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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Deep-learning: investigating deep neural networks hyper-parameters and comparison of performance to shallow methods for modeling bioactivity data</text>
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                <text>Alexios Koutsoukas, Keith J. Monaghan, Xiaoli LI, Jun Huan</text>
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                <text>Abstract Background In recent years, research in artificial neural networks has resurged, now under the deep-learning umbrella, and grown extremely popular. Recently reported success of DL techniques in crowd-sourced QSAR and predictive toxicology competitions has showcased these methods as powerful tools in drug-discovery and toxicology research. The aim of this work was dual, first large number of hyper-parameter configurations were explored to investigate how they affect the performance of DNNs and could act as starting points when tuning DNNs and second their performance was compared to popular methods widely employed in the field of cheminformatics namely Naïve Bayes, k-nearest neighbor, random forest and support vector machines. Moreover, robustness of machine learning methods to different levels of artificially introduced noise was assessed. The open-source Caffe deep-learning framework and modern NVidia GPU units were utilized to carry out this study, allowing large number of DNN configurations to be explored. Results We show that feed-forward deep neural networks are capable of achieving strong classification performance and outperform shallow methods across diverse activity classes when optimized. Hyper-parameters that were found to play critical role are the activation function, dropout regularization, number hidden layers and number of neurons. When compared to the rest methods, tuned DNNs were found to statistically outperform, with p value</text>
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                <text>2017</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>deep learning, SARS, Cheminformatics, machine learning, Data mining, random forest</text>
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                <text>DOI: 10.1186/s13321-017-0226-y</text>
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            <name>Source</name>
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              <elementText elementTextId="21873">
                <text>Journal of Cheminformatics</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>BMC</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Chemistry, Information technology</text>
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                  <text>Agricultura sostenible</text>
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                  <text>Dominio científico: Agricultura sostenible</text>
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                <text>Morfometría y morfología de estomas y de polen como indicadores indirectos de poliploidía en especies del género Polylepis (Rosaceae) en Ecuador</text>
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            <description>An entity primarily responsible for making the resource</description>
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                <text>Alexis Debut, Joselin C. Caiza, Dominique Vargas, Camila Olmedo, Mario Arboleda, Anahi Boada, Osmar Acurio, María C. Segovia-Salcedo</text>
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                <text>Los bosques de Polylepis (Familia: Rosaceae), originarios de los Andes, son considerados como uno de los ecosistemas boscosos más amenazados. A lo largo de su historia evolutiva se evidenciaron varios episodios de poliploidía que impactaron en sus procesos de especiación. Las estructuras celulares como el polen y células oclusivas se encuentran muy influenciadas por la cantidad de genes presentes en cada especie, por lo que representa un método indirecto para determinar el grado de ploidía. En este estudio se analizó la relación del tamaño del grano de polen y la longitud de las células oclusivas con el tamaño del genoma y el número cromosómico, además de la viabilidad polínica de Polylepis incana, P. pauta, P. microphylla, P. racemosa y P. sericea recolectadas en los páramos andinos del Ecuador. Se fotografiaron granos de polen y estomas con un aumento de 400X y se midió su longitud en micrómetros con el programa ImageJ 1.49v. Para determinar la viabilidad del polen se utilizó una técnica de tinción. Los resultados muestran que existe una correlación positiva que varía de R2=0.32 a R2=0.65 entre las variables empleadas, según la especie, por lo cual sirven para analizar indirectamente la poliploidía. Estos datos son relevantes para el manejo y la conservación de Polylepis en Ecuador, ya que permiten identificar de antemano, rápida y económicamente potenciales citotipos e individuos híbridos a lo largo de los Andes ecuatorianos. Además, abre la posibilidad tanto de utilizar estos datos en estudios de cambio climático como para determinar parentales en proyectos de reforestación y restauración.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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              <elementText elementTextId="148111">
                <text>2018</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>Andes, análisis morfológico, células oclusivas, microgameto, ploidia</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="148113">
                <text>10.25260/EA.18.28.1.1.528</text>
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            <description>A related resource from which the described resource is derived</description>
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                <text>Ecología Austral</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>Asociación Argentina de Ecología</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Environmental sciences, Ecology</text>
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            <description>A related resource</description>
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                <text>&lt;a href="http://ojs.ecologiaaustral.com.ar/index.php/Ecologia_Austral/article/view/528" target="_blank" rel="noreferrer noopener"&gt;http://ojs.ecologiaaustral.com.ar/index.php/Ecologia_Austral/article/view/528&lt;/a&gt;</text>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Agricultura sostenible</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Agricultura sostenible</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Sostenibilidad de la Agroindustria Nacional en términos de recursos naturales</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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                <text>Alexis Dueñas</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>El problema de la contribución del capital natural en las trayectorias decrecimiento de la agroindustria regional cobra actualidad y representaun estancamiento del crecimiento de la economía nacional basadaen actividades extractivas, en la cual la agroindustria, juega un rolimportante en la reactivación del crecimiento económico del país. Elobjetivo de este trabajo es determinar y establecer la influencia delcapital natural en las trayectorias de crecimiento de la agroindustria,en términos de producción, en el Perú. Los resultados obtenidos, encuanto a tasas de crecimiento, señalan que para la agroindustria detipo C3 tiene patrones mixtos, similar al caso de las cadenas del tipoC2 y C1. En cuanto, a presiones y cargas ambientales se halló una depresión del 15 al 25% para el suelo, del 25 y 40% para el agua, con unageneración de residuos sólidos (45 y 60%) para las cadenas del tipo C1.Se determinó que entre el 25 y 35% son las presiones en el suelo, y queel 40 a 45% de tales volúmenes descansan en las demandas de agua. Porotro lado, el 28 al 35% de los volúmenes producidos se traducen enresiduos para las cadenas C2, tendencia que es extensible a las cadenasC3. Se concluye que la agroindustria nacional sigue por el modeloexpansivo, es decir, a mayor crecimiento mayor consumo de capitalnatural (recursos naturales) y mayor generación de contaminantes.</text>
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            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2019</text>
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                <text>Agroindústria, capital natural, crecimiento y recursos naturales, sostenibilidad</text>
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                <text>10.24265/campus.2019.v24n28.04</text>
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                <text>Campus</text>
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              <elementText elementTextId="187684">
                <text>Universidad de San Martín de Porres</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Engineering (General). Civil engineering (General), Technology</text>
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                <text>&lt;a href="https://www.aulavirtualusmp.pe/ojs/index.php/rc/article/view/1650/1667" target="_blank" rel="noreferrer noopener"&gt;https://www.aulavirtualusmp.pe/ojs/index.php/rc/article/view/1650/1667&lt;/a&gt;</text>
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                <text>Estimación probabilística del cambio climático en Venezuela medianteun enfoque bayesiano Probabilistic Estimation of Climate Change in Venezuela using a Bayesian approach</text>
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                <text>ALEXIS DURÁN, LELYS GUENNI</text>
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                <text>El problema del cambio climático es uno de los grandes problemas ambientales que enfrenta la humanidad, ya que ligeras variaciones en las variables climáticas pueden traer graves consecuencias en las actividades económicas y el bienestar humano en general. Hoy en día los modelos de circulación general (MCG) de la atmósfera son la principal herramienta para estudiar los cambios climáticos. El Ministerio del Ambiente y de los Recursos Naturales (MARN) lideró en el año 2005 la Primera Comunicación Nacional en Cambio Climático de Venezuela, utilizando salidas de 16 MCGs a escala global (resolución de 5circ°imes 5circ), cuyas proyecciones estiman incrementos para la temperatura y disminución en la precipitación para los próximos años. Cada MCG arroja diferentes resultados generando incertidumbre en la señal del cambio climático futuro. Este trabajo utiliza un enfoque Bayesiano y una extensión del método Reliability Ensemble Average (REA) (Tebaldi et al. 2005), combinando las salidas (presente y futura) de precipitación y temperatura de los 16 MCG con observaciones de las condiciones climáticas actuales, con el fin de determinar las distribuciones de probabilidad del cambio climático futuro para estas dos variables climáticas en nueve regiones de Venezuela. Para el estudio se toman en cuenta dos criterios: sesgo, el cual considera la diferencia entre las salidas de los modelos y el clima actual, y convergencia, que cuantifica las diferencias en los cambios simulados por los múltiples modelos del clima futuro. El principal resultado obtenido del trabajo es que aún existe considerable incertidumbre en las proyecciones de los MCG, ya que estos no incluyen todos los aspectos sobre el funcionamiento del sistema climático. También se pudo establecer que mientras menor sea la variabilidad natural de la variable climática, más efectiva será su proyección.The changing climate is one of the main environmental problems facing humanity, since slight variations in the climate variables might have terrible consequences in the economic activities and human well-being. Nowadays atmospheric Global Circulation Models (GCMs) are the main tools to study changing climate. The Ministry of Environment and Natural Resources (MENR) led in 2005 the First Communication in Climate Change of Venezuela, using the outputs of 16 GCMs at a global scale (resolution of 5circ imes 5circ) whose projections estimate increasing temperature and diminishing precipitation in the coming years. Each GCM gives different results, generating uncertainty in the future changing climate signal. This work uses a Bayesian approach and an extension of the Reliability Ensemble Average (REA) (Tebaldi et al. 2005) method, combining the outputs (present and future) of precipitation and temperature of the 16 GCMs with observations of present climate conditions, to determine the probability distributions of future changing climate change for these two climate variables in 9 regions in Venezuela. For this study, two criteria are used: bias, which considers the difference between the model outputs and the present climate; and convergence, which quantifies the differences among the simulated changes of future climate by multiple models. The main result of this work is that a large amount of uncertainty still exists in the GCMs projections, since they as yet do not include all aspects of the climate system functioning. It was also concluded that the lower the natural variability in the climate variable, the more effective is its projection.</text>
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                <text>La industria agroalimentaria en la controversia del desarrollo sustentable</text>
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                <text>Alexis Mercado, Karenia Córdova</text>
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                <text>El sistema de producción global contraría los postulados del desarrollo sustentable. El creciente consumo de recursos naturales, el incremento de la contaminación, la concentración de la producción en pocas multinacionales y un acceso no equitativo a los alimentos, configuran un escenario desalentador en términos ambientales y sociales. Satisfacer necesidades básicas de la población no ha sido una prioridad de gran parte de la agroindustria, sector que por sus implicaciones, ocupa lugar central en esta controversia. Su carácter estratégico determina que reciba tratamiento preferencial por la mayoría de las naciones. Sin embargo, la implantación de normativas de inocuidad, calidad y ambiente definen trayectorias institucionales y tecnológicas uniformizantes que han contribuido a concentrar la producción y un perfil particular, muy parcial, de asumir el desafío de la sustentabilidad. En este 'orden global' se desarrollan también procesos socio-productivos basados en conocimientos locales y estructuras cooperativas, planteando estilos diferentes de desarrollo y de aproximación a la sustentabilidad.</text>
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                <text>Desarrollo sustentable, industria agroalimentaria, organización industrial</text>
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                <text>Estudios Sociales</text>
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                <text>Centro de Investigación en Alimentación y Desarrollo</text>
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                <text>Social sciences (General), Nutrition. Foods and food supply</text>
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                  <text>Dominio científico: Agricultura sostenible</text>
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                <text>ASMA BRONQUIAL: ALGUNOS FACTORES ASOCIADOS A SU GRADO DE SEVERIDAD</text>
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                <text>Alexis Osmanis Medina Quesada, Ismael Ferrer Herrera, Alberto A. Llanes Rodríguez, Orlando Suárez Ramírez, Nurys V. Quevedo Arnaiz</text>
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                <text>Se realizó un estudio descriptivo transversal para relacionar el grado de severidad del asma bronquial y algunos factores asociados en 173 asmáticos, de los consultorios 10 y 26 del Policlínico 'Ignacio Agramonte' del municipio Camagüey, durante el año 2003. Las variables estudiadas fueron los grupos de edades, sexo, factores contribuyentes, desencadenantes y clasificación según grado de severidad, se recogieron en una encuesta y los datos se procesaron automatizadamente. Los resultados mostraron un predominio del asma bronquial en el grupo de edades de uno a nueve años (25.43 %) y de 10¿19 años (23.70 %); de los intermitentes leves (43.35 %) y persistentes leves (21.97 %), del empleo del kerosene, carbón o leña (71.09 %) entre los factores contribuyentes y de los cambios climáticos (82.08 %) entre los desencadenantes. La exposición al tabaquismo entre los factores contribuyentes y a los cambios climáticos, los alérgenos inhalados, los ejercicios, los alimentos y los factores psicológicos entre los desencadenantes, se relacionaron con el aumento de la severidad del asma bronquial.</text>
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                <text>2006</text>
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                <text>Archivo Médico de Camagüey</text>
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              <elementText elementTextId="240781">
                <text>Universidad de Ciencias Médicas de Camagüey</text>
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                <text>Medicine, Medicine (General)</text>
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                <text>&lt;a href="http://www.redalyc.org/articulo.oa?id=211117629006" target="_blank" rel="noreferrer noopener"&gt;http://www.redalyc.org/articulo.oa?id=211117629006&lt;/a&gt;</text>
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                <text>Correction to: ESCAP CovCAP survey of heads of academic departments to assess the perceived initial (April/May 2020) impact of the COVID-19 pandemic on child and adolescent psychiatry services.</text>
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                <text>Alexis Revet, Johannes Hebebrand, Dimitris Anagnostopoulos, Laura A Kehoe, Paul Klauser</text>
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                <text>10.1007/s00787-021-01754-1</text>
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                <text>European child &amp; adolescent psychiatry</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Coronavirus and the need for strong government institutions: defeating the pandemic and reviving economies</text>
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                <text>Alexis S. Esposto</text>
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                <text>This paper discusses the importance of government and economic institutions in dealing with economic shocks such as the COVID-19. In attempting to deal with this massive health, social and economic upheaval, governments around the world have been using a variety of social and economic policies. These policies have two aims. First, to reduce the spread of the virus and second to mitigate the economy wide damage that the spread of the virus is causing. The paper describes the initial economic impact of the virus worldwide and on the Australian economy. It also argues that unless a rapid response is made, the likelihood of a world depression is high. The analysis focuses on the importance of government institutions in respond-ing to major economic shocks. It showcases the work of the Treasury of Australia as a model of best practice for the development of economic policies designed to respond to extreme events. The paper concludes by providing a set of economy wide policy responses to tackle the current economic shocks.</text>
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                <text>coronavirus, Australia, covid-19, crisis, institutions, shocks</text>
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                <text>Biotemas</text>
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                <text>Universidade Federal de Santa Catarina</text>
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                <text>Economic theory. Demography, Economic history and conditions</text>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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            <name>Title</name>
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                <text>Toronto Emergency Medical Services and SARS</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="7067">
                <text>Alexis Silverman, Andrew Simor, Mona R Loutfy</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2004</text>
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            <name>Subject</name>
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                <text>Letter, severe acute respiratory syndrome, Outbreak, emergency medical services, Management, Canada</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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                <text>DOI: 10.3201/eid1009.040170</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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                <text>Emerging Infectious Diseases</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="7072">
                <text>Centers for Disease Control and Prevention</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Infectious and parasitic diseases, Medicine</text>
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            </elementTextContainer>
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            <name>Language</name>
            <description>A language of the resource</description>
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                <text>EN</text>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Agricultura sostenible</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Agricultura sostenible</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Evaluación de rizobacterias promotoras del crecimiento bajo diferentes esquemas de fertilización en el cultivo de maíz variedad HIMECA-95</text>
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            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="144375">
                <text>Alexis Valerio Valery Ramirez, Isbelia Reyes</text>
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            <description>An account of the resource</description>
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                <text>Evaluation of growth promoting rhizobacteria under different fertilization schemes in maize variety HIMECA-95 Titulo corto: Biofertilización del maíz Resumen: Bacterias previamente aisladas, y caracterizadas como diazotróficas y disolventes de  fosfatos inorgánicos se evaluaron en campo como promotoras del crecimiento vegetal en la producción de maíz variando las condiciones de fertilidad del suelo. Las cepas MF1b y MF5, en forma individual y en consorcio, se inocularon en semillas de maíz (HIMECA-95), y se sembraron bajo las siguientes condiciones de fertilización química: K, NK, PK, RK, NPK, y NRK (R: roca fosfórica). Al final del ensayo se determinó el peso seco total, y los contenidos de N y de P presentes en el grano para luego calcular el porcentaje de eficiencia agronómica relativa (%EAR). Los resultados obtenidos mostraron que la inoculación con la cepa MF5 en forma individual y en consorcio, con una fertilización quimica de NK, incrementaron la EAR del peso seco del grano en 130 y 403%, el contenido de N en 463  y 116%,  y el de P en 152 y 376%, respectivamente, logrando un aumento en la producción del grano de maíz y su calidad. Asimismo, se observó una variabilidad en las respuestas de los parámetros evaluados, lo cual podría deberse a los bajos contenidos de N y P del suelo, a los cambios en la fertilidad del suelo por la adición de los fertilizantes de alta solubilidad, y a la interacción entre las comunidades microbianas autóctonas y las bacterias introducidas. Se concluye que la efectividad de los microorganismos con potencial como biofertilizante para la agricultura sea evaluada cuidadosamente bajo diversas condiciones de fertilidad de los suelos.   Palabras clave: PGPR, fertilidad del suelo,bacterias diazotróficas, consorcio bacteriano, rendimiento   Abstract: Bacteria previously isolated, characterized as diazotrophic and inorganic phosphate solubilizers were evaluated under field conditions as plant growth promoters on the maize production when soil fertility was changed. The strains MF1b and MF5, alone and in consortium, were inoculated on maize seeds (HIMECA-95), and these were sown under the following chemical fertility conditions: K, NK, PN, RK, NPK, and NRK (R: phosphate rock). Total dry weight, and N and P contents of the grain were determined at the end of the experiment; also, the % of relative agronomic efficiency (RAE) was calculated. Results showed that inoculation with the strain MF5 alone and in consortium, with the addition of NK fertilizer increased the % RAE in 130 and 403 for the dry weight, in 463 and 116 for the N content, and in 152 and 376 for the P content, respectively, allowing an increase in both production and grain quality. Moreover, it was observed variations among the evaluated parameters which could be related to the low N and P status of the soil, the soil fertility changes after the addition of the highly soluble chemical fertilizers, and the interaction between autochthonous microbial communities and the introduced bacteria. It is concluded that the affectivity of a potential microbial biofertilizer for agriculture should be carefully evaluated under different fertility conditions of soils. Key words: PGPR, soil fertility, diazotrophic, bacteria consortium, yield.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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              <elementText elementTextId="144377">
                <text>2013</text>
              </elementText>
            </elementTextContainer>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="144378">
                <text>biofertilizantes, biotecnología</text>
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            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="144379">
                <text>10.15446/rev.colomb.biote.v15n2.32294</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="144380">
                <text>Revista Colombiana de Biotecnología</text>
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            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="144381">
                <text>Universidad Nacional de Colombia</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="144382">
                <text>Biotechnology</text>
              </elementText>
            </elementTextContainer>
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          <element elementId="46">
            <name>Relation</name>
            <description>A related resource</description>
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              <elementText elementTextId="144383">
                <text>&lt;a href="https://revistas.unal.edu.co/index.php/biotecnologia/article/view/32294" target="_blank" rel="noreferrer noopener"&gt;https://revistas.unal.edu.co/index.php/biotecnologia/article/view/32294&lt;/a&gt;</text>
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