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                <text>COVID-19 and Labour Law: Ukraine</text>
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                <text>Yana Simutina, Sergii Venediktov</text>
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                <text>The most important reaction of Ukrainian legislation associated with COVID-19 is the amendments made to the Labour Code regarding remote work and flexible working hours. Due to the fact that many enterprises during national quarantine have reduced their activities or are not working at all, in such cases downtime should be paid at the rate of not less than two-thirds of the salary set for the employee. Only upon their consent employees can be provided with unpaid leave, which is limited by the quarantine time frames. E mployers are eligible to receive the partial unemployment benefit from the state for the quarantine period in the amount of 2/3 of wages in order to pay their employees for preserving the employment relationship.</text>
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                <text>covid-19, Labour Law, remote work, unpaid leave, flexible working hours, Downtime, partial unemployment benefit</text>
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                <text>10.6092/issn.1561-8048/10946</text>
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                <text>Epidemiology and Health</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Law in general. Comparative and uniform law. Jurisprudence, Labor. Work. Working class</text>
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                  <text>Agricultura sostenible</text>
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                <text>Perspectivas del uso de bacterias rizosféricas en el control de Pyricularia grisea (Cooke Sacc.) en el cultivo del arroz (Oryza sativa L.)</text>
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                <text>Yanelis Acebo Guerrero, Annia Hernández-Rodríguez, Narovis Rives Rodríguez, Ana Niurka Hernández-Lauzardo</text>
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                <text>Prospect of the use of bacteria in the control Pyricularia grisea (Cooke Sacc.) on rice (Oriza sativa L.)   Título corto: Bacterias rizosféricas para controlar la piriculariosis   Resumen El arroz es fuente de alimento para una gran parte de la población mundial, con alto promedio de consumo anual. En este cultivo las enfermedades de origen microbiano constituyen uno de los factores que inciden en la obtención de bajos rendimientos y calidad de los granos. La piriculariosis o añublo del arroz, causada por Pyricularia grisea, es la enfermedad más importante en este cultivo en América Latina, ya que puede provocar hasta el 100% de reducción de los rendimientos. Como parte de la estrategia de agricultura sostenible, se trata de controlar estos patógenos y lograr altos rendimientos del cultivo mediante una combinación adecuada de fertilizantes químicos y productos biológicos. En este sentido, la aplicación de inoculantes bacterianos constituidos por bacterias promotoras del crecimiento vegetal (Plant Growth- Promoting Bacteria, PGPB, por sus siglas en inglés) ha constituido una alternativa ecológica que favorece la conservación del medioambiente y el ecosistema. Este trabajo tiene como objetivo abordar el estado actual y las perspectivas de uso de bacterias rizosféricas en el control de Pyricularia grisea en el cultivo del arroz, tratando algunos temas relevantes, como son las principales enfermedades que afectan al cultivo, los géneros de PGPB más utilizados para el control de las mismas y sus principales mecanismos de acción.  Palabras clave: bacterias rizosféricas, arroz, piriculariosis.   Abstract Rice is an important food supply for a large part of the world population and its consumption rates are very high. Microbial diseases are one of the main causes that provoke low yields and low-quality spotted grains. Although fungi, bacteria and viruses are mostly the responsible for these losses, fungal diseases strike more frequently.  Among fungi, Pyricularia grisea, the blast fungus is responsible for up to 100% of reduction in yields, being the blast the most important rice disease in Latin America. To control this pathogen, a strategy of sustainable agriculture might be developed, combining accurately chemical and biological products. PGPB based bioproducts have been considered as an eco-friendly alternative, which favours environment preservation. This work was aimed to approach the current status and outlook of the use of rhizobacteria in the biocontrol of Pyricularia grisea on rice. Main diseases attacking rice, most beneficial PGPB and its mechanisms of action will be discussed too in this review. Key words: Plant growth promoting bacteria, rice, biological control, blast fungus.</text>
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                <text>2011</text>
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                <text>Bacterias rizosféricas, Plant growth promoting bacteria, arroz, biological control, blast fungus, piriculariosis, rice</text>
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                <text>Revista Colombiana de Biotecnología</text>
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                <text>Universidad Nacional de Colombia</text>
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                <text>Biotechnology</text>
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                <text>&lt;a href="https://revistas.unal.edu.co/index.php/biotecnologia/article/view/22920" target="_blank" rel="noreferrer noopener"&gt;https://revistas.unal.edu.co/index.php/biotecnologia/article/view/22920&lt;/a&gt;</text>
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                  <text>Agricultura sostenible</text>
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                  <text>Dominio científico: Agricultura sostenible</text>
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                <text>Estudio de la distribución de los primates en Colombia basado en un análisis por parsimonia de endemismos (PAE)</text>
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                <text>Yaneth Muñoz Saba, Paula Martínez Silva</text>
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                <text>Colombia es el quinto país con el mayor número de especies de primates Platirhinos a nivel mundial, presentando doce de los dieciséis géneros existentes, distribuidos desde el nivel del mar hasta 3.200 metros de altura. Probablemente debido a esto, los primates son el grupo de mamíferos mejor conocido en nuestro país, existiendo una amplia gama de estudios publicados en cuanto a distribución, comportamiento y ecología; sin embargo, aún es mucho lo que falta por descubrir y aclarar en cuanto a su taxonomía e historia natural. La distribución de los primates en el territorio colombiano, obedece en general a una serie de fenómenos geológicos históricos como el surgimiento de la cordillera de Los Andes, las regresiones y trasgresiones marinas y la formación de refugios húmedos y secos durante el período Pleistoceno, entre otros. En este trabajo se hizo un Análisis por Parsimonia de Endemismos (PAE) basado en la recolección de datos actuales de presencia ausencia de primates en Colombia para identificar regiones de riqueza y endemismo de especies, relacionar éstas regiones con los fenómenos históricos geológicos mencionados anteriormente y proponer una nueva reorganización de regiones geográficas para Colombia. Se propone una reorganización en nueve regiones biogeográficas, un dendrograma que relaciona los distritos biogeográficos del país y una serie de hipótesis sobre los posibles patrones de dispersión geográfica que se han presentado al interior de los primates desde su arribo al continente americano.</text>
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                <text>2004</text>
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                <text>Análisis por Parsimonia de Endemismos, Primates Platirhinos</text>
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                <text>Acta Biológica Colombiana</text>
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                <text>Universidad Nacional de Colombia</text>
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                <text>Biology (General)</text>
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                <text>Prevention and control of patients in surgical wards of local hospitals facing COVID-19.</text>
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                <text>Yang Chuang, Wang Jisheng, Qiao Tianyu, He Jingyu</text>
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                <text>2021</text>
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                <text>10.1016/j.asjsur.2020.10.014</text>
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                <text>Asian journal of surgery</text>
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          <element elementId="50">
            <name>Title</name>
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                <text>Association of SARS susceptibility with single nucleic acid polymorphisms of OAS1 and MxA genes: a case-control study</text>
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          <element elementId="39">
            <name>Creator</name>
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                <text>Yang Hong, Zhan Lin, Tang Fang, Plancoulaine Sabine, Zhang Pan-He, Fontanet Arnaud, Wang Hongwei, de Vlas Sake J, Feng Dan, He Jing, Wang Tianbao, Richardus Jan H, Habbema J Dik F, Cao Wu-Chun</text>
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                <text>Abstract Background Host genetic factors may play a role in susceptibility and resistance to SARS associated coronavirus (SARS-CoV) infection. The study was carried out to investigate the association between the genetic polymorphisms of 2',5'-oligoadenylate synthetase 1 (OAS1) gene as well as myxovirus resistance 1 (MxA) gene and susceptibility to SARS in Chinese Han population. Methods A hospital-based case-control study was conducted. A collective of 66 SARS cases and 64 close contact uninfected controls were enrolled in this study. End point real time polymerase chain reaction (PCR) and PCR-based Restriction Fragment Length Polymorphism (RFLP) analysis were used to detect the single nucleic polymorphisms (SNPs) in OAS1 and MxA genes. Information on other factors associated with SARS infection was collected using a pre-tested questionnaire. Univariate and multivariate logistic analyses were conducted. Results One polymorphism in the 3'-untranslated region (3'-UTR) of the OAS1 gene was associated with SARS infection. Compared to AA genotype, AG and GG genotypes were found associated with a protective effect on SARS infection with ORs (95% CI) of 0.42 (0.20~0.89) and 0.30 (0.09~0.97), respectively. Also, a GT genotype at position 88 in the MxA gene promoter was associated with increased susceptibility to SARS infection compared to a GG genotype (OR = 3.06, 95% CI: 1.25~7.50). The associations of AG genotype in OAS1 and GT genotype in MxA remained significant in multivariate analyses after adjusting for SARS protective measures (OR = 0.38, 95% CI: 0.14~0.98 and OR = 3.22, 95% CI: 1.13~9.18, respectively). Conclusion SNPs in the OAS1 3'-UTR and MxA promoter region appear associated with host susceptibility to SARS in Chinese Han population.</text>
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                <text>2006</text>
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                <text>DOI: 10.1186/1471-2334-6-106</text>
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                <text>BMC Infectious Diseases</text>
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                <text>Infectious and parasitic diseases</text>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Neutralizing antibodies against SARS-CoV-2: current understanding, challenge and perspective.</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="60377">
                <text>Yang Huang, Hui Sun, Hai Yu, Shaowei Li, Qingbing Zheng, Ningshao Xia</text>
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          <element elementId="41">
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            <description>An account of the resource</description>
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              <elementText elementTextId="60378">
                <text>The rapid emergence of Coronavirus disease-2019 (COVID-19) caused by severe acute respiratory syndrome 2 coronavirus (SARS-CoV-2) as a pandemic that presents an urgent human health crisis. Many SARS-CoV-2 neutralizing antibodies (NAbs) were developed with efficient therapeutic potential. NAbs-based therapeutics against SARS-CoV-2 are being expedited to preclinical and clinical studies with two antibody drugs, LY3819253 (LY-CoV555) and REGN-COV2 (REGN10933 and REGN10987), approved by the US Food and Drug Administration for emergency use authorization for treating COVID-19. In this review, we provide a systemic overview of SARS-CoV-2 specific or cross-reactive NAbs and discuss their structures, functions and neutralization mechanisms. We provide insight into how these NAbs specific recognize the spike protein of SARS-CoV-2 or cross-react to other CoVs. We also summarize the challenges of NAbs therapeutics such as antibody-dependent enhancement and viral escape mutations. Such evidence is urgently needed to the development of antibody therapeutic interventions that are likely required to reduce the global burden of COVID-19.</text>
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                <text>2020</text>
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                <text>spike protein, covid-19, SARS-CoV-2, neutralizing antibodies, hace2</text>
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          <element elementId="43">
            <name>Identifier</name>
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              <elementText elementTextId="60381">
                <text>10.1093/abt/tbaa028</text>
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            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="60382">
                <text>Antibody therapeutics</text>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                <elementText elementTextId="1">
                  <text>Coronavirus</text>
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            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
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              <elementText elementTextId="34407">
                <text>Characteristics of COVID-19 Clinical Trials in China Based on the Registration Data on ChiCTR and ClinicalTrials.gov</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="34408">
                <text>Yang J, He Y., Huang J, Su Q</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="34409">
                <text>Jihan Huang,1,* Yingchun He,1,* Qianmin Su,2 Juan Yang1 1Center for Drug Clinical Research, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, People&amp;rsquo;s Republic of China; 2Department of Computer in College of Electronic and Electrical Engineering, Shanghai University of Engineering Science, Shanghai 201620, People&amp;rsquo;s Republic of China*These authors contributed equally to this workCorrespondence: Jihan Huang; Juan YangCenter for Drug Clinical Research, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, #1200 Cailun Road, Pudong New District, Shanghai 201203, People&amp;rsquo;s Republic of ChinaTel +86 21 51322420Email huangjihan@shutcm.edu.cn; janeyang5006@163.comObjective: This study aimed to evaluate the fundamental characteristics of coronavirus disease (COVID-19) clinical trials registered in China.Methods: COVID-19 clinical trials registered in China were analyzed from databases on ChiCTR and ClinicalTrials.gov. The study designs, samples, primary end points, and intervention measures were evaluated.Results: In total, 262 intervention clinical trials were retrieved on March 10, 2020. Overall, 181 (69.1%) trials involved two groups, 200 (76.3%) trials were randomized parallel trials, 24 (9.2%) trials were double blind, and 60.3% of trials included &amp;le; 100 participants. Sixty (22.9%) trials considered symptom improvement as the primary endpoint and 43 (16.4%) trials considered the rate or time at which the subjects became virus-free as the primary endpoint. Of 262 intervention studies, chemical drugs and biological products were studied in 105 (40.1%) intervention studies, of which antiviral drugs accounted for 15.3% and malaria drugs accounted for 8.4% of the studies. Among all trials, 27.9% of the studies used traditional Chinese medicine (TCM), 10.3% used cell therapy, and 5.0% used plasma therapy.Conclusion: This study is the first snapshot of the landscape of COVID-19 clinical trials registered in China and provided the basic features of clinical trial designs for the treatment and prevention of COVID-19 to offer useful information to guide future clinical trials on COVID-19 in other countries.Keywords: COVID-19, clinical trial, interventional, randomized, blinding</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2020</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="34411">
                <text>clinical trial, randomized, interventional, Blinding, COVID-19</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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                <text>DOI: </text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="34413">
                <text>Drug Design, Development and Therapy</text>
              </elementText>
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          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="34414">
                <text>Dove Medical Press</text>
              </elementText>
            </elementTextContainer>
          </element>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="34415">
                <text>Therapeutics. Pharmacology</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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              </elementTextContainer>
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            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
                </elementText>
              </elementTextContainer>
            </element>
          </elementContainer>
        </elementSet>
      </elementSetContainer>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="23561">
                <text>Emergency trauma care during the outbreak of corona virus disease 2019 (COVID-19) in China</text>
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          </element>
          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="23562">
                <text>Yang Li, Fan Yang, Yu Xie, Jian-Xin Jiang, Hao Tang, Wei-Guo Zhang, Ding Liu, Lian-yang ZHANG, Qiu Zhong, Guo Liu, Ling Zeng, Hua-Yu Zhang, Shan-Mu Ai, Xiao-qing AN, Qingxiang Mao, Siru Zhou, Zhan-Fei Li, Letian Zhang, Liyong Chen, Xiang-Jun Bai, Tomer Talmy, Hua-Cai Zhang, Hongxiang Lu</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="23563">
                <text>Abstract Background A novel coronavirus pneumonia outbreak began in Wuhan, Hubei Province, in December 2019; the outbreak was caused by a novel coronavirus previously never observed in humans. China has imposed the strictest quarantine and closed management measures in history to control the spread of the disease. However, a high level of evidence to support the surgical management of potential trauma patients during the novel coronavirus outbreak is still lacking. To regulate the emergency treatment of trauma patients during the outbreak, we drafted this paper from a trauma surgeon perspective according to practical experience in Wuhan. Main body The article illustrates the general principles for the triage and evaluation of trauma patients during the outbreak of COVID-19, indications for emergency surgery, and infection prevention and control for medical personnel, providing a practical algorithm for trauma care providers during the outbreak period. Conclusions The measures of emergency trauma care that we have provided can protect the medical personnel involved in emergency care and ensure the timeliness of effective interventions during the outbreak of COVID-19.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2020</text>
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          <element elementId="49">
            <name>Subject</name>
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              <elementText elementTextId="23565">
                <text>trauma, Infection prevention, emergency surgery, novel coronavirus</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="23566">
                <text>DOI: 10.1186/s13017-020-00312-5</text>
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            </elementTextContainer>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="23567">
                <text>World Journal of Emergency Surgery</text>
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            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>BMC</text>
              </elementText>
            </elementTextContainer>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Surgery, Medical emergencies. Critical care. Intensive care. First aid</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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          <element elementId="50">
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                <text>The interpretation of Consensus on emergency surgery and infection prevention and control for severe trauma patients with 2019 novel corona virus pneumonia</text>
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            <name>Creator</name>
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            <elementTextContainer>
              <elementText elementTextId="13054">
                <text>Yang Li, Lian-yang ZHANG</text>
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                <text>A coronavirus disease 2019 (COVID-19) outbreak has occurred in Wuhan, Hubei province since Dec. 2019. As of Feb. 10, 2020, more than 40,000 cases had been confirmed, nearly 30,000 cases in Hubei alone, and no inflection point in epidemiology appeared. Severe trauma may still occur during the outbreak of the COVID-19. In order to protect the medical personnel involved in emergency treatment and ensuring the timeliness of treatment for trauma patients, The Trauma Surgery Branch of Chinese Medical Doctors' Association (CMDA) organized the drafting of the present expert consensus. This paper interprets the main views of the expert consensus, emphasizes that the safety of health care staff and patients are equally important, and that the treatment strategies and procedures for severe trauma need to be adjusted during the COVID-19 outbreak. The consensus also recommends the use of CT scan, which plays both the role of screening COVID-19 and accurate assessment of trauma, and strengthening the protection of medical staff. The consensus states that medical personnel can be exempted from isolation if they wear standard three-level protective equipment and are not accidentally exposed during the operation. This expert consensus is the first one to systematically review, summarize and analyze the progress of COVID-19 from a surgeon's perspective. It may be used as a reference for medical institutions at all levels to treat patients with severe trauma and perform other kinds of operations during the COVID-19 outbreak.  DOI: 10.11855/j.issn.0577-7402.2020.02.02</text>
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