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                  <text>Dominio científico: Coronavirus</text>
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                <text>From Multiplex Serology to Serolomics—A Novel Approach to the Antibody Response Against the SARS-CoV-2 Proteome</text>
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                <text>Barbara Müller, Julia Butt, Rajagopal Murugan, Theresa Hippchen, Sylvia Olberg, Monique van Straaten, Hedda Wardemann, Erec Stebbins, Hans-Georg Kräusslich, Ralf Bartenschlager, Hermann Brenner, Vibor Laketa, Ben Schöttker, Uta Merle, Tim Waterboer</text>
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                <text>The emerging SARS-CoV-2 pandemic entails an urgent need for specific and sensitive high-throughput serological assays to assess SARS-CoV-2 epidemiology. We, therefore, aimed at developing a fluorescent-bead based SARS-CoV-2 multiplex serology assay for detection of antibody responses to the SARS-CoV-2 proteome. Proteins of the SARS-CoV-2 proteome and protein N of SARS-CoV-1 and common cold Coronaviruses (ccCoVs) were recombinantly expressed in E. coli or HEK293 cells. Assay performance was assessed in a COVID-19 case cohort (n = 48 hospitalized patients from Heidelberg) as well as n = 85 age- and sex-matched pre-pandemic controls from the ESTHER study. Assay validation included comparison with home-made immunofluorescence and commercial enzyme-linked immunosorbent (ELISA) assays. A sensitivity of 100% (95% CI: 86–100%) was achieved in COVID-19 patients 14 days post symptom onset with dual sero-positivity to SARS-CoV-2 N and the receptor-binding domain of the spike protein. The specificity obtained with this algorithm was 100% (95% CI: 96–100%). Antibody responses to ccCoVs N were abundantly high and did not correlate with those to SARS-CoV-2 N. Inclusion of additional SARS-CoV-2 proteins as well as separate assessment of immunoglobulin (Ig) classes M, A, and G allowed for explorative analyses regarding disease progression and course of antibody response. This newly developed SARS-CoV-2 multiplex serology assay achieved high sensitivity and specificity to determine SARS-CoV-2 sero-positivity. Its high throughput ability allows epidemiologic SARS-CoV-2 research in large population-based studies. Inclusion of additional pathogens into the panel as well as separate assessment of Ig isotypes will furthermore allow addressing research questions beyond SARS-CoV-2 sero-prevalence.</text>
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                <text>2021</text>
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                <text>SARS-CoV-2, multiplex serology</text>
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                <text>10.3390/v13050749</text>
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                <text>Epidemiology and Health</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Microbiology</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>COVID-19: What Is Next for Portugal?</text>
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                <text>Bárbara Peleteiro, Ahmed Nabil Shaaban, Maria Rosario O. Martins, Bárbara Peleteiro, Ahmed Nabil Shaaban</text>
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                <text>Highly infectious with the possibility of causing severe respiratory complications, the novel COVID-19 began stretching health systems beyond their capacity all over the world and pushing them to breaking points. Giving the devastating effects caused by this infection, unprecedented measures have to be adopted in order to mitigate its impacts on the health system. This perspective aims to review the epidemic of COVID-19 in Portugal, possible areas of improvement, and potential interventions that can help to mitigate the effect of COVID-19 on the Portuguese health system.</text>
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                <text>2020</text>
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            <description>The topic of the resource</description>
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                <text>mental health, covid-19, economic crisis, health system, quality indicators–health care, health inequalites</text>
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            <name>Identifier</name>
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              <elementText elementTextId="84671">
                <text>10.3389/fpubh.2020.00392</text>
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                <text>Epidemiology and Health</text>
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            <name>Publisher</name>
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              <elementText elementTextId="84673">
                <text>Korean Society of Epidemiology</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Public aspects of medicine</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
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            <name>Title</name>
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                <text>The potential of herbal extracts to inhibit SARS-CoV-2: a pilot study</text>
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            <name>Creator</name>
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                <text>Barbara Schmidt, Michela Luisa De Pellegrin, Anette Rohrhofer, Philipp Schuster, Philipp Peterburs, André Gessner</text>
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                <text>Abstract Background Herbal medicinal products have a long-standing history of use in the therapy of common respiratory infections. We sought to assess the potential of five validated herbal extracts regarding their ability to restrict SARS-CoV-2 replication in vitro: Bronchipret thyme-ivy (BRO TI), Bronchipret thyme-primrose (BRO TP), Imupret (IMU), Sinupret extract (SINx) and Tonsipret (TOP). Methods Vero cells were incubated with different concentrations of herbal extracts and infected with SARS-CoV-2 for 48 hours. The inhibition of viral replication was assessed by determination of the viral RNA load in the cell culture supernatant using quantitative polymerase chain reaction (qPCR). Results SARS-CoV-2 RNA load was reduced by non-cytotoxic concentrations of BRO-TP (up to approximately 1,000-fold) and, to a lesser extent, IMU and TOP (approximately 10-fold). Conclusions Some herbal extracts showed a promising in vitro effectiveness against SARS-CoV-2, suggesting an antiviral potential of herbal medicinal products. The potential of herbal medicines to restrict SARS-CoV-2 and to treat COVID-19 should be investigated further in a clinical setting.</text>
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                <text>2021</text>
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                <text>viral replication, SARS-CoV-2, Bronchipret thyme-ivy (BRO TI), Bronchipret thyme-primrose (BRO TP), Imupret (IMU), Sinupret extract (SINx)</text>
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            <name>Identifier</name>
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              <elementText elementTextId="53130">
                <text>10.1186/s40816-021-00264-6</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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                <text>Epidemiology and Health</text>
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            <name>Publisher</name>
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              <elementText elementTextId="53132">
                <text>Korean Society of Epidemiology</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Medicine, Homeopathy</text>
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                  <text>Agricultura sostenible</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Agricultura sostenible</text>
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                <text>Investigating the domestication of convergent mobile media and mobile internet by children and teens: preliminary issues and empirical findings on opportunities and risks</text>
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            <name>Creator</name>
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              <elementText elementTextId="219293">
                <text>Barbara Scifo</text>
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            <description>An account of the resource</description>
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                <text>The paper, starting with some preliminary considerations about the new mobile media ecology, in which today's children live, and with some data about the diffusion of mobile internet and smartphones among children, aims to focus on three main points. I first ponder the new opportunities and new risks arising for children from the diffusion of such technologies, and the related usage practices, looking at some preliminary empirical findings, coming from qualitative researches I conducted with some of my colleagues from OssCom (Giovanna Mascheroni and Maria Francesca Murru), about the domestication of smartphones, mobile social networking and location-based practices in the Italian youth context. Then, I explore the new challenges in parental mediation, starting from qualitative evidence gathered from Italian parents. I finish illustrating the contribution of the new European project Net Children Go Mobile towards filling the current knowledge gap regarding European children’s mobile internet and convergent mobile media use, risks and online safety.  Investigación de la domesticación de la convergencia de los medios móviles e internet móvil por parte de niños y adolescentes: cuestiones previas y hallazgos empíricos sobre las oportunidades y riesgos  Resumen  A partir de algunas consideraciones preliminares sobre la nueva ecología de los medios móviles, en los que los niños de hoy viven, y con algunos datos sobre la difusión de Internet móvil y los teléfonos inteligentes, este documento tiene como objetivo centrarse en tres puntos principales. El primero, reflexionar sobre las nuevas oportunidades y nuevos riesgos para los niños con este tipo de tecnologías, y las prácticas de uso relacionados, mirando a algunos hallazgos empíricos preliminares, procedentes de investigaciones cualitativas que llevé a cabo con algunos de mis colegas de OssCom (Giovanna Mascheroni y Maria Francesca Murru), acerca de la domesticación de los teléfonos inteligentes, las redes sociales móviles y las prácticas basadas en la localización en el contexto de la juventud italiana. A continuación, se exploran los nuevos retos en la mediación de los padres, a partir de la evidencia cualitativa obtenida de padres italianos. Acabo de ilustrar la contribución del nuevo proyecto europeo Net niños Go Mobile, para llenar la brecha de conocimiento actual con respecto a los niños de Europa y el Internet móvil, el uso de medios móviles convergentes, los riesgos y la seguridad en línea.  Palabras clave: Medios de comunicación móviles; Internet móvil; niños; oportunidades; riesgos.</text>
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                <text>2013</text>
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            <name>Subject</name>
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                <text>Children, Opportunities, mobile Internet, mobile media, risks</text>
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                <text>10.25029/od.2013.9.4</text>
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                <text>Obra Digital</text>
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                <text>Universitat de Vic - Universitat Central de Catalunya</text>
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                <text>Communication. Mass media</text>
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                <text>&lt;a href="http://revistesdigitals.uvic.cat/index.php/obradigital/article/view/9" target="_blank" rel="noreferrer noopener"&gt;http://revistesdigitals.uvic.cat/index.php/obradigital/article/view/9&lt;/a&gt;</text>
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                <text>The Future of Fashion: How the Quest for Digitization and the Use of Artificial Intelligence and Extended Reality Will Reshape the Fashion Industry After COVID-19</text>
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                <text>The aim of this paper is to analyze how extended reality (formed by virtual and augmented reality), and artificial intelligence are influencing the fashion field. During and after the Covid19 pandemic, a radical shift happened: most activities, from shopping to showrooms and fashion weeks had to move online. While e-commerce was already a consolidated pillar of fashion shopping, it recently started to evolve to achieve through AR (augmented reality) and VR (virtual reality) what customers could before find in physical stores: interesting experiences and sensory stimuli. Online traffic peaked, creating even more room for technology based on artificial intelligence. With its disrupting powers, AI (artificial intelligence) has all the potentialities to take over each step of the fashion value chain. Furthermore, with the quarantine the production of fashion was slowed down by the absence of workers in production sites. Artificial intelligence and automation could be an answer. In this paper AR, VR and AI technologies are analyzed with practical examples on what has happened and is happening in the industry, from a perspective based on the challenges imposed by Covid-19. Results indicate that AR, VR and AI have the potential to become in the near future the norm in the fashion media and technology ecosystem, reinforcing the digitization process of the industry.</text>
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                <text>covid-19, Virtual Reality, artificial intelligence, augmented reality, Fashion</text>
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                <text>10.6092/issn.2611-0563/11803</text>
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                <text>ZoneModa Journal</text>
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            <name>Publisher</name>
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                <text>University of Bologna</text>
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                <text>Fine Arts, Visual arts</text>
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                  <text>Agricultura sostenible</text>
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                <text>Percepciones de cambio climático y respuestas adaptativas de pequeños agricultores en dos paisajes guatemaltecos</text>
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                <text>Bárbara Viguera, Francisco Alpízar, Celia A. Harvey, M. Ruth Martínez-Rodríguez, Milagro Saborío-Rodríguez, Lucía Contreras</text>
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                <text>Introducción. Se espera que, a consecuencia del cambio climático, cultivos como el café (Coffea arabica L.), maíz (Zea mays) y frijol (Phaseolus vulgaris L.) sean menos productivos en América Central. Esto perjudicará la economía regional y los medios de vida de los pequeños productores, quienes dependen de estos cultivos para su seguridad alimentaria y bienestar. Es necesario entender cómo el cambio climático está afectando a los pequeños productores agrícolas en Guatemala para promover medidas que permitan enfrentar estos cambios. Objetivo. El objetivo de este trabajo fue caracterizar dos sistemas agrícolas de pequeña escala guatemaltecos, documentar cómo los pequeños productores perciben los impactos del cambio climático e identificar los esfuerzos de adaptación realizados. Materiales y métodos. Se realizaron encuestas estructuradas en hogares productores de café o granos básicos en los paisajes de Acatenango y Chiquimula, vulnerables al cambio climático, entre junio y julio de 2014. La investigación recogió las percepciones de los productores sobre cambios en temperatura y lluvia, los impactos reportados como consecuencia de dichos cambios y las acciones implementadas en las fincas a modo de respuesta. Resultados. Los resultados indicaron que el 95 % de los encuestados percibió cambios en el clima en la última década y el 81 % consideró que estos cambios afectaron negativamente su producción. El 41 % de los productores implementaron prácticas para adaptarse a los cambios percibidos, en mayor medida aquellos que producen café. Las prácticas de adaptación implementadas en las fincas difirieron entre paisajes, cultivos y cambio percibido, siendo la más utilizada la siembra de árboles para amortiguar los efectos del incremento de temperatura. Conclusión. Para lograr una mayor respuesta adaptativa de los pequeños productores y para promover el uso de prácticas que incrementen su resiliencia, es necesario incrementar el apoyo técnico, financiero y político orientado a facilitar la adaptación de los pequeños productores ante el cambio climático.</text>
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                <text>2019</text>
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            <description>The topic of the resource</description>
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                <text>Adaptación, café, granos básicos, manejo de finca, percepción de cambio climático</text>
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                <text>Agronomía Mesoamericana</text>
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            <name>Publisher</name>
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                <text>Universidad de Costa Rica</text>
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                <text>Agriculture</text>
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                <text>&lt;a href="https://revistas.ucr.ac.cr/index.php/agromeso/article/view/33938" target="_blank" rel="noreferrer noopener"&gt;https://revistas.ucr.ac.cr/index.php/agromeso/article/view/33938&lt;/a&gt;</text>
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                <text>Percepciones de cambio climático y respuestas adaptativas de caficultores costarricenses de pequeña escala</text>
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              <elementText elementTextId="195781">
                <text>Bárbara Viguera, Francisco Alpízar, Milagro Saborío-Rodríguez, Celia A. Harvey, M. Ruth Martínez-Rodríguez</text>
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                <text>Introducción. El cambio climático afectará la distribución, productividad y rentabilidad del cultivo de café en América Central, perjudicando las economías nacionales y los medios de vida de los pequeños productores. Es necesario entender cómo el cambio climático está afectando a los pequeños caficultores en la región para promover medidas que permitan enfrentar estos cambios y adaptarse a ellos. Objetivo. El objetivo de este trabajo fue describir los sistemas cafetaleros costarricenses de pequeña escala en dos zonas productivas y explorar los esfuerzos de adaptación al cambio climático que realizan los productores. Materiales y métodos. Entre marzo y mayo de 2014, se realizaron encuestas estructuradas en hogares cafetaleros de dos paisajes vulnerables al cambio climático: Turrialba y Los Santos. El estudio se centró en las percepciones de los productores sobre los cambios en temperatura y lluvia, los impactos reportados como consecuencia de dichos cambios y las acciones de adaptación implementadas en las fincas. Resultados. Los resultados indicaron que el 98 % de los productores percibió cambios en el clima, gran parte de ellos los asociaron con impactos sobre su producción de café, y el 60 % de los encuestados realizó cambios en el manejo de sus cafetales para reducir los efectos del cambio climático. Las prácticas de adaptación más frecuentes fueron sembrar árboles e incrementar el uso de agroquímicos, en mayor medida en respuesta al incremento de temperatura. Conclusión. Este estudio destaca la necesidad de incrementar el apoyo técnico, financiero y político orientado a fomentar y diversificar la implementación de prácticas de adaptación entre pequeños caficultores e incrementar su resiliencia ante el cambio climático.</text>
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                <text>2019</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>adaptación al cambio climático, adaptación basada en ecosistemas, políticas ambientales, pérdidas de producción</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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                <text>10.15517/am.v30i2.32905</text>
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                <text>Agronomía Mesoamericana</text>
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                <text>Universidad de Costa Rica</text>
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                <text>&lt;a href="https://revistas.ucr.ac.cr/index.php/agromeso/article/view/32905" target="_blank" rel="noreferrer noopener"&gt;https://revistas.ucr.ac.cr/index.php/agromeso/article/view/32905&lt;/a&gt;</text>
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                  <text>Agricultura sostenible</text>
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                  <text>Dominio científico: Agricultura sostenible</text>
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      <name>Text</name>
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                <text>Patios Productivos como Estrategia para la Consolidación de la Educación Ambiental</text>
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                <text>Bárbara Ysabel Díaz Vásquez</text>
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            <description>An account of the resource</description>
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                <text>El estudio centró el objetivo general en proponer patios productivos como estrategia para la consolidación de la educación ambiental en los docentes de la Escuela Básica “Francisco Rivas”, ubicada en el municipio Barinas, estado Barinas. La investigación estuvo enmarcada en el enfoque cuantitativo, insertado en la modalidad de Proyecto Factible y apoyado en un estudio campo de carácter descriptivo. La población y muestra estuvo constituida por sesenta y cinco (65) educadores de la institución antes referida. De allí, se tomó en consideración la totalidad de la misma para la muestra. En cuanto, a la recolección de la información se utilizó una encuesta tipo cuestionario tipo Likert con cinco (05) alternativas de respuestas: Siempre, Casi Siempre, Algunas Veces, Casi Nunca y Nunca. Por consiguiente, el mismo fue validado por jueces o expertos aplicando el coeficiente de consistencia interna de Cronbach (alfa). El estudio concluye: Los profesionales de la docencia necesitan la utilización del desarrollo sustentable en la consolidación de la educación ambiental; así como los docentes carecen de la utilización del desarrollo endógeno en la promoción de los patios productivos como estrategia en la institución. También, tienen ausencia de emplear los valores ambientales para impulsar los patios productivos en la institución y comunidad. Los educadores con poca frecuencia mantienen un comportamiento con una actitud positiva hacia la consolidación de los patios productivos en la escuela.</text>
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                <text>2018</text>
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                <text>Educación Ambiental, medio ambiente, seguridad alimentaria</text>
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                <text>10.29394/Scientific.issn.2542-2987.2018.3.10.2.40-60</text>
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                <text>Revista Scientific</text>
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              <elementText elementTextId="169538">
                <text>Instituto Internacional de Investigación y Desarrollo Tecnológico Educativo</text>
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                <text>LOS HUMEDALES ANTE EL CAMBIO CLIMÁTICO</text>
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                <text>Bárbaro V. Moya, Ana E. Hernández, Héctor Elizalde Borrell</text>
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                <text>Las emisiones antropogénicas y naturales a la atmósfera, al aumento de concentración de gases de efecto invernadero, el calentamiento global, el cambio climático y el cambio global son hoy situaciones muy preocupantes para la comunidad científica internacional. Las vulnerabilidades, los impactos y las medidas de adaptación a escenarios futuros del clima, son una prioridad para la que ya vienen trabajando científicos y especialistas. Los humedales, ecosistemas con vulnerabilidad natural a los embates del clima, según el tercer informe del IPCC, han sido poco estudiados en su relación con el cambio del clima. Recientemente Ramsar ha solicitado al IPCC el desarrollo de un informe técnico sobre la relación de los humedales y el cambio climático, sin embargo, existe hoy una gama de conocimientos, que a pesar de las incertidumbres, permite tener un acercamiento a la acción del cambio climático sobre los humedales. En el presente estudio se muestra un análisis preliminar sobre vulnerabilidades, impactos y medidas de adaptación de los humedales al cambio climático.</text>
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                <text>2005</text>
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                <text>Universidad Nacional Autónoma de México</text>
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                <text>Geography (General)</text>
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                  <text>Agricultura sostenible</text>
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                <text>ANÁLISIS PRELIMINAR DE CAMBIO CLIMÁTICO EN LA CIÉNAGA DE ZAPATA</text>
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                <text>La Ciénaga de Zapata es el mayor humedal del Caribe insular. Es un humedal frágil y vulnerable al cambio climático. El presente trabajo hace un análisis preliminar de la relación de la Ciénaga de Zapata con el cambio climático. El análisis muestra apuntes sociales y económicos que caracterizan al humedal. Se plantean algunos de los valores ecológicos de la ciénaga como parte de esta caracterización y a continuación se muestran vulnerabilidades del ecosistema ante el cambio climático, los impactos de este cambio en el humedal y se da una serie de medidas de adaptación, que culminan con la propuesta de un proyecto integral con una serie de salidas que permitan atenuar las incertidumbres y favorecer la explotación y manejo del humedal. En la propuesta de proyecto se incluye también el humedal de Majaguillar ubicado en la costa Norte de la provincia de Matanzas.</text>
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                <text>Universidad Nacional Autónoma de México</text>
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                <text>Geography (General)</text>
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                <text>&lt;a href="http://www.redalyc.org/articulo.oa?id=17612755005" target="_blank" rel="noreferrer noopener"&gt;http://www.redalyc.org/articulo.oa?id=17612755005&lt;/a&gt;</text>
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