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                <text>Susan A. Shriner, Jeremy W. Ellis, J. Jeffrey Root, Annette Roug, Scott R. Stopak, Gerald W. Wiscomb, Jared R. Zierenberg, Hon S. Ip, Mia K. Torchetti, Thomas J. DeLiberto</text>
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                <text>In August 2020, outbreaks of coronavirus disease were confirmed on mink farms in Utah, USA. We surveyed mammals captured on and around farms for evidence of infection or exposure. Free-ranging mink, presumed domestic escapees, exhibited high antibody titers, suggesting a potential severe acute respiratory syndrome coronavirus 2 transmission pathway to native wildlife.</text>
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                <text>SARS-CoV-2 from Urban to Rural Water Environment: Occurrence, Persistence, Fate and Influence on Agriculture Irrigation. A Review</text>
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                <text>Giuseppe Mancuso, Giulio Demetrio Perulli, Stevo Lavrnić, Brunella Morandi, Attilio Toscano</text>
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                <text>The novel coronavirus disease (COVID-19), originating from China, has rapidly crossed borders, infecting people worldwide. While its transmission may occur predominantly via aerosolization of virus-laden droplets, the possibility of other routes of contagion via the environment necessitates considerable scientific consideration. SARS-CoV-2 viral RNA has been detected in the feces of infected persons, and studies also have reported its occurrence in wastewater and surface water bodies. Therefore, water may be a possible route of virus outbreaks. Agricultural irrigation is the largest use of water globally, accounting for 70% of water use worldwide. Ensuring adequate water quality within irrigation practices is fundamental to prevent harm to plants and soils, maintain food safety, and protect public health. This review aims to gather information on possible SARS-CoV-2 transmission routes within urban and rural water environments, looking into the detection, persistence, and fate of SARS-CoV-2. Based on published literature, the effect of current treatment technologies in wastewater treatment plants (WWTPs) on SARS-CoV-2 inactivation has also been investigated. Preliminary research efforts that concentrated on SARS-CoV-2 indicate that the risk of virus transmission from the aquatic environment may currently be non-existent, although a few studies have reported the presence of SARS-CoV RNA in soils, whereas there are still no studies on the detection of SARS-CoV-2 in crops.</text>
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                <text>coronavirus, covid-19, SARS-CoV-2, waste water, water reuse, reclaimed water</text>
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                <text>Epidemiology and Health</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Hydraulic engineering, Water supply for domestic and industrial purposes</text>
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                <text>Tamano Matsui, Makoto Kuroda, Tsuyoshi Sekizuka, Michiyo Shinohara, Yusuke Kobayashi, Hajime Kamiya, Yushi Hachisu, Motoi Suzuki, Akihiko Tokaji, Masakatsu Taira, Kentaro Itokawa, Keisuke Kadokura, Sanae Kuramoto, Eri Nariai, Tsuyoshi Kishimoto</text>
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                <text>Japan has reported 26 cases of coronavirus disease 2019 (COVID-19) linked to cruise tours on the River Nile in Egypt between March 5 and 15, 2020. Here, we characterized the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome of isolates from 10 travelers who returned from Egypt and from patients possibly associated with these travelers. We performed haplotype network analysis of SARS-CoV-2 isolates using genome-wide single-nucleotide variations. Our analysis identified two potential Egypt-related clusters from these imported cases, and these clusters were related to globally detected viruses in different countries.</text>
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                <text>imported case, cruise ship, haplotype network, genome epidemiology, Single nucleotide variations</text>
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                <text>DOI: 10.3389/fmicb.2020.01316</text>
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                <text>Frontiers in Microbiology</text>
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                <text>Frontiers Media S.A.</text>
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                <text>Microbiology</text>
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                <text>SARS-CoV-2 genomics: An Indian perspective on sequencing viral variants.</text>
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                <text>Since its emergence as a pneumonia-like outbreak in the Chinese city of Wuhan in late 2019, the novel coronavirus disease COVID-19 has spread widely to become a global pandemic. The first case of COVID-19 in India was reported on 30 January 2020 and since then it has affected more than ten million people and resulted in around 150,000 deaths in the country. Over time, the viral genome has accumulated mutations as it passes through its human hosts, a common evolutionary mechanism found in all microorganisms. This has implications for disease surveillance and management, vaccines and therapeutics, and the emergence of reinfections. Sequencing the viral genome can help monitor these changes and provides an extraordinary opportunity to understand the genetic epidemiology and evolution of the virus as well as tracking its spread in a population. Here we review the past year in the context of the phylogenetic analysis of variants isolated over the course of the pandemic in India and highlight the importance of continued sequencing-based surveillance in the country.</text>
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                <text>SARS-CoV-2 ile İlişkili Akut Böbrek Hasarı</text>
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                <text>Dede Şit, Hasan Kayabaşı</text>
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                <text>2019 yılının sonunda Çin'de patlak veren yeni tip koronavirüs (COVID-19) çok kısa sürede küresel bir salgın halini aldı.COVID-19 infeksiyonu esas olarak solunum sistemini etkilemekle birlikte, şiddetli akciğer tutulumu olan olgularda ileriyaş, diyabet, hipertansiyon, kardiyovasküler hastalık, kronik böbrek hastalığı (KBH) gibi yüksek risk grubundakihastalarda böbrek tutulumu sık görülmektedir. Akut böbrek hasarı (ABH), COVID-19 infeksiyonunun majörkomplikasyonlarından biridir, KBH olanlarda daha sık görülmektedir ve artmış morbidite ve mortalite ile ilişkilidir. ABH gelişen olgularda kalıcı böbrek hasarı riski artmıştır. Özellikle COVID-19 infeksiyonu sırasında böbrek fonksiyonlarının dikkatle kontrol edilmesi ve süreç içinde yakın izlem gerektiği, halen etkin bir tedavisi olmayan bu pandemik infeksiyon için yaşamsal önemdedir. Bu derlemede COVID-19 seyri sırasında gelişebilecek böbrek tutulumu ve akut böbrek hasarı tartışılmıştır.</text>
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                <text>covid-19, böbrek fonksiyonları, akut böbrek hasarı</text>
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                <text>SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical Practice</text>
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                <text>Introduction: COVID-19 is caused by the coronavirus SARS-CoV-2. Ocular manifestations have been reported including conjunctivitis and retinal changes. Therefore, it is of the utmost importance to clarify eye involvement in COVID-19 in order to help with its diagnosis and to further prevent its transmission. The purpose of this review is to describe the structure and transmission of SARS-CoV-2, reported ocular findings and protection strategies for ophthalmologists. Material and Methods: Literature search on PubMed for relevant articles using the keywords ‘COVID-19’, ‘coronavirus’, and ‘SARS-CoV-2’ in conjunction with ‘ophthalmology’ and ‘eye’. Moreover, official recommendations of ophthalmological societies were reviewed. Results: Although the conjunctiva is directly exposed to extraocular pathogens, and the mucosa of the ocular surface and upper respiratory tract are connected by the nasolacrimal duct, the eye is rarely involved in human SARS-CoV-2 infection and the SARS-CoV-2 RNA positive rate by RT-PCR test in tears and conjunctival secretions from patients with COVID-19 is also extremely low. Discussion: The eye can be affected by SARS-CoV-2, which is supported by some reports of conjunctivitis and retinal changes, but its role in the spread of the disease is still unknown. Conclusion: Given the current scarce evidence, more research is needed to clarify the relationship between SARS-CoV-2 and the eye.</text>
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                <text>10.20344/amp.14118</text>
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                <text>Acta Médica Portuguesa</text>
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                <text>Ordem dos Médicos</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>SARS-CoV-2 in Pregnancy: A Comprehensive Summary of Current Guidelines</text>
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                <text>Rodrigo Ruano, Gabriele Tonni, Olivier Picone, Ayssa Teles Abrao Trad, Elena Carreras, Mark Kilby, Ramon Escuriet, Regan Theiler, Anna Suy, Kavita Narang, Eniola R. Ibirogba, Amro Elrefaei, Roseli Nomura</text>
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                <text>Since the declaration of the global pandemic of COVID-19 by the World Health Organization on 11 March 2020, we have continued to see a steady rise in the number of patients infected by SARS-CoV-2. However, there is still very limited data on the course and outcomes of this serious infection in a vulnerable population of pregnant patients and their fetuses. International perinatal societies and institutions including SMFM, ACOG, RCOG, ISUOG, CDC, CNGOF, ISS/SIEOG, and CatSalut have released guidelines for the care of these patients. We aim to summarize these current guidelines in a comprehensive review for patients, healthcare workers, and healthcare institutions. We included 15 papers from 10 societies through a literature search of direct review of society’s websites and their journal publications up till 20 April 2020. Recommendations specific to antepartum, intrapartum, and postpartum were abstracted from the publications and summarized into Tables. The summary of guidelines for the management of COVID-19 in pregnancy across different perinatal societies is fairly consistent, with some variation in the strength of recommendations. It is important to recognize that these guidelines are frequently updated, as we continue to learn more about the course and impact of COVID-19 in pregnancy.</text>
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                <text>Guidelines, Pregnancy, coronavirus, Pandemic, SARS-CoV-2, COVID-19</text>
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                <text>DOI: 10.3390/jcm9051521</text>
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                <text>Journal of Clinical Medicine</text>
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                <text>MDPI AG</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Medicine</text>
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                <text>SARS-CoV-2 in the ocular surface of COVID-19 patients</text>
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                <text>Lin Wang, Xin Liu, Bing Xu, Kangkang Xu, Hua-Tao Xie, Ming-Chang Zhang, Shi-Yun Jiang</text>
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                <text>Abstract The 2019 novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally, while the routes of transmission of this virus are still controversial. We enrolled 33 patients, without any ocular manifestation, with their ocular surface swabs collected for virus detection. RNA was detected strong positive in samples of both eyes from two patients. Therefore, SARS-CoV-2 may exist in the normal ocular surface of COVID-19 patients, suggesting that this virus might be spread through conjunctival contact.</text>
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                <text>ocular surface, SARS-CoV-2, COVID-19</text>
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                <text>DOI: 10.1186/s40662-020-00189-0</text>
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                <text>Eye and Vision</text>
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                <text>Ophthalmology</text>
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                <text>Peter C. Hayes, Kay Samuel, John N. Plevris, Katie Morgan, Martin Vandeputte</text>
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                <text>A novel strain of coronoviridae (SARS-CoV-2) was reported in Wuhan China in December 2019. Initially, infection presented with a broad spectrum of symptoms which typically included muscle aches, fever, dry cough, and shortness of breath. SARS-CoV-2 enters cells via ACE2 receptors which are abundant throughout the respiratory tract. However, there is evidence that these receptors are abundant throughout the body, and just as abundant in cholangiocytes as alveolar cells, posing the question of possible direct liver injury. While liver enzymes and function tests do seem to be deranged in some patients, it is questionable if the injury is due to direct viral damage, drug-induced liver injury, hypoxia, or microthromboses. Likely, the injury is multifactoral, and management of infected patients with pre-existing liver disease should be taken into consideration. Ultimately, a vaccine is needed to aid in reducing cases of SARS-CoV-2 and providing immunity to the general population. However, while considering the types of vaccines available, safety concerns, particularly of RNA- or DNA-based vaccines, need to be addressed.</text>
              </elementText>
            </elementTextContainer>
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          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="32599">
                <text>2020</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="32600">
                <text>Liver, Drug-Induced Liver Injury, SARS-CoV-2, COVID-19, Microthromboses, viral damage</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="32601">
                <text>DOI: 10.3390/pathogens9060430</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="32602">
                <text>Pathogens</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="32603">
                <text>MDPI AG</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="32604">
                <text>Medicine</text>
              </elementText>
            </elementTextContainer>
          </element>
        </elementContainer>
      </elementSet>
    </elementSetContainer>
  </item>
</itemContainer>
