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CDC42 Use in Viral Cell Entry Processes by RNA Viruses
The cellular actin cytoskeleton presents a barrier that must be overcome by many viruses, and it has become increasingly apparent many viral species have developed a diverse repertoire of mechanisms to hijack cellular actin-regulating signalling…
Position: 8719 (27 views)
Potential Global-Local Inconsistency in Species-Area Relationships Fitting
The Species-Area Relationship (SAR) has been widely employed to assess species diversity and predict species extinction. Thus far, although many functions were proposed to fit SAR based on field observations or simulation results, the shape of SAR…
Position: 2450 (47 views)
Longitudinal study of age-specific pattern of coronavirus infection in Lyle’s flying fox (Pteropus lylei) in Thailand
Abstract Background Bats are natural reservoirs for several highly pathogenic and novel viruses including coronaviruses (CoVs) (mainly Alphacoronavirus and Betacoronavirus). Lyle’s flying fox (Pteropus lylei)‘s roosts and foraging sites are usually…
Position: 12087 (23 views)
Further Evidence for Bats as the Evolutionary Source of Middle East Respiratory Syndrome Coronavirus
The evolutionary origins of Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) are unknown. Current evidence suggests that insectivorous bats are likely to be the original source, as several 2c CoVs have been described from various…
Position: 13049 (22 views)
The Membrane Protein of Severe Acute Respiratory Syndrome Coronavirus Functions as a Novel Cytosolic Pathogen-Associated Molecular Pattern To Promote Beta Interferon Induction via a Toll-Like-Receptor-Related TRAF3-Independent Mechanism
Most of the intracellular pattern recognition receptors (PRRs) reside in either the endolysosome or the cytoplasm to sense pathogen-derived RNAs, DNAs, or synthetic analogs of double-stranded RNA (dsRNA), such as poly(I:C). However, it remains…
Position: 10240 (25 views)
Harnessing DNA Synthesis to Develop Rapid Responses to Emerging and Pandemic Pathogens
Given the interconnected nature of our world today, emerging pathogens and pandemic outbreaks are an ever-growing threat to the health and economic stability of the global community. This is evident by the recent 2009 Influenza A (H1N1) pandemic,…
Position: 9449 (26 views)
Development of a Real-time PCR test for porcine group A rotavirus diagnosis
Group A Rotavirus (RVA) is one of the most common causes of diarrhea in humans and several animal species. A SYBR-Green Real-Time polymerase chain reaction (PCR) was developed to diagnose RVA from porcine fecal samples, targeting amplification of a…
Position: 272 (88 views)
Description of a new genus and species of Candonopsini (Crustacea, Ostracoda, Candoninae) from the alluvial valley of the Upper Parana River (Brazil, South America)
The genus Candobrasilopsis gen. nov. is here described, with C. rochai gen. nov. sp. nov. as type species, from the alluvial valley of the Upper Paraná River. The enigmatic Candonopsis brasiliensis Sars, 1901 is here redescribed and transferred to…
Position: 3840 (39 views)
The systematization of diagnosis of influenza like syndrome and severe acute respiratory syndrome by NHE-SCS
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Position: 16092 (19 views)
Diversidade genotípica de rotavírus suínos no Estado de São Paulo Diversity of porcine rotavirus genotypes in São Paulo State, Brazil
Rotavírus é uma das causas mais comuns de diarréia tanto em humanos quanto em diferentes espécies animais. Foi conduzido um estudo transversal a partir de 144 amostras fecais diarréicas colhidas de leitões, provenientes de 16 criações comerciais…
Position: 6333 (31 views)