https://www.socictopen.socict.org/files/original/72591034ca3fcaa414e8bc466f719b81.pdf 215060e40df4ba574f5ea9b458a65c29 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource HLA, Immune Response, and Susceptibility to COVID-19 Creator An entity primarily responsible for making the resource Gholamreza Hatam, Ahmad Zavaran Hosseini, Marjan Jeddi, Fataneh Tavasolian, Mohsen Rashidi, Sayed Hussain Mosawi, Sayed Hussain Mosawi, Elham Abdollahi, Robert D. Inman, Robert D. Inman Description An account of the resource The severe acute respiratory syndrome caused by Coronavirus 2 (SARS-CoV-2) that appeared in December 2019 has precipitated the global pandemic Coronavirus Disease 2019 (COVID-19). However, in many parts of Africa fewer than expected cases of COVID-19, with lower rates of mortality, have been reported. Individual human leukocyte antigen (HLA) alleles can affect both the susceptibility and the severity of viral infections. In the case of COVID-19 such an analysis may contribute to identifying individuals at higher risk of the disease and the epidemiological level to understanding the differences between countries in the epidemic patterns. It is also recognized that first antigen exposure influences the consequence of subsequent exposure. We thus propose a theory incorporating HLA antigens, the “original antigenic sin (OAS)” effect, and presentation of viral peptides which could explain with differential susceptibility or resistance to SARS-CoV-2 infections. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource Coronavirus disease 2019, immune response, vaccine design, human leukocyte antigens, original antigenic sin Identifier An unambiguous reference to the resource within a given context 10.3389/fimmu.2020.601886 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Immunologic diseases. Allergy