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                <text>Coronavirus</text>
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                <text>Dominio científico: Coronavirus</text>
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          <name>Title</name>
          <description>A name given to the resource</description>
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              <text>Membranous Replication Factories Induced by Plus-Strand RNA Viruses</text>
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              <text>Inés Romero-Brey, Ralf Bartenschlager</text>
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              <text>In this review, we summarize the current knowledge about the membranous replication factories of members of plus-strand (+) RNA viruses. We discuss primarily the architecture of these complex membrane rearrangements, because this topic emerged in the last few years as electron tomography has become more widely available. A general denominator is that two “morphotypes” of membrane alterations can be found that are exemplified by flaviviruses and hepaciviruses: membrane invaginations towards the lumen of the endoplasmatic reticulum (ER) and double membrane vesicles, representing extrusions also originating from the ER, respectively. We hypothesize that either morphotype might reflect common pathways and principles that are used by these viruses to form their membranous replication compartments.</text>
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              <text>2014</text>
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              <text>membrane rearrangements, electron microscopy, electron tomography, Ultrastructure, double membrane vesicles, membranous replication factories, hepatitis C virus, flaviviruses, picornaviruses, coronaviruses</text>
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              <text>DOI: 10.3390/v6072826</text>
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              <text>Viruses</text>
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              <text>MDPI AG</text>
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          <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <text>Microbiology</text>
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          <name>Language</name>
          <description>A language of the resource</description>
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              <text>EN</text>
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