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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Coronavirus</text>
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                <text>Dominio científico: Coronavirus</text>
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              <text>Patients with Initial Negative RT-PCR and Typical Imaging of COVID-19: Clinical Implications</text>
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              <text>Florent Baicry, Pierrick  Le Borgne, Thibaut Fabacher, Martin Behr, Elena  Laura Lemaitre, Paul-Albert Gayol, Sébastien Harscoat, Nirvan Issur, Sabrina Garnier-Kepka, Mickael Ohana, Pascal Bilbault, Mathieu Oberlin</text>
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              <text>The sensitivity of reverse transcriptase polymerase chain reaction (RT-PCR) has been questioned due to negative results in some patients who were strongly suspected of having coronavirus disease 2019 (COVID-19). The aim of our study was to analyze the prognosis of infected patients with initial negative RT-PCR in the emergency department (ED) during the COVID-19 outbreak. This study included two cohorts of adult inpatients admitted into the ED. All patients who were suspected to be infected with SARS-CoV-2 and who underwent a typical chest CT imaging were included. Thus, we studied two distinct cohorts: patients with positive RT-PCR (PCR+) and those with negative initial RT-PCR (PCR–). The data were analyzed using Bayesian methods. We included 66 patients in the PCR– group and 198 in the PCR+ group. The baseline characteristics did not differ except in terms of a proportion of lower chronic respiratory disease in the PCR– group. We noted a less severe clinical presentation in the PCR– group (lower respiratory rate, lower oxygen need and mechanical ventilation requirement). Hospital mortality (9.1% vs. 9.6%) did not differ between the two groups. Despite an initially less serious clinical presentation, the mortality of patients infected by SARS-CoV-2 with a negative RT-PCR did not differ from those with positive RT-PCR.</text>
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              <text>2020</text>
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              <text>reverse transcriptase polymerase chain reaction, covid-19, clinical management, Bayesian analysis</text>
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              <text>10.3390/jcm9093014</text>
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          <name>Source</name>
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              <text>Epidemiology and Health</text>
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          <name>Publisher</name>
          <description>An entity responsible for making the resource available</description>
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              <text>Korean Society of Epidemiology</text>
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          <name>Coverage</name>
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              <text>Medicine</text>
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