1735 10 20655 https://www.socictopen.socict.org/files/original/b34d3f4d492f5d4edf794732dc23cf0e.pdf 2868948a8f597d5d00193e4ea172eccc Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Interventions for treatment of COVID-19: a protocol for a living systematic review with network meta-analysis including individual patient data (The LIVING Project) Creator An entity primarily responsible for making the resource Lehana Thabane, Christian Gluud, Areti Angeliki Veroniki, Niklas Nielsen, Janus Christian Jakobsen, Adam Linder, Peter Bentzer, Sophie Juul, Sarah Klingenberg Description An account of the resource Abstract Background COVID-19 is a rapidly spreading virus infection that has quickly caused extensive burden to individual, families, countries, and the globe. No intervention has yet been proven effective for the treatment of COVID-19. Some randomized clinical trials assessing the effects of different drugs have been published, and more are currently underway. There is an urgent need for a living, dynamic systematic review that continuously evaluates the beneficial and harmful effects of all available interventions for COVID-19. Methods/design We will conduct a living systematic review based on searches of major medical databases (e.g., MEDLINE, EMBASE, CENTRAL) and clinical trial registries from their inception onwards to identify relevant randomized clinical trials. We will update the literature search once a week to continuously assess if new evidence is available. Two review authors will independently extract data and perform risk of bias assessment. We will include randomized clinical trials comparing any intervention for the treatment of COVID-19 (e.g., pharmacological interventions, fluid therapy, invasive or noninvasive ventilation, or similar interventions) with any comparator (e.g., an “active” comparator, standard care, placebo, no intervention, or “active placebo”) for participants in all age groups with a diagnosis of COVID-19. Primary outcomes will be all-cause mortality and serious adverse events. Secondary outcomes will be admission to intensive care, mechanical ventilation, renal replacement therapy, quality of life, and non-serious adverse events. The living systematic review will include aggregate data meta-analyses, Trial Sequential Analyses, network meta-analysis, and individual patient data meta-analyses. Risk of bias will be assessed with domains, an eight-step procedure will be used to assess if the thresholds for clinical significance are crossed, and the certainty of the evidence will be assessed by Grading of Recommendations, Assessment, Development and Evaluations (GRADE). Discussion COVID-19 has become a pandemic with substantial mortality. A living systematic review evaluating the beneficial and harmful effects of pharmacological and other interventions is urgently needed. This review will continuously inform best practice in treatment and clinical research of this highly prevalent disease. Systematic review registration PROSPERO CRD42020178787 Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/s13643-020-01371-0 Source A related resource from which the described resource is derived Systematic Reviews Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine https://www.socictopen.socict.org/files/original/e7e7bceb8511e77f087fc669f180f707.pdf 5dc1bdc5e1c358e4ee0011b5fc1125b5 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Challenges in maintaining treatment services for people who use drugs during the COVID-19 pandemic Creator An entity primarily responsible for making the resource John Ryan, Paul Haber, Michelle Hall, Lisa Maher, Peter Saul, Adrian Dunlop, Nicholas Lintzeris, Buddhima Lokuge, Debbie Masters, Marcia Sequeira, Grace Dunlop, Nadine Ezard Description An account of the resource Abstract The impact of COVID-19 across health services, including treatment services for people who use drugs, is emerging but likely to have a high impact. Treatment services for people who use drugs provide essential treatment services including opiate agonist treatment and needle syringe programmes alongside other important treatment programmes across all substance types including withdrawal and counselling services. Drug and alcohol hospital consultation-liaison clinicians support emergency departments and other services provided in hospital settings in efficiently managing patients who use drugs and present with other health problems. COVID-19 will impact on staff availability for work due to illness. Patients may require home isolation and quarantine periods. Ensuring ongoing supply of opiate treatment during these periods will require significant changes to how treatment is provided. The use of monthly depot buprenorphine as well as moving from a framework of supervised dosing will be required for patients on sublingual buprenorphine and methadone. Ensuring ready access to take-home naloxone for patients is crucial to reduce overdose risks. Delivery of methadone and buprenorphine to the homes of people with confirmed COVID-19 infections is likely to need to occur to support home isolation. People who use drugs are likely to be more vulnerable during the COVID-19 epidemic, due to poorer health literacy and stigma and discrimination towards this group. People who use drugs may prioritise drug use above other health concerns. Adequate supply of clean injecting equipment is important to prevent outbreaks of blood-borne viruses. Opiate users may misinterpret SARS-CoV2 symptoms as opiate withdrawal and manage this by using opioids. Ensuring people who use drugs have access to drug treatment as well as access to screening and testing for SARS-CoV2 where this is indicated is important. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/s12954-020-00370-7 Source A related resource from which the described resource is derived Harm Reduction Journal Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Public aspects of medicine https://www.socictopen.socict.org/files/original/ad148ba4aec301147ea703b1d20dcedf.pdf 2136ad64c7d275a600d75d79b558cfa3 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Tocilizumab for Treatment of Severe COVID-19 Patients: Preliminary Results from SMAtteo COvid19 REgistry (SMACORE) Creator An entity primarily responsible for making the resource Carlomaurizio Montecucco, Emanuele Maria Giusti, Valentina Zuccaro, Raffaele Bruno, Francesco Mojoli, Paolo Sacchi, Marta Colaneri, Laura Bogliolo, Pietro Valsecchi, Fabio Brandolino, the COVID IRCCS San Matteo Pavia Task Force Description An account of the resource Objective: This study aimed to assess the role of Tocilizumab therapy (TCZ) in terms of ICU admission and mortality rate of critically ill patients with severe COVID-19 pneumonia. Design: Patients with COVID-19 pneumonia were prospectively enrolled in SMAtteo COvid19 REgistry (SMACORE). A retrospective analysis of patients treated with TCZ matched using propensity score to patients treated with Standard Of Care (SOC) was conducted. Setting: The study was conducted at IRCCS Policlinico San Matteo Hospital, Pavia, Italy, from March 14, 2020 to March 27, 2020. Participants: Patients with a confirmed diagnosis of COVID-19 hospitalized in our institution at the time of TCZ availability. Interventions: TCZ was administered to 21 patients. The first administration was 8 mg/kg (up to a maximum 800 mg per dose) of Tocilizumab intravenously, repeated after 12 h if no side effects were reported after the first dose. Main Outcomes and Measures: ICU admission and 7-day mortality rate. Secondary outcomes included clinical and laboratory data. Results: There were 112 patients evaluated (82 were male and 30 were female, with a median age of 63.55 years). Using propensity scores, the 21 patients who received TCZ were matched to 21 patients who received SOC (a combination of hydroxychloroquine, azithromycin and prophylactic dose of low weight heparin). No adverse event was detected following TCZ administration. This study found that treatment with TCZ did not significantly affect ICU admission (OR 0.11; 95% CI between 0.00 and 3.38; p = 0.22) or 7-day mortality rate (OR 0.78; 95% CI between 0.06 and 9.34; p = 0.84) when compared with SOC. Analysis of laboratory measures showed significant interactions between time and treatment regarding C-Reactive Protein (CRP), alanine aminotransferase (ALT), platelets and international normalized ratio (INR) levels. Variation in lymphocytes count was observed over time, irrespective of treatment. Conclusions: TCZ administration did not reduce ICU admission or mortality rate in a cohort of 21 patients. Additional data are needed to understand the effect(s) of TCZ in treating patients diagnosed with COVID-19. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Mortality Rate, Tocilizumab, ICU, Propensity score matching, Off-label therapy, COVID-19 pneumonia Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/microorganisms8050695 Source A related resource from which the described resource is derived Microorganisms Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General) https://www.socictopen.socict.org/files/original/d842ffb8e95acaa96a81839637bbb9bc.pdf 0d15e47e36be06c4d1e6033355ee08bd Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Using Probiotics to Flatten the Curve of Coronavirus Disease COVID-2019 Pandemic Creator An entity primarily responsible for making the resource Eric Giannoni, Glenn R. Gibson, Gregor Reid, David Baud, Varvara Dimopoulou Agri Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Probiotics, prebiotics, coronavirus, Pandemics, SARS-CoV-2, COVID-19 Identifier An unambiguous reference to the resource within a given context DOI: 10.3389/fpubh.2020.00186 Source A related resource from which the described resource is derived Frontiers in Public Health Publisher An entity responsible for making the resource available Frontiers Media S.A. Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Public aspects of medicine https://www.socictopen.socict.org/files/original/35c2a4c64cfd81615b2c4327f2566145.pdf a8b2cb649562c6d0a77c970d6a0576ba Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Medical Device-Related Pressure Injury in health care professionals in times of pandemic Creator An entity primarily responsible for making the resource Paula de Souza Silva Freitas, Paula Cristina Nogueira, Aline Oliveira Ramalho Description An account of the resource Facing the number of cases of coronavirus infection (COVID-19), the World Health Organization (WHO) has declared that the disease, present in several countries and continents, is a pandemic of global alert and mobilization1. In Brazil, the pandemic arrived at the end of February 2020 and has been causing alarm due to the increase in the number of contaminated people related to the high capacity of transmission of the disease. In affected patients, the virus can cause from simple symptoms, which can be treated at home, to hospital admissions, assistance in intensive care units and can even lead to death2. In the midst of this pandemic, the professionals who assist patients with suspected or confirmed COVID-19 infection constitute a population at high risk of contagion. In this way, preventive measures such as adequate hand hygiene and the use of personal protective equipment(PPE) have been reinforced. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource - Identifier An unambiguous reference to the resource within a given context DOI: https://doi.org/10.30886/estima.v18.867_IN Source A related resource from which the described resource is derived Estima Publisher An entity responsible for making the resource available Associação Brasileira de Estomaterapia Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Nursing https://www.socictopen.socict.org/files/original/256d544108f4f45820992cb6cae47f1b.pdf 375eb86c90f1c2a7ea42654f3214afe3 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource How the Italian NHS Is Fighting Against the COVID-19 Emergency Creator An entity primarily responsible for making the resource Walter Ricciardi, Stefania Boccia, Martin McKee, Fidelia Cascini Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Italy, emergency, Pandemic, healthcare systems, COVID-19 Identifier An unambiguous reference to the resource within a given context DOI: 10.3389/fpubh.2020.00167 Source A related resource from which the described resource is derived Frontiers in Public Health Publisher An entity responsible for making the resource available Frontiers Media S.A. Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Public aspects of medicine https://www.socictopen.socict.org/files/original/5abb24cadf05f1c030250521dcb1e9b8.pdf 6f7e94dcd315dda2e2526f18b9ef8210 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The challenges facing indigenous communities in Latin America as they confront the COVID-19 pandemic Creator An entity primarily responsible for making the resource Blanca Estela Pelcastre-Villafuerte, Roberto Campos Navarro, Sergio Meneses Navarro, Liliana Gómez-Flores-Ramos, María Graciela Freyermuth Enciso, David Mariano Meléndez-Navarro Description An account of the resource Resumen La pandemia de coronavirus 2019 (COVID-19) golpeó a América Latina a fines de febrero y ahora está comenzando a extenderse por las comunidades indígenas y rurales de la región, hogar de 42 millones de personas. El 80% de esta población altamente marginada se concentra en Bolivia, Guatemala, México y Perú. Los servicios de atención médica para estos grupos étnicos enfrentan desafíos distintos en vista de sus altos niveles de marginación y diferencias culturales de la mayoría. Con más de 30 años de trabajo e investigación sobre las respuestas de los sistemas de salud dirigida a las comunidades indígenas de América Latina, consideramos que los países de la región deben estar preparados para combatir la epidemia en contextos indígenas marcados por la privación y la disparidad social. Discutimos cuatro desafíos principales que deben ser abordados por los gobiernos para garantizar la salud y la vida de los que se encuentran en la parte inferior de la estructura social: los pueblos indígenas de la región. Este análisis proporciona una guía práctica para diseñar e implementar una respuesta a COVID-19 en comunidades indígenas. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Latin America, indigenous populations, COVID-19, Health systems response Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/s12939-020-01178-4 Source A related resource from which the described resource is derived International Journal for Equity in Health Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Public aspects of medicine https://www.socictopen.socict.org/files/original/bfbf083208dc469d5023b81c81a9c63a.pdf c422646f2727f6765d716b9df92a0d78 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Porcine Epidemic Diarrhea Virus and the Host Innate Immune Response Creator An entity primarily responsible for making the resource Sha-sha Li, Zixiang Zhu, Haixue Zheng, Jinping Yang Description An account of the resource Porcine epidemic diarrhea virus (PEDV), a swine enteropathogenic coronavirus (CoV), is the causative agent of porcine epidemic diarrhea (PED). PED causes lethal watery diarrhea in piglets, which has led to substantial economic losses in many countries and is a great threat to the global swine industry. Interferons (IFNs) are major cytokines involved in host innate immune defense, which induce the expression of a broad range of antiviral effectors that help host to control and antagonize viral infections. PEDV infection does not elicit a robust IFN response, and some of the mechanisms used by the virus to counteract the host innate immune response have been unraveled. PEDV evades the host innate immune response by two main strategies including: (1) encoding IFN antagonists to disrupt innate immune pathway, and (2) hiding its viral RNA to avoid the exposure of viral RNA to immune sensors. This review highlights the immune evasion mechanisms employed by PEDV, which provides insights for the better understanding of PEDV-host interactions and developing effective vaccines and antivirals against CoVs. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Immune Evasion, Innate Immunity, coronavirus, type I IFN, porcine epidemic diarrhea virus Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/pathogens9050367 Source A related resource from which the described resource is derived Pathogens Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine https://www.socictopen.socict.org/files/original/ec734b1ce9ea47038ad134a1b5349dbf.pdf 79c2d6b2e3064117c0ef851c21e35bb9 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Virus zoonóticos emergentes en un mundo globalizado: SARSCoV- 2/COVID-19 y sus implicaciones en salud pública y en la industria alimentaria Creator An entity primarily responsible for making the resource Francisco José Sánchez-Muniz, María del Rosario Martín de Santos Description An account of the resource - Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource zoonosis, seguridad alimentaria, pandemia, SARS-CoV-2, COVID-19 Identifier An unambiguous reference to the resource within a given context DOI: 10.19230/jonnpr.3741 Source A related resource from which the described resource is derived Jounal of Negative and No Positive Results Publisher An entity responsible for making the resource available Asociación Para el Progreso de la Biomedicina Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Science, Medicine https://www.socictopen.socict.org/files/original/d9e3b77cada4321ea2977a03423a4682.pdf 2cc9d731e4f6684c7a05d06789d7ac53 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Novel, Inexpensive Portable Respiratory Protection Unit (PRPU) for Healthcare Workers Creator An entity primarily responsible for making the resource Christopher S. Sampson, Adam Beckett Description An account of the resource Introduction: Given concern for increased aerosolization during intubation of patients with severe acute respiratory syndrome coronavirus, we sought to create a portable, inexpensive, and easily constructed device to help protect healthcare workers. Methods: A respiratory protection unit can be constructed in approximately 30 minutes and for less than 50 United States dollars in materials, using polyvinylchloride pipe and automobile collision wrap. Conclusion: This device provides possible increased protection during video laryngoscopy and can easily be replicated. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context DOI: 10.5811/cpcem.2020.4.47443 Source A related resource from which the described resource is derived Clinical Practice and Cases in Emergency Medicine Publisher An entity responsible for making the resource available eScholarship Publishing, University of California Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medical emergencies. Critical care. Intensive care. First aid