440 10 20655 https://www.socictopen.socict.org/files/original/0110aba2fb39fff4760812c4ec559c16.pdf 2bc155efb6427229b19eeec941bfef90 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Introducción Dossier AREA 27 “Procesos urbanos globales. Hacia un mundo mejor” Creator An entity primarily responsible for making the resource David Kullock, José Seguinot Barbosa Description An account of the resource Cuando la Dirección de AREA propuso dedicar un número de la revista a un dossier titulado “Procesos urbanos globales. Hacia un mundo mejor” sabíamos que se enfrentaba un desafío singular, dado que la agenda académica urbanística que venía ampliamente dedicada a las crecientes amenazas del Cambio Climático, comenzaba a abocarse a las incógnitas sobre el futuro urbano que podría surgir tras la pandemia de la COVID-19. En ese escenario, proponer “la detección de fenómenos […] que incidan positivamente sobre la conformación y el futuro de los asentamientos humanos” resultaba temerario o, al menos, poco proclive a tener éxito. A pesar de ello y quizás incidido por los disloques personales que se acentuaron por la prolongación del aislamiento social durante el año 2021, las propuestas de artículos empezaron a llegar y alcanzaron a ser una veintena. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource Diseño, area, arquitectura, dossier, introducción, reflexión Source A related resource from which the described resource is derived Area Publisher An entity responsible for making the resource available Universidad de Buenos Aires. Facultad de Arquitectura, Diseño y Urbanismo Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Urban groups. The city. Urban sociology, Architecture Relation A related resource <a href="https://publicacionescientificas.fadu.uba.ar/index.php/area/article/view/1919" target="_blank" rel="noreferrer noopener">https://publicacionescientificas.fadu.uba.ar/index.php/area/article/view/1919</a> https://www.socictopen.socict.org/files/original/e0009411a280cb325dfc239b34504a4d.pdf 02300727e356632deed64f44406f2366 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Rapid recovery of taste and smell in a patient with SARS-CoV-2 following convalescent plasma therapy. Creator An entity primarily responsible for making the resource David L Fisher, Alin Pavel, Stephen Malnick Date A point or period of time associated with an event in the lifecycle of the resource 2021 Identifier An unambiguous reference to the resource within a given context 10.1093/qjmed/hcaa341 Source A related resource from which the described resource is derived QJM : monthly journal of the Association of Physicians https://www.socictopen.socict.org/files/original/539377e70989443fd364316eb4650e8f.pdf 5aab465167636d91faf08451e9e9a4d6 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Multi-omic network signatures of disease Creator An entity primarily responsible for making the resource David L Gibbs, Lisa E Gralinski, Ralph S. Baric, Shannon K McWeeney Description An account of the resource To better understand dynamic disease processes, integrated multi-omic methods are needed, yet comparing different types of omic data remains difficult. Integrative solutions benefit experimenters by eliminating potential biases that come with single omic analysis.We have developed the methods needed to explore whether a relationship exists between co-expression network models built from transcriptomic and proteomic data types, and whether this relationship can be used to improve the disease signature discovery process. A naïve, correlation based method is utilized for comparison. Using publicly available infectious disease time series data, we analyzed the related co-expression structure of the transcriptome and proteome in response to SARS-CoV infection in mice. Transcript and peptide expression data was filtered using quality scores and subset by taking the intersection on mapped Entrez IDs. Using this data set, independent co-expression networks were built. The networks were integrated by constructing a bipartite module graph based on module member overlap, module summary correlation, and correlation to phenotypes of interest. Compared to the module level results, the naïve approach is hindered by a lack of correlation across data types, less significant enrichment results, and little functional overlap across data types. Our module graph approach avoids these problems, resulting in an integrated omic signature of disease progression, which allows prioritization across data types for down-stream experiment planning. Integrated modules exhibited related functional enrichments and could suggest novel interactions in response to infection. These disease and platform-independent methods can be used to realize the full potential of multi-omic network signatures. Date A point or period of time associated with an event in the lifecycle of the resource 2014 Subject The topic of the resource proteomics, Transcription, Genetic, transfection, Virology, omics, biomarkers Identifier An unambiguous reference to the resource within a given context DOI: 10.3389/fgene.2013.00309 Source A related resource from which the described resource is derived Frontiers in Genetics Publisher An entity responsible for making the resource available Frontiers Media S.A. Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Genetics Language A language of the resource EN https://www.socictopen.socict.org/files/original/d1b8ba59f7dc9b12a30e85e0f81a1570.pdf f48a87ba5ee5f67aa41b518c73b637ae Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Global Surveillance, National Surveillance, and SARS Creator An entity primarily responsible for making the resource David L. Heymann, Guénaël Rodier Date A point or period of time associated with an event in the lifecycle of the resource 2004 Subject The topic of the resource China Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid1002.031038 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/a1bece44fec11ce06ae29f51e112d025.pdf 304b3eae37353cd693aa6dd9e311079b Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The climatic-environmental significance, status and socio- economic perspective of the grown-shade coffee agroecosystems in the central mountain region of Veracruz, Mexico Creator An entity primarily responsible for making the resource David Loreto, Manuel Esperón-Rodríguez, Víctor L. Barradas Description An account of the resource Resumen . El clima y la vegetación coexisten en un equilibrio dinámico. Sin embargo, la falta de vegetación puede causar cambios climáticos locales y regionales. Los agroecosistemas del café de sombra proveen recursos, servicios ambientales y beneficios socio-económicos. Se encontró que la producción de café ha disminuido pero su valor económico ha incre- mentado; sin embargo, los indicadores socio-económicos han disminuido. La alta tasa de deforestación está causando cambios en los patrones de precipitación y en la frecuencia de niebla, lo que contribuye a la crisis ambiental y socio- económica de la región. Este trabajo presenta un análisis de la influencia del clima local y regional en el café cultivado a sombra en el área central de Veracruz, así como los factores que intervienen en el cambio de uso de suelo con las respec- tivas consecuencias para los productores de café. Date A point or period of time associated with an event in the lifecycle of the resource 2017 Subject The topic of the resource Café cereza, Coffea arabica, agro, café cultivado a la sombra, ecosistemas, ingresos y bienestar de los productores, unidades de producción Source A related resource from which the described resource is derived Investigaciones Geográficas Publisher An entity responsible for making the resource available Universidad Nacional Autónoma de México Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Geography (General), Geography. Anthropology. Recreation Relation A related resource <a href="http://www.redalyc.org/articulo.oa?id=56950566008" target="_blank" rel="noreferrer noopener">http://www.redalyc.org/articulo.oa?id=56950566008</a> https://www.socictopen.socict.org/files/original/54d40099d1f8d2d91b90b7408d8b7a44.pdf e008093fa72b57f05a6ee6b98cf69427 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource COPD & COVID-19. Creator An entity primarily responsible for making the resource David M G Halpin, Claus F Vogelmeier, Alvar A Agusti Date A point or period of time associated with an event in the lifecycle of the resource 2021 Identifier An unambiguous reference to the resource within a given context 10.1016/j.arbres.2021.01.001 Source A related resource from which the described resource is derived Archivos de bronconeumologia https://www.socictopen.socict.org/files/original/59b46c5b09c84fc60cee93f76bcaec06.pdf 021f9444f497fc0af838070417c16962 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Human Mycobacterium tuberculosis CD8 T Cell Antigens/Epitopes Identified by a Proteomic Peptide Library. Creator An entity primarily responsible for making the resource David M Lewinsohn, Gwendolyn M Swarbrick, Meghan E Cansler, Megan D Null, Veena Rajaraman, Marisa M Frieder, David R Sherman, Shannon McWeeney, Deborah A. Lewinsohn Description An account of the resource Identification of CD8(+) T cell antigens/epitopes expressed by human pathogens with large genomes is especially challenging, yet necessary for vaccine development. Immunity to tuberculosis, a leading cause of mortality worldwide, requires CD8(+) T cell immunity, yet the repertoire of CD8 antigens/epitopes remains undefined. We used integrated computational and proteomic approaches to screen 10% of the Mycobacterium tuberculosis (Mtb) proteome for CD8 Mtb antigens. We designed a weighting schema based upon a Multiple Attribute Decision Making:framework to select 10% of the Mtb proteome with a high probability of containing CD8(+) T cell epitopes. We created a synthetic peptide library consisting of 15-mers overlapping by 11 aa. Using the interferon-γ ELISPOT assay and Mtb-infected dendritic cells as antigen presenting cells, we screened Mtb-specific CD8(+) T cell clones restricted by classical MHC class I molecules (MHC class Ia molecules), that were isolated from Mtb-infected humans, against this library. Three novel CD8 antigens were unambiguously identified: the EsxJ family (Rv1038c, Rv1197, Rv3620c, Rv2347c, Rv1792), PE9 (Rv1088), and PE_PGRS42 (Rv2487c). The epitopes are B5701-restricted EsxJ24-34, B3905-restricted PE953-67, and B3514-restricted PE_PGRS4248-56, respectively. The utility of peptide libraries in identifying unknown epitopes recognized by classically restricted CD8(+) T cells was confirmed, which can be applied to other intracellular pathogens with large size genomes. In addition, we identified three novel Mtb epitopes/antigens that may be evaluated for inclusion in vaccines and/or diagnostics for tuberculosis. Date A point or period of time associated with an event in the lifecycle of the resource 2013 Identifier An unambiguous reference to the resource within a given context DOI: 10.1371/journal.pone.0067016 Source A related resource from which the described resource is derived PLoS ONE Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Science, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/38cb875b1897560ebc2e3c83bec23b10.pdf c312890793a369f764e758c5099e2cf2 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Effect of adeno-associated virus (AAV)-mediated overexpression of PEPCK-M (Pck2) on Clenbuterol-induced muscle growth. Creator An entity primarily responsible for making the resource David M Loczenski-Brown, Sarah Jones, Jeni Luckett, Zoe Daniel, Madelaine C Brearley, Francis J. P. Ebling, Tim Parr, John M Brameld Description An account of the resource We previously identified PEPCK-M (encoded by the Pck2 gene) to be highly up-regulated in skeletal muscle of pigs treated with Ractopamine, an anabolic beta-adrenergic receptor agonist. To determine whether PEPCK-M had a causative role in modulating the skeletal muscle growth response to Ractopamine, we used adeno-associated virus 1 (AAV1) to over-express Pck2 (AAV-Pck2) in murine skeletal muscle. A contralateral limb design was employed, such that each mouse served as its own control (injected with a GFP-only expressing AAV1, labelled AAV-GFP). Daily injections of Clenbuterol (1 mg/kg for 21 days) or vehicle control were also carried out to assess the effects of AAV-Pck2 overexpression on the anabolic response to a beta-adrenergic agonist. AAV-Pck2 overexpression in leg muscles of male C57BL6/J mice for 4 weeks (6-10 weeks of age) increased Pck2 mRNA (~100-fold), protein (not quantifiable) and enzyme activity (~3-fold). There was a trend (p = 0.0798) for AAV-Pck2 overexpression to reduce TA muscle weights, but there was no significant effect on muscle fibre diameters or myosin heavy chain isoform (MyHC) mRNA expression. When skeletal muscle growth was induced by daily administration of Clenbuterol (for 21 days), overexpression of AAV-Pck2 had no effect on the growth response, nor did it alter the expression of Phosphoserine Aminotransferase-1 (Psat1) or Asparagine Synthetase (Asns) mRNA or the Clenbuterol-induced decreases in MyHC IIa and IIx mRNA expression (p = 0.0065 and p = 0.0267 respectively). However AAV-Pck2 overexpression reduced TA muscle weights (p = 0.0434), particularly in the Control (vehicle treated) mice (p = 0.059 for AAV x Clenbuterol interaction) and increased the expression of Seryl-tRNA Synthetase (Sars) mRNA (p = 0.0477). Hence, contrary to the original hypothesis, AAV-Pck2 overexpression reduced TA muscle weights and did not mimic or alter the muscle hypertrophic effects of the beta-adrenergic agonist, Clenbuterol. Date A point or period of time associated with an event in the lifecycle of the resource 2019 Identifier An unambiguous reference to the resource within a given context DOI: 10.1371/journal.pone.0218970 Source A related resource from which the described resource is derived PLoS ONE Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Science, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/37d3f24c6af2260862c2cdb901cd72e7.pdf 44dcca5c96905bb3d4d8645f7ad712d7 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coordinated Response to SARS, Vancouver, Canada Creator An entity primarily responsible for making the resource David M Patrick, Mel Krajden, Elizabeth Bryce, Allison McGeer, Diane L Roscoe, Robert C Brunham, Tim F. Booth, Martin Petric, Michael A Noble, Babak Pourbohloul, William R Bowie, Robert A. Parker, Danuta M Skowronski, Joan Tomblin, S. Aleina Tweed, Patricia Daly, Swee-Han Goh, Patrick W. Doyle, Tung C. Yang, Thomas L. Perry Description An account of the resource Two Canadian urban areas received travelers with severe acute respiratory syndrome (SARS) before the World Health Organization issued its alert. By July 2003, Vancouver had identified 5 cases (4 imported); Toronto reported 247 cases (3 imported) and 43 deaths. Baseline preparedness for pandemic threats may account for the absence of sustained transmission and fewer cases of SARS in Vancouver. Date A point or period of time associated with an event in the lifecycle of the resource 2006 Subject The topic of the resource Outbreak, nosocomial infections, coronavirus, dispatch, SARS, emerging pathogens Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid1201.050327 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine https://www.socictopen.socict.org/files/original/3a01b29b60c59d10f723f1afffc50c3b.pdf ae3646c32c853aa9649debc2e92e4e6f Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Clinical Implications of Chloroquine and Hydroxychloroquine Ototoxicity for COVID-19 Treatment: A Mini-Review Creator An entity primarily responsible for making the resource David M. Baguley, Pattarawadee Prayuenyong, Anand V. Kasbekar Description An account of the resource At this time of the COVID-19 pandemic, potentially effective treatments are currently under urgent investigation. Benefits of chloroquine and hydroxychloroquine for the treatment of COVID-19 infection have been proposed and clinical trials are underway. Chloroquine and hydroxychloroquine, typically used for the treatment of malaria and autoimmune diseases, have been considered for off-label use in several countries. In the literature, there are reports of ototoxic effects of the drugs causing damage to the inner ear structures, which then result in hearing loss, tinnitus, and/or imbalance. This mini-review represents a summary of the findings from a systematic search regarding ototoxicity of chloroquine and hydroxychloroquine in the published literature. The characteristics of sensorineural hearing loss and/or tinnitus after chloroquine or hydroxychloroquine treatment can be temporary but reports of persistent auditory and vestibular dysfunction exist. These are not frequent, but the impact can be substantial. Additionally, abnormal cochleovestibular development in the newborn was also reported after chloroquine treatment in pregnant women. The suggested dose of chloroquine for COVID-19 infection is considerably higher than the usual dosage for malaria treatment; therefore, it is plausible that the ototoxic effects will be greater. There are potential implications from this review for survivors of COVID-19 treated with chloroquine or hydroxychloroquine. Patient reports of hearing loss, tinnitus, or imbalance should be noted. Those with troublesome hearing loss, tinnitus and/or imbalance are encouraged to be referred for hearing evaluation and interventions once they are stable. Clinical trials of chloroquine or hydroxychloroquine should also consider including audiological monitoring in the protocol. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource tinnitus, Hearing Loss, chloroquine, hydroxychloroquine, ototoxicity, COVID-19 Identifier An unambiguous reference to the resource within a given context DOI: 10.3389/fpubh.2020.00252 Source A related resource from which the described resource is derived Frontiers in Public Health Publisher An entity responsible for making the resource available Frontiers Media S.A. Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Public aspects of medicine