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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Agricultura sostenible</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Agricultura sostenible</text>
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            <name>Title</name>
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                <text>A reunião especializada sobre agricultura familiar do Mercosul (REAF): expansão ou aprofundamento da integração regional?</text>
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            <name>Creator</name>
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              <elementText elementTextId="158711">
                <text>Guilherme Augusto Guimarães Ferreira</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="158712">
                <text>No início do século XXI, ocorreu um movimento de reforma institucional do Mercosul, marcado pela incorporação de diversos setores políticos e econômicos à institucionalidade do bloco, dentre os quais a agricultura familiar, no âmbito da Reunião Especializada sobre Agricultura Familiar do Mercosul (REAF). Assim sendo, este artigo realiza um estudo da REAF enquanto experiência de integração regional, com foco analítico nas dinâmicas de interação entre os governos e as organizações sociais do campo. Quer-se discutir em que medida as características da REAF indicam indícios de pressões para a superação do intergovernamentalismo e criação de mecanismos supranacionais. Por fim, defende-se que a supracitada reforma implementada no Mercosul resultou na proliferação de espaços de negociação sem poder de decisão, reproduzindo o modelo intergovernamental dos anos 1990.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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              <elementText elementTextId="158713">
                <text>2019</text>
              </elementText>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="158714">
                <text>integração regional. mercosul. reaf</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="158715">
                <text>10.22456/2178-8839.88352</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="158716">
                <text>Revista Conjuntura Austral</text>
              </elementText>
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          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="158717">
                <text>Graduate Programme in International Strategic Studies (PPGEEI)</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="158718">
                <text>International relations</text>
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            <name>Relation</name>
            <description>A related resource</description>
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              <elementText elementTextId="158719">
                <text>&lt;a href="https://seer.ufrgs.br/ConjunturaAustral/article/view/88352" target="_blank" rel="noreferrer noopener"&gt;https://seer.ufrgs.br/ConjunturaAustral/article/view/88352&lt;/a&gt;</text>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
                </elementText>
              </elementTextContainer>
            </element>
          </elementContainer>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="9862">
                <text>A reverse genetics system for avian coronavirus infectious bronchitis virus based on targeted RNA recombination</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="9863">
                <text>Steven  J. van Beurden, Alinda J. Berends, Annika Krämer-Kühl, Dieuwertje Spekreijse, Gilles Chénard, Hans-Christian Philipp, Egbert Mundt, Peter J.M. Rottier, M. Hélène Verheije</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="9864">
                <text>Abstract Background Avian coronavirus infectious bronchitis virus (IBV) is a respiratory pathogen of chickens that causes severe economic losses in the poultry industry worldwide. Major advances in the study of the molecular biology of IBV have resulted from the development of reverse genetics systems for the highly attenuated, cell culture-adapted, IBV strain Beaudette. However, most IBV strains, amongst them virulent field isolates, can only be propagated in embryonated chicken eggs, and not in continuous cell lines. Methods We established a reverse genetics system for the IBV strain H52, based on targeted RNA recombination in a two-step process. First, a genomic and a chimeric synthetic, modified IBV RNA were co-transfected into non-susceptible cells to generate a recombinant chimeric murinized (m) IBV intermediate (mIBV). Herein, the genomic part coding for the spike glycoprotein ectodomain was replaced by that of the coronavirus mouse hepatitis virus (MHV), allowing for the selection and propagation of recombinant mIBV in murine cells. In the second step, mIBV was used as the recipient. To this end a recombination with synthetic RNA comprising the 3′-end of the IBV genome was performed by introducing the complete IBV spike gene, allowing for the rescue and selection of candidate recombinants in embryonated chicken eggs. Results Targeted RNA recombination allowed for the modification of the 3′-end of the IBV genome, encoding all structural and accessory genes. A wild-type recombinant IBV was constructed, containing several synonymous marker mutations. The in ovo growth kinetics and in vivo characteristics of the recombinant virus were similar to those of the parental IBV strain H52. Conclusions Targeted RNA recombination allows for the generation of recombinant IBV strains that are not able to infect and propagate in continuous cell lines. The ability to introduce specific mutations holds promise for the development of rationally designed live-attenuated IBV vaccines and for studies into the biology of IBV in general.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="9865">
                <text>2017</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="9866">
                <text>avian coronavirus, infectious bronchitis virus, Mouse hepatitis virus, Targeted RNA recombination, Reverse genetics system, vaccine development</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="9867">
                <text>DOI: 10.1186/s12985-017-0775-8</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="9868">
                <text>Virology Journal</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="9869">
                <text>BMC</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="9870">
                <text>Infectious and parasitic diseases</text>
              </elementText>
            </elementTextContainer>
          </element>
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            <name>Language</name>
            <description>A language of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="9871">
                <text>EN</text>
              </elementText>
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          <name>Dublin Core</name>
          <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
          <elementContainer>
            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="1">
                  <text>Coronavirus</text>
                </elementText>
              </elementTextContainer>
            </element>
            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
                </elementText>
              </elementTextContainer>
            </element>
          </elementContainer>
        </elementSet>
      </elementSetContainer>
    </collection>
    <itemType itemTypeId="1">
      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="22275">
                <text>A reverse transcription loop-mediated isothermal amplification (LAMP) assay for the detection of feline Coronavirus</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="22276">
                <text>Angelica Stranieri, Stefania Lauzi, Alessia Giordano, Saverio Paltrinieri</text>
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            </elementTextContainer>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="22277">
                <text>Loop-mediated isothermal amplification (LAMP) is a molecular method that amplifies DNA under  isothermal conditions. It relies on the use of 4 different primers recognizing 6 regions of the template sequence and on the use of a DNA polymerase with strand displacement activity (Notomi et al., 2000). The addition of two loop primers allows the reaction time to be of one hour only (Nagamine et al., 2002). The aim of this study was to develop a reverse transcription LAMP assay for an easy and inexpensive detection of feline Coronavirus (FCoV). Six primers binding the conserved 3’UTR region of the FCoV were designed with the Primer Explorer software. Thirty-two samples of RNA (11 feces, 8 effusions, 9 blood samples and 4 tissues) on which a reverse transcription polymerase chain reaction (RT-PCR) for the 3’UTR region was performed were used. The reaction was carried out in 25μL reaction volume and the mixture was incubated in a thermocycler at 63°C for 1 hour followed by 10 minutes at 80°C. LAMP products were visualized under UV after electrophoresis migration on a 1.5% agarose gel stained with ethidium bromide, where they produce a ladder-like pattern if positive. Results where compared with those obtained on standard PCR. Sensitivity and specificity were respectively 60% and 100% on feces, 40% and 100% on effusions, 25% and 100% on blood, and 100% and 100% on tissues. The overall sensitivity and specificity of this method were of 57.1% and 100%, thus limiting a clinical application of this method, except for tissues.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="22278">
                <text>2016</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="22279">
                <text>LAMP, Feline coronavirus, PCR</text>
              </elementText>
            </elementTextContainer>
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          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="22280">
                <text>DOI: 10.13130/2283-3927/7075</text>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="22281">
                <text>International Journal of Health, Animal Science and Food Safety</text>
              </elementText>
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          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="22282">
                <text>Università degli Studi di Milano</text>
              </elementText>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="22283">
                <text>Genetics, Ecology, Animal culture, Economic biology</text>
              </elementText>
            </elementTextContainer>
          </element>
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            <name>Language</name>
            <description>A language of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="22284">
                <text>EN</text>
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          <name>Dublin Core</name>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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              </elementTextContainer>
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            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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              </elementTextContainer>
            </element>
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    <itemType itemTypeId="1">
      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="69996">
                <text>A Review of Human Mobility Research Based on Big Data and Its Implication for Smart City Development</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="69997">
                <text>Anqi Wang, Anshu Zhang, Edwin H.W. Chan, Wenzhong Shi, Xiaolin Zhou, Zhewei Liu</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="69998">
                <text>Along with the increase of big data and the advancement of technologies, comprehensive data-driven knowledge of urban systems is becoming more attainable, yet the connection between big-data research and its application e.g., in smart city development, is not clearly articulated. Focusing on Human Mobility, one of the most frequently investigated applications of big data analytics, a framework for linking international academic research and city-level management policy was established and applied to the case of Hong Kong. Literature regarding human mobility research using big data are reviewed. These studies contribute to (1) discovering the spatial-temporal phenomenon, (2) identifying the difference in human behaviour or spatial attributes, (3) explaining the dynamic of mobility, and (4) applying to city management. Then, the application of the research to smart city development are scrutinised based on email queries to various governmental departments in Hong Kong. The identified challenges include data isolation, data unavailability, gaming between costs and quality of data, limited knowledge derived from rich data, as well as estrangement between public and private sectors. With further improvement in the practical value of data analytics and the utilization of data sourced from multiple sectors, paths to achieve smarter cities from policymaking perspectives are highlighted.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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              <elementText elementTextId="69999">
                <text>2021</text>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>Hong Kong, covid-19, Big Data, human mobility, spatiotemporal human activity, smart city policy</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="70001">
                <text>10.3390/ijgi10010013</text>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="70002">
                <text>Epidemiology and Health</text>
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          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="70003">
                <text>Korean Society of Epidemiology</text>
              </elementText>
            </elementTextContainer>
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          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="70004">
                <text>Geography (General)</text>
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                <text>A review of long-term corneal preservation techniques: Relevance and renewed interests in the COVID-19 era</text>
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                <text>Sunita Chaurasia, Sujata Das, Aravind Roy</text>
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                <text>The growth of eye banking in India was showing positive trends until the nation was hit by unprecedented times as a result of the COVID-19 pandemic. The impact of this has led to a downward spiraling in eye banking activities globally. Several measures had to be implemented to tide over the crisis and strategies planned for future to prepare for the needs of corneal transplantation. While eye banks in India have been practicing short- term and intermediate storage preservation media, there is a definite need to evolve other methods of very long-term preservation. This review discusses various methods of long term corneal preservation, their relevance and applications in the present times. We reviewed relevant medical literature in English from PUBMED with the key words “Corneal preservation”, “Cryopreservation”, “Glycerol preservation”, Gamma Irradiation”, “Eye Banking” ,”COVID-19”.</text>
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                <text>covid-19, Eye Banking, cryopreservation, corneal preservation medium, gamma irradiated cornea, glycerol preservation</text>
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                <text>10.4103/ijo.IJO_1505_20</text>
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                <text>Biotemas</text>
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                <text>Universidade Federal de Santa Catarina</text>
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                <text>Ophthalmology</text>
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                <text>A Review of Novel Coronavirus, cause of Middle East Respiratory Syndrome</text>
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                <text>Katayoun Vahdat, Azam Amini, Akram Najafi, Mohammad Javad Haeri‌nejad</text>
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                <text>Abstract Background: Isolation of a novel virus belonging to coronavirdae family in September 2012, from patients in Middle East who had died of an acute respiratory illness &amp; renal failure lead to researches on this new virus. Here, a brief review to summarize the events of scientific findings of this new emerging virus. Material and Methods: This review is based on a comprehensive search of three databases (Pubmed, Embase and Cochrane) and WHO reports. The searched keywords were new coronavirus, Middle East, acute respieratory distress syndrom &amp; Saudi Arabia. Results: Due to novelty of virus only limited papers exist on searched databases, so only 50 papers were identified which after omitting repeated case reports, papers related to SARS and updated WHO reports, 30 papers were finally reviewed. Conclusion: WHO recommendation is evaluation of all patients with acute respiratory illness and history of travel to Saudi Arabia or other countries where this novel virus is epidemic.</text>
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                <text>Iranian South Medical Journal</text>
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                <text>Bushehr University of Medical Sciences</text>
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                <text>Medicine (General)</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>A Review of Potential Antiviral Drugs and Vaccines to Treat COVID-19</text>
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                <text>Sanjeet Singh, R Jayaram</text>
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                <text>Coronavirus disease 19 (COVID-19) is a challenge to the whole humanity. COVID-19 was first reportedin China and rigorous researches are going on for developing vaccine for the pandemic. This review wasprepared by following PRISMA guidelines and used the resources from the Web of Science and PubMed.This research focuses on the niches of symptoms and vaccines for COVID-19. The research for vaccineinvolves research for new vaccine and drug repurposing. Out of various drug repurposing options,Remdesivir, and Favipiravir, Chloroquine and Lopinavir/Ritonavir were found to be the popular onesfor treating COVID-19 patients across the world. Even though there are concerns regarding asymptoticpatients, the most dominant symptoms of COVID-19 are fever and cough, followed by Dyspnoea andmuscle ache. This review concludes that the COVID-19 related research should focus on developingimmunity vaccines, and repurposing of drugs. Research on the problems of quarantine life, patientmonitoring, and usage of information technology in facing COVID-19 will improve the quality of patienthandling during the pandemic. The research on the effectiveness of various models of lockdown andregulation of social life during lockdown periods, improving the safety of health care workers in theworkplace will definitely help the governments in their fight against COVID-19.</text>
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            <name>Subject</name>
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                <text>vaccine, coronavirus, Pandemic, SARS-CoV-2, COVID-19</text>
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            <description>An unambiguous reference to the resource within a given context</description>
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                <text>DOI: 10.22207/JPAM.14.SPL1.14</text>
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            <description>A related resource from which the described resource is derived</description>
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                <text>Journal of Pure and Applied Microbiology</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>Journal of Pure and Applied Microbiology</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Microbiology</text>
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              <name>Title</name>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>A Review of Recent Advances towards the Development of (Quantitative) Structure-Activity Relationships for Metallic Nanomaterials</text>
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                <text>Guang-Chao-Chen, Martina G. Vijver, Yinlong Xiao, Willie J. G. M. Peijnenburg</text>
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                <text>Gathering required information in a fast and inexpensive way is essential for assessing the risks of engineered nanomaterials (ENMs). The extension of conventional (quantitative) structure-activity relationships ((Q)SARs) approach to nanotoxicology, i.e., nano-(Q)SARs, is a possible solution. The preliminary attempts of correlating ENMs’ characteristics to the biological effects elicited by ENMs highlighted the potential applicability of (Q)SARs in the nanotoxicity field. This review discusses the current knowledge on the development of nano-(Q)SARs for metallic ENMs, on the aspects of data sources, reported nano-(Q)SARs, and mechanistic interpretation. An outlook is given on the further development of this frontier. As concluded, the used experimental data mainly concern the uptake of ENMs by different cell lines and the toxicity of ENMs to cells lines and Escherichia coli. The widely applied techniques of deriving models are linear and non-linear regressions, support vector machine, artificial neural network, k-nearest neighbors, etc. Concluded from the descriptors, surface properties of ENMs are seen as vital for the cellular uptake of ENMs; the capability of releasing ions and surface redox properties of ENMs are of importance for evaluating nanotoxicity. This review aims to present key advances in relevant nano-modeling studies and stimulate future research efforts in this quickly developing field of research.</text>
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                <text>nano-(Q)SARs, metallic nanomaterials, Risk assessment, cellular uptake, toxicity</text>
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                <text>DOI: 10.3390/ma10091013</text>
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                <text>MDPI AG</text>
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                <text>Technology, Engineering (General). Civil engineering (General), Electrical engineering. Electronics. Nuclear engineering, Microscopy, Descriptive and experimental mechanics</text>
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                <text>Yung-Fang Tu, Chian-Shiu Chien, Aliaksandr A Yarmishyn, Yi-Ying Lin, Yung-Hung Luo, Yi-Tsung Lin, Wei-Yi Lai, Deming Yang, Shih-Jie Chou, Yiping Yang, Mong-Lien Wang, Shih-Hwa Chiou</text>
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            <description>An account of the resource</description>
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                <text>The sudden outbreak of 2019 novel coronavirus (2019-nCoV, later named SARS-CoV-2) in Wuhan, China, which rapidly grew into a global pandemic, marked the third introduction of a virulent coronavirus into the human society, affecting not only the healthcare system, but also the global economy. Although our understanding of coronaviruses has undergone a huge leap after two precedents, the effective approaches to treatment and epidemiological control are still lacking. In this article, we present a succinct overview of the epidemiology, clinical features, and molecular characteristics of SARS-CoV-2. We summarize the current epidemiological and clinical data from the initial Wuhan studies, and emphasize several features of SARS-CoV-2, which differentiate it from SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV), such as high variability of disease presentation. We systematize the current clinical trials that have been rapidly initiated after the outbreak of COVID-19 pandemic. Whereas the trials on SARS-CoV-2 genome-based specific vaccines and therapeutic antibodies are currently being tested, this solution is more long-term, as they require thorough testing of their safety. On the other hand, the repurposing of the existing therapeutic agents previously designed for other virus infections and pathologies happens to be the only practical approach as a rapid response measure to the emergent pandemic, as most of these agents have already been tested for their safety. These agents can be divided into two broad categories, those that can directly target the virus replication cycle, and those based on immunotherapy approaches either aimed to boost innate antiviral immune responses or alleviate damage induced by dysregulated inflammatory responses. The initial clinical studies revealed the promising therapeutic potential of several of such drugs, including favipiravir, a broad-spectrum antiviral drug that interferes with the viral replication, and hydroxychloroquine, the repurposed antimalarial drug that interferes with the virus endosomal entry pathway. We speculate that the current pandemic emergency will be a trigger for more systematic drug repurposing design approaches based on big data analysis.</text>
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            <name>Date</name>
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                <text>2020</text>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="15935">
                <text>SARS-CoV-2, COVID-19, Pneumonia, Clinical trials, immunotherapy, vaccine</text>
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          <element elementId="43">
            <name>Identifier</name>
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                <text>DOI: 10.3390/ijms21072657</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="15937">
                <text>International Journal of Molecular Sciences</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="15938">
                <text>MDPI AG</text>
              </elementText>
            </elementTextContainer>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Biology (General), Chemistry</text>
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            <description>A language of the resource</description>
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              <elementText elementTextId="15940">
                <text>EN</text>
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          </element>
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        <src>https://www.socictopen.socict.org/files/original/6c921de76cc7a2348e74db4a00df5387.pdf</src>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                <elementText elementTextId="1">
                  <text>Coronavirus</text>
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              </elementTextContainer>
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            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="36885">
                <text>A Review of the 2019 Novel Coronavirus (Covid-19): Immunopathogenesis, Molecular Biology and Clinical Aspects</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="36886">
                <text>Mohsen Khaki, Ghasem Mosayebi, Ali Ganji, ali Ghazavi</text>
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            </elementTextContainer>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="36887">
                <text>Background and Aim: COVID-19, a viral respiratory illness. In this review, we discuss issues such as the genetic structure, pathogenic mechanism, clinical characteristics, diagnosis, treatment, and prevention of COVID-19 based on the latest findings. Materials and Methods: The Medline was searched for terms such as “Coronavirus” ،“ COVID-19” and “Respiratory infection”. Findings: In December 2019, the unprecedented outbreak of pneumonia with unknown etiology began in Wuhan, Hubei Province, China. The cause was a new coronavirus, named COVID-19 by the WHO. This virus has high transmissibility and affects the lower respiratory tract. Research into the mechanism and treatment of COVID-19 is under way, and new information is being provided every day, some of which are contradictory. COVID-19 is a serious and dangerous infectious disease and a significant threat to the health of the world's population, and should be prevented from spreading rapidly. Conclusion: Because the exact mechanisms of the disease have not been fully elucidated and specific drug or vaccine have not yet been developed for it, control is mainly based on the interruption of the transmission cycle.</text>
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          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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              <elementText elementTextId="36888">
                <text>2020</text>
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            </elementTextContainer>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="36889">
                <text>coronavirus, respiratory infection, COVID-19</text>
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          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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                <text>DOI: </text>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="36891">
                <text>Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk</text>
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          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="36892">
                <text>Arak Medical University</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="36893">
                <text>Medicine (General), Medicine</text>
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            </elementTextContainer>
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