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Design, Synthesis and Biological Evaluation of Novel Bromophenol Derivatives Incorporating Indolin-2-One Moiety as Potential Anticancer Agents
A series of bromophenol derivatives containing indolin-2-one moiety were designed and evaluated that for their anticancer activities against A549, Bel7402, HepG2, HeLa and HCT116 cancer cell lines using MTT assay in vitro. Among them, seven compounds…
Position: 4580 (36 views)
Modern Immunotropic Therapy of Patients with Coronavirus Infections
Objective: to analyze the immune status of patients with coronavirus infections (CVI) and to improve the effectiveness of their treatment by including into the conventional scheme of a drug with antiviral and immunotropic action. Materials and…
Position: 9455 (26 views)
Adaptive Information Dissemination Control to Provide Diffdelay for the Internet of Things
Applications running on the Internet of Things, such as the Wireless Sensor and Actuator Networks (WSANs) platform, generally have different quality of service (QoS) requirements. For urgent events, it is crucial that information be reported to the…
Position: 8031 (28 views)
Structure Related Inhibition of Enzyme Systems in Cholinesterases and BACE1 In Vitro by Naturally Occurring Naphthopyrone and Its Glycosides Isolated from Cassia obtusifolia
Cassia obtusifolia Linn. have been used to improve vision, inflammatory diseases, and as hepatoprotective agents and to promote urination from ancient times. In the present study, we investigated the influence of glycosylation of components of C.…
Position: 4895 (35 views)
Candidates in Astroviruses, Seadornaviruses, Cytorhabdoviruses and Coronaviruses for +1 frame overlapping genes accessed by leaky scanning
Abstract Background Overlapping genes are common in RNA viruses where they serve as a mechanism to optimize the coding potential of compact genomes. However, annotation of overlapping genes can be difficult using conventional gene-finding software.…
Position: 1095 (60 views)
Ocorrência do subtipo B do vírus da imunodeficiência felina em gatos domésticos da região sul do estado do Rio Grande do Sul, Brasil
No Brasil existem poucos estudos sobre a ocorrência da infecção pelo vírus da imunodeficiência felina (FIV), assim como a determinação dos subtipos circulantes, o que é indispensável para o desenvolvimento de vacinas e novos testes diagnósticos. O…
Position: 4311 (37 views)
SARS: un ejemplo de respuesta y colaboración.
Position: 383 (80 views)
A QSTR-Based Expert System to Predict Sweetness of Molecules
This work describes a novel approach based on advanced molecular similarity to predict the sweetness of chemicals. The proposed Quantitative Structure-Taste Relationship (QSTR) model is an expert system developed keeping in mind the five principles…
Position: 596 (71 views)
Vomiting and wasting disease associated with hemagglutinating encephalomyelitis viruses infection in piglets in jilin, china
Abstract One coronavirus strain was isolated from brain tissues of ten piglets with evident clinical manifestations of vomiting, diarrhea and dyskinesia in Jilin province in China. Antigenic and genomic characterizations of the virus (isolate…
Position: 3104 (43 views)
Identification and Diagnosis of Newly Emerging Pathogens
Emerging infectious diseases (EIDs) are newly identified or known infectious diseases that have either expanded in geographic range or increased in infection prevalence over the previous two decades. During the last three decades, more than 30 EIDs…
Position: 1595 (54 views)