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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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        <name>Dublin Core</name>
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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Viral and atypical bacterial etiologies of severe acute respiratory infection (SARI) in Egyptian patients: epidemiological patterns and results from the sentinel surveillance study 2010–2014</text>
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            <name>Creator</name>
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                <text>Ashraf M Hatem, Usama E Abuelhassan, Sherif A.A. Mohamed, Magda S Rizk, Amany El-kholy, Mohamed Al-Harras</text>
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          <element elementId="41">
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            <description>An account of the resource</description>
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                <text>Background Respiratory viral and atypical bacterial infections data in Egyptian patients are sparse. This study described the epidemiological pattern of viral and atypical bacteria as causes for severe acute respiratory infections (SARI) in hospitalized patients in Egypt. Patients and methods SARI surveillance was carried out at a Teaching University Hospital during the period 2010–2014. All hospitalized adults and pediatric patients meeting the WHO case definition criteria for SARI were enrolled. Nasopharyngeal/oropharyngeal swabs were collected and samples were tested using reverse transcription-PCR for influenza A, B, respiratory syncytial virus, human metapneumovirus, parainfluenza viruses 1, 2, 3, 4, adenovirus, human bocavirus, coronavirus, enterovirus, rhinovirus, and atypical bacteria (Mycoplasma spp., Chlamydia spp., and Legionella spp.). Results Overall, 1075/3207 (33.5%) cases had a viral etiology, and included 912 (84.4%) women and 163 (15.6%) men, with a mean age of 5.74±13.87 years. The highest rates were reported for respiratory syncytial virus (485 cases, 45.2%), parainfluenza virus (125, 11.6%), and adenovirus (105, 9.8%). Single viral etiology was reported in 901 (83.3%), while 174 (16.7%) cases had multiple etiologies. Children had a higher rate (981, 91.2%) compared with 94 (8.8%) cases in adults. Only three and one cases were positive for Mycoplasma spp. and Chlamydia spp. infections, respectively. Neither coronavirus nor Legionella spp. were detected. Conclusion Viral infections were encountered in one-third of hospitalized Egyptian adult and pediatric patients with SARI. Atypical bacteria had a minor role in SARI in our locality. Ongoing surveillance programs will better describe the epidemiology of SARI and will provide specific data to enable decision makers to take appropriate prevention measures.</text>
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            <name>Date</name>
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              <elementText elementTextId="18029">
                <text>2019</text>
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            <name>Subject</name>
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                <text>bacterial, Egypt, Epidemiology, Severe Acute Respiratory Infection, Surveillance, Viral</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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                <text>DOI: 10.4103/ejcdt.ejcdt_96_18</text>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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                <text>Egyptian Journal of Chest Disease and Tuberculosis</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="18033">
                <text>Wolters Kluwer Medknow Publications</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Diseases of the respiratory system</text>
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                <text>EN</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
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                <text>The journey of remdesivir: from Ebola to COVID-19</text>
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            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="26404">
                <text>Ashutosh M Shukla, Joe Pardo, Gajapathiraju Chamarthi, Asmita Gupte</text>
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            <description>An account of the resource</description>
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                <text>Countries around the world are currently fighting the coronavirus disease 2019 (COVID-19) pandemic, which is caused by severe acute respiratory syndrome coronavirus 2 (SARSCoV- 2). SARS-CoV-2 is a betacoronavirus, belonging to the same genus as severe acute respiratory syndrome (SARS)-CoV and Middle East respiratory syndrome (MERS)-CoV. Currently, there are no proven antiviral therapies for COVID-19. Numerous clinical trials have been initiated to identify an effective treatment. One leading candidate is remdesivir (GS-5734), a broad-spectrum antiviral that was initially developed for the treatment of Ebola virus (EBOV). Although remdesivir performed well in preclinical studies, it did not meet efficacy endpoints in a randomized trial conducted during an Ebola outbreak. Remdesivir holds promise for treating COVID-19 based on in vitro activity against SARS-CoV-2, uncontrolled clinical reports, and limited data from randomized trials. Overall, current data are insufficient to judge the efficacy of remdesivir for COVID-19, and the results of additional randomized studies are eagerly anticipated. In this narrative review, we provide an overview of Ebola and coronavirus outbreaks. We then summarize preclinical and clinical studies of remdesivir for Ebola and COVID-19.</text>
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                <text>2020</text>
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                <text>Pandemic, remdesivir, SARS-CoV-2, COVID-19</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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                <text>DOI: 10.7573/dic.2020-4-14</text>
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                <text>Drugs in Context</text>
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            <name>Publisher</name>
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                <text>BioExcel Publishing Ltd</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Therapeutics. Pharmacology</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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          <element elementId="50">
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                <text>Interventional Stroke Care in the Era of COVID-19</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="23067">
                <text>Ashutosh P Jadhav, Hisham Salahuddin, Alicia C. Castonguay, Richard Burgess, Syed F. Zaidi, Mouhammad A. Jumaa</text>
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          <element elementId="41">
            <name>Description</name>
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              <elementText elementTextId="23068">
                <text>The current coronavirus disease (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 has led to immense strain on healthcare systems and workers. Patients with severe symptoms of COVID-19 may also present with acute neurological emergencies such as ischemic stroke. Ischemic stroke in these patients may result from COVID-19 related complications or decompensation of previously asymptomatic cerebrovascular disorders, or concurrent ischemic stroke from common stroke risk factors in a patient with COVID-19. Acute ischemic stroke patients with large vessel occlusions require emergent triage, intensive care, and mechanical thrombectomy. Management of patients with large vessel occlusions (LVO) requires special considerations in the current pandemic. Physicians must now account for prognosis of severe COVID-19, resource utilization, and risk of infection to healthcare workers when determining eligibility for mechanical thrombectomy (MT). Here, we describe important prognostic factors including age, laboratory, and imaging findings to consider for MT selection and provide suggestions for taking care of patients with LVO and possible or confirmed COVID-19. It is recommended to perform MT in patients within the established guidelines, and consider a conservative approach in cases where there is clinical equipoise to minimize futile reperfusion. Lastly, we describe an illustrative case of a patient with ischemic stroke and COVID-19.</text>
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                <text>2020</text>
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                <text>Stroke, thrombectomy, coronavirus, ischemic, Pandemic, COVID-19</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="23071">
                <text>DOI: 10.3389/fneur.2020.00468</text>
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              <elementText elementTextId="23072">
                <text>Frontiers in Neurology</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="23073">
                <text>Frontiers Media S.A.</text>
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                <text>Neurology. Diseases of the nervous system</text>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Comparing South Korea and Italy’s healthcare systems and initiatives to combat COVID-19</text>
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                <text>Ashwin Palaniappan, Udit Dave, Brandon Gosine</text>
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                <text>Italy and South Korea have two distinctly different healthcare systems, causing them to respond to public health crises such as the COVID-19 pandemic in markedly different ways. Differences exist in medical education for both countries, allowing South Korean medical graduates to have a more holistic education in comparison to their Italian counterparts, who specialize in medical education earlier on. Additionally, there are fewer South Korean physicians per 1000 people in South Korea compared to Italian physicians per 1000 people in Italy. However, both countries have a national healthcare system with universal healthcare coverage. Despite this underlying similarity, the two countries addressed COVID-19 in nearly opposite manners. South Korea employed technology and the holistic education of its physician community, despite having a smaller proportion of physicians in society, to its advantage by implementing efficacious drive-through centers that test suspected individuals rapidly and with little to no contact with healthcare staff, decreasing the possibility of transmission of COVID-19. Conversely, Italy is presently considered the epicenter of the outbreak in Europe and has recorded the highest death toll of any country outside of mainland China. This is partially due to the reactionary nature of Italy’s public health measures compared to South Korea’s proactive response. The different healthcare responses of South Korea and Italy can inform decisions made by public health bodies in other countries, especially in countries across the Americas, which can selectively adopt policies that have worked in curtailing the spread of COVID-19 and learn from mistakes made by both countries.</text>
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                <text>2020</text>
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                <text>Pneumonia, Viral, health systems, Virus Diseases, Pandemics, Coronavirus infection, SARS virus</text>
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                <text>DOI: 10.26633/RPSP.2020.53</text>
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                <text>Revista Panamericana de Salud Pública</text>
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                <text>Pan American Health Organization</text>
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                <text>Arctic medicine. Tropical medicine, Public aspects of medicine, Medicine</text>
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                <text>All the three Indian gastroenterology societies (Society of Gastrointestinal Endoscopy of India, Indian Society of Gastroenterology, and Indian National Association for the Study of the Liver) jointly recommend to consider only emergency and urgent endoscopy procedures for the next 1 month or till the current threat due to coronavirus disease 2019 (COVID-19) is over. Two laws that are penal in nature are now applicable in the current pandemic, namely the Epidemics Diseases Act 1897 and the Indian Penal Code 1860. No act of an endoscopist should be seen to be in contravention of any of the aforementioned laws, and the sections thereunder as provisions of the Indian Penal Code can be attracted in the current scenario for spreading an infectious disease either knowingly (Section 270) or unknowingly or negligently (Section 269). Section 4 of the Epidemics Disease Act 1897 gives legal protection to every person who has acted under this Act or the directions issued under this Act subject to only one condition, that is, the act must have been done in good faith. Though the hospitals are obliged to ensure personal safety of its staff legally, morally and ethically, because of the huge gap in demand and supply of personal protective equipment (PPE), it is advisable to arrange PPE on one’s own to first protect oneself and then, by extension, to prevent the spread to others. The dictum is “take care of yourself.” Self-preservation is a supreme law. In the current COVID-19 pandemic conditions, certain additional information, to be agreed upon by the patient, needs to be incorporated in the consent. It should be incorporated in the consent that: • While all the necessary precautions are being taken, there is a finite though small risk that the patient may contract the infection from the hospital. • He/she indemnifies the hospital and the endoscopist against any such liability arising out of any action taken while doing the procedure. • Furthermore, to protect the patient him/herself, he/she agrees to get the preprocedural test for COVID-19 as well as bear the additional cost of the PPE used by the endoscopist and support staff. Several of those who have undergone an endoscopy would require a follow-up consultation. As it is difficult to have physical interaction, teleconsultation may be done as per the telemedicine practice guidelines issued by the Medical Council of India (MCI).</text>
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                <text>Diseases of the digestive system. Gastroenterology</text>
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                <text>Ashwini M. Patil, Joachim R. Göthert, Vishal Khairnar</text>
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                <text>Cellular Physiology and Biochemistry</text>
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                <text>Cell Physiol Biochem Press GmbH &amp; Co KG</text>
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                <text>COVID-19 as the equalizer": Evolving discourses of COVID-19 and implications for medical education."</text>
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                <text>Asia van Buuren, Vincent Tang, Maria Athina Tina Martimianakis</text>
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                <text>Canadian medical education journal</text>
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                <text>Los retos de la seguridad energética y el cambio climático: hacia una economía europea sostenible</text>
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                <text>Asier García Lupiola</text>
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                <text>El desarrollo sostenible se configura como objetivo general de la integración europea, de manera que el crecimiento económico sea compatible con la protección del medio ambiente. Desde hace ya varios años el mayor reto en esta materia es la lucha contra el cambio climático, al que se ha sumado, por su creciente gravedad, la seguridad de abastecimiento energético. Se trata de dos desafíos que actualmente se encuentran vinculados por las herramientas que se proponen desde la UE para afrontarlos, principalmente, el impulso de las energías renovables y la eficiencia energética.Recibido: 17 diciembre 2018Aceptado: 14 enero 2019Publicación en línea: 30 abril 2019</text>
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                <text>Cuadernos Europeos de Deusto</text>
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                <text>Universidad de Deusto</text>
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                <text>Political science, International relations, Law of Europe</text>
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                <text>Impactos, vulnerabilidad y adaptación al Cambio Climático en los bosques ibéricos.</text>
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                <text>Se han registrado numerosos impactos relacionados con el cambio climático en los bosques ibéricos que pueden cambiar la composición, estructura y funcionamiento de los mismos.Es importante considerar que los efectos del cambio climático interactúan comúnmente con otros motores de cambio, dificultando de esta manera la cuantificación de la contribución delcambio climático en los impactos observados. Entre los impactos registrados encontramos alteraciones fisiológicas, fenológicas, demográficas y de distribución, las cuales a su vez puedenprovocar cambios en la composición, estructura y funcionamiento de los ecosistemas forestales ibéricos. A medida que el cambio climático avance, y las condiciones climáticas se alejen cadavez más de las actuales, se espera un aumento de los impactos observados. En este contexto, se hace necesario evaluar correctamente la vulnerabilidad de poblaciones, especies y ecosistemas frente al cambio climático futuro para poder diseñar y aplicar medidas de adaptación eficaces que minimicen los impactos y favorezcan el proceso de ajuste a las nuevas condiciones. La aplicación de las medidas de adaptación debe enmarcarse en una gestión adaptativa y anticipadora, que fomente la colaboración activa entre todos los actores involucrados en la gestión e investigación de los bosques ibéricos.</text>
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                <text>Adaptación, Cambio climático, Vulnerabilidad, bosques</text>
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                <text>Munibe Ciencias Naturales</text>
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                <text>Sociedad de Ciencias Aranzadi</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>On a Discrete SEIR Epidemic Model with Exposed Infectivity, Feedback Vaccination and Partial Delayed Re-Susceptibility</text>
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                <text>Asier Ibeas, Manuel  De la Sen, Santiago Alonso-Quesada</text>
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                <text>A new discrete Susceptible-Exposed-Infectious-Recovered (SEIR) epidemic model is proposed, and its properties of non-negativity and (both local and global) asymptotic stability of the solution sequence vector on the first orthant of the state-space are discussed. The calculation of the disease-free and the endemic equilibrium points is also performed. The model has the following main characteristics: (a) the exposed subpopulation is infective, as it is the infectious one, but their respective transmission rates may be distinct; (b) a feedback vaccination control law on the Susceptible is incorporated; and (c) the model is subject to delayed partial re-susceptibility in the sense that a partial immunity loss in the recovered individuals happens after a certain delay. In this way, a portion of formerly recovered individuals along a range of previous samples is incorporated again to the susceptible subpopulation. The rate of loss of partial immunity of the considered range of previous samples may be, in general, distinct for the various samples. It is found that the endemic equilibrium point is not reachable in the transmission rate range of values, which makes the disease-free one to be globally asymptotically stable. The critical transmission rate which confers to only one of the equilibrium points the property of being asymptotically stable (respectively below or beyond its value) is linked to the unity basic reproduction number and makes both equilibrium points to be coincident. In parallel, the endemic equilibrium point is reachable and globally asymptotically stable in the range for which the disease-free equilibrium point is unstable. It is also discussed the relevance of both the vaccination effort and the re-susceptibility level in the modification of the disease-free equilibrium point compared to its reached component values in their absence. The influences of the limit control gain and equilibrium re-susceptibility level in the reached endemic state are also explicitly made viewable for their interpretation from the endemic equilibrium components. Some simulation examples are tested and discussed by using disease parameterizations of COVID-19.</text>
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                <text>2021</text>
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                <text>covid-19 pandemic, discrete epidemic model, feedback vaccination control, transmission rate of the exposed, transmission rate of the infectious, delayed re-susceptibility (or immunity loss)</text>
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                <text>10.3390/math9050520</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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                <text>Epidemiology and Health</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>Korean Society of Epidemiology</text>
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            <name>Coverage</name>
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                <text>Mathematics</text>
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