1995 10 20655 https://www.socictopen.socict.org/files/original/9c799ce59530f283de3bb216f0901217.pdf c568ca7a009f44ec98f4480537ab3801 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource US Federal Travel Restrictions for Persons with Higher-Risk Exposures to Communicable Diseases of Public Health Concern Creator An entity primarily responsible for making the resource Laura A. Vonnahme, M. Robynne Jungerman, Reena K. Gulati, Petra Illig, Francisco Alvarado-Ramy Description An account of the resource Published guidance recommends controlled movement for persons with higher-risk exposures (HREs) to communicable diseases of public health concern; US federal public health travel restrictions (PHTRs) might be implemented to enforce these measures. We describe persons eligible for and placed on PHTRs because of HREs during 2014–2016. There were 160 persons placed on PHTRs: 142 (89%) involved exposure to Ebola virus, 16 (10%) to Lassa fever virus, and 2 (1%) to Middle East respiratory syndrome coronavirus. Most (90%) HREs were related to an epidemic. No persons attempted to travel; all persons had PHTRs lifted after completion of a maximum disease-specific incubation period or a revised exposure risk classification. PHTR enforced controlled movement and removed risk for disease transmission among travelers who had contacts who refused to comply with public health recommendations. PHTRs are mechanisms to mitigate spread of communicable diseases and might be critical in enhancing health security during epidemics. Date A point or period of time associated with an event in the lifecycle of the resource 2017 Subject The topic of the resource travel, Restrictions, public health travel restrictions, Global Health Security, Communicable diseases, epidemics Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid2313.170386 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/2280fcc62ffc1cea187ef3160c6b3cf2.pdf 7bcd15fa788bfedb04a7e9c7aa6ca941 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource US Federal Travel Restrictions for Persons with Higher-Risk Exposures to Communicable Diseases of Public Health Concern Creator An entity primarily responsible for making the resource Laura A. Vonnahme, M. Robynne Jungerman, Reena K. Gulati, Petra Illig, Francisco Alvarado-Ramy Description An account of the resource Published guidance recommends controlled movement for persons with higher-risk exposures (HREs) to communicable diseases of public health concern; US federal public health travel restrictions (PHTRs) might be implemented to enforce these measures. We describe persons eligible for and placed on PHTRs because of HREs during 2014–2016. There were 160 persons placed on PHTRs: 142 (89%) involved exposure to Ebola virus, 16 (10%) to Lassa fever virus, and 2 (1%) to Middle East respiratory syndrome coronavirus. Most (90%) HREs were related to an epidemic. No persons attempted to travel; all persons had PHTRs lifted after completion of a maximum disease-specific incubation period or a revised exposure risk classification. PHTR enforced controlled movement and removed risk for disease transmission among travelers who had contacts who refused to comply with public health recommendations. PHTRs are mechanisms to mitigate spread of communicable diseases and might be critical in enhancing health security during epidemics. Date A point or period of time associated with an event in the lifecycle of the resource 2017 Subject The topic of the resource travel, Restrictions, public health travel restrictions, Global Health Security, Communicable diseases, epidemics Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid2313.170386 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/8fad3231ab3d7d31e2508465a4cbbb79.pdf 0bb2587be5799655b9f27eb5088a0e11 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource US-county level variation in intersecting individual, household and community characteristics relevant to COVID-19 and planning an equitable response: a cross-sectional analysis Creator An entity primarily responsible for making the resource Mathew V Kiang, Caroline O Buckee, Jarvis T Chen, Taylor Chin, Rebecca Kahn, Ruoran Li, Satchit Balsari Description An account of the resource Objectives To illustrate the intersections of, and intercounty variation in, individual, household and community factors that influence the impact of COVID-19 on US counties and their ability to respond.Design We identified key individual, household and community characteristics influencing COVID-19 risks of infection and survival, guided by international experiences and consideration of epidemiological parameters of importance. Using publicly available data, we developed an open-access online tool that allows county-specific querying and mapping of risk factors. As an illustrative example, we assess the pairwise intersections of age (individual level), poverty (household level) and prevalence of group homes (community-level) in US counties. We also examine how these factors intersect with the proportion of the population that is people of colour (ie, not non-Hispanic white), a metric that reflects histories of US race relations. We defined ‘high’ risk counties as those above the 75th percentile. This threshold can be changed using the online tool.Setting US counties.Participants Analyses are based on publicly available county-level data from the Area Health Resources Files, American Community Survey, Centers for Disease Control and Prevention Atlas file, National Center for Health Statistic and RWJF Community Health Rankings.Results Our findings demonstrate significant intercounty variation in the distribution of individual, household and community characteristics that affect risks of infection, severe disease or mortality from COVID-19. About 9% of counties, affecting 10 million residents, are in higher risk categories for both age and group quarters. About 14% of counties, affecting 31 million residents, have both high levels of poverty and a high proportion of people of colour.Conclusion Federal and state governments will benefit from recognising high intrastate, intercounty variation in population risks and response capacity. Equitable responses to the pandemic require strategies to protect those in counties at highest risk of adverse COVID-19 outcomes and their social and economic impacts. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.1136/bmjopen-2020-039886 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine https://www.socictopen.socict.org/files/original/b54f633acdaf14c95f3df6af1aff8012.pdf fbb384a2ad7e416b243df383146d8444 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource USA stockpiling of remdesivir: How should the world respond? Creator An entity primarily responsible for making the resource Dalia Dawoud, Kalipso Chalkidou, Richard Sullivan, Francis J Ruiz, Amanda Adler Description An account of the resource The race to find an effective treatment for coronavirus disease 2019 (COVID-19) is still on, with only two treatment options currently authorized for emergency use and/or recommended for patients hospitalized with severe respiratory symptoms: low-dose dexamethasone and remdesivir. The USA decision to stockpile the latter has resulted in widespread condemnation and in similar action being taken by some other countries. In this commentary we discuss whether stockpiling remdesivir is justified in light of the currently available evidence. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource coronavirus, antiviral, covid-19, SARS-CoV-2, Remdesivir, Dexamethasone, stockpiling Identifier An unambiguous reference to the resource within a given context 10.2217/cer-2020-0174 Source A related resource from which the described resource is derived Journal of comparative effectiveness research https://www.socictopen.socict.org/files/original/2c5a128b0ddb9cb19d5907889cbd35ed.pdf ebd823bb2ae7ee05a0dfa9c3eb4b3d00 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Usage of the Heterologous Expression of the Antimicrobial Gene afp From Aspergillus giganteus for Increasing Fungal Resistance in Olive Creator An entity primarily responsible for making the resource Isabel Narvaez, Titouh Khayreddine, Clara Pliego, Sergio Cerezo, Rafael M. Jiménez-Díaz, Rafael M. Jiménez-Díaz, José L. Trapero-Casas, Carlos López-Herrera, Isabel Arjona-Girona, Carmen Martín, José A. Mercado, Fernando Pliego-Alfaro Description An account of the resource The antifungal protein (AFP) produced by Aspergillus giganteus, encoded by the afp gene, has been used to confer resistance against a broad range of fungal pathogens in several crops. In this research, transgenic olive plants expressing the afp gene under the control of the constitutive promoter CaMV35S were generated and their disease response against two root infecting fungal pathogens, Verticillium dahliae and Rosellinia necatrix, was evaluated. Embryogenic cultures derived from a mature zygotic embryo of cv. ‘Picual’ were used for A. tumefaciens transformation. Five independent transgenic lines were obtained, showing a variable level of afp expression in leaves and roots. None of these transgenic lines showed enhanced resistance to Verticillium wilt. However, some of the lines displayed a degree of incomplete resistance to white root rot caused by R. necatrix compared with disease reaction of non-transformed plants or transgenic plants expressing only the GUS gene. The level of resistance to this pathogen correlated with that of the afp expression in root and leaves. Our results indicate that the afp gene can be useful for enhanced partial resistance to R. necatrix in olive, but this gene does not protect against V. dahliae. Date A point or period of time associated with an event in the lifecycle of the resource 2018 Subject The topic of the resource Fungal Resistance, Olea europaea, Rosellinia necatrix, Verticillium dahliae, transgenic plants, verticillium wilt Identifier An unambiguous reference to the resource within a given context 10.3389/fpls.2018.00680 Source A related resource from which the described resource is derived Frontiers in Plant Science Publisher An entity responsible for making the resource available Frontiers Media S.A. Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Plant culture Relation A related resource <a href="https://www.frontiersin.org/article/10.3389/fpls.2018.00680/full" target="_blank" rel="noreferrer noopener">https://www.frontiersin.org/article/10.3389/fpls.2018.00680/full</a> https://www.socictopen.socict.org/files/original/e0b190fba91baa85da27d51f3185d642.pdf 16307fb8707bcf4a7bb3d9f74f1a262f Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Use of a Copper- and Zinc-Modified Natural Zeolite to Improve Ethylene Removal and Postharvest Quality of Tomato Fruit Creator An entity primarily responsible for making the resource Johannes de Bruijn, Ambar Gómez, Cristina Loyola, Pedro Melín, Víctor Solar, Norberto Abreu, Federico Azzolina-Jury, Héctor Valdés Description An account of the resource Ethylene stimulates ripening and senescence by promoting chlorophyll loss, red pigment synthesis, and softening of tomatoes and diminishes their shelf-life. The aim of this work was to study the performance of a novel copper- and zinc-based ethylene scavenger supported by ion-exchange on a naturally occurring zeolite by analyzing its ethylene adsorption capacity and the influence of ethylene scavenging on quality attributes during the postharvest life of tomatoes. The influence of copper- and zinc-modified zeolites on ethylene and carbon dioxide concentrations and postharvest quality of tomatoes was compared with unmodified zeolite. Interactions among ethylene molecules and zeolite surface were studied by diffuse reflectance infrared Fourier transform spectroscopy in operando mode. The percentage of ethylene removal after eight days of storage was 57% and 37% for the modified zeolite and pristine zeolite, respectively. The major ethylene increase appeared at 9.5 days for the modified zeolite treatment. Additionally, modified zeolite delayed carbon dioxide formation by six days. Zeolite modified with copper and zinc cations favors ethylene removal and delays tomato fruit ripening. However, the single use of unmodified zeolite should be reconsidered due to its ripening promoting effects in tomatoes at high moisture storage conditions, as water molecules block active sites for ethylene adsorption. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource DRIFTS <i>operando</i>, Post-harvest quality, Tomato, Zeolite, adsorption, ethylene scavenging Identifier An unambiguous reference to the resource within a given context 10.3390/cryst10060471 Source A related resource from which the described resource is derived Crystals Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Crystallography Relation A related resource <a href="https://www.mdpi.com/2073-4352/10/6/471" target="_blank" rel="noreferrer noopener">https://www.mdpi.com/2073-4352/10/6/471</a> https://www.socictopen.socict.org/files/original/36f0b2cc6a6b3959deb4acf4d46eb6c3.pdf 47f70083e21ac56afca151084893a8c2 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource USE OF ALTERNATIVE SUBSTRATES FOR BROCCOLI SEEDLING PRODUCTION UNDER GREENHOUSE CONDITIONS Creator An entity primarily responsible for making the resource José Hernán Zurita-Vasquez, Edgar Luciano Valle-Velastegui, Marcia Eduviges Buenaño-Sanchez, Deysi Alexadra Guevara-Freire, Gonzalo Javier Mena-Viera, Carlos Luis Vasquez-Freitez Description An account of the resource In this study, the effect of two alternative growing substrates (corncob and Azolla anabaena) on some vegetative parameters (days to emergence, stem diameter, plant height and root volume) in seedlings of broccoli hybrid Coronado were evaluated. Both materials were ground and used according to the following treatments: 100% corncob (T1), 100% Azolla (T2), 50% corncob + Azolla 50% (T3), corncob 75% + Azolla 25% (T4), 25% corncob + Azolla 75% (T5) and then compared to a commercial substrate (BM2) (T6). Substrates were uniformly mixed, deposited in germination trays and watered at field capacity. Additionally, physic-chemical characteristics were determined in the different substrates used for broccoli seedling production. Stem diameter, height plant and root volume showed to be statistically higher in seedlings grown in commercial substrate (0.18 cm, 5.27 cm and 0.61 cm3, respectively) followed by those seedlings grown in 100% Azolla (0.17 cm, 4.92 cm and 0.49 cm3, respectively) (p< 0.001). Seedlings growing in substrates with higher corncob proportion showed lower values in these vegetative parameters. Based on our results, Azolla showed potential to be used as a seed substrate for production of broccoli seedlings, thus decreasing the use of peat and consequently the production costs in nurseries. Date A point or period of time associated with an event in the lifecycle of the resource 2018 Subject The topic of the resource Agricultura orgânica, Azolla, Brassica, residuos de maíz, sustratos Source A related resource from which the described resource is derived Tropical and Subtropical Agroecosystems Publisher An entity responsible for making the resource available Universidad Autónoma de Yucatán Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Agriculture (General), Agriculture Relation A related resource <a href="https://www.revista.ccba.uady.mx/ojs/index.php/TSA/article/view/2580" target="_blank" rel="noreferrer noopener">https://www.revista.ccba.uady.mx/ojs/index.php/TSA/article/view/2580</a> https://www.socictopen.socict.org/files/original/a1cd7e8e52cccd5f892f0857af2ea70d.pdf 6ec2d43b021e357563788fdc4eae19c0 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Use of an Innovative Web-Based Laboratory Surveillance Platform to Analyze Mixed Infections Between Human Metapneumovirus (hMPV) and Other Respiratory Viruses Circulating in Alberta (AB), Canada (2009–2012) Creator An entity primarily responsible for making the resource Shamir Mukhi, Sumana Fathima, Jennifer May-Hadford, Bonita E Lee, Steven J. Drews Description An account of the resource We investigated the proportions of mono vs. mixed infections for human metapneumovirus (hMPV) as compared to adenovirus (ADV), four types of coronavirus (CRV), parainfluenza virus (PIV), RSV, and enterovirus/rhinovirus (ERV) in Alberta, Canada. Using the Data Integration for Alberta Laboratories (DIAL) platform, 26,226 respiratory specimens at ProvLab between 1 July 2009 and 30 June 2012 were selected and included in the study. Using the Respiratory Virus Panel these specimens tested positive for one or more respiratory virus and negative for influenza A and B. From our subset hMPV was the fourth most common virus (n=2,561) with 373 (15%) identified as mixed infection using DIAL. Mixed infection with hMPV was most commonly found in infants less than 6 months old and ERV was most commonly found in mixed infection with hMPV (230/373, 56%) across all age groups. The proportion of mixed-infection vs. mono-infection was highest for ADV (46%), followed by CRV 229E (32%), CRV HKU1 (31%), CRV NL63 (28%), CRV OC43 (23%), PIV (20%), RSV (17%), hMPV (15%) and ERV (13%). hMPV was significantly more likely to be identified in mono infection as compared with ADV, CRV, PIV, and RSV with the exception of ERV [p &lt; 0.05]. Date A point or period of time associated with an event in the lifecycle of the resource 2012 Subject The topic of the resource hMPV, co-infection, Testing, Epidemiology, respiratory Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/v4112754 Source A related resource from which the described resource is derived Viruses Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology Language A language of the resource EN https://www.socictopen.socict.org/files/original/7ce598cb8ea325a6d7108ea38675c065.pdf 24d028c4d09ed01be7845eb9b414369d Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Use of Anti-Cytokine Therapy in Kidney Transplant Recipients with COVID-19 Creator An entity primarily responsible for making the resource Marta Bodro, Frederic Cofan, Jose Ríos, Sabina Herrera, Laura Linares, María Angeles Marcos, Alex Soriano, Asunción Moreno, Fritz Diekmann Description An account of the resource In the context of the coronavirus disease 2019 (COVID-19) pandemic, we aimed to evaluate the impact of anti-cytokine therapies (AT) in kidney transplant recipients requiring hospitalization due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. This is an observational retrospective study, which included patients from March to May 2020. An inverse probability of treatment weighting from a propensity score to receive AT was used in all statistical analyses, and we applied a bootstrap procedure in order to calculate an estimation of the 2.5th and 97.5th percentiles of odds ratio (OR). outcomes were measured using an ordinal scale determination (OSD). A total of 33 kidney recipients required hospitalization and 54% of them received at least one AT, mainly tocilizumab (42%), followed by anakinra (12%). There was no statistical effect in terms of intensive care unit (ICU) admission, respiratory secondary infections (35% vs. 7%) or mortality (16% vs. 13%) comparing patients that received AT with those who did not. Nevertheless, patients who received AT presented better outcomes during hospitalization in terms of OSD ≥5 ((OR 0.31; 2.5th, 97.5th percentiles (0.10; 0.72)). These analyses indicate, as a plausible hypothesis, that the use of AT in kidney transplant recipients presenting with COVID-19 could be beneficial, even though multicenter randomized control trials using these therapies in transplanted patients are needed. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource mortality, covid-19, infection, kidney transplantation, Anti-cytokine therapy Identifier An unambiguous reference to the resource within a given context 10.3390/jcm10081551 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine https://www.socictopen.socict.org/files/original/8f40d94c24057135e0f89477a8962fe1.pdf 642582be898b1c7cbf09aeae48ccae5c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Use of Aptamers as Diagnostics Tools and Antiviral Agents for Human Viruses Creator An entity primarily responsible for making the resource Víctor M González, M Elena Martín, Gerónimo Fernández, Ana García-Sacristán Description An account of the resource Appropriate diagnosis is the key factor for treatment of viral diseases. Time is the most important factor in rapidly developing and epidemiologically dangerous diseases, such as influenza, Ebola and SARS. Chronic viral diseases such as HIV-1 or HCV are asymptomatic or oligosymptomatic and the therapeutic success mainly depends on early detection of the infective agent. Over the last years, aptamer technology has been used in a wide range of diagnostic and therapeutic applications and, concretely, several strategies are currently being explored using aptamers against virus proteins. From a diagnostics point of view, aptamers are being designed as a bio-recognition element in diagnostic systems to detect viral proteins either in the blood (serum or plasma) or into infected cells. Another potential use of aptamers is for therapeutics of viral infections, interfering in the interaction between the virus and the host using aptamers targeting host-cell matrix receptors, or attacking the virus intracellularly, targeting proteins implicated in the viral replication cycle. In this paper, we review how aptamers working against viral proteins are discovered, with a focus on recent advances that improve the aptamers’ properties as a real tool for viral infection detection and treatment. Date A point or period of time associated with an event in the lifecycle of the resource 2016 Subject The topic of the resource aptamer, diagnosis, Ebola, HBV, HCV, HIV, influenza, SELEX, therapeutic, virus Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/ph9040078 Source A related resource from which the described resource is derived Pharmaceuticals Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Pharmacy and materia medica Language A language of the resource EN