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                  <text>Dominio científico: Coronavirus</text>
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                <text>Hypertension, Thrombosis, Kidney Failure, and Diabetes: Is COVID-19 an Endothelial Disease? A Comprehensive Evaluation of Clinical and Basic Evidence</text>
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                <text>Celestino Sardu, Raffaele Marfella, Marco Bruno Morelli, Xujun Wang, Jessica Gambardella, Gaetano Santulli</text>
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                <text>The symptoms most commonly reported by patients affected by coronavirus disease (COVID-19) include cough, fever, and shortness of breath. However, other major events usually observed in COVID-19 patients (e.g., high blood pressure, arterial and venous thromboembolism, kidney disease, neurologic disorders, and diabetes mellitus) indicate that the virus is targeting the endothelium, one of the largest organs in the human body. Herein, we report a systematic and comprehensive evaluation of both clinical and preclinical evidence supporting the hypothesis that the endothelium is a key target organ in COVID-19, providing a mechanistic rationale behind its systemic manifestations.</text>
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                <text>Blood Pressure, Acute kidney injury, coronavirus, ACE2, Cytokine storm, COVID, catepsin</text>
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                <text>DOI: 10.3390/jcm9051417</text>
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                <text>Journal of Clinical Medicine</text>
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                <text>Medicine</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Prognostic Value of Cardiovascular Biomarkers in COVID-19: A Review</text>
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                <text>Brian Wang, Ashiq Abdul Khader, Maryam Aboughdir, Thomas Kirwin</text>
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                <text>In early December 2019, the coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) first emerged in Wuhan, China. As of May 10th, 2020, a total of over 4 million COVID-19 cases and 280,000 deaths have been reported globally, reflecting the raised infectivity and severity of this virus. Amongst hospitalised COVID-19 patients, there is a high prevalence of established cardiovascular disease (CVD). There is evidence showing that COVID-19 may exacerbate cardiovascular risk factors and preexisting CVD or may lead to cardiovascular complications. With intensive care units operating at maximum capacity and such staggering mortality rates reported, it is imperative during this time-sensitive COVID-19 outbreak to identify patients with an increased risk of adverse outcomes and/or myocardial injury. Preliminary findings from COVID-19 studies have shown the association of biomarkers of acute cardiac injury and coagulation with worse prognosis. While these biomarkers are recognised for CVD, there is emerging prospect that they may aid prognosis in COVID-19, especially in patients with cardiovascular comorbidities or risk factors that predispose to worse outcomes. Consequently, the aim of this review is to identify cardiovascular prognostic factors associated with morbidity and mortality in COVID-19 and to highlight considerations for incorporating laboratory testing of biomarkers of cardiovascular performance in COVID-19 to optimise outcomes.</text>
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                <text>2020</text>
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                <text>Cardiovascular disease, coronavirus, SARS-CoV-2, COVID-19</text>
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                <text>DOI: 10.3390/v12050527</text>
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                <text>Viruses</text>
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                <text>MDPI AG</text>
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                <text>Microbiology</text>
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                  <text>Dominio científico: Coronavirus</text>
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            <name>Title</name>
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                <text>La situación de la enfermería en el mundo y la Región de las Américas en tiempos de la pandemia de COVID-19</text>
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            <description>An entity primarily responsible for making the resource</description>
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                <text>Marina Peduzzi, Silvia Helena De Bortoli Cassiani, Edgar Fernando Munar Jimenez, Augusto Umpiérrez Ferreira, Claudia Leija Hernández</text>
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                <text>2020</text>
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                <text>DOI: 10.26633/RPSP.2020.64</text>
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                <text>Revista Panamericana de Salud Pública</text>
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            <description>An entity responsible for making the resource available</description>
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                <text>Pan American Health Organization</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Arctic medicine. Tropical medicine, Public aspects of medicine, Medicine</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>SARS-CoV-2 Inflammatory Syndrome. Clinical Features and Rationale for Immunological Treatment</text>
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                <text>Vito Racanelli, Marcella Prete, Elvira Favoino, Giacomo Catacchio, Federico Perosa</text>
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            <description>An account of the resource</description>
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                <text>The current pandemic coronavirus, SARS-CoV-2, is a global health emergency because of its highly contagious nature, the great number of patients requiring intensive care therapy, and the high fatality rate. In the absence of specific antiviral drugs, passive prophylaxis, or a vaccine, the treatment aim in these patients is to prevent the potent virus-induced inflammatory stimuli from leading to the acute respiratory distress syndrome (ARDS), which has a severe prognosis. Here, the mechanism of action and the rationale for employing immunological strategies, which range from traditional chemically synthesized drugs, anti-cytokine antibodies, human immunoglobulin for intravenous use, to vaccines, are reviewed.</text>
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                <text>2020</text>
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                <text>inflammation, anti-cytokine antibodies, acute respiratory syndrome, SARS-CoV-2, COVID-19, human immunoglobulin for intravenous use</text>
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                <text>DOI: 10.3390/ijms21093377</text>
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                <text>International Journal of Molecular Sciences</text>
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                <text>MDPI AG</text>
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                <text>Biology (General), Chemistry</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>MERS-CoV Spike Protein Vaccine and Inactivated Influenza Vaccine Formulated with Single Strand RNA Adjuvant Induce T-Cell Activation through Intranasal Immunization in Mice</text>
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                <text>Hye-Jung Kim, Kyungwon Kang, Hyo Jung Park, Sang-Myeong Lee, Jaeyong Kim, Hyeong-jun Park, Yu-Sun Lee, Jae-Hwan Nam, Hye-Won Kwak, Yoo-Jin Bang, Kyung-Ah Hwang</text>
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            <description>An account of the resource</description>
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                <text>The effectiveness of vaccines is enhanced by adding adjuvants. Furthermore, the selection of an inoculation route depends on the type of adjuvant used and is important for achieving optimum vaccine efficacy. We investigated the immunological differences between two types of vaccines—spike protein from the Middle East respiratory syndrome virus and inactivated influenza virus vaccine, in combination with a single-stranded RNA adjuvant—administered through various routes (intramuscular, intradermal, and intranasal) to BALB/c mice. Intramuscular immunization with the RNA adjuvant-formulated spike protein elicited the highest humoral immune response, characterized by IgG1 and neutralizing antibody production. Although intranasal immunization did not elicit a humoral response, it showed extensive T-cell activation through large-scale induction of interferon-γ- and interleukin-2-secreting cells, as well as CD4+ T-cell activation in mouse splenocytes. Moreover, only intranasal immunization induced IgA production. When immunized with the inactivated influenza vaccine, administration of the RNA adjuvant via all routes led to protection after viral challenge, regardless of the presence of a vaccine-specific antibody. Therefore, the inoculation route should depend on the type of immune response needed; i.e., the intramuscular route is suitable for eliciting a humoral immune response, whereas the intranasal route is useful for T-cell activation and IgA induction.</text>
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                <text>2020</text>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>inactivated vaccine, Intranasal immunization, intramuscular immunization, RNA adjuvant, protein-based vaccine, Middle East respiratory syndrome coronavirus (MERS-CoA)</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="30749">
                <text>DOI: 10.3390/pharmaceutics12050441</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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                <text>Pharmaceutics</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>MDPI AG</text>
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            </elementTextContainer>
          </element>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="30752">
                <text>Pharmacy and materia medica</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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            <description>A name given to the resource</description>
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                <text>The epidemiological situation of COVID-19 in the Kyrgyz Republic</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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                <text>Vera S. Toigombaeva, Zuridin Sh. Nurmatov</text>
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            <name>Date</name>
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                <text>2020</text>
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                <text>DOI: 10.24969/hvt.2020.194</text>
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            <description>A related resource from which the described resource is derived</description>
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                <text>Heart Vessels and Transplantation</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="30742">
                <text>Center for Scientific Research and Development of Education.</text>
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            </elementTextContainer>
          </element>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="30743">
                <text>Diseases of the circulatory (Cardiovascular) system</text>
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  <item itemId="3307" public="1" featured="0">
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                <elementText elementTextId="1">
                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Can computed tomography be a primary tool for COVID-19 detection? Evidence appraisal through meta-analysis</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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                <text>Yen-Ta Huang, Pei-Chun Lai, Cheng Yifan, Chih-Wei Sung, Edward Pei-Chuan Huang, Chi-Hsin Chen</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2020</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>Meta-analysis, Computed tomography, specificity, Sensitivity, likelihood ratio, COVID-19</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="30733">
                <text>DOI: 10.1186/s13054-020-02908-4</text>
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            </elementTextContainer>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="30734">
                <text>Critical Care</text>
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            </elementTextContainer>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="30735">
                <text>BMC</text>
              </elementText>
            </elementTextContainer>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="30736">
                <text>Medical emergencies. Critical care. Intensive care. First aid</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="30720">
                <text>Developing a system of anti-crisis measures for Ukraine’s economy in the spread of the coronavirus pandemic</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="30721">
                <text>Bohdan Danylyshyn, Ivan Bohdan</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>The new global financial and economic crisis is caused by the spread of the coronavirus epidemic, the reduction in aggregate supply, the escalation of trade wars, and the outflow of capital from emerging markets. This requires national macroeconomic regulatory authorities to take prudent measures to protect national economies from destabilizing externalities. Therefore, the purpose of the article is to justify and develop a priority system of stabilization policy and anti-crisis measures to counter the spread of external shocks in the national economy, stabilize it, and create conditions for its further recovery and sustainable economic growth. To achieve this aim, the existing theoretical sources and research materials of international organizations were systematized, the legislative and regulatory framework in Ukraine was generalized, and statistical methods, a historical method, analysis and generalization were also used. As a result, the channels of impact of external shocks on Ukraine’s economy were identified, and the areas of internal vulnerability of the national economy that could significantly increase the negative effects of externalities were determined. The knowledge gained has become the basis for formulating conceptual directions of crisis management and developing a system of measures to counteract crisis phenomena, which include the monetary policy tools of the National Bank of Ukraine, the structural and fiscal policy of the Government, as well as the banking regulation and capital control policies.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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              <elementText elementTextId="30723">
                <text>2020</text>
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            </elementTextContainer>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="30724">
                <text>Economic crisis, monetary policy, stabilization policy, fiscal incentives</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="30725">
                <text>DOI: 10.21511/bbs.15(2).2020.01</text>
              </elementText>
            </elementTextContainer>
          </element>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="30726">
                <text>Banks and Bank Systems</text>
              </elementText>
            </elementTextContainer>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="30727">
                <text>LLC CPC "Business Perspectives""</text>
              </elementText>
            </elementTextContainer>
          </element>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="30728">
                <text>Banking</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="30711">
                <text>Trends of air transportation market development in Ukraine</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="30712">
                <text>Tetiana SHKODA, Oleksandr Savych</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="30713">
                <text>To identify the trends of air transportation market development in Ukraine during the period 2010–2018, the analysis of the riskiness of the external market environment of airlines being the major market actors and main factors, which influence the air transportation market development, were made in the paper using statistical methods and methods of probability theory. The working hypothesis was proved on corresponding the main trends of air transportation market development in Ukraine with the world ones and the very high riskiness of the external environment of the airlines. There is some local specifics of the air transportation market in Ukraine connected with the armed conflict at the East of the country, a significant impact of non-economic factors in some years, and implementation of international safety standards. The COVID-19 impact is considered only as a discussion question. The originality of the paper is in discussing the modern trends of air transportation market development in Ukraine in the context of considering the interaction “subject – poly-subject environment”. The airlines are considered as the subjects that interact with a market as an external poly-subject environment. The results of the research identified that the riskiness of the external market environment is at the critical level for the majority of the studied airlines that does not contribute to successful business activity in Ukraine. European and Ukrainian official authorities can use the obtained results during the development and implementation of the joined cooperation in the sphere of air transportation. Besides, in the context of COVID-19, the trends of imroving aviation safety and satisfying international standards are becoming increasingly important for airlines as well as for state authorities in developing the appropriate state policy.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="30714">
                <text>2020</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="30715">
                <text>market, development, Ukraine, Air Transportation, External environment</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="30716">
                <text>DOI: 10.21511/im.16(2).2020.03</text>
              </elementText>
            </elementTextContainer>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="30717">
                <text>Innovative Marketing</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="30718">
                <text>LLC CPC "Business Perspectives""</text>
              </elementText>
            </elementTextContainer>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="30719">
                <text>Marketing. Distribution of products</text>
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    <fileContainer>
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        <src>https://www.socictopen.socict.org/files/original/8b09c2a891429f96ee77da2ae6208ceb.pdf</src>
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          <name>Dublin Core</name>
          <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                <elementText elementTextId="1">
                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
                </elementText>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="30702">
                <text>Can Teledentistry Improve the Monitoring of Patients during the Covid-19 Dissemination? A Descriptive Pilot Study</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="30703">
                <text>Alessandro Antonelli, Amerigo Giudice, Leonzio Fortunato, Fiorella Averta, Selene Barone, Federica Diodati, Danila Muraca</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="30704">
                <text>The aim of this pilot study was to describe the advantages of telemedicine (TM) in dental practice during the current national emergency condition due to the Covid-19 dissemination. At Department of Oral Surgery and Pathology—Magna Graecia University of Catanzaro, regional reference center for Covid-19—two groups of patients were determined: patients with urgent conditions (group U) and patients in follow-up (group F). Both groups were instructed to implement remote consultations using a messaging service (WhatsApp Messenger, WhatsApp Inc., Mountain View, California, USA) to send photos. A total of 418 photos were collected by 57 patients. Thirty-four photos were obtained by five patients in the U group after surgical procedures. All patients sent photos on the established evening, except for two patients who sent two photos outside the set days. In the F group, 384 photos were collected by 52 patients. None of them sent more photos than the number that was established by the protocol. Telemedicine allowed a monitoring of all patients, reducing costs and limiting human contact, decreasing the risk of Covid-19 dissemination.</text>
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          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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              <elementText elementTextId="30705">
                <text>2020</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="30706">
                <text>dentistry, telemedicine, WhatsApp, teledentistry, dental public health, COVID-19</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="30707">
                <text>DOI: 10.3390/ijerph17103399</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="30708">
                <text>International Journal of Environmental Research and Public Health</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>MDPI AG</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="30710">
                <text>Medicine</text>
              </elementText>
            </elementTextContainer>
          </element>
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