2022 10 20655 https://www.socictopen.socict.org/files/original/7d46d0e37b6198bfc009a71927c09ba5.pdf d95df293381d7e18e5725f1a02d8c23f Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Sex-specific clinical characteristics and prognosis of coronavirus disease-19 infection in Wuhan, China: A retrospective study of 168 severe patients. Creator An entity primarily responsible for making the resource Yifan Meng, Ping Wu, Wanrong Lu, Kui Liu, Ke Ma, Liang Huang, Jiaojiao Cai, Hong Zhang, Yu Qin, Haiying Sun, Wencheng Ding, Lingli Gui, Peng Wu Description An account of the resource To confirm the relationship between sex and the progression of Coronavirus Disease-19 (COVID-19), and its potential mechanism, among severe patients. For this retrospective study, we included 168 consecutive severe patients with pathogen-confirmed COVID-19 who were hospitalized between January 16th and February 4th, 2020, at Tongji Hospital in Wuhan, China. Clinical characteristics, laboratory parameters, and outcomes were compared and analyzed between males and females. In the present study, we analyzed 168 severe patients with COVID-19, including 86 males and 82 females, and 48 patients (28.6%) were diagnosed as critically ill. Of 86 male patients, 12.8% (11/86) died and 75.6% (65/86) were discharged; of 82 female patients, 7.3% (6/82) died and 86.6% (71/82) were discharged. Eleven laboratory parameters showed significant differences between male and female patients, and six of them were higher during the whole clinical course in patients who died than in patients who were discharged. In adjusted logistic regression analysis, males with comorbidities presented a higher risk of being critically ill than males without comorbidities (OR = 3.824, 95% CI = 1.279-11.435). However, this association attenuated to null in female patients (OR = 2.992, 95% CI = 0.937-9.558). A similar sex-specific trend was observed in the relation between age and critically ill conditions. We highlighted sex-specific differences in clinical characteristics and prognosis. Male patients appeared to be more susceptible to age and comorbidities. Sex is an important biological variable that should be considered in the prevention and treatment of COVID-19. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.1371/journal.ppat.1008520 Source A related resource from which the described resource is derived PLoS Pathogens Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General), Immunologic diseases. Allergy https://www.socictopen.socict.org/files/original/ce1ae5924f7d3036520301b3c241ba12.pdf b2e2adc89b727e0e2b76457f556947e0 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Porcine epidemic diarrhea virus S1 protein is the critical inducer of apoptosis Creator An entity primarily responsible for making the resource Yifeng CHEN, Zhibang Zhang, Jie Li, Yueyi Gao, Lei Zhou, Xinna Ge, Jun Han, Xin Guo, Hanchun Yang Description An account of the resource Abstract Background Porcine Epidemic Diarrhea (PED) is an acute and highly contagious enteric disease caused by PED virus (PEDV), characterized by vomitting, watery diarrhea and fatal dehydration with high mortality in sucking piglets of one week of age. Although PEDV induced cell apoptosis has been established in vitro and in vivo, the functional protein that contributes to this event remains unclear. Methods The activation or cleavage of main apoptosis-associated molecular such as AIFM1, caspase-3, caspase-8, caspase-9 and PARP in PEDV infected host cells were analyzed by western blotting. The nuclear change of infected cell was monitored by confocal immunofluorescence assay. The overexpressing plasmids of 16 non-structural proteins (Nsp1–16) and 6 structural proteins (M, N, E, ORF3, S1 and S2) were constructed by cloning. Cell apoptosis induced by PEDV or overexpression non-structural or structural proteins was measured by the flow cytometry assay. Results PEDV could infect various host cells including Vero, Vero-E6 and Marc-145 and cause obvious cytopathic effects, including roundup, cell fusion, cell membrane vacuolation, syncytium formation and cause apparent apoptosis. In infected cells, PEDV-induced apoptosis is accompanied by nuclear concentration and fragmentation as a result of caspase-3 and caspase-8 activation and AIFM1 and PARP cleavage. Overexpression of S1 Spike protein of PEDV SM98 strain effectively induced host cell apoptosis, while the expression of the other non-structure proteins (Nsp1–16) and structural proteins (M, N, E, S2 and ORF3) has no or less effect on cell apoptosis. Similarly, expression of S1 protein from wild-type strain BJ2011 or cell-adapted strain CV777, also induce apoptosis in transfected cells. Finally, we demonstrated that the S1 proteins from various coronavirus family members such as TGEV, IBV, CCoV, SARS and MERS could also induce Vero-E6 cells apoptosis. Conclusion S1 Spike protein is one of the most critical functional proteins that contribute to cell apoptosis. Expression of S1 proteins of the coronavirus tested in this study could all induce cell apoptosis suggesting S1 maybe is an effective inducer in Coronavirus-induced cell apoptosis and targeting S1 protein expression probably is a promising strategy to inhibit coronavirus infection and thus mediated apoptosis on host cells. Date A point or period of time associated with an event in the lifecycle of the resource 2018 Subject The topic of the resource Porcine Epidemic Diarrhea Virus (PEDV), Spike S1 protein, apoptosis, Apoptosis-inducing factor mitochondria associated 1 (AIFM1) Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/s12985-018-1078-4 Source A related resource from which the described resource is derived Virology Journal Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases Language A language of the resource EN https://www.socictopen.socict.org/files/original/7ec7b738e12ebba2d8ab5f69a632cdb9.pdf a062becb5487e2cc80fa858eb3971a49 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Perceived Stress and Its Associated Factors during COVID-19 among Healthcare Providers in Ethiopia: A Cross-Sectional Study Creator An entity primarily responsible for making the resource Yigrem Ali Chekole, Solomon Yimer Minaye, Semagn Mekonnen Abate, Birhanie Mekuriaw Description An account of the resource Background. Coronavirus causes serious health problems worldwide including increased mental health burden to the society at large scale and particularly the healthcare providers. Understanding the immediate mental health and psychological response of the healthcare providers after a public health emergency is important for implementing better prevention and response mechanisms to a disaster. Objective. This study aimed to assess the prevalence of perceived stress and risk factors of coronavirus disease 2019 among healthcare providers in Dilla, Southern Ethiopia. Methods. An institution-based cross-sectional study was conducted among 244 samples selected with the systematic random sampling technique from March to April 2020. Data collection was carried out with a validated perceived stress scale adapted from the World Health Organization. Data were coded and entered into Epi Info Version 7 and were exported and analyzed with SPSS version 20. Crude and adjusted OR were analyzed using logistic regression, and the level of significance of association was determined at P value Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.1155/2020/5036861 Source A related resource from which the described resource is derived Advances in Public Health Publisher An entity responsible for making the resource available Hindawi Limited Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Public aspects of medicine https://www.socictopen.socict.org/files/original/3b29a933f0c36ce81a6bc74bcb19f1e4.pdf d696ee4047aea713428a29c56f111d47 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Experimental Study on Bluff-Body Stabilized Premixed Flame with a Central Air/Fuel Jet Creator An entity primarily responsible for making the resource Yiheng Tong, Shuang Chen, Mao Li, Zhongshan Li, Jens Klingmann Description An account of the resource Bluff-body flame holders are commonly employed in many industrial applications. A bluff-body is usually adopted to enhance the downstream mixing of the combustion products and the fresh fuel-air mixtures, thus to improve the flame stability and to control the combustion process. In the present paper, flames stabilized by a conical-shape bluff-body flame holder with a central air/fuel jet were studied. Effects of both a central air jet and a central fuel jet on the structures and lean blowout limits of the premixed annular flames, and on the temperature on the upper surface of the bluff-body were investigated and presented. It was revealed that a central jet led to a considerable reduction of the temperature on the upper surface of the bluff-body. It was proposed to be caused by the alternation of flow structures (in the case with a central air jet) altogether with the flame lifting from the burner (in the case with a central fuel jet). Thus, it might be used to solve the problem of the bluff-body with high heat loads in practical applications. The flame stability characteristics, for example the unstable flame dynamics and the lean blowout limits, varied with the injection of an air or fuel jet through the central pipe. Different blowout behaviors, being with or without the occurrence of flame split and flashing, caused by a central air jet were presented in the paper. In addition, when a small amount of central fuel jet (i.e., Uf/Ua = 0.045) was injected into the flow fields, an unsteady circular motion of the flame tip along the outer edge of the bluff-body was observed as well. Whereas, with an increase in the amount of the central fuel jet, the flame detached from the outer edge of the bluff-body and then became much more unstable. With a central air or fuel jet injecting into the flow field, premixed flames stabilized by the bluff-body became more unstable and easier to blowout. Date A point or period of time associated with an event in the lifecycle of the resource 2017 Subject The topic of the resource Bluff body, premixed flame, flame structures, flame instabilities, lean blowout Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/en10122011 Source A related resource from which the described resource is derived Energies Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Technology Language A language of the resource EN https://www.socictopen.socict.org/files/original/c60743122064f09152b5e14e877e8181.pdf 933a8a32089dfcc79c32981aaeba7d0c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Optimization of the CDC Protocol of Molecular Diagnosis of COVID-19 for Timely Diagnosis. Creator An entity primarily responsible for making the resource Yihui Huang, Po-Liang Lu, Chu-Feng Wang, Shang-Yi Lin, Shu-kai Lin, Chao-Ju Chen, Li-Ling Hsieh Description An account of the resource Coronavirus disease 2019 (COVID-19), the current uncontrolled outbreak of infectious disease, has caused significant challenges throughout the world. A reliable rapid diagnostic test for COVID-19 is demanded worldwide. The real-time reverse transcriptase polymerase chain was one of the most quickly established methods in the novel viral pandemic and was considered as the gold standard for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this report, we illustrate our experience of applying a protocol from the Taiwan CDC and achieving assay optimization in the immediate circumstances to meet the urgent medical and public health needs. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource molecular diagnostics, Coronavirus disease 2019 (COVID-19), real-time reverse transcriptase polymerase chain (RT-PCR), severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/diagnostics10050333 Source A related resource from which the described resource is derived Diagnostics Publisher An entity responsible for making the resource available MDPI AG https://www.socictopen.socict.org/files/original/7f9e7df894ac948e4bb218c1af8ab1fe.pdf d76655cdf96e936327c9b8487f1681b8 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Oil Flow Analysis in the Maritime Silk Road Region Using AIS Data Creator An entity primarily responsible for making the resource Yijia Xiao, Yanming Chen, Xiaoqiang Liu, Zhao Jinyan, Liang Cheng, Manchun Li Description An account of the resource Monitoring maritime oil flow is important for the security and stability of energy transportation, especially since the “21st Century Maritime Silk Road” (MSR) concept was proposed. The U.S. Energy Information Administration (EIA) provides public annual oil flow data of maritime oil chokepoints, which do not reflect subtle changes. Therefore, we used the automatic identification system (AIS) data from 2014 to 2016 and applied the proposed technical framework to four chokepoints (the straits of Malacca, Hormuz, Bab el-Mandeb, and the Cape of Good Hope) within the MSR region. The deviations and the statistical values of the annual oil flow from the results estimated by the AIS data and the EIA data, as well as the general direction of the oil flow, demonstrate the reliability of the proposed framework. Further, the monthly and seasonal cycles of the oil flows through the four chokepoints differ significantly in terms of the value and trend but generally show an upward trend. Besides, the first trough of the oil flow through the straits of Hormuz and Malacca corresponds with the military activities of the U.S. in 2014, while the second is owing to the outbreak of the Middle East Respiratory Syndrome in 2015. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource automatic identification system data, 21st Century Maritime Silk Road region, oil flow analysis, maritime oil chokepoint, Middle East respiratory syndrome Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/ijgi9040265 Source A related resource from which the described resource is derived ISPRS International Journal of Geo-Information Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Geography (General) Language A language of the resource EN https://www.socictopen.socict.org/files/original/f50742d758f032fab889a4b3faf37876.pdf 3c3b8395debe796344dcdc62f4daf04b Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Environmental Inequality Deepened During the COVID-19 in the Developing World. Creator An entity primarily responsible for making the resource Yilin Chen, Niru Senthilkumar, Huizhong Shen, Guofeng Shen Date A point or period of time associated with an event in the lifecycle of the resource 2021 Identifier An unambiguous reference to the resource within a given context 10.1021/acs.est.0c06193 Source A related resource from which the described resource is derived Environmental science & technology https://www.socictopen.socict.org/files/original/c1d6585ff1b44a0930333dba3e9f6453.pdf e89455d83888e6f9e5ea9f9d00af8acc Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Design, Synthesis and Investigation of the Potential Anti-Inflammatory Activity of 7-<i>O</i>-Amide Hesperetin Derivatives Creator An entity primarily responsible for making the resource Yilong Zhang, Yan Zheng, Wen Shi, Yahui Guo, Tao Xu, Zeng Li, Cheng Huang, Jun Li Description An account of the resource To develop new anti-inflammatory agents, a series of 7-O-amide hesperetin derivatives was designed, synthesized and evaluated for anti-inflammatory activity using RAW264.7 cells. All compounds showed inhibitory effect on LPS-induced NO production. Among them, 7-O-(2-(Propylamino)-2-oxoethyl)hesperetin (4d) and 7-O-(2-(Cyclopentylamino)-2-oxoethyl)hesperetin (4k) with hydrophobic side chains exhibited the most potent NO inhibitory activity (IC50 = 19.32 and 16.63 &#956;M, respectively), showing stronger inhibitory effect on the production of pro- inflammatory cytokines tumor necrosis factor (TNF-&#945;), interleukin-6 (IL-6) and interleukin-1&#946; (IL-1&#946;) than indomethacin and celecoxib at 10 &#956;M. The structure-activity relationships (SARs) suggested that the 7-O-amide unit was buried in a medium-sized hydrophobic cavity of the bound receptor. Furthermore, compound 4d could also significantly suppress the expression of inducible nitric oxide synthase enzymes (iNOS) and cyclooxygenase-2 (COX-2), through the nuclear factor-kappa B (NF-&#954;B) signaling pathway. Date A point or period of time associated with an event in the lifecycle of the resource 2019 Subject The topic of the resource hesperetin derivatives, Synthesis, Inflammatory, NF-κB, structure-activity relationships Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/molecules24203663 Source A related resource from which the described resource is derived Molecules Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Organic chemistry Language A language of the resource EN https://www.socictopen.socict.org/files/original/0f2e8ef93826459ac3744fe9403fad4e.pdf d85ad54bd13f9472675f063784509767 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Random Network Transmission and Countermeasures in Containing Global Spread of COVID-19-Alike Pandemic: A Hybrid Modelling Approach Creator An entity primarily responsible for making the resource Yimin Zhou, Jun Li, Lingjian Ye, Zuguo Chen, Qingsong Luo, Xiangdong Wu, Haiyang Ni Description An account of the resource Since the outbreak of the novel coronavirus disease (COVID-19) at the beginning of December 2019, there have been more than 28.69 million cumulative confirmed cases worldwide as of 12th September 2020, affecting over 200 countries and regions with more than 920,463 deaths. The COVID-19 pandemic has been sweeping worldwide with unexpected rapidity. In this paper, a hybrid modelling strategy based on tessellation structure- (TS-) configured SEIR model is adopted to estimate the scale of the pandemic spread. Building on the data pertaining to the global pandemic transmission over the last six months around the world, key impact factors in the transmission and control procedure have been analysed, including isolation rate, number of the infected cases before taking prevention measures, degree of contact scope, and medical level, so as to capture the fundamental factor influencing the pandemic. The quantitative evaluation allowed us to illustrate the magnitude of risks of pandemic and to recommend appropriate national health policy of prevention measures for effectively controlling both intra- and interregional pandemic spread. Our modelling results clearly indicate that the early-stage preventive measures are the most effective action to be taken to contain the pandemic spread of the highly contagious nature of the COVID-19. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.1155/2020/6703703 Source A related resource from which the described resource is derived Complexity Publisher An entity responsible for making the resource available Hindawi-Wiley Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Electronic computers. Computer science https://www.socictopen.socict.org/files/original/5605366a9dceb4e2355bd4467fb62308.pdf 1b40f1d434813e401feebb1be70acbdc Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Mental Health in Frontline Medical Workers during the 2019 Novel Coronavirus Disease Epidemic in China: A Comparison with the General Population Creator An entity primarily responsible for making the resource Yiming Liang, Kankan Wu, Yongjie Zhou, Xin Huang, Yueyue Zhou, Zhengkui Liu Description An account of the resource Background: Since December 2019, China has been affected by a severe outbreak of coronavirus disease 2019 (COVID-19). Frontline medical workers experienced difficulty due to the high risk of being infected and long and distressing work shifts. The current study aims to evaluate psychological symptoms in frontline medical workers during the COVID-19 epidemic in China and to perform a comparison with the general population. Methods: An online survey was conducted from 14 February 2020 to 29 March 2020. A total of 899 frontline medical workers and 1104 respondents in the general population participated. Depression, anxiety, insomnia, and resilience were assessed via the Patient Health Questionnaire (PHQ-9), Generalized Anxiety Disorder Scale (GAD-7), Insomnia Severity Index (ISI), and abbreviated Connor–Davidson Resilience Scale (CD-RISC-10), respectively. Results: Overall, 30.43%, 20.29%, and 14.49% of frontline medical workers in Hubei Province and 23.13%, 13.14%, and 10.64% of frontline medical workers in other regions reported symptoms of depression, anxiety, and insomnia, respectively. In addition, 23.33%, 16.67%, and 6.67% of the general population in Hubei Province and 18.25%, 9.22%, and 7.17% of the general population in other regions reported symptoms of depression, anxiety, and insomnia, respectively. The resilience of frontline medical staff outside Hubei Province was higher than that of the general population outside Hubei Province. Conclusion: A large proportion of frontline medical workers and the general public experienced psychological symptoms during the COVID-19 outbreak. Psychological services for frontline medical workers and the general public are needed. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource coronavirus, mental health, covid-19, General public, frontline medical workers Identifier An unambiguous reference to the resource within a given context 10.3390/ijerph17186550 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine