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                <text>Are promising mechanisms of hydroxychloroquine abolish COVID-19 activity? A review study</text>
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                <text>Yaareb J Mousa, Mahmood B. Mahmood, Fanar A. Isihaq, Ammar A. Mohammed</text>
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                <text>To explore the benefits of Hydroxychloroquine (HCQ), (which is an antimalarial agent that has shown effective pharmacological properties in different malarial conditions and immunological disorders, particularity in chloroquine-sensitive malaria), in the treatment and prevention of Corona Virus Disease-2019 (COVID-19) pandemic because HCQ was recently advocated to minimize the pathogenicity of COVID-19. The aim of this review is to shed the light on a possible mechanism by which HCQ can defeat the COVID-19, a disease characterized by the WHO as a pandemic. Literatures from Web of Science, Scopus, PubMed, Science Direct and Google Scholar were cast-off to search the literature data. The keywords used are antimalarial agent, COVID-19, Hydroxychloroquine, SARS-CoV-2 and Zinc sulfate.The review summarizes the benefits of using HCQ against COVID-19 through exploiting the ability of this antimalarial agent in ameliorating the body immunity, inhibiting and/or delaying the viral glycosylation by increasing the pH inside the host cell and also via suppressing the viral transcription and replication through the formation of a complex structure after binding with zinc. We concluded thatthese interfering properties of HCQ support human immunity to fight against the progression of COVID-19. We hypothesize that the therapeutic efficiency of HCQ against the COVID-19 can be enhanced by the concurrent administration of zinc sulfate.</text>
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                <text>10.33899/ijvs.2020.127049.1449</text>
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                <text>Iraqi Journal of Veterinary Sciences</text>
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                <text>University of Mosul, College of Veterinary Medicine</text>
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                <text>Veterinary medicine</text>
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                <text>Are Proton Pump Inhibitors Contributing to SARS-COV-2 Infection?</text>
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                <text>Branden Tarlow, John Gubatan, Muhammad Ali Khan, George Cholankeril</text>
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                <text>The American journal of gastroenterology</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Are SAARC countries prepared to combat COVID-19 to save young, working-age population?</text>
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                <text>Farhana Sultana, Hasan Mahmud Reza</text>
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                <text>The COVID-19 outbreak has expanded across the globe. Most of the countries are launching different measures to stop the transmission of this virus. However, the death toll is steadily rising. Strikingly the rate of coronavirus infection among the young-age population is the highest in SAARC countries as more than 80% population of the SAARC countries are young who constitute the working-age group. The disease transmission also occurs at a slower rate presumably due to diverse lifestyles of different ethnicities, immunity and genetic traits; but not because of the hot and humid weather despite previous assumptions. Since SAARC countries comprise 23.75% of the world population and the largest portion of these people is the young working-class, some immediate measures need to be implemented to save these valuable lives from COVID-19. Till now, there is no specific treatment or vaccine available; hence timely-taken preventive measures are the only hope that can save the people of this region. Here we have demonstrated an altered disease transmission pattern in people of SAARC countries, measures initiated by the governments, causes of failure and further actions to be taken to control disease transmission.</text>
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                <text>2020</text>
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                <text>covid-19, climate, SAARC, young population</text>
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            <name>Identifier</name>
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                <text>10.3934/publichealth.2020036</text>
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            <description>A related resource from which the described resource is derived</description>
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                <text>Biotemas</text>
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              <elementText elementTextId="85551">
                <text>Universidade Federal de Santa Catarina</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="85552">
                <text>Public aspects of medicine</text>
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  <item itemId="1803" public="1" featured="0">
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              <name>Title</name>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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              </elementTextContainer>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="17280">
                <text>Are SARS Superspreaders Cloud Adults?</text>
              </elementText>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="17281">
                <text>Stefano Bassetti, Werner E. Bischoff, Robert J. Sherertz</text>
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            <name>Date</name>
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                <text>2005</text>
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                <text>SARS virus, Staphylococcus aureus, Transmission, Letter</text>
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                <text>DOI: 10.3201/eid1104.040639</text>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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                <text>Emerging Infectious Diseases</text>
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                <text>Centers for Disease Control and Prevention</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Infectious and parasitic diseases, Medicine</text>
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                <text>EN</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="3485">
                <text>Are saving appearance responses typical communication patterns in Alzheimer's disease?</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="3486">
                <text>Masateru Matsushita, Yusuke Yatabe, Asuka Koyama, Akiko Katsuya, Daisuke Ijichi, Yusuke Miyagawa, Hiroto Ikezaki, Noboru FURUKAWA, Manabu Ikeda, Mamoru Hashimoto</text>
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                <text>INTRODUCTION:To keep up appearances, people with dementia sometimes pretend to know the correct answer, as seen during administration of neuropsychological tests such as the Mini-Mental State Examination (MMSE). These saving appearance responses (SARs) of people with dementia often lead to caregivers and/or medical staff underestimating the severity of dementia and impede proper early initiation of treatment. However, most descriptions of SARs are based on empirical knowledge of clinicians. In this study, we investigated whether SARs are typical communication patterns in people with Alzheimer's disease (AD), compared with mild cognitive impairment (MCI) or dementia with Lewy bodies (DLB). METHODS:The participants were 107 outpatients with AD, 16 with mixed AD with cerebrovascular dementia, 55 with MCI, and 30 with DLB. We assessed the occurrence of SARs during the MMSE. The relationships between the SARs and AD were examined by the χ2 test and logistic regression analysis. RESULTS:People with AD who showed SARs were 57.9%, whereas those with MCI were 18.2% and DLB were 20.0% (P with Bonferroni correction &lt; 0.05). Although there were significant differences in some variables in each group of diagnosis, logistic regression analysis showed that people with AD were more likely to show SARs than those with MCI (Odds ratio = 3.48, 95% Confidential Interval = 1.18-10.28) and DLB (Odds ratio = 4.24, 95% Confidential Interval = 1.50-12.01), even after controlling for sex, estimated disease duration, MMSE, and frontal assessment battery scores. CONCLUSION:The occurrence of SARs could be found most frequently in people with AD. Clinicians should develop a respectful attitude toward dementia patients with SARs because SARs imply conflicted feelings about questions that patients cannot answer correctly.</text>
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                <text>2018</text>
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                <text>DOI: 10.1371/journal.pone.0197468</text>
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              <elementText elementTextId="3490">
                <text>PLoS ONE</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Agriculture (General), Agriculture</text>
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            <name>Relation</name>
            <description>A related resource</description>
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                <text>&lt;a href="http://revistas.udenar.edu.co/index.php/rfacia/article/view/3690/4409" target="_blank" rel="noreferrer noopener"&gt;http://revistas.udenar.edu.co/index.php/rfacia/article/view/3690/4409&lt;/a&gt;</text>
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