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Abnormal Iron Homeostasis and Neurodegeneration
Abnormal iron metabolism is observed in many neurodegenerative diseases, however only two have shown dysregulation of brain iron homeostasis as the primary cause of neurodegeneration. Herein, we review one of these - hereditary ferritinopathy (HF) or…
Position: 6823 (30 views)
Comparative pathogenesis of three human and zoonotic SARS-CoV strains in cynomolgus macaques.
The severe acute respiratory syndrome (SARS) epidemic was characterized by increased pathogenicity in the elderly due to an early exacerbated innate host response. SARS-CoV is a zoonotic pathogen that entered the human population through an…
Position: 1576 (54 views)
Nonhuman primate models for SARS.
Position: 16991 (18 views)
Livestock Susceptibility to Infection with Middle East Respiratory Syndrome Coronavirus
Middle East respiratory syndrome (MERS) cases continue to be reported, predominantly in Saudi Arabia and occasionally other countries. Although dromedaries are the main reservoir, other animal species might be susceptible to MERS coronavirus…
Position: 10225 (25 views)
Sargramostim to treat patients with acute hypoxic respiratory failure due to COVID-19 (SARPAC): A structured summary of a study protocol for a randomised controlled trial
Abstract Objectives The hypothesis of the proposed intervention is that Granulocyte-macrophage colony-stimulating factor (GM-CSF) has profound effects on antiviral immunity, and can provide the stimulus to restore immune homeostasis in the lung with…
Position: 11138 (24 views)
Predictability and epidemic pathways in global outbreaks of infectious diseases: the SARS case study
Abstract Background The global spread of the severe acute respiratory syndrome (SARS) epidemic has clearly shown the importance of considering the long-range transportation networks in the understanding of emerging diseases outbreaks. The…
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HIV and SARS-Coronavirus-2 Epidemics: Possible Interactions and Need for Studies, Especially in Africa
Position: 17836 (17 views)
La Huerta de Cabra, paisaje roto
La Huerta de Cabra es un referente ineludible de los paisajes y regadíos tradicionales del interior de la España meridional. Situadas en el contacto entre la campiña y la Subbética cordobesa, deben su existencia al importante caudal que brota de la…
Position: 8706 (27 views)
A New Vaccine to Battle Covid-19.
Position: 16083 (19 views)
COVID-19 Pandemisi Sırasında Türkiye’de Acil Servislerin Organizasyonu ve Değişen Hasta Profili
COVID-19 salgını sırasında acil servisler hastaların tanımlanması, izolasyonu, hastane içi enfeksiyonları önlenme ve halk sağlığı otoritelerini bilgilendirmede önemli görevler üstlenir. Olası olgunun hızlı tanımlanması ve diğer hastalardan izole…
Position: 14066 (21 views)