was severe, two were moderate, and none were critical or fatal. Most reinfections (66.7%) were diagnosed incidentally through random or routine testing, or through contact tracing. Reinfection is rare in the young and international population of Qatar. Natural infection appears to elicit strong protection against reinfection with an efficacy ~95% for at least seven months. Biomedical Research Program, the Biostatistics, Epidemiology, and Biomathematics Research Core, and the Genomics Core, all at Weill Cornell Medicine-Qatar, the Ministry of Public Health, Hamad Medical Corporation, and the Qatar Genome Programme. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource epidemiology, immunity, SARS-CoV-2, Reinfection, genetics Identifier An unambiguous reference to the resource within a given context 10.1016/j.eclinm.2021.100861 Source A related resource from which the described resource is derived EClinicalMedicine